scholarly article | Q13442814 |
P819 | ADS bibcode | 2015PLoSO..1033391G |
P356 | DOI | 10.1371/JOURNAL.PONE.0133391 |
P932 | PMC publication ID | 4514882 |
P698 | PubMed publication ID | 26208095 |
P5875 | ResearchGate publication ID | 281823356 |
P50 | author | C Michael Hart | Q92643656 |
P2093 | author name string | David E Green | |
Bum-Yong Kang | |||
Charles D Searles | |||
Tamara C Murphy | |||
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Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies | Q33849207 | ||
Hypoxia mediates mutual repression between microRNA-27a and PPARγ in the pulmonary vasculature | Q42593185 | ||
Rosiglitazone attenuates hypoxia-induced pulmonary arterial hypertension in rats | Q43024791 | ||
MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity | Q43083934 | ||
Peroxisome proliferator-activated receptor gamma depletion stimulates Nox4 expression and human pulmonary artery smooth muscle cell proliferation | Q43182141 | ||
Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN. | Q43621579 | ||
Effects of peroxisome proliferator-activated receptor gamma ligands on monocrotaline-induced pulmonary hypertension in rats | Q46558968 | ||
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Pulmonary arterial hypertension is linked to insulin resistance and reversed by peroxisome proliferator-activated receptor-gamma activation. | Q51763432 | ||
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Peroxisome Proliferator-Activated Receptor-γ Ameliorates Pulmonary Arterial Hypertension by Inhibiting 5-Hydroxytryptamine 2B Receptor | Q58335888 | ||
A Role for miR-145 in Pulmonary Arterial Hypertension | Q63916426 | ||
Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling | Q79451455 | ||
microRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma | Q84623574 | ||
miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis | Q34044475 | ||
PPAR{gamma} regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-{kappa}B. | Q34212735 | ||
BMP-2 up-regulates PTEN expression and induces apoptosis of pulmonary artery smooth muscle cells under hypoxia | Q34277172 | ||
The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation | Q34294854 | ||
MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migration | Q34426103 | ||
miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression | Q34528510 | ||
An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension | Q34589929 | ||
Role for miR-204 in human pulmonary arterial hypertension | Q34681312 | ||
Is peroxisome proliferator-activated receptor gamma (PPARγ) a therapeutic target for the treatment of pulmonary hypertension? | Q34897476 | ||
The microRNA-130/301 family controls vasoconstriction in pulmonary hypertension | Q35002833 | ||
Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation | Q35085751 | ||
Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival | Q35187029 | ||
MicroRNAs in pulmonary arterial hypertension | Q35207669 | ||
Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling | Q35601455 | ||
miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling. | Q35850316 | ||
The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study | Q36001145 | ||
Peroxisome proliferator-activated receptor gamma (PPARγ) regulates thrombospondin-1 and Nox4 expression in hypoxia-induced human pulmonary artery smooth muscle cell proliferation | Q36563581 | ||
MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4. | Q36673482 | ||
Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology | Q36701812 | ||
Molecular pathogenesis of pulmonary arterial hypertension | Q36736065 | ||
New insights into PTEN. | Q37011116 | ||
Understanding PTEN regulation: PIP2, polarity and protein stability | Q37270444 | ||
PPARgamma as a potential therapeutic target in pulmonary hypertension | Q37689190 | ||
PPARgamma and the pathobiology of pulmonary arterial hypertension | Q37702992 | ||
Emerging therapies for the treatment of pulmonary hypertension | Q37705888 | ||
miRNAs: roles and clinical applications in vascular disease | Q37822463 | ||
Hypoxia downregulates PPARγ via an ERK1/2-NF-κB-Nox4-dependent mechanism in human pulmonary artery smooth muscle cells | Q39150404 | ||
MicroRNAs-control of essential genes: Implications for pulmonary vascular disease. | Q39385085 | ||
Peroxisome proliferator-activated receptor γ agonist troglitazone inhibits high mobility group box 1 expression in endothelial cells via suppressing transcriptional activity of nuclear factor κB and activator protein 1. | Q39535578 | ||
The PPARγ ligand rosiglitazone attenuates hypoxia-induced endothelin signaling in vitro and in vivo | Q39684983 | ||
Rosiglitazone attenuates chronic hypoxia-induced pulmonary hypertension in a mouse model | Q39879690 | ||
Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension | Q40036197 | ||
Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Expression Is Decreased in Pulmonary Hypertension and Affects Endothelial Cell Growth | Q40652271 | ||
MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation | Q41166615 | ||
Dysregulation of PTEN in cardiopulmonary vascular remodeling induced by pulmonary hypertension. | Q41170725 | ||
Holding our breath: The emerging and anticipated roles of microRNA in pulmonary hypertension | Q41546903 | ||
Selective inactivation of PTEN in smooth muscle cells synergizes with hypoxia to induce severe pulmonary hypertension | Q41827194 | ||
MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach | Q42172409 | ||
P275 | copyright license | Creative Commons CC0 License | Q6938433 |
P6216 | copyright status | copyrighted, dedicated to the public domain by copyright holder | Q88088423 |
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | hypoxia | Q105688 |
microRNA | Q310899 | ||
Phosphatase and tensin homolog | Q416356 | ||
negative regulation of vascular associated smooth muscle cell proliferation | Q22304651 | ||
P304 | page(s) | e0133391 | |
P577 | publication date | 2015-07-24 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | PPARγ Ligands Attenuate Hypoxia-Induced Proliferation in Human Pulmonary Artery Smooth Muscle Cells through Modulation of MicroRNA-21. | |
P478 | volume | 10 |