| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1034446891 |
| P356 | DOI | 10.1038/NG.535 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/ng.535 |
| P932 | PMC publication ID | 2828499 |
| P698 | PubMed publication ID | 20173748 |
| P5875 | ResearchGate publication ID | 41510451 |
| P50 | author | Augusto A Litonjua | Q42572197 |
| Xiangyang Kong | Q64481933 | ||
| Ruth Tal-Singer | Q75469591 | ||
| John E Hokanson | Q89513456 | ||
| Edwin K Silverman | Q89513458 | ||
| Barbara J Klanderman | Q114440518 | ||
| P2093 | author name string | David Sparrow | |
| David A Lomas | |||
| Christoph Lange | |||
| Wayne H Anderson | |||
| Barry J Make | |||
| Craig P Hersh | |||
| Dawn L DeMeo | |||
| Elizabeth A Regan | |||
| James D Crapo | |||
| Michael H Cho | |||
| Terri H Beaty | |||
| Amund Gulsvik | |||
| Per Bakke | |||
| James R Murphy | |||
| Sungho Won | |||
| Gary M Hunninghake | |||
| Jody S Sylvia | |||
| John P Ziniti | |||
| Nadia Boutaoui | |||
| Sreekumar G Pillai | |||
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| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | chronic obstructive pulmonary disease | Q199804 |
| P304 | page(s) | 200-202 | |
| P577 | publication date | 2010-02-21 | |
| P1433 | published in | Nature Genetics | Q976454 |
| P1476 | title | Variants in FAM13A are associated with chronic obstructive pulmonary disease | |
| P478 | volume | 42 |
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| Q28387051 | APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema |
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| Q57909754 | Alpha-1 Antitrypsin PiMZ Genotype Is Associated with Chronic Obstructive Pulmonary Disease in Two Racial Groups |
| Q37303484 | An Adaptive Fisher's Combination Method for Joint Analysis of Multiple Phenotypes in Association Studies |
| Q38937853 | An ECLIPSE View of Alpha-1 Antitrypsin Deficiency |
| Q35961211 | An Interleukin 13 Polymorphism Is Associated with Symptom Severity in Adult Subjects with Ever Asthma |
| Q43136367 | An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people |
| Q26778098 | Anaesthesia for patient with chronic obstructive pulmonary disease |
| Q91582055 | Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene |
| Q33929376 | Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD |
| Q26767111 | Anesthetic considerations in the patients of chronic obstructive pulmonary disease undergoing laparoscopic surgeries |
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| Q33571299 | Association between fibroblast growth factor 7 and the risk of chronic obstructive pulmonary disease. |
| Q36490727 | Association of IREB2 Gene rs2568494 Polymorphism with Risk of Chronic Obstructive Pulmonary Disease: A Meta-Analysis. |
| Q36149225 | Association of cigarette smoking and CRP levels with DNA methylation in α-1 antitrypsin deficiency. |
| Q34522806 | Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Chinese Han population: a case-control study |
| Q53286287 | Association of lung function genes with chronic obstructive pulmonary disease. |
| Q37581425 | Association of nsv823469 copy number loss with decreased risk of chronic obstructive pulmonary disease and pulmonary function in Chinese |
| Q42689097 | Asthma and chronic obstructive pulmonary disease: common genes, common environments? |
| Q40114829 | Beyond GWAS in COPD: probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks |
| Q50894679 | Biomarkers for precision medicine in airways disease. |
| Q36176931 | CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland |
| Q58778491 | COPD is accompanied by co-ordinated transcriptional perturbation in the quadriceps affecting the mitochondria and extracellular matrix |
| Q35063488 | COPD: balancing oxidants and antioxidants |
| Q26777324 | Candidate genes for COPD: current evidence and research |
| Q58107063 | Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study |
| Q38636068 | Chronic Obstructive Pulmonary Disease Genetics: A Review of the Past and a Look Into the Future |
| Q27027955 | Chronic obstructive pulmonary disease |
| Q37731708 | Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema |
| Q88692203 | Common and Rare Variants Genetic Association Analysis of Cigarettes per Day Among Ever-Smokers in Chronic Obstructive Pulmonary Disease Cases and Controls |
| Q34004971 | Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease |
| Q34471260 | Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease |
| Q37834029 | Common pathogenic mechanisms and pathways in the development of COPD and lung cancer. |
| Q26864326 | Complex genetics of pulmonary diseases: lessons from genome-wide association studies and next-generation sequencing |
| Q37431463 | Copy number variation of the beta-defensin genes in europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma |
| Q98178406 | DNA Methylation: A Potential Biomarker of Chronic Obstructive Pulmonary Disease |
| Q41665058 | DNA methylation profiling in human lung tissue identifies genes associated with COPD. |
| Q57757087 | DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease |
| Q92029835 | DSP variants may be associated with longitudinal change in quantitative emphysema |
| Q28727447 | Different genes interact with particulate matter and tobacco smoke exposure in affecting lung function decline in the general population |
| Q37396382 | Differential DNA methylation marks and gene comethylation of COPD in African-Americans with COPD exacerbations |
| Q33766550 | Differential expression of vitamin E and selenium-responsive genes by disease severity in chronic obstructive pulmonary disease |
| Q34418291 | Disease risk factors identified through shared genetic architecture and electronic medical records |
| Q36691602 | Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility. |
| Q34982194 | EGLN2 and RNF150 genetic variants are associated with chronic obstructive pulmonary disease risk in the Chinese population |
| Q36099476 | Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function |
| Q92719088 | Effect of population stratification on SNP-by-environment interaction |
| Q36389310 | Emerging genetics of COPD. |
| Q50044127 | Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary disease. |
| Q34552656 | Epidemiology, radiology, and genetics of nicotine dependence in COPD. |
| Q98772259 | Epithelial cell-specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice |
| Q37125510 | Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease |
| Q37013121 | Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease |
| Q36968835 | Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12. |
| Q51638772 | Exon sequencing identifies a novel CHRNA3-CHRNA5-CHRNB4 variant that increases the risk for chronic obstructive pulmonary disease. |
| Q90470862 | FAM13A affects body fat distribution and adipocyte function |
| Q42775723 | FAM13A is associated with non-small cell lung cancer (NSCLC) progression and controls tumor cell proliferation and survival |
| Q42152998 | FAM13A locus in COPD is independently associated with lung cancer - evidence of a molecular genetic link between COPD and lung cancer |
| Q35410963 | Family history is a risk factor for COPD |
| Q48130979 | Family with sequence similarity 13, member A modulates adipocyte insulin signaling and preserves systemic metabolic homeostasis. |
| Q88355092 | Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research |
| Q37695214 | Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue |
| Q34441086 | Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese |
| Q35595026 | Gene susceptibility identification in a longitudinal study confirms new loci in the development of chronic obstructive pulmonary disease and influences lung function decline |
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| Q38974166 | Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects. |
| Q46417648 | Genetic Control of Fatty Acid β-Oxidation in Chronic Obstructive Pulmonary Disease |
| Q47171958 | Genetic Pleiotropy between Nicotine Dependence and Respiratory Outcomes |
| Q41449935 | Genetic Variants in the Hedgehog Interacting Protein Gene Are Associated with the FEV1/FVC Ratio in Southern Han Chinese Subjects with Chronic Obstructive Pulmonary Disease. |
| Q37166853 | Genetic association between human chitinases and lung function in COPD |
| Q36724956 | Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci |
| Q35108447 | Genetic determinants of chronic obstructive pulmonary disease in South Indian male smokers |
| Q36925216 | Genetic evidence linking lung cancer and COPD: a new perspective |
| Q30274832 | Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis |
| Q36229721 | Genetic polymorphism of heme oxygenase 1 promoter in the occurrence and severity of chronic obstructive pulmonary disease: a meta-analysis |
| Q37210556 | Genetic polymorphism of matrix metalloproteinase family and chronic obstructive pulmonary disease susceptibility: a meta-analysis |
| Q34342451 | Genetic polymorphisms and associated susceptibility to asthma |
| Q51700279 | Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction. |
| Q45074419 | Genetic studies as a tool for identifying novel potential targets for treatment of COPD. |
| Q34309196 | Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease |
| Q24606717 | Genetic susceptibility to lung cancer and co-morbidities |
| Q90211681 | Genetic underpinnings of lung function and COPD |
| Q38760182 | Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline |
| Q36148775 | Genetic variants associated with the risk of chronic obstructive pulmonary disease with and without lung cancer |
| Q55332454 | Genetic variants in FAM13A and IREB2 are associated with the susceptibility to COPD in a Chinese rural population: a case-control study. |
| Q34847876 | Genetic variation in HTR4 and lung function: GWAS follow-up in mouse |
| Q34500745 | Genetic variations in ADIPOQ gene are associated with chronic obstructive pulmonary disease |
| Q51716078 | Genetic variations in RORα are associated with chronic obstructive pulmonary disease. |
| Q34113954 | Genetics of asthma and allergy: what have we learned? |
| Q35092470 | Genetics of complex airway disease |
| Q34903148 | Genetics of complex respiratory diseases: implications for pathophysiology and pharmacology studies |
| Q28740314 | Genetics of sputum gene expression in chronic obstructive pulmonary disease |
| Q39568339 | Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets |
| Q29416995 | Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease |
| Q29417015 | Genome-wide association analysis of body mass in chronic obstructive pulmonary disease. |
| Q30427183 | Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. |
| Q28943477 | Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. |
| Q34425983 | Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns |
| Q30420166 | Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction |
| Q29416999 | Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema |
| Q28943334 | Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis |
| Q35923186 | Genome-wide association study of lung function decline in adults with and without asthma |
| Q29417072 | Genome-wide association study of smoking behaviours in patients with COPD |
| Q38960024 | Genome-wide genetic heterogeneity discovery with categorical covariates |
| Q34574923 | Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes |
| Q34300307 | Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD. |
| Q30408059 | Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study |
| Q38119867 | Heart failure and chronic obstructive pulmonary disease: the challenges facing physicians and health services |
| Q36155424 | Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study |
| Q37304387 | Heritability of chronic obstructive pulmonary disease and related phenotypes in smokers |
| Q37900349 | How the genetics of lung cancer may overlap with COPD. |
| Q35207735 | IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease |
| Q40214159 | IREB2, CHRNA5, CHRNA3, FAM13A & hedgehog interacting protein genes polymorphisms & risk of chronic obstructive pulmonary disease in Tatar population from Russia. |
| Q86573040 | Identification of FAM13A gene associated with the ratio of FEV1 to FVC in Korean population by genome-wide association studies including gene-environment interactions |
| Q35947849 | Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease |
| Q34238083 | Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP. |
| Q36372888 | Identifying a Deletion Affecting Total Lung Capacity Among Subjects in the COPDGene Study Cohort |
| Q38144104 | Immune response in chronic obstructive pulmonary disease |
| Q35542366 | Immunology, genetics and microbiota in the COPD pathophysiology: potential scope for patient stratification |
| Q34062965 | Impact of a functional polymorphism in the PAR-1 gene promoter in COPD and COPD exacerbations |
| Q30426667 | Importance of hedgehog interacting protein and other lung function genes in asthma |
| Q35812803 | Increased Transcript Complexity in Genes Associated with Chronic Obstructive Pulmonary Disease |
| Q28743099 | Individual and cumulative effects of GWAS susceptibility loci in lung cancer: associations after sub-phenotyping for COPD |
| Q40839090 | Inflammatory and Immune Response Genes Polymorphisms are Associated with Susceptibility to Chronic Obstructive Pulmonary Disease in Tatars Population from Russia. |
| Q35868427 | Integrating Multiple Correlated Phenotypes for Genetic Association Analysis by Maximizing Heritability |
| Q59129180 | Integration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module |
| Q48273700 | Integrative Genomics of Emphysema-Associated Genes: Are We Closer to Identifying the Genetic Determinants of Lung Function? |
| Q34232677 | Integrative genomics of chronic obstructive pulmonary disease. |
| Q57011128 | Investigation of novel genes for lung function in children and their interaction with tobacco smoke exposure: a preliminary report |
| Q61805692 | Joint Analysis of Multiple Phenotypes in Association Studies based on Cross-Validation Prediction Error |
| Q90199040 | Joint analysis of multiple phenotypes using a clustering linear combination method based on hierarchical clustering |
| Q36207326 | Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways |
| Q38169066 | Lessons from ECLIPSE: a review of COPD biomarkers |
| Q52651993 | Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations. |
| Q64119446 | Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population |
| Q34535065 | Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease |
| Q35156969 | Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function |
| Q36258075 | Lung Cancer Risk Prediction Using Common SNPs Located in GWAS-Identified Susceptibility Regions |
| Q50184676 | Matrix metalloproteinases in emphysema. |
| Q34331434 | Mechanistic links between COPD and lung cancer |
| Q36274543 | Messenger RNA and MicroRNA transcriptomic signatures of cardiometabolic risk factors |
| Q56992676 | Meta-analysis of exome array data identifies six novel genetic loci for lung function |
| Q36547252 | Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice |
| Q38243943 | Moving beyond genetics: is FAM13A a major biological contributor in lung physiology and chronic lung diseases? |
| Q37175834 | NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. |
| Q26801417 | Natural history of COPD: Focusing on change in FEV1 |
| Q35031894 | Nitric oxide synthase polymorphisms, gene expression and lung function in chronic obstructive pulmonary disease |
| Q36123192 | Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank |
| Q57289193 | Obesity-associated family with sequence similarity 13, member A (FAM13A) is dispensable for adipose development and insulin sensitivity |
| Q33894834 | On the follow-up of genome-wide association studies: an overall test for the most promising SNPs |
| Q37482173 | On the simultaneous association analysis of large genomic regions: a massive multi-locus association test |
| Q34854354 | Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report |
| Q38155607 | Personalizing and targeting therapy for COPD: the role of molecular and clinical biomarkers. |
| Q74441560 | Perspective: How can genetics help? |
| Q38121970 | Pharmacogenetics of chronic obstructive pulmonary disease |
| Q34619853 | Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene |
| Q39226768 | Phenotyping Before Starting Treatment in COPD? |
| Q38063326 | Phenotyping the heterogeneity of chronic obstructive pulmonary disease |
| Q45071140 | Polymorphisms in PDE4D are associated with a risk of COPD in non-emphysematous Koreans |
| Q30826972 | Post-GWAS Prioritization Through Data Integration Provides Novel Insights on Chronic Obstructive Pulmonary Disease. |
| Q64086915 | RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD |
| Q34922245 | Refining susceptibility loci of chronic obstructive pulmonary disease with lung eqtls |
| Q35171019 | Regulation of nuclear-cytoplasmic shuttling and function of Family with sequence similarity 13, member A (Fam13a), by B56-containing PP2As and Akt. |
| Q54484018 | Research Highlights: Pulling out novel COPD genes from the 'gray zone' of genome-wide association studies. |
| Q29416987 | Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis |
| Q38827548 | Risk of Lung Disease in PI MZ Heterozygotes. Current Status and Future Research Directions |
| Q35107672 | SOX5 is a candidate gene for chronic obstructive pulmonary disease susceptibility and is necessary for lung development. |
| Q40472286 | Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women. |
| Q36392496 | Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation |
| Q37549358 | Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2. |
| Q33833861 | Smoking status and gene susceptibility play important roles in the development of chronic obstructive pulmonary disease and lung function decline: A population-based prospective study |
| Q35999518 | Susceptibility loci in lung cancer and COPD: association of IREB2 and FAM13A with pulmonary diseases. |
| Q50417026 | Susceptibility to Childhood Pneumonia: A Genome-Wide Analysis. |
| Q36257364 | Targeted Sequencing of Lung Function Loci in Chronic Obstructive Pulmonary Disease Cases and Controls |
| Q36190156 | Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease |
| Q90499799 | Testing an optimally weighted combination of common and/or rare variants with multiple traits |
| Q42689380 | The Advent of High-Throughput Sequencing Studies of Chronic Obstructive Pulmonary Disease |
| Q35041524 | The MUC5B promoter polymorphism is associated with idiopathic pulmonary fibrosis in a Mexican cohort but is rare among Asian ancestries. |
| Q35684791 | The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility |
| Q47668519 | The effects of CXCL10 polymorphisms on COPD susceptibility |
| Q36833366 | The impact of genetic variation and cigarette smoke on DNA methylation in current and former smokers from the COPDGene study |
| Q42589727 | The role of CFTR mutations in asthma |
| Q35528415 | The state of genome-wide association studies in pulmonary disease: a new perspective |
| Q51764891 | Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. |
| Q92405357 | Two-hybrid screening of FAM13A protein partners in lung epithelial cells |
| Q49026661 | Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics. |
| Q26824935 | Updates on the COPD gene list |
| Q38642884 | Using omics approaches to understand pulmonary diseases |
| Q35813643 | Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function |
| Q35914781 | Variants in multiple genes polymorphism association analysis of COPD in the Chinese Li population |
| Q39049231 | WNT Signaling in Lung Aging and Disease. |
| Q38026994 | What can genetics tell us about the cause of fixed airflow obstruction? |
| Q47801457 | What do polymorphisms tell us about the mechanisms of COPD? |
| Q64059551 | What lies beneath? Molecular evolution during the radiation of caecilian amphibians |
| Q56355677 | Whole Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease |
| Q90636929 | Whole exome sequencing analysis in severe chronic obstructive pulmonary disease |
| Q36443195 | Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility |
| Q37220513 | Whole-exome sequencing reveals genetic variability among lung cancer cases subphenotyped for emphysema |
| Q37845433 | Year-in-review 2010: asthma, COPD, cystic fibrosis and airway biology |
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