| P50 | author | Zuzana Hořejší | Q56513640 |
| | Patrick von Morgen | Q63385845 |
| | Libor Macůrek | Q77898702 |
| P2093 | author name string | Libor Macurek | |
| | Zuzana Hořejší | |
| P2860 | cites work | MDM2 binding induces a conformational change in p53 that is opposed by heat-shock protein 90 and precedes p53 proteasomal degradation | Q79960777 |
| | HSP90 and the R2TP co-chaperone complex: building multi-protein machineries essential for cell growth and gene expression | Q83653688 |
| | TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes | Q24295574 |
| | A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability | Q24298271 |
| | APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks | Q24299831 |
| | Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton | Q24299873 |
| | CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability | Q24300796 |
| | mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery | Q24302549 |
| | Tel2 regulates the stability of PI3K-related protein kinases | Q24304948 |
| | AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay | Q24306010 |
| | Human PIH1 associates with histone H4 to mediate the glucose-dependent enhancement of pre-rRNA synthesis | Q24306345 |
| | SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma | Q24306820 |
| | DYX1C1 is required for axonemal dynein assembly and ciliary motility | Q24310331 |
| | Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 | Q24311891 |
| | Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly | Q24313436 |
| | SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs | Q24317979 |
| | Kinase CK2 inhibition: an update. | Q38064928 |
| | Chemical proteomics and functional proteomics strategies for protein kinase inhibitor validation and protein kinase substrate identification: applications to protein kinase CK2. | Q38082285 |
| | Chaperone-like activity of the AAA+ proteins Rvb1 and Rvb2 in the assembly of various complexes | Q38093164 |
| | Heat shock protein 90 inhibitors in non-small-cell lung cancer | Q38181881 |
| | Crystal structure of the human AAA+ protein RuvBL1. | Q38308257 |
| | Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPases | Q38937471 |
| | Protein kinase CK2 is required for the recruitment of 53BP1 to sites of DNA double-strand break induced by radiomimetic drugs. | Q39043983 |
| | The ATPase activity of reptin is required for its effects on tumor cell growth and viability in hepatocellular carcinoma | Q39227448 |
| | A role for chromatin remodellers in replication of damaged DNA. | Q39341270 |
| | Expression and therapeutic relevance of heat-shock protein 90 in pancreatic endocrine tumors | Q39423485 |
| | HSP90 and its R2TP/Prefoldin-like cochaperone are involved in the cytoplasmic assembly of RNA polymerase II | Q39652251 |
| | The human orthologue of Drosophila ecdysoneless protein interacts with p53 and regulates its function | Q40254022 |
| | The Pih1-Tah1 cochaperone complex inhibits Hsp90 molecular chaperone ATPase activity. | Q42005667 |
| | Nutritional status modulates box C/D snoRNP biogenesis by regulated subcellular relocalization of the R2TP complex | Q42040520 |
| | The stability of the small nucleolar ribonucleoprotein (snoRNP) assembly protein Pih1 in Saccharomyces cerevisiae is modulated by its C terminus | Q42180604 |
| | Oligomeric assembly and interactions within the human RuvB-like RuvBL1 and RuvBL2 complexes | Q43089036 |
| | HCLK2 is required for activity of the DNA damage response kinase ATR. | Q45214462 |
| | (1)H, (15)N and (13)C resonance assignments of the two TPR domains from the human RPAP3 protein. | Q45713198 |
| | Hsp90 inhibition enhances PI-3 kinase inhibition and radiosensitivity in glioblastoma. | Q51754497 |
| | Molecular cloning of novel Monad binding protein containing tetratricopeptide repeat domains | Q24319859 |
| | A dynamic scaffold of pre-snoRNP factors facilitates human box C/D snoRNP assembly | Q24320399 |
| | Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins | Q24321284 |
| | Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme | Q24321455 |
| | The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins | Q24328753 |
| | PIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcription | Q24336209 |
| | Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage | Q24336328 |
| | Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex | Q24339507 |
| | The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc | Q24554343 |
| | A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus | Q24652236 |
| | DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics | Q24681614 |
| | Chaperone machines for protein folding, unfolding and disaggregation | Q27026110 |
| | Structural and functional insights into a dodecameric molecular machine - the RuvBL1/RuvBL2 complex | Q27674330 |
| | Large-scale conformational flexibility determines the properties of AAA+ TIP49 ATPases | Q27681647 |
| | Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1 | Q27683635 |
| | High-resolution structural analysis shows how Tah1 tethers Hsp90 to the R2TP complex | Q27685466 |
| | Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone | Q27740876 |
| | Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III | Q27747193 |
| | TOR signaling in growth and metabolism | Q27860757 |
| | Chaperone ligand-discrimination by the TPR-domain protein Tah1. | Q27929748 |
| | Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation | Q27929861 |
| | The prefoldin bud27 mediates the assembly of the eukaryotic RNA polymerases in an rpb5-dependent manner. | Q27929893 |
| | Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone | Q27930871 |
| | Involvement of actin-related proteins in ATP-dependent chromatin remodeling. | Q27932041 |
| | Yeast Rvb1 and Rvb2 are ATP-dependent DNA helicases that form a heterohexameric complex. | Q27933090 |
| | RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits | Q27934170 |
| | A well-connected and conserved nucleoplasmic helicase is required for production of box C/D and H/ACA snoRNAs and localization of snoRNP proteins. | Q27935012 |
| | Characterization of Saccharomyces cerevisiae Nop17p, a novel Nop58p-interacting protein that is involved in Pre-rRNA processing. | Q27936232 |
| | The ATM-related cofactor Tra1 is a component of the purified SAGA complex | Q27937594 |
| | Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complex | Q27938536 |
| | The Shq1p.Naf1p complex is required for box H/ACA small nucleolar ribonucleoprotein particle biogenesis | Q27939326 |
| | High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes | Q35822226 |
| | Tetratricopeptide repeat cochaperones in steroid receptor complexes | Q35924587 |
| | Mechanism of the AAA+ ATPases pontin and reptin in the biogenesis of H/ACA RNPs | Q36246620 |
| | Sick chaperones, cellular stress, and disease | Q36278493 |
| | The role of SMG-1 in nonsense-mediated mRNA decay. | Q36313711 |
| | The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery | Q36446601 |
| | Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex. | Q36532572 |
| | Control of transcription by Pontin and Reptin | Q36744369 |
| | ATR signalling: more than meeting at the fork | Q36918246 |
| | Pontin and reptin, two related ATPases with multiple roles in cancer. | Q37256105 |
| | Evidence that the AAA+ proteins TIP48 and TIP49 bridge interactions between 15.5K and the related NOP56 and NOP58 proteins during box C/D snoRNP biogenesis. | Q37334036 |
| | Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases | Q37544152 |
| | Drosophila Spag is the homolog of RNA polymerase II-associated protein 3 (RPAP3) and recruits the heat shock proteins 70 and 90 (Hsp70 and Hsp90) during the assembly of cellular machineries | Q37608575 |
| | Rvb1-Rvb2: essential ATP-dependent helicases for critical complexes. | Q37687097 |
| | The multifaceted proteins Reptin and Pontin as major players in cancer | Q37812787 |
| | The R2TP complex: discovery and functions | Q37933871 |
| | ATM and the molecular pathogenesis of ataxia telangiectasia | Q37950453 |
| | Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2. | Q38005990 |
| | Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs | Q27939349 |
| | AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes | Q28131706 |
| | The DNA damage response: putting checkpoints in perspective | Q28131713 |
| | The Hsp90 chaperone machinery: conformational dynamics and regulation by co-chaperones | Q28249196 |
| | A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM | Q28270543 |
| | Structure of eukaryotic RNA polymerases | Q28284822 |
| | Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks | Q28286203 |
| | Enhanced phosphorylation of p53 by ATM in response to DNA damage | Q28609838 |
| | Live or let die: the cell's response to p53 | Q29547663 |
| | DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis | Q29614217 |
| | Sno storm in the nucleolus: new roles for myriad small RNPs | Q29616484 |
| | Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex | Q29617515 |
| | PI3K and cancer: lessons, challenges and opportunities | Q30080017 |
| | The emergence of the conserved AAA+ ATPases Pontin and Reptin on the signaling landscape | Q30410169 |
| | RVB1/RVB2: running rings around molecular biology | Q30435879 |
| | Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes | Q30438402 |
| | Conformational transitions regulate the exposure of a DNA-binding domain in the RuvBL1-RuvBL2 complex | Q30528824 |
| | The AAA team: related ATPases with diverse functions | Q32042429 |
| | A high-throughput, cell-based screening method for siRNA and small molecule inhibitors of mTORC1 signaling using the In Cell Western technique | Q33525149 |
| | Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2 | Q33570316 |
| | Proteasomes and their associated ATPases: a destructive combination | Q33998676 |
| | Emergence of protein kinase CK2 as a key target in cancer therapy | Q34046848 |
| | First identification of small-molecule inhibitors of Pontin by combining virtual screening and enzymatic assay | Q34138135 |
| | Transient interaction of Hsp90 with early unfolding intermediates of citrate synthase. Implications for heat shock in vivo | Q34307813 |
| | DNA binding properties of the actin-related protein Arp8 and its role in DNA repair | Q34315199 |
| | Box C/D snoRNA-associated proteins: two pairs of evolutionarily ancient proteins and possible links to replication and transcription | Q34362725 |
| | Heat shock proteins in cancer: chaperones of tumorigenesis | Q34495261 |
| | Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control | Q34566711 |
| | Dodecameric structure and ATPase activity of the human TIP48/TIP49 complex | Q34589231 |
| | Orchestration of chromatin-based processes: mind the TRRAP. | Q34662254 |
| | Hsp90 molecular chaperone inhibitors: are we there yet? | Q35655105 |
| | Conserved arginine residues implicated in ATP hydrolysis, nucleotide-sensing, and inter-subunit interactions in AAA and AAA+ ATPases. | Q35750529 |
| | Plk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair | Q35759514 |
| | New insights into the biogenesis of nuclear RNA polymerases? | Q35822220 |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 69 | |
| P577 | publication date | 2015-02-25 | |
| P1433 | published in | Frontiers in Genetics | Q2499875 |
| P1476 | title | Substrate recognition and function of the R2TP complex in response to cellular stress | |
| P478 | volume | 6 | |