scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1044855855 |
P356 | DOI | 10.1038/ONC.2012.192 |
P698 | PubMed publication ID | 22614018 |
P2093 | author name string | R Takahashi | |
Y Hayakawa | |||
S Maeda | |||
Y Hirata | |||
K Sakamoto | |||
H Nakagawa | |||
H Kinoshita | |||
H Kamata | |||
K Sakitani | |||
M Akanuma | |||
W Nakata | |||
Y Hikiba | |||
P2860 | cites work | NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling | Q24298750 |
Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress | Q24300945 | ||
Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair | Q24310231 | ||
A single ataxia telangiectasia gene with a product similar to PI-3 kinase | Q24323579 | ||
The DNA-damage response in human biology and disease | Q24606586 | ||
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells | Q24650179 | ||
The DNA damage response: putting checkpoints in perspective | Q28131713 | ||
Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing | Q28140019 | ||
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation | Q28206029 | ||
Cell-cycle checkpoints and cancer | Q28293996 | ||
Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice | Q28593143 | ||
ATM and related protein kinases: safeguarding genome integrity | Q29547735 | ||
Missing pieces in the NF-kappaB puzzle | Q29547864 | ||
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer | Q29614599 | ||
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion | Q30434675 | ||
ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks | Q31677626 | ||
Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo | Q33388649 | ||
Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites | Q33589782 | ||
ATM: a mediator of multiple responses to genotoxic stress | Q33771767 | ||
How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex | Q33797139 | ||
IKKβ regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells | Q33872159 | ||
ATM Activation by Oxidative Stress | Q34145092 | ||
IKK and NF-kappaB-mediated regulation of Claspin impacts on ATR checkpoint function | Q34148484 | ||
ATM promotes apoptosis and suppresses tumorigenesis in response to Myc. | Q34298505 | ||
ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic Stress | Q34620780 | ||
Involvement of novel autophosphorylation sites in ATM activation | Q34972885 | ||
Nuclear initiated NF-κB signaling: NEMO and ATM take center stage | Q35347865 | ||
KinasePhos 2.0: a web server for identifying protein kinase-specific phosphorylation sites based on sequences and coupling patterns | Q35914240 | ||
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis | Q36368249 | ||
Inflammation and cancer: role of nuclear factor-kappaB activation | Q37092305 | ||
Activation of ATM depends on chromatin interactions occurring before induction of DNA damage | Q37280637 | ||
Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species | Q38335343 | ||
HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents | Q39588354 | ||
Nuclear IKKβ Is an Adaptor Protein for IκBα Ubiquitination and Degradation in UV-Induced NF-κB Activation | Q39662942 | ||
Inhibitor of kappaB kinase beta regulates gastric carcinogenesis via interleukin-1alpha expression. | Q39721819 | ||
3-Nitrobenzanthrone and 3-aminobenzanthrone induce DNA damage and cell signalling in Hepa1c1c7 cells. | Q39770215 | ||
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation | Q39773986 | ||
Ikappa B kinasebeta/nuclear factor-kappaB activation controls the development of liver metastasis by way of interleukin-6 expression | Q39788628 | ||
Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli | Q40312088 | ||
Helicobacter pylori induces IkappaB kinase alpha nuclear translocation and chemokine production in gastric epithelial cells | Q43164932 | ||
Loss of ATM sensitizes against O6-methylguanine triggered apoptosis, SCEs and chromosomal aberrations | Q44792776 | ||
Replication stress activates DNA polymerase alpha-associated Chk1. | Q44803036 | ||
Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis. | Q45951895 | ||
Quantification of DNA strand breaks and abasic sites by oxime derivatization and accelerator mass spectrometry: application to gamma-radiation and peroxynitrite | Q46554572 | ||
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis | Q46576855 | ||
Determination of apurinic/apyrimidinic lesions in DNA with high-performance liquid chromatography and tandem mass spectrometry | Q46950755 | ||
The response of Parp knockout mice against DNA damaging agents. | Q52538829 | ||
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. | Q52901092 | ||
Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo | Q59098643 | ||
The protective role of thiol reducing agents in the in vitro inhibition of rat liver DNA methylase by direct acting carcinogens | Q71822513 | ||
P433 | issue | 14 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
genotoxicity | Q1009245 | ||
P304 | page(s) | 1854-1862 | |
P577 | publication date | 2012-05-21 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | Promotion of DNA repair by nuclear IKKβ phosphorylation of ATM in response to genotoxic stimuli | |
P478 | volume | 32 |
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Q35745041 | A quasi-quantitative dual multiplexed immunoblot method to simultaneously analyze ATM and H2AX Phosphorylation in human peripheral blood mononuclear cells |
Q38154199 | An unconventional role of BMP-Smad1 signaling in DNA damage response: a mechanism for tumor suppression |
Q47159733 | Context-Dependent Role of IKKβ in Cancer |
Q35799909 | Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma : ATM, ATR and FA in lung carcinoma |
Q27005588 | New approaches to radiation protection |
Q38224263 | Non-conventional functions for NF-κB members: the dark side of NF-κB. |
Q92096585 | Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p |
Q37536497 | Proteasome inhibition increases recruitment of IκB kinase β (IKKβ), S536P-p65, and transcription factor EGR1 to interleukin-8 (IL-8) promoter, resulting in increased IL-8 production in ovarian cancer cells |
Q36951585 | Regulation of anoikis by deleted in breast cancer-1 (DBC1) through NF-κB. |
Q37594798 | Sensitization of melanoma cells to alkylating agent-induced DNA damage and cell death via orchestrating oxidative stress and IKKβ inhibition |
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