| scholarly article | Q13442814 |
| meta-analysis | Q815382 |
| P50 | author | Mateusz Siedlinski | Q58331270 |
| Xiangyang Kong | Q64481933 | ||
| Ruth Tal-Singer | Q75469591 | ||
| John E Hokanson | Q89513456 | ||
| Emiel F M Wouters | Q89553449 | ||
| Blanca E Himes | Q89725385 | ||
| Barbara J Klanderman | Q114440518 | ||
| William MacNee | Q38326286 | ||
| Jørgen Vestbo | Q41838693 | ||
| Augusto A Litonjua | Q42572197 | ||
| P2093 | author name string | David Sparrow | |
| David A Lomas | |||
| Stephen Rennard | |||
| Christoph Lange | |||
| Wayne H Anderson | |||
| Barry J Make | |||
| Bartolome Celli | |||
| Craig P Hersh | |||
| Edwin K Silverman | |||
| Elizabeth A Regan | |||
| Emily S Wan | |||
| James D Crapo | |||
| Michael H Cho | |||
| Peter J Castaldi | |||
| Terri H Beaty | |||
| Amund Gulsvik | |||
| COPDGene Investigators | |||
| ECLIPSE Investigators | |||
| Per Bakke | |||
| Harvey O Coxson | |||
| Peter M A Calverley | |||
| Jody S Sylvia | |||
| John P Ziniti | |||
| Sreekumar G Pillai | |||
| Jacqueline B Hetmanski | |||
| Courtney Crim | |||
| Alvar Agusti | |||
| Dawn L Demeo | |||
| Tanda Murray | |||
| Julie C Yates | |||
| Lisa D Edwards | |||
| ICGN Investigators | |||
| P2860 | cites work | Population structure and eigenanalysis | Q21145248 |
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| PLINK: a tool set for whole-genome association and population-based linkage analyses | Q24677407 | ||
| Principal components analysis corrects for stratification in genome-wide association studies | Q27860975 | ||
| A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema | Q28205534 | ||
| Common polygenic variation contributes to risk of schizophrenia and bipolar disorder | Q28250609 | ||
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| Global and gene-specific translational regulation in rat lung development | Q28579194 | ||
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| Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease | Q29417023 | ||
| Genome-wide association study of smoking behaviours in patients with COPD | Q29417072 | ||
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| The future of genetic studies of complex human diseases | Q29547215 | ||
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| Case-control studies on risk factors for chronic obstructive pulmonary disease: how does the sampling of the cases and controls affect the results? | Q51816387 | ||
| Exhaustive allelic transmission disequilibrium tests as a new approach to genome-wide association studies. | Q51985806 | ||
| Hypoxia-inducible factors in the first trimester human lung. | Q51998492 | ||
| Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis. | Q52241091 | ||
| Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease. | Q53409072 | ||
| The SERPINE2 gene is associated with chronic obstructive pulmonary disease in two large populations. | Q53572756 | ||
| Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases | Q57233959 | ||
| Genome-wide linkage analysis of bronchodilator responsiveness and post-bronchodilator spirometric phenotypes in chronic obstructive pulmonary disease | Q57253805 | ||
| Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE) | Q57955885 | ||
| Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes | Q71072314 | ||
| The Familial Occurrence of Chronic Obstructive Pulmonary Disease | Q72594592 | ||
| Siblings of patients with severe chronic obstructive pulmonary disease have a significant risk of airflow obstruction | Q77158107 | ||
| Effects of randomized assignment to a smoking cessation intervention and changes in smoking habits on respiratory symptoms in smokers with early chronic obstructive pulmonary disease: the Lung Health Study | Q77391582 | ||
| Does genetic testing result in behavioral health change? Changes in smoking behavior following testing for alpha-1 antitrypsin deficiency | Q79753562 | ||
| Chromosome 4q31 locus in COPD is also associated with lung cancer | Q82674649 | ||
| Variants in FAM13A are associated with chronic obstructive pulmonary disease | Q33687879 | ||
| The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study | Q33820228 | ||
| A novel CYP2A6 allele (CYP2A6*35) resulting in an amino-acid substitution (Asn438Tyr) is associated with lower CYP2A6 activity in vivo | Q34068238 | ||
| Genetic epidemiology of COPD (COPDGene) study design | Q34074731 | ||
| Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior | Q34112069 | ||
| Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study | Q34326181 | ||
| The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial | Q34394365 | ||
| Metabolism and disposition kinetics of nicotine | Q34398241 | ||
| Developing COPD: a 25 year follow up study of the general population | Q34577485 | ||
| Quantitative relationships between cigarette smoking and ventilatory function | Q34730271 | ||
| Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5-A3 genetic locus and lung cancer risk | Q34778144 | ||
| Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report | Q34854354 | ||
| The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans | Q35048184 | ||
| Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies | Q35136958 | ||
| Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine | Q36983085 | ||
| Genetic association analysis of functional impairment in chronic obstructive pulmonary disease | Q37144319 | ||
| Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations | Q37273821 | ||
| A functional mutation in the terminal exon of elastin in severe, early-onset chronic obstructive pulmonary disease | Q37273940 | ||
| Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene | Q37373901 | ||
| Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development | Q37417872 | ||
| Hedgehog-interacting protein is a COPD susceptibility gene: the Rotterdam Study | Q38377093 | ||
| Is calculating pack-years retrospectively a valid method to estimate life-time tobacco smoking? A comparison between prospectively calculated pack-years and retrospectively calculated pack-years | Q40667097 | ||
| PBAT: tools for family-based association studies | Q42930203 | ||
| The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema | Q43223136 | ||
| Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent. | Q43597583 | ||
| Smoking, serum lipids, blood pressure, and sex differences in myocardial infarction. A 12-year follow-up of the Finnmark Study | Q44171249 | ||
| Genetic variation of CYP2A6, smoking, and risk of cancer. | Q44222316 | ||
| The natural history of chronic airflow obstruction revisited: an analysis of the Framingham offspring cohort | Q44934998 | ||
| Lung cancer gene associated with COPD: triple whammy or possible confounding effect? | Q46269161 | ||
| Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC. | Q47125986 | ||
| Genetic susceptibility testing in smoking-cessation treatment: one-year outcomes of a randomized trial. | Q48732906 | ||
| P4510 | describes a project that uses | genome-wide association study | Q1098876 |
| P433 | issue | 4 | |
| P921 | main subject | genome-wide association study | Q1098876 |
| susceptibility locus | Q62091149 | ||
| P304 | page(s) | 947-957 | |
| P577 | publication date | 2011-11-11 | |
| P1433 | published in | Human Molecular Genetics | Q2720965 |
| P1476 | title | A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. | |
| P478 | volume | 21 |
| Q94561716 | A Between Ethnicities Comparison of Chronic Obstructive Pulmonary Disease Genetic Risk |
| Q36128611 | A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes |
| Q36844920 | A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease |
| Q35860362 | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry |
| Q36089387 | A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence |
| Q47564198 | A novel method to test associations between a weighted combination of phenotypes and genetic variants. |
| Q34987218 | Airway basal cells. The "smoking gun" of chronic obstructive pulmonary disease |
| Q47319993 | Airway morphology and inspiratory flow features in the early stages of Chronic Obstructive Pulmonary Disease. |
| Q57909754 | Alpha-1 Antitrypsin PiMZ Genotype Is Associated with Chronic Obstructive Pulmonary Disease in Two Racial Groups |
| Q38066244 | An omics strategy for discovering pulmonary biomarkers potentially relevant to the evaluation of tobacco products |
| Q91582055 | Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene |
| Q48187452 | Association between Genetic Variations of MERTK and Chronic Obstructive Pulmonary Disease in Koreans. |
| Q52599632 | Association of Time to First Morning Cigarette and Chronic Obstructive Pulmonary Disease Measured by Spirometry in Current Smokers. |
| Q51580410 | Association of multiple genetic variants with chronic obstructive pulmonary disease susceptibility in Hainan region. |
| Q37581425 | Association of nsv823469 copy number loss with decreased risk of chronic obstructive pulmonary disease and pulmonary function in Chinese |
| Q40114829 | Beyond GWAS in COPD: probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks |
| Q34840130 | Bridging the clinical gaps: genetic, epigenetic and transcriptomic biomarkers for the early detection of lung cancer in the post-National Lung Screening Trial era |
| Q47676097 | COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression |
| Q58778491 | COPD is accompanied by co-ordinated transcriptional perturbation in the quadriceps affecting the mitochondria and extracellular matrix |
| Q26777324 | Candidate genes for COPD: current evidence and research |
| Q38636068 | Chronic Obstructive Pulmonary Disease Genetics: A Review of the Past and a Look Into the Future |
| Q53186860 | Chronic Obstructive Pulmonary Disease Meta Genome-Wide Association Studies. New Insights into the Genetics of Chronic Obstructive Pulmonary Disease. |
| Q27027955 | Chronic obstructive pulmonary disease |
| Q37731708 | Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema |
| Q34471260 | Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease |
| Q26864326 | Complex genetics of pulmonary diseases: lessons from genome-wide association studies and next-generation sequencing |
| Q33799715 | DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways |
| Q41665058 | DNA methylation profiling in human lung tissue identifies genes associated with COPD. |
| Q57757087 | DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease |
| Q92029835 | DSP variants may be associated with longitudinal change in quantitative emphysema |
| Q37396382 | Differential DNA methylation marks and gene comethylation of COPD in African-Americans with COPD exacerbations |
| Q34418291 | Disease risk factors identified through shared genetic architecture and electronic medical records |
| Q36691602 | Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility. |
| Q30361777 | Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD. |
| Q26865324 | Early events in the pathogenesis of chronic obstructive pulmonary disease. Smoking-induced reprogramming of airway epithelial basal progenitor cells |
| Q34989644 | Elevated serum iron is a potent biomarker for spirometric resistance to cigarette smoke among Japanese males: the Takahata study |
| Q36389310 | Emerging genetics of COPD. |
| Q50044127 | Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary disease. |
| Q40157543 | Epigenome-wide association study of chronic obstructive pulmonary disease and lung function in Koreans |
| Q98772259 | Epithelial cell-specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice |
| Q37125510 | Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease |
| Q37013121 | Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease |
| Q50420061 | Extracellular matrix in lung development, homeostasis and disease. |
| Q51075726 | Extracellular matrix remodeling genes polymorphisms and risk of chronic bronchitis and recurrent pneumonia in children. |
| Q38757264 | Extreme Trait Whole-Genome Sequencing Identifies PTPRO as a Novel Candidate Gene in Emphysema with Severe Airflow Obstruction. |
| Q37695214 | Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue |
| Q36862051 | Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells |
| Q38974166 | Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects. |
| Q47171958 | Genetic Pleiotropy between Nicotine Dependence and Respiratory Outcomes |
| Q37166853 | Genetic association between human chitinases and lung function in COPD |
| Q36724956 | Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci |
| Q30274832 | Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis |
| Q36229721 | Genetic polymorphism of heme oxygenase 1 promoter in the occurrence and severity of chronic obstructive pulmonary disease: a meta-analysis |
| Q34342451 | Genetic polymorphisms and associated susceptibility to asthma |
| Q51700279 | Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction. |
| Q100526128 | Genetic regulation of gene expression of MIF family members in lung tissue |
| Q45074419 | Genetic studies as a tool for identifying novel potential targets for treatment of COPD. |
| Q34309196 | Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease |
| Q24606717 | Genetic susceptibility to lung cancer and co-morbidities |
| Q90211681 | Genetic underpinnings of lung function and COPD |
| Q34847876 | Genetic variation in HTR4 and lung function: GWAS follow-up in mouse |
| Q89454591 | Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development |
| Q29416995 | Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease |
| Q34425983 | Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns |
| Q30420166 | Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction |
| Q30408059 | Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study |
| Q88324448 | Genotype imputation performance of three reference panels using African ancestry individuals |
| Q36155424 | Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study |
| Q37304387 | Heritability of chronic obstructive pulmonary disease and related phenotypes in smokers |
| Q35207735 | IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease |
| Q86573040 | Identification of FAM13A gene associated with the ratio of FEV1 to FVC in Korean population by genome-wide association studies including gene-environment interactions |
| Q36372888 | Identifying a Deletion Affecting Total Lung Capacity Among Subjects in the COPDGene Study Cohort |
| Q59129180 | Integration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module |
| Q48273700 | Integrative Genomics of Emphysema-Associated Genes: Are We Closer to Identifying the Genetic Determinants of Lung Function? |
| Q30883307 | Integrative analysis of DNA methylation and gene expression data identifies EPAS1 as a key regulator of COPD. |
| Q52642397 | Integrative genomics identifies new genes associated with severe COPD and emphysema. |
| Q34232677 | Integrative genomics of chronic obstructive pulmonary disease. |
| Q37334535 | Integrative omics approach identifies interleukin-16 as a biomarker of emphysema |
| Q38169066 | Lessons from ECLIPSE: a review of COPD biomarkers |
| Q52651993 | Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations. |
| Q64119446 | Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population |
| Q90383985 | Low miR-150-5p and miR-320b Expression Predicts Reduced Survival of COPD Patients |
| Q50184676 | Matrix metalloproteinases in emphysema. |
| Q36547252 | Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice |
| Q38243943 | Moving beyond genetics: is FAM13A a major biological contributor in lung physiology and chronic lung diseases? |
| Q91908132 | New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries |
| Q41060193 | Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain |
| Q64109060 | Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes |
| Q37482173 | On the simultaneous association analysis of large genomic regions: a massive multi-locus association test |
| Q37654985 | One thousand genomes imputation in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium aggressive prostate cancer genome-wide association study |
| Q74441560 | Perspective: How can genetics help? |
| Q38169240 | Phenotypes and disease characterization in chronic obstructive pulmonary disease. Toward the extinction of phenotypes? |
| Q34619853 | Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene |
| Q39226768 | Phenotyping Before Starting Treatment in COPD? |
| Q38063326 | Phenotyping the heterogeneity of chronic obstructive pulmonary disease |
| Q30826972 | Post-GWAS Prioritization Through Data Integration Provides Novel Insights on Chronic Obstructive Pulmonary Disease. |
| Q34400233 | Protection genes in nucleus accumbens shell affect vulnerability to nicotine self-administration across isogenic strains of adolescent rat |
| Q64086915 | RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD |
| Q34922245 | Refining susceptibility loci of chronic obstructive pulmonary disease with lung eqtls |
| Q37176968 | Relationship between plasma fibrinogen levels and pulmonary function in the japanese population: the Takahata study |
| Q37629306 | Reprogramming of COPD lung fibroblasts through formation of induced pluripotent stem cells |
| Q54257597 | Research Highlights: Highlights from the latest articles in chronic obstructive pulmonary disease genetics. |
| Q29416987 | Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis |
| Q23910387 | Role of genetic factors in pulmonary disease susceptibility |
| Q28387428 | SERPINA1 PiZ and PiS heterozygotes and lung function decline in the SAPALDIA cohort |
| Q36310868 | Screening for interaction effects in gene expression data |
| Q40472286 | Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women. |
| Q36392496 | Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation |
| Q37549358 | Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2. |
| Q33833861 | Smoking status and gene susceptibility play important roles in the development of chronic obstructive pulmonary disease and lung function decline: A population-based prospective study |
| Q35143045 | Susceptibility to chronic mucus hypersecretion, a genome wide association study |
| Q41679073 | The Functional Copy Number Variation-67048 in WWOX Contributes to Increased Risk of COPD in Southern and Eastern Chinese |
| Q38239649 | The IRP/IRE system in vivo: insights from mouse models |
| Q50050250 | The PHD1 oxygen sensor in health and disease. |
| Q37573962 | The contribution of common UGT2B10 and CYP2A6 alleles to variation in nicotine glucuronidation among European Americans |
| Q34834259 | The effects of Gamijinhae-tang on elastase/lipopolysaccharide-induced lung inflammation in an animal model of acute lung injury |
| Q36605892 | The role of WWOX polymorphisms on COPD susceptibility and pulmonary function traits in Chinese: a case-control study and family-based analysis |
| Q51559655 | Time to First Cigarette, a Proxy of Nicotine Dependence, Increases the Risk of Pulmonary Impairment, Independently of Current and Lifetime Smoking Behavior. |
| Q104257661 | Transferability Of Ancestry-Specific And Cross-Ancestry CYP2A6 Activity Genetic Risk Scores In African And European Populations |
| Q26824935 | Updates on the COPD gene list |
| Q38215807 | Using pulmonary imaging to move chronic obstructive pulmonary disease beyond FEV1. |
| Q35914781 | Variants in multiple genes polymorphism association analysis of COPD in the Chinese Li population |
| Q37406432 | Variants in two adjacent genes, EGLN2 and CYP2A6, influence smoking behavior related to disease risk via different mechanisms |
| Q37690237 | Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction. |
| Q47801457 | What do polymorphisms tell us about the mechanisms of COPD? |
| Q56355677 | Whole Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease |
| Q36443195 | Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility |
| Q100558998 | Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants |
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