Analysis of mutations and suppressors affecting interactions between the subunits of the HIV type 1 reverse transcriptase

scientific article published on June 2000

Analysis of mutations and suppressors affecting interactions between the subunits of the HIV type 1 reverse transcriptase is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2000PNAS...97.6334T
P356DOI10.1073/PNAS.97.12.6334
P932PMC publication ID18603
P698PubMed publication ID10841542
P5875ResearchGate publication ID12475855

P50authorGilda TachedjianQ57006431
P2093author name stringS P Goff
H E Aronson
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Site-specific mutagenesis of AIDS virus reverse transcriptaseQ28338101
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A new potent HIV-1 reverse transcriptase inhibitor. A synthetic peptide derived from the interface subunit domainsQ28371255
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitorQ29547710
Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and BQ29618922
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNAQ29620616
DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9Q29620728
Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV.Q34382153
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimerQ35623899
Genetic analysis of homomeric interactions of human immunodeficiency virus type 1 integrase using the yeast two-hybrid systemQ36662251
Identification of posttranscriptionally active inhibitory sequences in human immunodeficiency virus type 1 RNA: novel level of gene regulationQ36820531
Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptaseQ38296391
The p51 subunit of human immunodeficiency virus type 1 reverse transcriptase is essential in loading the p66 subunit on the template primerQ38337436
Alterations to the primer grip of p66 HIV-1 reverse transcriptase and their consequences for template-primer utilizationQ38355667
Detection of protein-protein interactions using different vectors in the two-hybrid systemQ40411234
Inhibition of human immunodeficiency virus type 1 reverse transcriptase dimerization using synthetic peptides derived from the connection domainQ41468615
Chemical crosslinking of the subunits of HIV-1 reverse transcriptase.Q42740741
Assays for retroviral reverse transcriptaseQ42831046
Protein-protein interactions of HIV-1 reverse transcriptase: implication of central and C-terminal regions in subunit bindingQ43867754
Dimerization of human immunodeficiency virus type 1 reverse transcriptase. A target for chemotherapeutic intervention.Q45860281
A leucine zipper-like motif may mediate HIV reverse transcriptase subunit bindingQ53759737
Epitope mapping of HIV-1 reverse transcriptase with monoclonal antibodies that inhibit polymerase and RNase H activitiesQ54686257
Generating yeast transcriptional activators containing no yeast protein sequences.Q54699189
Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors.Q55063317
Kinetic Analysis of Four HIV-1 Reverse Transcriptase Enzymes Mutated in the Primer Grip Region of p66Q59663006
Characterization of the dimerization process of HIV-1 reverse transcriptase heterodimer using intrinsic protein fluorescenceQ59663050
Modulation of HIV-1 reverse transcriptase function in "selectively deleted" p66/p51 heterodimersQ71606791
Structure/function studies of HIV-1 reverse transcriptase: Dimerization-defective mutant L289KQ72105897
Mixed reconstitution of mutated subunits of HIV-1 reverse transcriptase coexpressed in Escherichia coli - two tags tie it upQ74672747
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)6334-6339
P577publication date2000-06-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleAnalysis of mutations and suppressors affecting interactions between the subunits of the HIV type 1 reverse transcriptase
P478volume97

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cites work (P2860)
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