| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M101450200 |
| P698 | PubMed publication ID | 11279203 |
| P50 | author | Marc Caron | Q64858849 |
| P2093 | author name string | S A Laporte | |
| L S Barak | |||
| J A Holt | |||
| R H Oakley | |||
| P2860 | cites work | beta-Arrestin: a protein that regulates beta-adrenergic receptor function | Q24305145 |
| P433 | issue | 22 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | G protein-coupled receptor | Q38173 |
| endocytosis | Q189814 | ||
| P304 | page(s) | 19452-60 | |
| P577 | publication date | 2001-06-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis* | |
| P478 | volume | 276 |
| Q35810546 | 5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or beta-arrestin signaling. |
| Q28581149 | A Ser/Thr cluster within the C-terminal domain of the rat prostaglandin receptor EP3alpha is essential for agonist-induced phosphorylation, desensitization and internalization |
| Q24647504 | ATP stimulates GRK-3 phosphorylation and beta-arrestin-2-dependent internalization of P2X7 receptor |
| Q28299947 | Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2 |
| Q42097100 | Adaptor protein-2 interaction with arrestin regulates GPCR recycling and apoptosis |
| Q37402789 | Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways. |
| Q37150973 | Agonist-biased trafficking of somatostatin receptor 2A in enteric neurons |
| Q39979395 | Agonist-dependent internalization and trafficking of the human prostacyclin receptor: a direct role for Rab5a GTPase |
| Q28215231 | Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin |
| Q33508707 | Amphioxus (Branchiostoma floridae) has orthologs of vertebrate odorant receptors |
| Q34580057 | An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization |
| Q41195003 | Angiotensin II receptors and peritoneal dialysis-induced peritoneal fibrosis |
| Q61772061 | Arrestin Variants Display Differential Binding Characteristics for the PhosphorylatedN-Formyl Peptide Receptor Carboxyl Terminus |
| Q37351549 | Arrestin3 mediates D(2) dopamine receptor internalization |
| Q34540902 | Arresting developments in heptahelical receptor signaling and regulation |
| Q34672108 | Arrestins differentially regulate histamine- and oxytocin-evoked phospholipase C and mitogen-activated protein kinase signalling in myometrial cells. |
| Q55108338 | Behavioral Characterization of β-Arrestin 1 Knockout Mice in Anxiety-Like and Alcohol Behaviors. |
| Q24320156 | Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling |
| Q34450017 | Beta-arrestin and Mdm2, unsuspected partners in signaling from the cell surface |
| Q33436593 | Beta-arrestin-based Bret2 screening assay for the "non"-beta-arrestin binding CB1 receptor |
| Q50511192 | Beta-arrestin2 as a competitor for GRK2 interaction with the GLP-1 receptor upon receptor activation. |
| Q34569418 | Beta-arrestin2-mediated internalization of mammalian odorant receptors. |
| Q33890802 | Beyond desensitization: physiological relevance of arrestin-dependent signaling. |
| Q64097803 | Biased Signaling and Allosteric Modulation at the FSHR |
| Q47648103 | Biased signaling by thyroid-stimulating hormone receptor-specific antibodies determines thyrocyte survival in autoimmunity. |
| Q28476374 | Biased signaling of the angiotensin II type 1 receptor can be mediated through distinct mechanisms |
| Q33690721 | Bimolecular fluorescence complementation: lighting up seven transmembrane domain receptor signalling networks |
| Q50970453 | C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways. |
| Q24300165 | C5L2 is a functional receptor for acylation-stimulating protein |
| Q39597237 | CK2 phosphorylation of an acidic Ser/Thr di-isoleucine motif in the Na+/H+ exchanger NHE5 isoform promotes association with beta-arrestin2 and endocytosis. |
| Q35009538 | Carboxyl-terminal and intracellular loop sites for CRF1 receptor phosphorylation and beta-arrestin-2 recruitment: a mechanism regulating stress and anxiety responses |
| Q50707853 | Cell imaging assays for G protein-coupled receptor internalization: application to high-throughput screening. |
| Q24299866 | Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer |
| Q36184275 | Chemokine receptor internalization and intracellular trafficking |
| Q34389558 | Classical and new roles of beta-arrestins in the regulation of G-protein-coupled receptors |
| Q39324870 | Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling |
| Q36191614 | Composition and function of g protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity. |
| Q24320381 | Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network |
| Q39236344 | Depletion of β-arrestin2 in hepatic stellate cells reduces cell proliferation via ERK pathway |
| Q37585127 | Desensitization of human CRF2(a) receptor signaling governed by agonist potency and βarrestin2 recruitment. |
| Q39711191 | Development and validation of algorithms for measuring G-protein coupled receptor activation in cells using the LSC-based imaging cytometer platform |
| Q47360713 | Development of a BRET2 screening assay using beta-arrestin 2 mutants |
| Q42522747 | Different mechanisms regulate lysophosphatidic acid (LPA)-dependent versus phorbol ester-dependent internalization of the LPA1 receptor |
| Q40582226 | Differential beta-arrestin trafficking and endosomal sorting of somatostatin receptor subtypes |
| Q40571692 | Differential desensitization, receptor phosphorylation, beta-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7. |
| Q42126128 | Differential regulation of endosomal GPCR/β-arrestin complexes and trafficking by MAPK |
| Q35533766 | Differential requirements for clathrin endocytic pathway components in cellular entry by Ebola and Marburg glycoprotein pseudovirions |
| Q42378659 | Differential signaling of the endogenous agonists at the beta2-adrenergic receptor |
| Q64077238 | Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation |
| Q24301356 | Down-modulation of the G-protein-coupled estrogen receptor, GPER, from the cell surface occurs via a trans-Golgi-proteasome pathway |
| Q41784510 | Down-regulation of cyclooxygenase-2 by the carboxyl tail of the angiotensin II type 1 receptor |
| Q36578821 | Endothelin-converting enzyme-1 degrades internalized somatostatin-14. |
| Q24301478 | Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestins |
| Q35921791 | Engagement of β-arrestin by transactivated insulin-like growth factor receptor is needed for V2 vasopressin receptor-stimulated ERK1/2 activation |
| Q42553690 | Engineered hyperphosphorylation of the β2-adrenoceptor prolongs arrestin-3 binding and induces arrestin internalization. |
| Q36746969 | Enhanced Uterine Contractility and Stillbirth in Mice Lacking G Protein-Coupled Receptor Kinase 6 (GRK6): Implications for Oxytocin Receptor Desensitization |
| Q34455388 | Evolutionary pattern in the OXT-OXTR system in primates: coevolution and positive selection footprints |
| Q30549924 | Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane mobility of neuropeptide Y receptors |
| Q36492513 | Function of non-visual arrestins in signaling and endocytosis of the gastrin-releasing peptide receptor (GRP receptor). |
| Q35763177 | Functional selective oxytocin-derived agonists discriminate between individual G protein family subtypes |
| Q34580340 | G Protein and β-arrestin signaling bias at the ghrelin receptor |
| Q35881875 | G Protein-Coupled Receptor Kinase 2 (GRK2) and 5 (GRK5) Exhibit Selective Phosphorylation of the Neurotensin Receptor in Vitro |
| Q39017722 | G protein coupled receptors signaling pathways implicate in inflammatory and immune response of rheumatoid arthritis |
| Q40462646 | G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation. |
| Q33848408 | G protein-coupled receptor sorting to endosomes and lysosomes |
| Q37209133 | G protein-independent cell-based assays for drug discovery on seven-transmembrane receptors |
| Q40281519 | G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer |
| Q28204866 | GIPC Binds to the Human Lutropin Receptor (hLHR) through an Unusual PDZ Domain Binding Motif, and It Regulates the Sorting of the Internalized Human Choriogonadotropin and the Density of Cell Surface hLHR |
| Q28277702 | GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling |
| Q36440674 | GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling |
| Q90148445 | Genetic code expansion and photocross-linking identify different β-arrestin binding modes to the angiotensin II type 1 receptor |
| Q36977659 | Glucagon receptor recycling: role of carboxyl terminus, beta-arrestins, and cytoskeleton |
| Q47394219 | Heterologous phosphorylation-induced formation of a stability lock permits regulation of inactive receptors by β-arrestins |
| Q28209959 | Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2 |
| Q35029422 | Hybrid formation between the intracellular faces of the bradykinin B2 and angiotensin II AT1 receptors and signal transduction. |
| Q36412846 | Identification and characterization of distinct C-terminal domains of the human hydroxycarboxylic acid receptor-2 that are essential for receptor export, constitutive activity, desensitization, and internalization |
| Q35921720 | Identification and profiling of novel α1A-adrenoceptor-CXC chemokine receptor 2 heteromer. |
| Q40626854 | Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions |
| Q40601716 | Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin receptor EP4 that is essential for agonist-induced beta-arrestin1 recruitment but differs from the apparent principal phosphorylation site |
| Q28565687 | Identification of a short linear sequence present in the C-terminal tail of the rat follitropin receptor that modulates arrestin-3 binding in a phosphorylation-independent fashion |
| Q34467542 | Identification of serine 348 on the apelin receptor as a novel regulatory phosphorylation site in apelin-13-induced G protein-independent biased signaling |
| Q37551248 | Illuminating the life of GPCRs |
| Q64112727 | In vitro comparison of liposomal drug delivery systems targeting the oxytocin receptor: a potential novel treatment for obstetric complications |
| Q99629092 | Individual phosphorylation sites at the C-terminus of the apelin receptor play different roles in signal transduction |
| Q45212981 | Inhibition of chemoattractant N-formyl peptide receptor trafficking by active arrestins |
| Q40765935 | Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association |
| Q40488751 | Internalization of the human CRF receptor 1 is independent of classical phosphorylation sites and of beta-arrestin 1 recruitment |
| Q47612221 | Intracellular Trafficking of Gonadotropin Receptors in Health and Disease |
| Q39898138 | Intracellular trafficking of the human oxytocin receptor: evidence of receptor recycling via a Rab4/Rab5 "short cycle". |
| Q40509065 | Involvement of a cytoplasmic-tail serine cluster in urotensin II receptor internalization. |
| Q57369934 | Localization of the human oxytocin receptor in caveolin-1 enriched domains turns the receptor-mediated inhibition of cell growth into a proliferative response |
| Q37099122 | ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse |
| Q39411727 | Mapping structural determinants within third intracellular loop that direct signaling specificity of type 1 corticotropin-releasing hormone receptor |
| Q34772867 | Maturation of respiratory control in the behaving mammal |
| Q39473235 | Mechanisms of melanocortin-2 receptor (MC2R) internalization and recycling in human embryonic kidney (hek) cells: identification of Key Ser/Thr (S/T) amino acids |
| Q35158385 | Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors |
| Q36553327 | Modulation of methuselah expression targeted to Drosophila insulin-producing cells extends life and enhances oxidative stress resistance. |
| Q47739826 | Molecular Basis of Oxytocin Receptor Signalling in the Brain: What We Know and What We Need to Know |
| Q41895362 | Molecular determinants of orexin receptor-arrestin-ubiquitin complex formation |
| Q44904450 | Molecular identification and characterization of three isoforms of tachykinin NK(1)-like receptors in the cane toad Bufo marinus |
| Q36773326 | Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors |
| Q40110003 | Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET. |
| Q35213474 | Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling |
| Q44211079 | N-formyl peptide receptor phosphorylation domains differentially regulate arrestin and agonist affinity |
| Q24658250 | Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons |
| Q44237516 | Neurokinin-1 versus mu-opioid receptor binding in rat nucleus tractus solitarius after single and recurrent intermittent hypoxia |
| Q37270438 | Neuropeptide diversity and the regulation of social behavior in New World primates |
| Q35922475 | Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. |
| Q37000847 | Non-synonymous single-nucleotide variations of the human oxytocin receptor gene and autism spectrum disorders: a case-control study in a Japanese population and functional analysis. |
| Q34581041 | Osteoblast regulation via ligand-activated nuclear trafficking of the oxytocin receptor |
| Q26781668 | Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits |
| Q34476734 | Oxytocin exposure during labor among women with postpartum hemorrhage secondary to uterine atony |
| Q36377388 | Oxytocin--its role in male reproduction and new potential therapeutic uses |
| Q40182336 | Palmitoylation of the TPbeta isoform of the human thromboxane A2 receptor. Modulation of G protein: effector coupling and modes of receptor internalization |
| Q33670408 | Pasireotide and octreotide stimulate distinct patterns of sst2A somatostatin receptor phosphorylation |
| Q34007358 | Pharmacological characterization of a small-molecule agonist for the chemokine receptor CXCR3 |
| Q40120465 | Phosphorylation of the delta-opioid receptor regulates its beta-arrestins selectivity and subsequent receptor internalization and adenylyl cyclase desensitization |
| Q39972706 | Phosphorylation state of mu-opioid receptor determines the alternative recycling of receptor via Rab4 or Rab11 pathway |
| Q40097564 | Possible involvement of post-dopamine D2 receptor signalling components in the pathophysiology of schizophrenia. |
| Q42595255 | Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes. |
| Q50600080 | Prolonged RXFP1 and RXFP2 signaling can be explained by poor internalization and a lack of beta-arrestin recruitment. |
| Q35322050 | Protein phosphatase 2A mediates resensitization of the neurokinin 1 receptor. |
| Q38675387 | Rapid dephosphorylation of G protein-coupled receptors by protein phosphatase 1β is required for termination of β-arrestin-dependent signaling. |
| Q34286857 | Receptor trafficking via the perinuclear recycling compartment accompanied by cell division is necessary for permanent neurotensin cell sensitization and leads to chronic mitogen-activated protein kinase activation |
| Q36008285 | Receptor-mediated tumor targeting with radiopeptides. Part 1. General concepts and methods: applications to somatostatin receptor-expressing tumors |
| Q37515337 | Receptor-mediated tumor targeting with radiopeptides. Part 1. General principles and methods |
| Q40558816 | Recycling and resensitization of the neurokinin 1 receptor. Influence of agonist concentration and Rab GTPases. |
| Q35579635 | Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases |
| Q29619598 | Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals |
| Q40636866 | Regulation of V2 vasopressin receptor degradation by agonist-promoted ubiquitination |
| Q48102498 | Regulation of corticotropin releasing hormone receptor (CRH-R) in the rat anterior pituitary as assessed by radioimmunoassay |
| Q41905591 | Regulation of membrane cholecystokinin-2 receptor by agonists enables classification of partial agonists as biased agonists. |
| Q33642196 | Regulation of oxytocin receptor responsiveness by G protein-coupled receptor kinase 6 in human myometrial smooth muscle |
| Q28266829 | Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors |
| Q35197367 | Role of Beta-arrestin 2 downstream of dopamine receptors in the Basal Ganglia. |
| Q43689427 | Role of G protein-coupled receptors-microRNA interactions in gastrointestinal pathophysiology. |
| Q37166245 | Role of PTH1R internalization in osteoblasts and bone mass using a phosphorylation-deficient knock-in mouse model. |
| Q36763812 | Role of Ubiquitination in Endocytic Trafficking of G‐Protein‐Coupled Receptors |
| Q36197653 | Role of rhodopsin and arrestin phosphorylation in retinal degeneration of Drosophila |
| Q44628581 | Selective Interaction of ARF1 with the Carboxy-Terminal Tail Domain of the 5-HT2A Receptor |
| Q34678084 | Ser352 and Ser354 in the carboxyl terminus of the human P2Y1 receptor are required for agonist‐promoted phosphorylation and internalization in MDCK cells |
| Q39152899 | Sphingosine 1-Phosphate Receptor 1 Signaling in Mammalian Cells |
| Q40517882 | Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2. |
| Q34947494 | Temporal profiling of orexin receptor-arrestin-ubiquitin complexes reveals differences between receptor subtypes |
| Q39381430 | The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling |
| Q33599835 | The G Protein-Coupled Receptor UT of the Neuropeptide Urotensin II Displays Structural and Functional Chemokine Features |
| Q40083721 | The Oxytocin Product Correlates with Total Oxytocin Received during Labor: A Research Methods Study |
| Q35105386 | The Use of Biosensors to Study GPCR Function: Applications for High-Content Screening |
| Q37236186 | The arrestin fold: variations on a theme |
| Q28185824 | The association of arrestin-3 with the follitropin receptor depends on receptor activation and phosphorylation |
| Q46447110 | The association of single-nucleotide polymorphisms in the oxytocin receptor and G protein-coupled receptor kinase 6 (GRK6) genes with oxytocin dosing requirements and labor outcomes |
| Q37095372 | The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts. |
| Q34409674 | The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation. |
| Q37280156 | The influence of maternal body mass index on myometrial oxytocin receptor expression in pregnancy |
| Q35183866 | The ins and outs of G protein-coupled receptor trafficking |
| Q40207563 | The ligand-independent translocation assay: an enabling technology for screening orphan G protein-coupled receptors by arrestin recruitment |
| Q40678127 | The nature of the arrestin x receptor complex determines the ultimate fate of the internalized receptor |
| Q45261068 | The oxytocin receptor antagonist atosiban inhibits cell growth via a "biased agonist" mechanism |
| Q50335944 | The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation |
| Q35080956 | The stem cell-expressed receptor Lgr5 possesses canonical and functionally active molecular determinants critical to β-arrestin-2 recruitment |
| Q24657537 | The structural basis of arrestin-mediated regulation of G-protein-coupled receptors |
| Q40463546 | The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation. |
| Q36773331 | Therapeutic potential of β-arrestin- and G protein-biased agonists. |
| Q40672031 | Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination |
| Q35922381 | Trans-Golgi Network (TGN) as a regulatory node for β1-adrenergic receptor (β1AR) down-modulation and recycling |
| Q37096786 | Triphenylmethane dye activation of beta-arrestin |
| Q36363295 | Two serines in the distal C-terminus of the human ß1-adrenoceptor determine ß-arrestin2 recruitment |
| Q40254275 | Ubiquitin-dependent down-regulation of the neurokinin-1 receptor |
| Q24310278 | Ubiquitination of CXCR7 controls receptor trafficking |
| Q40416635 | Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. Distinct molecular events with different GRK2 requirements. |
| Q28214555 | beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin |
| Q24556620 | beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform |
| Q37527105 | beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1. |
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