Expression of Met/hepatocyte growth factor receptor gene and malignant behavior of musculoskeletal tumors.

scientific article published on October 1996

Expression of Met/hepatocyte growth factor receptor gene and malignant behavior of musculoskeletal tumors. is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID1865197
P698PubMed publication ID8863670

P50authorMassimo SerraQ38549348
P2093author name stringComoglio PM
Baldini N
Oliviero M
Manara MC
Scotlandi K
Di Renzo MF
Ferracini R
Martano M
P2860cites workIdentification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene ProductQ24310794
Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factorQ24555664
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applicationsQ24561689
Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptorQ24564783
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Molecular cloning and sequence analysis of the cDNA for a human serine protease reponsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XIIQ28115845
Structure, biosynthesis and biochemical properties of the HGF receptor in normal and malignant cellsQ28262825
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in miceQ29547898
Mechanisms of p53 loss in human sarcomasQ33722859
Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulationQ35277738
Hepatocyte growth factor and its receptor (c-MET) in prostatic carcinomaQ35796063
Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogeneQ36065558
Scatter factor induces blood vessel formation in vivoQ36141804
Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cellsQ36223889
Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis networkQ36557528
Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factorQ36705281
Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinasesQ37479257
Osteosarcoma: fifteen years laterQ39835579
Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene productQ40794270
Inducibility of neoplastic transformation by Fujinami sarcoma virus in an in vitro chick embryo model for osteosarcoma: (i) effect of differentiation and (ii) investigation for in vivo growth potential in athymic miceQ41132152
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growthQ41596252
Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factorQ41656206
Expression of the Met/HGF receptor in normal and neoplastic human tissuesQ41658755
c-met is amplified but not mutated in a cell line with an activated met tyrosine kinaseQ41690281
p53 expression and its relationship to DNA alterations in bone and soft tissue sarcomasQ42281236
The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumorsQ42473244
Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse developmentQ42770153
Met expression and sarcoma tumorigenicityQ42804653
Scatter factor is a fibroblast-derived modulator of epithelial cell mobilityQ42807925
Tyrosine kinase receptor indistinguishable from the c-met proteinQ42814654
Met proto-oncogene product is overexpressed in tumors of p53-deficient mice and tumors of Li-Fraumeni patients.Q42828029
Giant-cell tumor of boneQ43856120
Molecular cloning of a new transforming gene from a chemically transformed human cell line.Q45345810
Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 tranQ45350288
Overexpression of the c-MET/HGF receptor gene in human thyroid carcinomasQ48146638
Amplification of both c-myc and c-raf-1 oncogenes in a human osteosarcoma.Q55237135
c-fos expression induces bone tumors in transgenic miceQ58326983
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor geneQ59092154
Sequestration of a hepatocyte growth factor in extracellular matrix in normal adult rat liverQ67897413
Lung may have an endocrine function producing hepatocyte growth factor in response to injury of distal organsQ68052543
Biosynthesis of the protein encoded by the c-met proto-oncogeneQ69359093
Studies of the retinoblastoma gene in human sarcomasQ69670170
Expression of c-sis and other cellular proto-oncogenes in human sarcoma cell lines and biopsiesQ69751078
The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuitQ72560868
Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancerQ72571222
Sporadic amplification of the MYC gene in human osteosarcomasQ72721753
Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancerQ77555522
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1209-1219
P577publication date1996-10-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleExpression of Met/hepatocyte growth factor receptor gene and malignant behavior of musculoskeletal tumors
P478volume149

Reverse relations

cites work (P2860)
Q47303095Activated HGF-c-Met Axis in Head and Neck Cancer
Q35082747Acute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway
Q52665713Cabozantinib Affects Osteosarcoma Growth Through A Direct Effect On Tumor Cells and Modifications In Bone Microenvironment.
Q34700590Defective osteogenic differentiation in the development of osteosarcoma
Q42555042Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon
Q33275985Establishment of clival chordoma cell line MUG-CC1 and lymphoblastoid cells as a model for potential new treatment strategies
Q28817274Exploring targeted therapy of osteosarcoma using proteomics data
Q74453712Expression of Hepatocyte Growth Factor (HGF) and its Receptor (MET) in Medullary Carcinoma of the Thyroid
Q37306012Expression of Ovol2 is related to epithelial characteristics and shows a favorable clinical outcome in hepatocellular carcinoma
Q41908214Human Chondrosarcoma Cells Acquire an Epithelial-Like Gene Expression Pattern via an Epigenetic Switch: Evidence for Mesenchymal-Epithelial Transition during Sarcomagenesis.
Q79269259Impact of c-Met expression on angiogenesis in soft tissue sarcomas: correlation to microvessel-density
Q37201330MET and autism susceptibility: family and case-control studies
Q43201388Non-autocrine, constitutive activation of Met in human anaplastic thyroid carcinoma cells in culture
Q37263375Novel targets with potential therapeutic applications in osteosarcoma
Q36803600Osteosarcoma development and stem cell differentiation
Q42279434Overexpression of the hepatocyte growth factor (HGF) receptor (Met) and presence of a truncated and activated intracellular HGF receptor fragment in locally aggressive/malignant human musculoskeletal tumors.
Q28538117Separate and combined effects of DNMT and HDAC inhibitors in treating human multi-drug resistant osteosarcoma HosDXR150 cell line
Q36514299The Current and Future Therapies for Human Osteosarcoma
Q36194212Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion.
Q47588979c-Met tyrosine kinase receptor expression and function in human and canine osteosarcoma cells

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