COPD is accompanied by co-ordinated transcriptional perturbation in the quadriceps affecting the mitochondria and extracellular matrix

scientific article published in Scientific Reports

COPD is accompanied by co-ordinated transcriptional perturbation in the quadriceps affecting the mitochondria and extracellular matrix is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-018-29789-6
P932PMC publication ID6093887
P698PubMed publication ID30111857

P50authorWilliam CooksonQ56959292
Saffron Willis-OwenQ86177895
P2093author name stringMiriam F Moffatt
Michael I Polkey
Paul R Kemp
Samantha A Natanek
Anna Thompson
P2860cites workA novel technique for nonvolitional assessment of quadriceps muscle endurance in humansQ56508004
Reduced mitochondrial density in the vastus lateralis muscle of patients with COPDQ56508029
High-Dimensional Regression and Variable Selection Using CAR ScoresQ57081835
Roles of histamine in exercise-induced fatigue: favouring endurance and protecting against exhaustionQ83186658
Evidence of a broad histamine footprint on the human exercise transcriptomeQ89151045
WGCNA: an R package for weighted correlation network analysisQ21284194
Pulmonary rehabilitation for chronic obstructive pulmonary diseaseQ24243959
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple TestingQ24570129
Remodelling the extracellular matrix in development and diseaseQ26864798
The role of pannexin hemichannels in inflammation and regenerationQ27500428
Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysisQ29416987
Genome-wide association study of smoking behaviours in patients with COPDQ29417072
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosisQ30274832
Variants in FAM13A are associated with chronic obstructive pulmonary diseaseQ33687879
Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metforminQ34292557
Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary diseaseQ34309196
Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patternsQ34425983
The prevalence of quadriceps weakness in COPD and the relationship with disease severityQ34575095
ITGB5 and AGFG1 variants are associated with severity of airway responsivenessQ34975703
Genome-wide mRNA expression profiling in vastus lateralis of COPD patients with low and normal fat free mass index and healthy controlsQ35097330
IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary diseaseQ35207735
Elevated CO(2) levels cause mitochondrial dysfunction and impair cell proliferationQ35423256
Peripheral muscle endurance and the oxidative profile of the quadriceps in patients with COPDQ35536881
Wnt/β-catenin controls follistatin signalling to regulate satellite cell myogenic potential.Q35575301
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viabilityQ35621293
Extracellular matrix regulation in the muscle satellite cell niche.Q35731463
A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.Q35816887
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Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary DiseaseQ36049194
Genetic variation in antioxidant enzymes and lung functionQ36079234
A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging PhenotypesQ36128611
Muscle fibre type shifting in the vastus lateralis of patients with COPD is associated with disease severity: a systematic review and meta-analysisQ36831910
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Circulating Follistatin Is Liver-Derived and Regulated by the Glucagon-to-Insulin RatioQ38812954
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targetsQ39568339
Re-expression of ABI3-binding protein suppresses thyroid tumor growth by promoting senescence and inhibiting invasionQ39971591
Developmental myosins: expression patterns and functional significanceQ41600339
Abi3bp is a multifunctional autocrine/paracrine factor that regulates mesenchymal stem cell biologyQ41965313
A novel transcript is up-regulated by fasting in the hypothalamus and enhances insulin signalling.Q41979127
Vastus lateralis fiber shift is an independent predictor of mortality in chronic obstructive pulmonary diseaseQ42993162
Midthigh muscle cross-sectional area is a better predictor of mortality than body mass index in patients with chronic obstructive pulmonary diseaseQ44067405
Heterogeneity of quadriceps muscle phenotype in chronic obstructive pulmonary disease (Copd); implications for stratified medicine?Q46210278
A Genome-wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos.Q47639018
Relevance of assessing quadriceps endurance in patients with COPD.Q47946769
Network modules uncover mechanisms of skeletal muscle dysfunction in COPD patients.Q49795543
Alternative splicing of the OCC-1 gene generates three splice variants and a novel exonic microRNA, which regulate the Wnt signaling pathway.Q50223062
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesWGCNAQ102537983
limmaQ112236343
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
chronic obstructive pulmonary diseaseQ199804
extracellular mitochondrionQ107488589
P304page(s)12165
P577publication date2018-08-15
P1433published inScientific ReportsQ2261792
P1476titleCOPD is accompanied by co-ordinated transcriptional perturbation in the quadriceps affecting the mitochondria and extracellular matrix
P478volume8

Reverse relations

cites work (P2860)
Q92374436Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort
Q90216573CYP1B1, VEGFA, BCL2, and CDKN1A Affect the Development of Chronic Obstructive Pulmonary Disease
Q93024600EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype
Q93013804Locomotor Muscles in COPD: The Rationale for Rehabilitative Exercise Training
Q64951257Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing ABI3BP in gallbladder cancer cells.
Q63352656Quadriceps miR-542-3p and 5p are elevated in COPD and reduce function by inhibiting ribosomal and protein synthesis

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