Kevin M Ryan

researcher

Kevin M Ryan is …
instance of (P31):
humanQ5

External links are
P6178Dimensions author ID01105071425.30
P856official websitehttp://www.gla.ac.uk/researchinstitutes/cancersciences/staff/kevinryan/
P496ORCID iD0000-0002-1059-9681
P10861Springer Nature person ID01105071425.30

P69educated atUniversity of LiverpoolQ499510
Beatson Institute for Cancer ResearchQ25188472
P108employerUniversity of GlasgowQ192775
University of LiverpoolQ499510
P734family nameRyanQ5263823
RyanQ5263823
RyanQ5263823
P735given nameKevinQ605834
KevinQ605834
P106occupationresearcherQ1650915
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q35664079A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.
Q33694155Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B.
Q24339433Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy
Q38344632Analysis of E-box DNA binding during myeloid differentiation reveals complexes that contain Mad but not Max.
Q41813930Analysis of macroautophagy by immunohistochemistry
Q39583449Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells
Q37967998Autophagy and cancer
Q53269829Autophagy and cancer--issues we need to digest.
Q57247950Autophagy chews Fap to promote apoptosis
Q27000191Autophagy in malignant transformation and cancer progression
Q38115087Autophagy in tumour cell death
Q56609460Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations
Q98193823Autophagy, the innate immune response and cancer
Q37676660Autophagy: an adaptable modifier of tumourigenesis
Q45037005Cancer: Viruses' backup plan
Q57248011Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression
Q38345040Cell-cycle progression is not essential for c-Myc to block differentiation
Q33774492Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest
Q38313722DNA-binding independent cell death from a minimal proapoptotic region of E2F-1.
Q34000900DRAM links autophagy to p53 and programmed cell death
Q29616308DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
Q39443251DRAM-1 encodes multiple isoforms that regulate autophagy
Q40991336DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose
Q28508710Differentiating embryonal stem cells are a rich source of haemopoietic gene products and suggest erythroid preconditioning of primitive haemopoietic stem cells
Q39296611Does androgen-ablation therapy (AAT) associated autophagy have a pro-survival effect in LNCaP human prostate cancer cells?
Q38310909E2F1 drives chemotherapeutic drug resistance via ABCG2.
Q48239259Emerging roles of transcriptional programs in autophagy regulation
Q37641677Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy
Q39163275Extracellular adenosine sensing-a metabolic cell death priming mechanism downstream of p53.
Q41924376Glucose-starved cells do not engage in prosurvival autophagy
Q57246314Growth factor signaling permits hypoxia-induced autophagy by a HIF1α-dependent, BNIP3/3L-independent transcriptional program in human cancer cells
Q21996341Guidelines for the use and interpretation of assays for monitoring autophagy
Q22676705Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Q23757358Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Q57248008Hemizygosity of the MAX Gene Locus in HL60 Cells
Q39844165Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity
Q57247993Hzf and hCAS/CSE1L: making the right choice in p53-mediated tumour suppression
Q37680934Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens
Q41099375Induction of DNA synthesis and apoptosis are separable functions of E2F-1.
Q43619366Inhibition of HIF-1- and wild-type p53-stimulated transcription by codon Arg175 p53 mutants with selective loss of functions
Q39349314Inhibition of autophagy impairs tumor cell invasion in an organotypic model
Q35516643Involvement of RNA Polymerase III in Immune Responses.
Q35550235Life and death decisions by E2F-1.
Q35031397Loss of autophagy causes a synthetic lethal deficiency in DNA repair.
Q47255105Loss of nuclear factor-kappaB is tumor promoting but does not substitute for loss of p53.
Q27026045Lysosomal proteins in cell death and autophagy
Q28118946MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity
Q38334174Mechanistic and predictive profiling of 5-Fluorouracil resistance in human cancer cells.
Q38735356Molecular definitions of autophagy and related processes.
Q47843948Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Q34062481Myc oncogenes: the enigmatic family
Q37981834New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy
Q41462289Oncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1.
Q39870608PUMA- and Bax-induced autophagy contributes to apoptosis
Q24631299Phosphorylation of Puma modulates its apoptotic function by regulating protein stability
Q57248001Pinning a change on p53
Q34245385Regulation and function of the p53 tumor suppressor protein
Q39155203Retrograde signaling from autophagy modulates stress responses.
Q57248006Role of NF-κB in p53-mediated programmed cell death
Q38144288Role of autophagy in cancer prevention, development and therapy
Q36609038Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.
Q35976600Splicing DNA-damage responses to tumour cell death.
Q28592817TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival
Q36919798Targeting the p53 family for cancer therapy: 'big brother' joins the fight.
Q33889383The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.
Q39496691The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy
Q37840892The multiple roles of autophagy in cancer
Q37642093The role of autophagy in tumour development and cancer therapy.
Q47768840Transcriptional regulation of autophagy and lysosomal function by bromodomain protein BRD4.
Q24316301Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapy
Q39422081Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system
Q41617373Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity
Q38929715Using enhanced-mitophagy to measure autophagic flux.
Q39808307c-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol-treated Ewing sarcoma cells
Q37204552iASPP inhibition: increased options in targeting the p53 family for cancer therapy.
Q34911119p53 activates ICAM-1 (CD54) expression in an NF-kappaB-independent manner
Q37812885p53 and autophagy in cancer: Guardian of the genome meets guardian of the proteome
Q29617084p53 and metabolism
Q57247984p53 and senescence: A little goes a long way
Q39634575p53 and senescence: a little goes a long way.
Q57247977p53 and tumor surveillance: Killer finds way to recruit assassins
Q39048945p53 status determines the role of autophagy in pancreatic tumour development
Q39738650p53-mediated induction of Noxa and p53AIP1 requires NFkappaB.
Q39631491p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival
Q38579148p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death
Q40170381p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death

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