First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio). (scientific article published on 17 June 2015)

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Q24286950

Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule

Q24291640

Improved tools for biological sequence comparison

Q24652199

ExPASy: The proteomics server for in-depth protein knowledge and analysis

Q24672230

MatGAT: an application that generates similarity/identity matrices using protein or DNA sequences

Q24791448

Basic local alignment search tool

Q25938991

Teleost fish mount complex clonal IgM and IgT responses in spleen upon systemic viral infection

Q27339024

Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

Q27678108

MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment

Q27860726

Comparative protein modelling by satisfaction of spatial restraints

Q27860866

Elephant shark genome provides unique insights into gnathostome evolution

Q28660739

Cloning, characterization, and expression pattern of Atlantic halibut (Hippoglossus hippoglossus L.) CD4-2, Lck, and ZAP-70.

Q30156059

Spidey: a tool for mRNA-to-genomic alignments

Q31028386

The genome sequence of Atlantic cod reveals a unique immune system

Q31029462

Contrasted TCRβ diversity of CD8+ and CD8- T cells in rainbow trout

Q31114908

Molecular cloning and characterization of carp (Cyprinus carpio L.) CD8beta and CD4-like genes

Q33304743

Characterization of rag1 mutant zebrafish leukocytes

Q33405474

IL-22 secreting CD4+ T cells in the patients with neuromyelitis optica and multiple sclerosis.

Q50946310

ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish.

Q54039174

Role of CD4(+) and CD8α(+) T cells in protective immunity against Edwardsiella tarda infection of ginbuna crucian carp, Carassius auratus langsdorfii.

Q54232624

Development and maturation of the immune system in zebrafish, Danio rerio: a gene expression profiling, in situ hybridization and immunological study.

Q54756091

Expression of CD4 on human peripheral blood neutrophils.

Q54794918

Intestinal T cells of Dicentrarchus labrax (L.): Gene expression and functional studies

Q63345399

Detection of surface and cytoplasmic CD4 on blood monocytes from normal and HIV-1 infected individuals

Q67679119

The effect of primary and secondary immunization on the lymphoid tissues of the carp,Cyprinus carpio L

Q72668288

Localization of immune complexes and heat-aggregated immunoglobulin in the carp Cyprinus carpio L

Q72676090

Channel catfish, Ictalurus punctatus, CD4-like molecules

Q79915446

Conservation of characteristics and functions of CD4 positive lymphocytes in a teleost fish

Q83311891

In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish

Q33905238

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

Q34149224

Cytokine Gene Expression in CD4 Positive Cells of the Japanese Pufferfish, Takifugu rubripes

Q34792309

Characterization of the human CD4 gene promoter: transcription from the CD4 gene core promoter is tissue-specific and is activated by Ets proteins

Q36487614

Essentials of Th17 cell commitment and plasticity

Q36730400

T follicular helper cell diversity and plasticity

Q36823844

Expanding roles for CD4⁺ T cells in immunity to viruses.

Q37150560

Type 2 immunity and wound healing: evolutionary refinement of adaptive immunity by helminths.

Q37213084

RUNX proteins in transcription factor networks that regulate T-cell lineage choice

Q37376016

Th9 cells: differentiation and disease.

Q37696777

Teleost intestinal immunology.

Q37787449

NF-κB: roles and regulation in different CD4(+) T-cell subsets

Q38081166

Teleost T and NK cell immunity

Q38105797

Two types of TNF-α exist in teleost fish: phylogeny, expression, and bioactivity analysis of type-II TNF-α3 in rainbow trout Oncorhynchus mykiss

Q39062100

Clonal growth of carp (Cyprinus carpio) T cells in vitro: long-term proliferation of Th2-like cells

Q39238461

Alloantigen-specific killing is mediated by CD8-positive T cells in fish.

Q39906563

Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio

Q39922677

Autofluorescence of viable cultured mammalian cells

Q40225122

A structural view of CD4 and CD8.

Q40569685

Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle

Q40943284

Complex complexes: signaling at the TCR.

Q41113361

Feeding common carp Cyprinus carpio with β-glucan supplemented diet stimulates C-reactive protein and complement immune acute phase responses following PAMPs injection

Q42218575

The teleostean liver as an immunological organ: Intrahepatic immune cells (IHICs) in healthy and benzo[a]pyrene challenged rainbow trout (Oncorhynchus mykiss).

Q42220027

Helper function of CD4⁺ lymphocytes in antiviral immunity in ginbuna crucian carp, Carassius auratus langsdorfii

Q42248772

Identification of anti-viral cytotoxic effector cells in the ginbuna crucian carp, Carassius auratus langsdorfii

Q42285331

Identification and characterization of a second CD4-like gene in teleost fish

Q42675204

CD4 and CD8 homologues in Japanese flounder, Paralichthys olivaceus: Differences in the expressions and localizations of CD4-1, CD4-2, CD8α and CD8β.

Q43488291

Identification of Treg-like cells in Tetraodon: insight into the origin of regulatory T subsets during early vertebrate evolution

Q43668975

A complex issue on CD4(+) T-cell subsets

Q43738079

A CD4 homologue in sea bass (Dicentrarchus labrax): molecular characterization and structural analysis

Q44537842

Cloning, expression, and characterization of fugu CD4, the first ectothermic animal CD4.

Q45025769

Comprehensive clarification of two paralogous interleukin 4/13 loci in teleost fish

Q46303368

CD4 homologues in Atlantic salmon

Q46662879

B cells in teleost fish act as pivotal initiating APCs in priming adaptive immunity: an evolutionary perspective on the origin of the B-1 cell subset and B7 molecules.

Q47073174

Identification, cloning and characterization of interleukin-17 and its family from zebrafish

Q47074164

Finding the genes in genomic DNA.

Q47835342

A CD4 homologue in Atlantic halibut (Hippoglossus hippoglossus): molecular cloning and characterisation

Q48071956

Evolution of the CD4 family: teleost fish possess two divergent forms of CD4 in addition to lymphocyte activation gene-3.

Q48084923

P275

Creative Commons Attribution 4.0 International

copyrighted

describes a project that uses

ImageJ

Q1659584

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

Danio rerio

Q169444

P304

page(s)

e0126378

P577

publication date

2015-06-17

P1433

published in

PLOS One

Q564954

P1476

title

First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio)

P478

volume

Reverse relations

cites work (P2860)

Q28083360	Along the Axis between Type 1 and Type 2 Immunity; Principles Conserved in Evolution from Fish to Mammals
Q37355622	CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell-like Populations and Diverse Mononuclear Phagocytes.
Q60920087	CD4: a vital player in the teleost fish immune system
Q42345326	Correction: First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio).
Q38985470	Estrogen-dependent seasonal adaptations in the immune response of fish
Q57181674	Functional conservation of a developmental switch in mammals since the Jurassic age
Q46188870	Identification and characterization of T reg-like cells in zebrafish
Q40120455	Identification of novel antigen candidates for a tuberculosis vaccine in the adult zebrafish (Danio rerio).
Q54246706	Identification of protective postexposure mycobacterial vaccine antigens using an immunosuppression-based reactivation model in the zebrafish.
Q49620526	Immune-Related Transcriptional Responses to Parasitic Infection in a Naturally Inbred Fish: Roles of Genotype and Individual Variation.
Q63369779	Interleukin 10 mutant zebrafish have an enhanced interferon gamma response and improved survival against a Mycobacterium marinum infection
Q98471292	Kinetics of T lymphocyte subsets and B lymphocytes in response to immunostimulants in flounder (Paralichthys olivaceus): implications for CD4+ T lymphocyte differentiation
Q37401619	Novel Teleost CD4-Bearing Cell Populations Provide Insights into the Evolutionary Origins and Primordial Roles of CD4+ Lymphocytes and CD4+ Macrophages.
Q26782996	T Cells in Fish
Q26745559	The Function of Fish Cytokines
Q47654181	The first wave of T lymphopoiesis in zebrafish arises from aorta endothelium independent of hematopoietic stem cells.
Q40915256	Two highly adhesive lactic acid bacteria strains are protective in zebrafish infected with Aeromonas hydrophila by evocation of gut mucosal immunity

P819	ADS bibcode	2015PLoSO..1026378Y
P356	DOI	10.1371/JOURNAL.PONE.0126378
P932	PMC publication ID	4470515
P698	PubMed publication ID	26083432
P5875	ResearchGate publication ID	278792709