Exon sequencing identifies a novel CHRNA3-CHRNA5-CHRNB4 variant that increases the risk for chronic obstructive pulmonary disease.

scientific article published on 19 April 2015

Exon sequencing identifies a novel CHRNA3-CHRNA5-CHRNB4 variant that increases the risk for chronic obstructive pulmonary disease. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/RESP.12539
P698PubMed publication ID25891420
P5875ResearchGate publication ID275216060

P2093author name stringFang He
Hua He
Bing Li
Fang Peng
Pixin Ran
Weifeng Zou
Yumin Zhou
Zhuxiang Zhao
Guoping Hu
Ziwen Zhao
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Standardisation of spirometryQ29547365
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A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.Q33419815
Variants in FAM13A are associated with chronic obstructive pulmonary diseaseQ33687879
Genetic variation in antioxidant enzymes, cigarette smoking, and longitudinal change in lung functionQ33765854
Four SNPs in the CHRNA3/5 alpha-neuronal nicotinic acetylcholine receptor subunit locus are associated with COPD risk based on meta-analysesQ33933180
Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in ChineseQ34441086
Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary diseaseQ34535065
Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell linesQ34849133
Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependenceQ34850154
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Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence.Q35674705
CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in PolandQ36176931
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPsQ36501908
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Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.Q37272338
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Lung cancer gene associated with COPD: triple whammy or possible confounding effect?Q46269161
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The long internal loop of the alpha 3 subunit targets nAChRs to subdomains within individual synapses on neurons in vivo.Q48921095
Genetic association between COPD and polymorphisms in TNF, ADRB2 and EPHX1.Q51944698
Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.Q52299798
P433issue5
P921main subjectchronic obstructive pulmonary diseaseQ199804
P304page(s)790-798
P577publication date2015-04-19
P1433published inRespirologyQ15753093
P1476titleExon sequencing identifies a novel CHRNA3-CHRNA5-CHRNB4 variant that increases the risk for chronic obstructive pulmonary disease.
P478volume20

Reverse relations

cites work (P2860)
Q39555227An efficient method to genotype the polymorphisms of cholinergic nicotinic receptor subunit genes and their associations with COPD onset risk
Q47171958Genetic Pleiotropy between Nicotine Dependence and Respiratory Outcomes
Q39000705Rare variant of MAP2K7 is associated with increased risk of COPD in southern and eastern Chinese
Q33713727Two CHRN susceptibility variants for COPD are genetic determinants of emphysema and chest computed tomography manifestations in Chinese patients
Q51485232UBXN2A regulates nicotinic receptor degradation by modulating the E3 ligase activity of CHIP.
Q26749314Year in review 2015: Asthma and chronic obstructive pulmonary disease

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