iRhom1 regulates proteasome activity via PAC1/2 under ER stress

scientific article published on 25 June 2015

iRhom1 regulates proteasome activity via PAC1/2 under ER stress is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SREP11559
P932PMC publication ID4479803
P698PubMed publication ID26109405
P5875ResearchGate publication ID279307628

P50authorYong-Keun JungQ37381138
P2093author name stringJieun Lee
Jisu Park
Huikyong Lee
WonJae Lee
YoungDoo Kim
Hye-Hyun Ahn
SangMi Shim
Se-hoon Hong
P2860cites workA heterodimeric complex that promotes the assembly of mammalian 20S proteasomesQ24292874
Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteinsQ24293182
Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signalingQ24298141
The proteasome maturation protein POMP facilitates major steps of 20S proteasome formation at the endoplasmic reticulumQ24298209
SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibitionQ24314585
DSCR2, a Down syndrome critical region protein, is localized to the endoplasmic reticulum of mammalian cellsQ24320353
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERADQ24324707
IFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient responseQ24531439
ADD66, a gene involved in the endoplasmic reticulum-associated degradation of alpha-1-antitrypsin-Z in yeast, facilitates proteasome activity and assembly.Q27932696
20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals.Q27936515
In and Out of the ER: Protein Folding, Quality Control, Degradation, and Related Human DiseasesQ28109625
Regulation of CD8+ T cell development by thymus-specific proteasomesQ28116400
Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysisQ28143710
Hsm3/S5b joins the ranks of 26S proteasome assembly chaperonesQ28236742
Cleaning up in the endoplasmic reticulum: ubiquitin in chargeQ28237362
Role of S5b/PSMD5 in proteasome inhibition caused by TNF-α/NFκB in higher eukaryotes.Q52742352
Decreased Proteasomal Activity Causes Age-Related Phenotypes and Promotes the Development of Metabolic AbnormalitiesQ64166847
Amyloid β-induced FOXRED2 mediates neuronal cell death via inhibition of proteasome activityQ82037546
TCF11 at the crossroads of oxidative stress and the ubiquitin proteasome systemQ83632349
ERAD: the long road to destructionQ28264823
Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback LoopQ28295179
The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnoverQ28299566
Activation of proteasome by insulin-like growth factor-I may enhance clearance of oxidized proteins in the brainQ33651979
Modularity of the Hrd1 ERAD complex underlies its diverse client rangeQ33717057
Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragmentsQ33878287
IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy fluxQ34033567
Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACEQ34247194
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPSQ34247201
Osmotic stress inhibits proteasome by p38 MAPK-dependent phosphorylationQ34438701
OCIAD2 activates γ-secretase to enhance amyloid β production by interacting with nicastrinQ35052013
Intracellular localization of proteasomesQ35097620
The proteasome: structure, function, and role in the cellQ35124091
Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulumQ35381401
Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growthQ36186343
Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targetingQ36226090
Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.Q36854847
Biting the hand that feeds: Rpn4-dependent feedback regulation of proteasome functionQ36866843
Rhomboids: 7 years of a new protease familyQ37330784
Lectin-like ERAD players in ER and cytosolQ37576338
Converging pathways in the occurrence of endoplasmic reticulum (ER) stress in Huntington's diseaseQ37824336
The Cdc48 machine in endoplasmic reticulum associated protein degradationQ37938259
DNA damage emergency: cellular garbage disposal to the rescue?Q38090434
Human rhomboid family-1 suppresses oxygen-independent degradation of hypoxia-inducible factor-1α in breast cancerQ39013705
A different pathway in the endoplasmic reticulum stress-induced expression of human HRD1 and SEL1 genesQ40060780
The interferon-gamma-inducible 11 S regulator (PA28) and the LMP2/LMP7 subunits govern the peptide production by the 20 S proteasome in vitroQ41283840
Characterization of the proteasome using native gel electrophoresisQ46794661
Ump1 extends yeast lifespan and enhances viability during oxidative stress: central role for the proteasome?Q46842805
Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition.Q48298684
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P304page(s)11559
P577publication date2015-06-25
P1433published inScientific ReportsQ2261792
P1476titleiRhom1 regulates proteasome activity via PAC1/2 under ER stress
P478volume5

Reverse relations

cites work (P2860)
Q57064857Human rhomboid family-1 modulates clathrin coated vesicle-dependent pro-transforming growth factor α membrane trafficking to promote breast cancer progression
Q39093579PERM Hypothesis: The Fundamental Machinery Able to Elucidate the Role of Xenobiotics and Hormesis in Cell Survival and Homeostasis
Q90673658Regulation of proteasome assembly and activity in health and disease
Q28070034Rhomboids, signalling and cell biology
Q64072139The molecular, cellular and pathophysiological roles of iRhom pseudoproteases
Q95650650The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
Q64097518The proteasome biogenesis regulator Rpn4 cooperates with the unfolded protein response to promote ER stress resistance
Q38559265Tuning the proteasome to brighten the end of the journey

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