Characterization of the human CD4 gene promoter: transcription from the CD4 gene core promoter is tissue-specific and is activated by Ets proteins

scientific article

Characterization of the human CD4 gene promoter: transcription from the CD4 gene core promoter is tissue-specific and is activated by Ets proteins is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1993PNAS...90.7739S
P356DOI10.1073/PNAS.90.16.7739
P932PMC publication ID47218
P698PubMed publication ID8356078
P5875ResearchGate publication ID14843380

P50authorDavid KlatzmannQ22248690
Patrick SalmonQ50284351
Bohdan WasylykQ56520189
P2093author name stringA Giovane
P2860cites workA novel modulator domain of Ets transcription factorsQ68134655
Expression of ets genes in mouse thymocyte subsets and T cellsQ69324990
Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tailQ24302036
Myb and Ets proteins cooperate in transcriptional activation of the mim-1 promoterQ24563107
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cellsQ27860599
Organization and expression of eucaryotic split genes coding for proteinsQ27861081
The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogeneQ28116777
The isolation and sequence of the gene encoding T8: a molecule defining functional classes of T lymphocytesQ28305975
The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lckQ28506433
Five intermediate complexes in transcription initiation by RNA polymerase IIQ29616444
Interaction of murine ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motifQ30990862
cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.Q31117684
Transcriptional activation by Sp1 as directed through TATA or initiator: specific requirement for mammalian transcription factor IIDQ33630942
Core promoter of the mouse myelin basic protein gene governs brain-specific transcription in vitroQ33921882
Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.Q34114085
Structure of the mouse gene encoding CD4 and an unusual transcript in brainQ34360014
Structure and expression of the human and mouse T4 genesQ34380179
TATA-binding protein is a classless factorQ35913516
Transcription initiation from the dihydrofolate reductase promoter is positioned by HIP1 binding at the initiation siteQ36717640
Expression of the CD4 gene requires a Myb transcription factorQ36964900
Phenotypic and functional stages in the intrathymic development of alpha beta T cellsQ37769126
Sequence-specific binding of human Ets-1 to the T cell receptor alpha gene enhancerQ38338362
PEA3 is a nuclear target for transcription activation by non-nuclear oncogenesQ38343225
The Ets family of transcription factorsQ40871575
The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteinsQ41080680
Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoterQ41612990
Tyrosyl Phosphorylation and Activation of MAP Kinases by p56lckQ41640086
Unusual intron in the immunoglobulin domain of the newly isolated murine CD4 (L3T4) geneQ45136118
Physical Analysis of Transcription Preinitiation Complex Assembly on a Class II Gene PromoterQ45226839
Viral myb oncogene encodes a sequence-specific DNA-binding activity.Q46760013
Identification of Ets- and notch-related subunits in GA binding proteinQ48214636
Isolation and sequence of L3T4 complementary DNA clones: expression in T cells and brainQ48285982
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene familyQ48376775
Transcriptional Control Signals of a Eukaryotic Protein-Coding GeneQ48403794
Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage.Q51161910
P433issue16
P407language of work or nameEnglishQ1860
P304page(s)7739-7743
P577publication date1993-08-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleCharacterization of the human CD4 gene promoter: transcription from the CD4 gene core promoter is tissue-specific and is activated by Ets proteins
P478volume90

Reverse relations

cites work (P2860)
Q55050138A Census of Tandemly Repeated Polymorphic Loci in Genic Regions Through the Comparative Integration of Human Genome Assemblies.
Q36551440A Myc-associated zinc finger protein binding site is one of four important functional regions in the CD4 promoter
Q40022809A conserved tissue-specific structure at a human T-cell receptor beta-chain core promoter
Q42058596A potential role for Elf-1 in CD4 promoter function
Q73838329A region in the CD8 gene locus that directs expression to the mature CD8 T cell subset in transgenic mice
Q40792734A transcriptional silencer controls the developmental expression of the CD4 gene.
Q35980019Activation of CD8+ T lymphocytes through the T cell receptor turns on CD4 gene expression: implications for HIV pathogenesis
Q37658449Beta-catenin signaling mediates CD4 expression on mature CD8+ T cells
Q33785272CD4 promoter transactivation by human herpesvirus 6.
Q38308352Characterization of regulatory elements in the 5'-flanking region of the GM2 activator gene.
Q45025769Cloning, expression, and characterization of fugu CD4, the first ectothermic animal CD4.
Q33716329Control of CD4 gene expression: connecting signals to outcomes in T cell development
Q35012095Controlling CD4 gene expression during T cell lineage commitment
Q24292737Cooperative interaction between ETS1 and GFI1 transcription factors in the repression of Bax gene expression
Q41173912Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.
Q41281933Defective activation and survival of T cells lacking the Ets-1 transcription factor
Q40996721Deletional and mutational analyses of the human CD4 gene promoter: characterization of a minimal tissue-specific promoter.
Q51705799Development of a transient CD4(+)CD8(+) T cell subset in the cervical lymph nodes following intratracheal instillation with an adenovirus vector.
Q36666636Elf-1 binds to a critical element in a second CD4 enhancer
Q42813205Establishment and characterization of choroid plexus carcinoma cell lines: connection between choroid plexus and immune systems
Q33933227Ets target genes: past, present and future
Q52271324Ets-2 and c-Myb act independently in regulating expression of the hematopoietic stem cell antigen CD34
Q35666087First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio).
Q24673853GA-binding protein factors, in concert with the coactivator CREB binding protein/p300, control the induction of the interleukin 16 promoter in T lymphocytes
Q42834456GA-binding protein-dependent transcription initiator elements. Effect of helical spacing between polyomavirus enhancer a factor 3(PEA3)/Ets-binding sites on initiator activity
Q39816246Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma.
Q24307532Genomic organization and chromosomal localization of the gene encoding human P-selectin glycoprotein ligand
Q71047954Identification and characterization of a human CD4 silencer
Q34088346Identification of human granzyme B promoter regulatory elements interacting with activated T-cell-specific proteins: implication of Ikaros and CBF binding sites in promoter activation.
Q41133897Identification of the major positive regulators of c-myb expression in hematopoietic cells of different lineages
Q33778442Implication of N-acetylglucosaminyltransferases III and V in cancer: gene regulation and signaling mechanism
Q33624495Inhibition of human immunodeficiency virus type 1 and vaccinia virus infection by a dominant negative factor of the interferon regulatory factor family expressed in monocytic cells
Q40649836Lactate-sensitive response elements in genes involved in hyaluronan catabolism
Q71808694Lipopolysaccharide (LPS) down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor (TNF) and IL-1β
Q73259593Multiple negative and positive cis-acting elements control the expression of the murine CD4 gene
Q40925483Negative regulation of CD4 expression in T cells by the transcriptional repressor ZEB.
Q39458972Negative regulation of CD4 gene expression by a HES-1-c-Myb complex
Q36364154Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes.
Q39182513Porcine CD4 promoters and enhancers can direct foreign gene expression in human cells
Q33616853Precise arrangement of factor-binding sites is required for murine CD4 promoter function
Q42818840Roles of an Ets motif and a novel CACGAC direct repeat in transcription of the murine dihydrolipoamide dehydrogenase (Dld) gene
Q38304489Sequence and functional properties of African green monkey CD4 silencer
Q36645738Specific expression of the human CD4 gene in mature CD4+ CD8- and immature CD4+ CD8+ T cells and in macrophages of transgenic mice
Q31965950Structural organization and promoter analysis of murine heat shock transcription factor-1 gene
Q36375090Subclass-specific nuclear localization of a novel CD4 silencer binding factor
Q42831809T cell-specific expression from Mo-MLV retroviral vectors containing a CD4 mini-promoter/enhancer
Q40598277T-cell co-receptors. The end of a frustrating search
Q35769445The CD4/CD8 lineage choice: new insights into epigenetic regulation during T cell development
Q36709971The DNA sequence encompassing the transcription start site of a TATA-less promoter contains enough information to drive neuron-specific transcription
Q34139373The Ets-transcription factor family in embryonic development: lessons from the amphibian and bird
Q41036218The acetyltransferase activity of CBP stimulates transcription
Q34762486The fat body cell-free system for tissue-specific transcription of plasma protien gene ofBombyx mori
Q36669879The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.
Q37384802The nfkb1 promoter is controlled by proteins of the Ets family
Q38331303The notch pathway intermediate HES-1 silences CD4 gene expression
Q41430431The role of Ets transcription factors in the development and function of the mammalian immune system
Q45864295Tolerance induced without immunosuppression in a T-lymphocyte suicide-gene therapy cardiac allograft model in mice
Q37116497Transcriptional regulation of mouse L-selectin
Q38352116Transcriptional regulation of the N-acetylglucosaminyltransferase V gene in human bile duct carcinoma cells (HuCC-T1) is mediated by Ets-1.
Q36363777Transcriptional regulation of the T cell antigen receptor zeta subunit: identification of a tissue-restricted promoter
Q24644349hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci

Search more.