Lipopolysaccharide (LPS) down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor (TNF) and IL-1β

scientific article published on 01 November 1995

Lipopolysaccharide (LPS) down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor (TNF) and IL-1β is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1365-2249.1995.TB03801.X
P953full work available at URLhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2249.1995.tb03801.x
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2249.1995.tb03801.x
https://academic.oup.com/cei/article-pdf/102/2/430/42203141/j.1365-2249.1995.tb03801.x.pdf
P932PMC publication ID1553416
P698PubMed publication ID7586702

P2093author name stringL. J. Montaner
S. Gordon
G. Herbein
A. G. Doyle
P2860cites workInterleukin-10 inhibits initial reverse transcription of human immunodeficiency virus type 1 and mediates a virostatic latent state in primary blood-derived human macrophages in vitroQ45789566
Treatment with recombinant IFN-gamma decreases cell surface CD4 levels on peripheral blood monocytes and on myelomonocyte cell lines.Q53517202
Transient modulation and internalization of T4 antigen induced by phorbol esters.Q54424003
Phorbol esters down-regulate transcription and translation of the CD4 geneQ67687104
Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding siteQ67969096
Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndromeQ68498654
Murine immunoglobulin G anti-CD4 monoclonal antibodies bind to primary human monocytes and macrophages through Fc receptors as well as authentic CD4Q68913135
Purified blood monocytes from HIV 1-infected patients produce high levels of TNF alpha and IL-1Q69177607
Purification of human monocytes on gelatin-coated surfacesQ69695474
Modulation of CD4 by antigenic activationQ70322737
Anti-Leu-3/T4 antibodies react with cells of monocyte/macrophage and Langerhans lineageQ70437878
HIV-1 induces tumour necrosis factor and IL-1 gene expression in primary human macrophages independent of productive infectionQ71615108
Interleukin-13 alters the activation state of murine macrophages in vitro: comparison with interleukin-4 and interferon-gammaQ72680200
Serine phosphorylation-independent downregulation of cell-surface CD4 by nefQ22251290
Adhesion versus coreceptor function of CD4 and CD8: role of the cytoplasmic tail in coreceptor activityQ24315140
Interaction between CD4 and class II MHC molecules mediates cell adhesionQ24339626
Reconstitution of the subclass-specific expression of CD4 in thymocytes and peripheral T cells of transgenic mice: identification of a human CD4 enhancerQ24680530
Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compoundsQ28339318
Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa BQ29618096
Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytesQ29619621
Class II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 moleculeQ33584112
CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration.Q34064274
Blockade of human immunodeficiency virus type 1 production in CD4+ T cells by an intracellular CD4 expressed under control of the viral long terminal repeatQ36193108
Loss of CD4 membrane expression and CD4 mRNA during acute human immunodeficiency virus replicationQ36355743
Interferons and bacterial lipopolysaccharide protect macrophages from productive infection by human immunodeficiency virus in vitroQ36356182
CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individualsQ36363328
Characterization of the human CD4 gene promoter: transcription from the CD4 gene core promoter is tissue-specific and is activated by Ets proteinsQ36487614
Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4.Q36655137
Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytesQ36659847
Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4Q36687143
Macrophage-tropic strains of human immunodeficiency virus type 1 utilize the CD4 receptorQ36783162
Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor.Q36831191
Disruption of the CD4-p56lck complex is required for rapid internalization of CD4Q37154861
CD4 and CD8 act as co-receptors during thymic selection of the T cell repertoireQ37354705
CD4: collaborator in immune recognition and HIV infectionQ37808725
In Vitro Infection of Monocytes with HIVBa-L. Effect on Cell Surface Expression of CD4, CD14, HLA-DR, and HLA-DQQ39242938
Depletion of the surface CD4 molecule by the envelope protein of human immunodeficiency virus expressed in a human CD4+ monocytoid cell lineQ40116744
A transcriptional silencer controls the developmental expression of the CD4 gene.Q40792734
Transcriptional and post-transcriptional regulation of TcR, CD4 and CD8 gene expression during activation of normal human T lymphocytes.Q41213547
A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte developmentQ41460845
IL-1 and tumor necrosis factor-alpha each up-regulate both the expression of IFN-gamma receptors and enhance IFN-gamma-induced HLA-DR expression on human monocytes and a human monocytic cell line (THP-1).Q41573212
The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pitsQ41632663
Interleukin 13 inhibits human immunodeficiency virus type 1 production in primary blood-derived human macrophages in vitro.Q41760887
Variations in CD4 expression by human monocytes and macrophages and their relationships to infection with the human immunodeficiency virusQ43621618
Modulation of surface antigens of a human monocyte cell line, U937, during incubation with T lymphocyte-conditioned medium: detection of T4 antigen and its presence on normal blood monocytesQ44145033
Loss of circulating T4+ monocytes in patients infected with HTLV-III.Q44248235
Cytokines alter production of HIV-1 from primary mononuclear phagocytesQ44548244
Macrophages rapidly internalize their tumor necrosis factor receptors in response to bacterial lipopolysaccharideQ44604819
Role of the L3T4-antigen in T cell activation. II. Inhibition of T cell activation by monoclonal anti-L3T4 antibodies in the absence of accessory cellsQ44844175
Human T lymphocytes and monocytes bear the same Leu-3(T4) antigenQ44886750
Human immunodeficiency virus infection of monocytic and T-lymphocytic cells: receptor modulation and differentiation induced by phorbol esterQ44890078
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectlipopolysaccharideQ421804
P304page(s)430-437
P577publication date1995-11-01
P1433published inClinical and Experimental ImmunologyQ15716708
P1476titleLipopolysaccharide (LPS) down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor (TNF) and IL-1 beta
Lipopolysaccharide (LPS) down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor (TNF) and IL-1β
P478volume102

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cites work (P2860)
Q3588450555- and 75-kilodalton tumor necrosis factor receptors mediate distinct actions in regard to human immunodeficiency virus type 1 replication in primary human macrophages
Q81439348Characterization of human peritoneal dendritic cell precursors and their involvement in peritonitis
Q33998211Down regulation of CD4 expression following isolation and culture of human monocytes
Q29622903Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.
Q48059413Effects of interleukin-1ß on cortical spreading depolarization and cerebral vasculature
Q37241492Expression and regulation of antiviral protein APOBEC3G in human neuronal cells
Q44030691HIV-1 envelope glycoprotein gp120 down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor-alpha
Q36136378Porphyromonas gingivalis-mediated signaling through TLR4 mediates persistent HIV infection of primary macrophages
Q93034297S100A14 Is Increased in Activated NK Cells and Plasma of HIV-Exposed Seronegative People Who Inject Drugs and Promotes Monocyte-NK Crosstalk
Q37433321TNF and TNF receptor superfamily members in HIV infection: new cellular targets for therapy?
Q33613493Targeting TNF and TNF Receptor Pathway in HIV-1 Infection: from Immune Activation to Viral Reservoirs
Q33785321Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains
Q33810779The macrophage in HIV-1 infection: from activation to deactivation?
Q35871524Tumor necrosis factor alpha inhibits entry of human immunodeficiency virus type 1 into primary human macrophages: a selective role for the 75-kilodalton receptor
Q73514015Xenograft rejection of fetal porcine islet-like cell clusters in the rat: effects of active and passive immunization

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