Na(V)1.1 channels are critical for intercellular communication in the suprachiasmatic nucleus and for normal circadian rhythms

scientific article published on 5 January 2012

Na(V)1.1 channels are critical for intercellular communication in the suprachiasmatic nucleus and for normal circadian rhythms is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2012PNAS..109E.368H
P356DOI10.1073/PNAS.1115729109
P932PMC publication ID3277539
P698PubMed publication ID22223655
P5875ResearchGate publication ID235610713

P2093author name stringMichael D Schwartz
William A Catterall
Frank H Yu
James B Hurley
Jonathan D Linton
Horacio O de la Iglesia
Sung Han
Martha M Bosma
P2860cites workSynchronization-induced rhythmicity of circadian oscillators in the suprachiasmatic nucleusQ21145668
Modeling of a human circadian mutation yields insights into clock regulation by PER2Q24292897
RIGUI, a putative mammalian ortholog of the Drosophila period geneQ24316037
De novo mutations in the sodium-channel gene SCN1A cause severe myoclonic epilepsy of infancyQ24533495
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndromeQ27863695
Circadian oscillation of a mammalian homologue of the Drosophila period geneQ27867702
Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei.Q27867706
The VPAC(2) receptor is essential for circadian function in the mouse suprachiasmatic nucleiQ28207565
Mice lacking the PACAP type I receptor have impaired photic entrainment and negative masking.Q43995519
Sodium channel alpha1-subunit mutations in severe myoclonic epilepsy of infancy and infantile spasms.Q44592858
Synchronization of cellular clocks in the suprachiasmatic nucleusQ44664187
Impaired masking responses to light in melanopsin-knockout miceQ44696591
A GABAergic mechanism is necessary for coupling dissociable ventral and dorsal regional oscillators within the circadian clockQ46510197
Calcium response to retinohypothalamic tract synaptic transmission in suprachiasmatic nucleus neurons.Q46932807
In situ hybridization of suprachiasmatic nucleus slicesQ48212295
Seasonal encoding by the circadian pacemaker of the SCN.Q48263183
GABA is the principal neurotransmitter of the circadian systemQ48333442
Differential expression of membrane conductances underlies spontaneous event initiation by rostral midline neurons in the embryonic mouse hindbrain.Q48464689
A TTX-sensitive local circuit is involved in the expression of PK2 and BDNF circadian rhythms in the mouse suprachiasmatic nucleus.Q48518320
GABA in the mammalian suprachiasmatic nucleus and its role in diurnal rhythmicity.Q48685135
Severe myoclonic epilepsy of infants (Dravet syndrome): natural history and neuropsychological findings.Q50302268
GABA synchronizes clock cells within the suprachiasmatic circadian clock.Q52170283
The chi square periodogram: Its utility for analysis of circadian rhythmsQ52793412
Two coupled oscillators: Simulations of the circadian pacemaker in mammalian activity rhythmsQ67300339
Differential subcellular localization of the RI and RII Na+ channel subtypes in central neuronsQ69366003
GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regionsQ72172918
Forced desynchronization of dual circadian oscillators within the rat suprachiasmatic nucleusQ80032767
Involvement of calcium-calmodulin protein kinase but not mitogen-activated protein kinase in light-induced phase delays and Per gene expression in the suprachiasmatic nucleus of the hamsterQ95721128
Phototransduction by retinal ganglion cells that set the circadian clockQ28217956
Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behaviorQ28252722
Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancyQ28513583
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancyQ28585126
Molecular analysis of mammalian circadian rhythmsQ29618036
A clockwork web: circadian timing in brain and periphery, in health and diseaseQ29618069
Linking neural activity and molecular oscillations in the SCN.Q30416917
A diversity of paracrine signals sustains molecular circadian cycling in suprachiasmatic nucleus circuits.Q30430926
Dissociation of circadian and light inhibition of melatonin release through forced desynchronization in the rat.Q30436476
Differential response of Period 1 expression within the suprachiasmatic nucleus.Q30437073
Phase shifting capacity of the circadian pacemaker determined by the SCN neuronal network organizationQ33420395
Masking: history, definitions, and measurementQ33708252
The circadian visual system, 2005.Q33991981
Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythmsQ34058703
Suprachiasmatic nucleus: cell autonomy and network propertiesQ34098176
Photic and circadian regulation of c-fos gene expression in the hamster suprachiasmatic nucleus.Q34155533
Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript.Q34452201
A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light.Q34452206
Neurotransmitters of the retino-hypothalamic tractQ34732744
Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neuronsQ35117408
Fast delayed rectifier potassium current: critical for input and output of the circadian systemQ35132252
Age-related decline in circadian outputQ35163333
Entrainment of Circadian ProgramsQ35554766
Epileptic syndromes and visually induced seizuresQ35620703
Phase resetting light pulses induce Per1 and persistent spike activity in a subpopulation of biological clock neuronsQ35763364
Come together, right...now: synchronization of rhythms in a mammalian circadian clock.Q36318772
Excitatory actions of GABA in the suprachiasmatic nucleus.Q36944420
NaV1.1 channels and epilepsyQ37701079
Physiology of circadian entrainmentQ37776089
Insights into pathophysiology and therapy from a mouse model of Dravet syndromeQ37861266
Coping with Dravet syndrome: parental experiences with a catastrophic epilepsyQ39347494
Circadian timekeeping in BALB/c and C57BL/6 inbred mouse strains.Q41208726
Phase misalignment between suprachiasmatic neuronal oscillators impairs photic behavioral phase shifts but not photic induction of gene expressionQ41818748
GABAergic signaling induces divergent neuronal Ca2+ responses in the suprachiasmatic nucleus networkQ43107316
Food intake, water intake, and drinking spout side preference of 28 mouse strainsQ43237768
Excitation by GABA in the SCN reaches its time and place (Commentary on Irwin & Allen).Q43263245
Suprachiasmatic nucleus in the mouse: retinal innervation, intrinsic organization and efferent projectionsQ43764348
P4510describes a project that usesImageJQ1659584
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectcircadian rhythmQ208353
P304page(s)E368-77
P577publication date2012-01-05
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleNa(V)1.1 channels are critical for intercellular communication in the suprachiasmatic nucleus and for normal circadian rhythms
P478volume109

Reverse relations

cites work (P2860)
Q42732884"It was the interneuron with the parvalbumin in the hippocampus!" "no, it was the pyramidal cell with the glutamate in the cortex!" searching for clues to the mechanism of dravet syndrome - the plot thickens
Q47387278Accumulation of rest deficiency precedes sudden death of epileptic Kv1.1 knockout mice, a model of sudden unexpected death in epilepsy
Q30419321Aging differentially affects the re-entrainment response of central and peripheral circadian oscillators
Q39427173Alteration of circadian rhythm during epileptogenesis: implications for the suprachiasmatic nucleus circuits
Q42014678Altered sleep regulation in a mouse model of SCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+).
Q36252621Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission.
Q41379608Behavioral Comorbidities and Drug Treatments in a Zebrafish scn1lab Model of Dravet Syndrome
Q53426995Cell-Type-Specific Shank2 Deletion in Mice Leads to Differential Synaptic and Behavioral Phenotypes.
Q48136577Circadian control of pain and neuroinflammation.
Q26751434Collective timekeeping among cells of the master circadian clock
Q33702545Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome
Q37344330Dynamic interactions mediated by nonredundant signaling mechanisms couple circadian clock neurons
Q47288120Forty Years of Sodium Channels: Structure, Function, Pharmacology, and Epilepsy
Q27308208Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome
Q92185508Hippocampal deletion of NaV1.1 channels in mice causes thermal seizures and cognitive deficit characteristic of Dravet Syndrome
Q28593648I(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activity
Q37080755IA Channels Encoded by Kv1.4 and Kv4.2 Regulate Circadian Period of PER2 Expression in the Suprachiasmatic Nucleus
Q34002328Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome
Q90182655Impairment of Sharp-Wave Ripples in a Murine Model of Dravet Syndrome
Q38466267Improved Methods for Fluorescence Microscopy Detection of Macromolecules at the Axon Initial Segment
Q36691419In synch but not in step: Circadian clock circuits regulating plasticity in daily rhythms
Q90265798Ion Channels Controlling Circadian Rhythms in Suprachiasmatic Nucleus Excitability
Q59314000Mining Massive Amounts of Genomic Data: A Semiparametric Topic Modeling Approach
Q26800090Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels
Q90064889NaV1.1 and NaV1.6 selective compounds reduce the behavior phenotype and epileptiform activity in a novel zebrafish model for Dravet Syndrome
Q34491631Network-mediated encoding of circadian time: the suprachiasmatic nucleus (SCN) from genes to neurons to circuits, and back.
Q38960807Practical approaches to adverse outcome pathway development and weight-of-evidence evaluation as illustrated by ecotoxicological case studies
Q55471525Preclinical Animal Models for Dravet Syndrome: Seizure Phenotypes, Comorbidities and Drug Screening.
Q48118077RORA gene rs12912233 and rs880626 polymorphisms and their interaction with SCN1A rs3812718 in the risk of epilepsy: a case-control study in Malaysia
Q34067359Role of the dorsal medial habenula in the regulation of voluntary activity, motor function, hedonic state, and primary reinforcement
Q27312857Role of vasoactive intestinal peptide in the light input to the circadian system
Q38080206Sleep and epilepsy: exploring an intriguing relationship with a translational approach
Q35472627Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome
Q90677669Sleep, brain development, and autism spectrum disorders: Insights from animal models
Q54220701Src family tyrosine kinase inhibitors suppress Nav1.1 expression in cultured rat spiral ganglion neurons.
Q30538288Sudden unexpected death in a mouse model of Dravet syndrome
Q35876097Sustained activation of GABAA receptors in the suprachiasmatic nucleus mediates light-induced phase delays of the circadian clock: a novel function of ionotropic receptors
Q36776559Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome
Q47318440The Dorsal Medial Habenula Minimally Impacts Circadian Regulation of Locomotor Activity and Sleep.
Q97883298The Molecular Genetic Interaction Between Circadian Rhythms and Susceptibility to Seizures and Epilepsy
Q38123956The SCN1A gene variants and epileptic encephalopathies
Q55077934The Suprachiasmatic Nucleus and the Intergeniculate Leaflet of the Flat-Faced Fruit-Eating Bat (Artibeus planirostris): Retinal Projections and Neurochemical Anatomy.
Q38055661The clock shop: coupled circadian oscillators.
Q39022788The dynamics of GABA signaling: Revelations from the circadian pacemaker in the suprachiasmatic nucleus.
Q64102396Time of Day and a Ketogenic Diet Influence Susceptibility to SUDEP in Mice
Q36504400Topological specificity and hierarchical network of the circadian calcium rhythm in the suprachiasmatic nucleus
Q35044774Vasoactive intestinal polypeptide (VIP)-expressing neurons in the suprachiasmatic nucleus provide sparse GABAergic outputs to local neurons with circadian regulation occurring distal to the opening of postsynaptic GABAA ionotropic receptors
Q41894542What activates inactivation?

Search more.