Chromosome Missegregation Associated with RUVBL1 Deficiency

scientific article published on 22 July 2015

Chromosome Missegregation Associated with RUVBL1 Deficiency is …
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P819ADS bibcode2015PLoSO..1033576G
P356DOI10.1371/JOURNAL.PONE.0133576
P8608Fatcat IDrelease_6oaa4d2dlrbyrbpnl3ntihkb7i
P932PMC publication ID4511761
P698PubMed publication ID26201077
P5875ResearchGate publication ID281820478

P2093author name stringDaniel W Gerlich
Josef Jiricny
Stefano Ferrari
Svenja Kaden
Dennis Castor
Mario Gysi
Patrick Steigemann
Christian Gentili
David Lauterbach
P2860cites workTIP49b, a new RuvB-like DNA helicase, is included in a complex together with another RuvB-like DNA helicase, TIP49aQ22253154
Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosisQ24290159
Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms.Q24294556
AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decayQ24306010
Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assemblyQ24313436
Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agentsQ24337605
A mammalian chromatin remodeling complex with similarities to the yeast INO80 complexQ24338490
Midbody assembly and its regulation during cytokinesisQ24617092
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organizationQ24655829
Substrate recognition and function of the R2TP complex in response to cellular stressQ26824496
Structural and functional insights into a dodecameric molecular machine - the RuvBL1/RuvBL2 complexQ27674330
Structural basis for dodecameric assembly states and conformational plasticity of the full-length AAA+ ATPases Rvb1 · Rvb2Q27697920
Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose platesQ27860715
Yeast Rvb1 and Rvb2 are ATP-dependent DNA helicases that form a heterohexameric complex.Q27933090
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2Q28277364
A rat RuvB-like protein, TIP49a, is a germ cell-enriched novel DNA helicaseQ28565902
RecQ helicases: caretakers of the genomeQ29618390
The emergence of the conserved AAA+ ATPases Pontin and Reptin on the signaling landscapeQ30410169
RVB1/RVB2: running rings around molecular biologyQ30435879
Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexesQ30438402
Kinetic framework of spindle assembly checkpoint signallingQ30581433
Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinaseQ31070565
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammalsQ33327076
RuvB-like ATPases function in chromatin decondensation at the end of mitosis.Q50620440
Relocalization of human chromatin remodeling cofactor TIP48 in mitosis.Q52039618
Increased pontin expression in human colorectal cancer tissue.Q53334413
An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-MycQ33908306
Adenosine triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin through a new posttranslational mechanismQ34080748
First identification of small-molecule inhibitors of Pontin by combining virtual screening and enzymatic assayQ34138135
Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate.Q34195806
PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolutionQ34199248
Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repairQ34472034
An eukaryotic RuvB-like protein (RUVBL1) essential for growthQ34475380
Dodecameric structure and ATPase activity of the human TIP48/TIP49 complexQ34589231
PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpointQ34600951
Methylation-induced G2/M arrest requires a full complement of the mismatch repair protein hMLH1Q35019055
TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolutionQ35218132
Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cellsQ36360359
Protein kinases controlling the onset of mitosis.Q36390394
Probabilistic assembly of human protein interaction networks from label-free quantitative proteomicsQ36446314
Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase PontinQ36739922
Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cellsQ37254703
Boveri revisited: chromosomal instability, aneuploidy and tumorigenesisQ37527786
Mitosis in vertebrates: the G2/M and M/A transitions and their associated checkpointsQ37824833
Crystal structure of the human AAA+ protein RuvBL1.Q38308257
Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPasesQ38937471
The ATPase activity of reptin is required for its effects on tumor cell growth and viability in hepatocellular carcinomaQ39227448
In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in xenografts and is associated with replicative senescenceQ39722171
Overexpression and role of the ATPase and putative DNA helicase RuvB-like 2 in human hepatocellular carcinomaQ40101677
Aurora-A site specificity: a study with synthetic peptide substratesQ40388031
High doses of SN1 type methylating agents activate DNA damage signaling cascades that are largely independent of mismatch repair.Q40463276
Automatic real-time three-dimensional cell tracking by fluorescence microscopy.Q40498221
Mechanisms of helicase-catalyzed DNA unwindingQ41114786
Pontin is essential for murine hematopoietic stem cell survivalQ42323678
BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridgesQ42431691
Aurora B-mediated abscission checkpoint protects against tetraploidizationQ42810739
The ATP‐dependent helicase RUVBL1/TIP49a associates with tubulin during mitosisQ44594490
Mismatch recognition and DNA-dependent stimulation of the ATPase activity of hMutSalpha is abolished by a single mutation in the hMSH6 subunitQ50335571
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)e0133576
P577publication date2015-07-22
P1433published inPLOS OneQ564954
P1476titleChromosome Missegregation Associated with RUVBL1 Deficiency
P478volume10