The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility

scientific article published on 9 June 2011

The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1165/RCMB.2011-0055OC
P932PMC publication ID3262664
P698PubMed publication ID21659657

P50authorNan LairdQ6962218
Augusto A LitonjuaQ42572197
John E HokansonQ89513456
P2093author name stringDavid A Lomas
Edwin K Silverman
James D Crapo
Michael H Cho
Peter J Castaldi
Terri H Beaty
Amund Gulsvik
Per Bakke
Wayne Anderson
COPDGene and Eclipse Investigators
P2860cites workIdentification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidneyQ24291483
Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complexQ24293265
Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase IIQ24338780
Genome-wide association study identifies five loci associated with lung functionQ24629653
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary functionQ24633262
Database resources of the National Center for Biotechnology InformationQ24644775
Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosisQ24645989
Molecular genetics of successful smoking cessation: convergent genome-wide association study resultsQ24653819
The natural history of chronic airflow obstructionQ24674578
PLINK: a tool set for whole-genome association and population-based linkage analysesQ24677407
A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysemaQ28205534
A role for the receptor for advanced glycation end products in idiopathic pulmonary fibrosisQ28507626
Genotype imputationQ29614590
Glutathione transferasesQ29616501
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.Q33419815
A genome-wide association study of pulmonary function measures in the Framingham Heart StudyQ33419839
The COPD genetic association compendium: a comprehensive online database of COPD genetic associationsQ33559787
Variants in FAM13A are associated with chronic obstructive pulmonary diseaseQ33687879
The natural history of forced expiratory volumes. Effect of cigarette smoking and respiratory symptomsQ34686548
MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7.Q37383035
RAGE and arthritis: the G82S polymorphism amplifies the inflammatory responseQ44032299
Pulmonary function between 6 and 18 years of age.Q46340194
The SERPINE2 gene is associated with chronic obstructive pulmonary disease in two large populations.Q53572756
Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE)Q57955885
P433issue6
P921main subjectgenome-wide association studyQ1098876
chronic obstructive pulmonary diseaseQ199804
P304page(s)1147-1153
P577publication date2011-06-09
P1433published inAmerican Journal of Respiratory Cell and Molecular BiologyQ4744268
P1476titleThe association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility
P478volume45

Reverse relations

cites work (P2860)
Q47639018A Genome-wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos.
Q55214049A candidate gene identification strategy utilizing mouse to human big-data mining: "3R-tenet" in COPD genetic research.
Q35860362A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry
Q63432937AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers
Q28387051APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema
Q42271746Acute and chronic inflammatory responses induced by smoking in individuals susceptible and non-susceptible to development of COPD: from specific disease phenotyping towards novel therapy. Protocol of a cross-sectional study
Q36842527Advanced glycation endproducts and their receptor in different body compartments in COPD
Q54522045Association of five genetic variants with chronic obstructive pulmonary disease susceptibility and spirometric phenotypes in a Chinese Han population.
Q34522806Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Chinese Han population: a case-control study
Q53286287Association of lung function genes with chronic obstructive pulmonary disease.
Q36176931CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland
Q26777324Candidate genes for COPD: current evidence and research
Q38636068Chronic Obstructive Pulmonary Disease Genetics: A Review of the Past and a Look Into the Future
Q91810031Cohort Profile: Extended Cohort for E-health, Environment and DNA (EXCEED)
Q36105702Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.
Q34004971Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease
Q35087187Comorbidities of COPD have a major impact on clinical outcomes, particularly in African Americans
Q37431463Copy number variation of the beta-defensin genes in europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma
Q36968835Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.
Q90076687Exposure to lipopolysaccharide (LPS) reduces contractile response of small airways from GSTCD-/- mice
Q45768914Functional polymorphisms in NFκB1/IκBα predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese
Q24337095GSTCD and INTS12 regulation and expression in the human lung
Q24630805Genes and chronic obstructive pulmonary disease
Q38974166Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects.
Q39851159Genetic Variants in IL6R and ADAM19 are Associated with COPD Severity in a Mexican Mestizo Population.
Q86038893Genetic linkage analysis identifies Pas1 as the common locus modulating lung tumorigenesis and acute inflammatory response in mice
Q30274832Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis
Q28596713Genetic regulation of expression of leukotriene A4 hydrolase
Q38700796Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice
Q38760182Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline
Q43792387Genetic variants in HHIP are associated with FEV1 in subjects with chronic obstructive pulmonary disease
Q39032868Genome-Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow-up
Q30420166Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction
Q38169066Lessons from ECLIPSE: a review of COPD biomarkers
Q36320879Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways
Q96306279Measures of lung function and their relationship with advanced glycation end-products
Q42235129Novel immune genes associated with excessive inflammatory and antiviral responses to rhinovirus in COPD.
Q36123192Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank
Q64250562Pathological Implications of Receptor for Advanced Glycation End-Product () Gene Polymorphism
Q27025295RAGE: a new frontier in chronic airways disease
Q54757715Receptor for advanced glycation end products and soluble receptor for advanced glycation end products: a balancing act in chronic obstructive pulmonary disease?
Q36392496Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation
Q51524555Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD.
Q35999518Susceptibility loci in lung cancer and COPD: association of IREB2 and FAM13A with pulmonary diseases.
Q43779676Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease
Q36257364Targeted Sequencing of Lung Function Loci in Chronic Obstructive Pulmonary Disease Cases and Controls
Q39312857The emerging role of NPNT in tissue injury repair and bone homeostasis.
Q38896877Traditional and emerging indicators of cardiovascular risk in chronic obstructive pulmonary disease.
Q34562154Variants in the 15q24/25 locus associate with lung function decline in active smokers
Q38026994What can genetics tell us about the cause of fixed airflow obstruction?
Q33553057Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.

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