Functional selective oxytocin-derived agonists discriminate between individual G protein family subtypes

scientific article published on 8 November 2011

Functional selective oxytocin-derived agonists discriminate between individual G protein family subtypes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.277178
P932PMC publication ID3281696
P698PubMed publication ID22069312

P50authorMarta BusnelliQ57420675
Céline GalèsQ73251493
Michel BouvierQ38326685
Bice ChiniQ39691750
P2093author name stringCeline Galés
Aude Saulière
Maurice Manning
P2860cites workTwo aromatic residues regulate the response of the human oxytocin receptor to the partial agonist arginine vasopressinQ41150726
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Design of peptide oxytocin antagonists with strikingly higher affinities and selectivities for the human oxytocin receptor than atosibanQ46478518
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Scientists probe oxytocin therapy for social deficits in autism, schizophreniaQ50312740
Internalization and desensitization of the oxytocin receptor is inhibited by Dynamin and clathrin mutants in human embryonic kidney 293 cells.Q53656341
Oxytocin and Vasopressin V1a and V2 Receptors Form Constitutive Homo- and Heterodimers during BiosynthesisQ56648628
Localization of the human oxytocin receptor in caveolin-1 enriched domains turns the receptor-mediated inhibition of cell growth into a proliferative responseQ57369934
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Nephrogenic diabetes insipidus: functional analysis of new AVPR2 mutations identified in Italian familiesQ73811998
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Differential association modes of the thrombin receptor PAR1 with Galphai1, Galpha12, and beta-arrestin 1Q84090140
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Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*Q28208920
Binding domains of the oxytocin receptor for the selective oxytocin receptor antagonist barusiban in comparison to the agonists oxytocin and carbetocinQ28237545
Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V1a, V1b, V2 and OT receptors: research tools and potential therapeutic agentsQ28288577
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Coupling of oxytocin receptor to G proteins in rat myometrium during labor: Gi receptor interactionQ28578269
Oxytocin receptors differentially signal via Gq and Gi proteins in pregnant and nonpregnant rat uterine myocytes: implications for myometrial contractilityQ30483332
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The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behaviorQ33761364
Teaching old receptors new tricks: biasing seven-transmembrane receptorsQ33985759
An improved bioluminescence resonance energy transfer strategy for imaging intracellular events in single cells and living subjectsQ34164718
A Gly/Ala switch contributes to high affinity binding of benzoxazinone-based non-peptide oxytocin receptor antagonists.Q34383214
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Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light outputQ34549716
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Seven-transmembrane receptor signaling through beta-arrestinQ36305171
Improved radiotracing of oxytocin receptor-expressing tumours using the new [111In]-DOTA-Lys8-deamino-vasotocin analogueQ36671779
Oxytocin Induces the Migration of Prostate Cancer Cells: Involvement of the Gi-Coupled Signaling PathwayQ39675130
Dual modulation of inward rectifier potassium currents in olfactory neuronal cells by promiscuous G protein coupling of the oxytocin receptorQ39691630
Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands.Q39827773
Intracellular trafficking of the human oxytocin receptor: evidence of receptor recycling via a Rab4/Rab5 "short cycle".Q39898138
Dopamine receptor-interacting protein 78 acts as a molecular chaperone for Ggamma subunits before assembly with GbetaQ40158543
Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3.Q40173381
The DRY motif as a molecular switch of the human oxytocin receptor.Q40393618
Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins.Q40420767
Evidence of oxytocin/oxytocin receptor interplay in human prostate gland and carcinomas.Q40514478
Oxytocin receptor elicits different EGFR/MAPK activation patterns depending on its localization in caveolin-1 enriched domainsQ40637745
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectoxytocinQ169960
protein familyQ417841
P304page(s)3617-3629
P577publication date2011-11-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleFunctional selective oxytocin-derived agonists discriminate between individual G protein family subtypes
P478volume287