scholarly article | Q13442814 |
P50 | author | Jan H Beumer | Q49531403 |
P2093 | author name string | Hussein Tawbi | |
Christopher J Bakkenist | |||
John C Schmitz | |||
R Kenneth Czambel | |||
Pamela A Hershberger | |||
P2860 | cites work | Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay | Q24291647 |
The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells | Q24294881 | ||
Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks | Q24651854 | ||
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers | Q27851474 | ||
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase | Q28131711 | ||
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 | Q28131715 | ||
Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139 | Q28139691 | ||
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays | Q28145712 | ||
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation | Q28206029 | ||
The ATR-p53 pathway is suppressed in noncycling normal and malignant lymphocytes | Q28241779 | ||
Modeling pharmacodynamic response to the poly(ADP-Ribose) polymerase inhibitor ABT-888 in human peripheral blood mononuclear cells | Q28477427 | ||
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM | Q29614843 | ||
Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries | Q31128646 | ||
Phase I trial of cremophor EL with bolus doxorubicin. | Q31985007 | ||
Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitors | Q34334481 | ||
ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling | Q34653133 | ||
Histone H2AX in DNA damage and repair. | Q35184065 | ||
Targeting the DNA repair defect of BRCA tumours | Q36162913 | ||
A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations. | Q36908567 | ||
Fit-for-purpose biomarker method validation for application in clinical trials of anticancer drugs | Q37798159 | ||
Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species | Q38335343 | ||
The ATM kinase signaling induced by the low-energy β-particles emitted by (33)P is essential for the suppression of chromosome aberrations and is greater than that induced by the energetic β-particles emitted by (32)P. | Q38583761 | ||
Radiation therapy induces the DNA damage response in peripheral blood | Q39117815 | ||
Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR. | Q39559122 | ||
Irreversible chromosome damage accumulates rapidly in the absence of ATM kinase activity | Q39991232 | ||
Development of pharmacodynamic biomarkers for ATR inhibitors. | Q41135683 | ||
Discovery of 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole (AZ20): a potent and selective inhibitor of ATR protein kinase with monotherapy in vivo antitumor activity | Q42713005 | ||
Promotion of DNA repair by nuclear IKKβ phosphorylation of ATM in response to genotoxic stimuli | Q44270673 | ||
Phase I and pharmacokinetic study of intravenous irinotecan plus oral ciclosporin in patients with fuorouracil-refractory metastatic colon cancer. | Q44362128 | ||
Simultaneous determination of gemcitabine and its main metabolite, dFdU, in plasma of patients with advanced non-small-cell lung cancer by high-performance liquid chromatography-tandem mass spectrometry | Q46946669 | ||
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. 1979. | Q49012176 | ||
Pharmacokinetic comparison of oral and intravenous etoposide in patients treated with the CHOEP-regimen for malignant lymphomas. | Q51749692 | ||
Near-infrared fluorescence detection permits accurate imaging of loading controls for Western blot analysis | Q80416832 | ||
[Application of two-color infrared fluorescence for detection of protein phosphorylation] | Q82669749 | ||
A comparison of methods for the analysis of low abundance proteins in desmoid tumor cells | Q83858017 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 542-554 | |
P577 | publication date | 2015-05-14 | |
P1433 | published in | Oncoscience | Q27725796 |
P1476 | title | A quasi-quantitative dual multiplexed immunoblot method to simultaneously analyze ATM and H2AX Phosphorylation in human peripheral blood mononuclear cells | |
P478 | volume | 2 |
Q42570959 | ATM serine-1981 phosphorylation is a plausible biomarker |
Q91824813 | Antibody validation for Western blot: By the user, for the user |
Q52655311 | LMTK3 confers chemo-resistance in breast cancer. |
Q47100777 | Phase I study of veliparib in combination with gemcitabine |
Q38796786 | The downregulation of the RNA-binding protein Staufen2 in response to DNA damage promotes apoptosis |
Q58615653 | pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry |
Search more.