| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2012PNAS..109.2648C |
| P356 | DOI | 10.1073/PNAS.1115575109 |
| P932 | PMC publication ID | 3289344 |
| P698 | PubMed publication ID | 22308389 |
| P5875 | ResearchGate publication ID | 221808891 |
| P50 | author | Manoel Arcisio-Miranda | Q79781367 |
| P2093 | author name string | Baron Chanda | |
| Robert J French | |||
| Brian W Jarecki | |||
| Deborah L Capes | |||
| P2860 | cites work | Cooccupancy of the outer vestibule of voltage-gated sodium channels by micro-conotoxin KIIIA and saxitoxin or tetrodotoxin | Q24609009 |
| Structural basis for the coupling between activation and inactivation gates in K(+) channels | Q24630519 | ||
| Structural mechanism of C-type inactivation in K(+) channels | Q24630547 | ||
| Charge movement associated with the opening and closing of the activation gates of the Na channels | Q24649965 | ||
| The crystal structure of a voltage-gated sodium channel | Q27670752 | ||
| A single residue differentiates between human cardiac and skeletal muscle Na+ channel slow inactivation | Q28363700 | ||
| Voltage-dependent gating at the KcsA selectivity filter | Q30439753 | ||
| Molecular determinants of gating at the potassium-channel selectivity filter | Q30439755 | ||
| Ultra-slow inactivation in mu1 Na+ channels is produced by a structural rearrangement of the outer vestibule | Q30447518 | ||
| Novel voltage clamp to record small, fast currents from ion channels expressed in Xenopus oocytes | Q30982526 | ||
| Molecular dynamics of the sodium channel pore vary with gating: interactions between P-segment motions and inactivation. | Q33852460 | ||
| The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4. | Q33869265 | ||
| Synergistic and antagonistic interactions between tetrodotoxin and mu-conotoxin in blocking voltage-gated sodium channels | Q33885974 | ||
| A new twist in the saga of charge movement in voltage-dependent ion channels | Q33896199 | ||
| Molecular motions within the pore of voltage-dependent sodium channels | Q33907113 | ||
| Mechanisms of sodium/calcium selectivity in sodium channels probed by cysteine mutagenesis and sulfhydryl modification | Q33915656 | ||
| Ion permeation and block of the gating pore in the voltage sensor of NaV1.4 channels with hypokalemic periodic paralysis mutations | Q34028248 | ||
| On the structural basis for ionic selectivity among Na+, K+, and Ca2+ in the voltage-gated sodium channel | Q34041257 | ||
| Rapid and slow voltage-dependent conformational changes in segment IVS6 of voltage-gated Na(+) channels | Q34173224 | ||
| Saxitoxin and tetrodotoxin. Electrostatic effects on sodium channel gating current in crayfish axons | Q34257494 | ||
| Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction | Q34684384 | ||
| Discrimination of muscle and neuronal Na-channel subtypes by binding competition between [3H]saxitoxin and mu-conotoxins | Q35617896 | ||
| Gating currents associated with intramembrane charge displacement in HERG potassium channels | Q35918682 | ||
| Cross talk between activation and slow inactivation gates of Shaker potassium channels | Q36295859 | ||
| A Na+ channel mutation linked to hypokalemic periodic paralysis exposes a proton-selective gating pore | Q36299707 | ||
| Probing the cavity of the slow inactivated conformation of shaker potassium channels | Q36299751 | ||
| How does the W434F mutation block current in Shaker potassium channels? | Q36411800 | ||
| Time course of TEA(+)-induced anomalous rectification in squid giant axons | Q36427295 | ||
| Batrachotoxin-activated Na+ channels in planar lipid bilayers. Competition of tetrodotoxin block by Na+ | Q36433606 | ||
| Effect of alkali metal cations on slow inactivation of cardiac Na+ channels | Q36435851 | ||
| Correlation between charge movement and ionic current during slow inactivation in Shaker K+ channels | Q36435954 | ||
| Macroscopic Na+ currents in the "Nonconducting" Shaker potassium channel mutant W434F. | Q36436044 | ||
| Protein rearrangements underlying slow inactivation of the Shaker K+ channel | Q36436101 | ||
| Structural implications of fluorescence quenching in the Shaker K+ channel | Q36436115 | ||
| A structural rearrangement in the sodium channel pore linked to slow inactivation and use dependence | Q36436280 | ||
| Slow inactivation does not block the aqueous accessibility to the outer pore of voltage-gated Na channels | Q36436472 | ||
| Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation. | Q36436547 | ||
| Role of domain 4 in sodium channel slow inactivation | Q36442905 | ||
| Immobilizing the moving parts of voltage-gated ion channels | Q36444725 | ||
| Permeation of large tetra-alkylammonium cations through mutant and wild-type voltage-gated sodium channels as revealed by relief of block at high voltage | Q36444949 | ||
| Hysteresis in the voltage dependence of HCN channels: conversion between two modes affects pacemaker properties | Q36445714 | ||
| Block of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway | Q36445753 | ||
| Molecular motions of the outer ring of charge of the sodium channel: do they couple to slow inactivation? | Q36447224 | ||
| S4-based voltage sensors have three major conformations | Q36976792 | ||
| Deconstructing voltage sensor function and pharmacology in sodium channels | Q36983062 | ||
| The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na(+) channel | Q37280509 | ||
| Inactivation and recovery of sodium currents in cerebellar Purkinje neurons: evidence for two mechanisms | Q40178283 | ||
| Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue | Q40404449 | ||
| Dynamic rearrangement of the outer mouth of a K+ channel during gating | Q41212365 | ||
| P-loop flexibility in Na+ channel pores revealed by single- and double-cysteine replacements | Q41834191 | ||
| Tetrodotoxin block of sodium channels in rabbit Purkinje fibers. Interactions between toxin binding and channel gating | Q41934196 | ||
| The open pore conformation of potassium channels | Q42677283 | ||
| Mode shift of the voltage sensors in Shaker K+ channels is caused by energetic coupling to the pore domain | Q42722538 | ||
| The selectivity filter of the voltage-gated sodium channel is involved in channel activation | Q43624026 | ||
| Voltage clamp analysis of tetrodotoxin-sensitive and -insensitive sodium channels in rat muscle cells developing in vitro | Q43686357 | ||
| A proton pore in a potassium channel voltage sensor reveals a focused electric field | Q44757373 | ||
| Open-channel block by the cytoplasmic tail of sodium channel beta4 as a mechanism for resurgent sodium current | Q45233496 | ||
| Voltage-sensing arginines in a potassium channel permeate and occlude cation-selective pores | Q45252796 | ||
| A voltage-dependent gating transition induces use-dependent block by tetrodotoxin of rat IIA sodium channels expressed in Xenopus oocytes. | Q46007688 | ||
| Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels | Q46048873 | ||
| Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels | Q46066064 | ||
| Ion permeation through a voltage- sensitive gating pore in brain sodium channels having voltage sensor mutations | Q46615032 | ||
| A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties | Q48479782 | ||
| Calcium channel characteristics conferred on the sodium channel by single mutations | Q48494145 | ||
| External pore residue mediates slow inactivation in mu 1 rat skeletal muscle sodium channels. | Q48962979 | ||
| Global flexibility in a sensory receptor: a site-directed cross-linking approach | Q50200558 | ||
| A conserved ring of charge in mammalian Na+ channels: a molecular regulator of the outer pore conformation during slow inactivation. | Q50646634 | ||
| Molecular localization of an ion-binding site within the pore of mammalian sodium channels | Q51687082 | ||
| Interactions between a pore-blocking peptide and the voltage sensor of the sodium channel: an electrostatic approach to channel geometry. | Q52311328 | ||
| The aromatic binding site for tetraethylammonium ion on potassium channels | Q52443507 | ||
| Depth asymmetries of the pore-lining segments of the Na+ channel revealed by cysteine mutagenesis | Q71078149 | ||
| Evidence for voltage-dependent S4 movement in sodium channels | Q71909065 | ||
| Gated access to the pore of a voltage-dependent K+ channel | Q73564876 | ||
| A common anticonvulsant binding site for phenytoin, carbamazepine, and lamotrigine in neuronal Na+ channels | Q77388391 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | voltage | Q25428 |
| P304 | page(s) | 2648-2653 | |
| P577 | publication date | 2012-01-30 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor | |
| P478 | volume | 109 |
| Q37121989 | A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb |
| Q36516769 | A recessive Nav1.4 mutation underlies congenital myasthenic syndrome with periodic paralysis. |
| Q38204930 | Animal toxins influence voltage-gated sodium channel function. |
| Q37729614 | Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains |
| Q90019912 | Dehydrocrenatidine Inhibits Voltage-Gated Sodium Channels and Ameliorates Mechanic Allodia in a Rat Model of Neuropathic Pain |
| Q42597394 | Direct Measurement of Cardiac Na+ Channel Conformations Reveals Molecular Pathologies of Inherited Mutations. |
| Q33964031 | Disrupted coupling of gating charge displacement to Na+ current activation for DIIS4 mutations in hypokalemic periodic paralysis |
| Q37055488 | Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels. |
| Q41781394 | Enhancement of Closed-State Inactivation by Neutralization of S4 Arginines in Domain IV of a Sodium Channel |
| Q37646643 | Evolutionarily conserved intracellular gate of voltage-dependent sodium channels. |
| Q36977102 | Extracellular protons inhibit charge immobilization in the cardiac voltage-gated sodium channel |
| Q36436974 | Gating pore currents and the resting state of Nav1.4 voltage sensor domains |
| Q34024636 | Gating-pore currents demonstrate selective and specific modulation of individual sodium channel voltage-sensors by biological toxins |
| Q36363379 | Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels |
| Q87841107 | Improving the characterization of calcium channel gating pore currents with Stac3 |
| Q90470138 | Lidocaine binding enhances inhibition of Nav1.7 channels by the sulfonamide PF-05089771 |
| Q37695974 | Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. |
| Q38266367 | Molecular biology and biophysical properties of ion channel gating pores. |
| Q41666462 | Open-state stabilization in Kv channels: voltage-sensor relaxation and pore propping by a bound ion. |
| Q38728979 | Pharmacology of the Nav1.1 domain IV voltage sensor reveals coupling between inactivation gating processes |
| Q30392343 | Proton currents constrain structural models of voltage sensor activation |
| Q36620769 | Proton sensors in the pore domain of the cardiac voltage-gated sodium channel |
| Q36804623 | S1-S3 counter charges in the voltage sensor module of a mammalian sodium channel regulate fast inactivation |
| Q42211742 | Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Na(V)1.7 mutant channel. |
| Q35666325 | The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening. |
| Q26771787 | The hitchhiker's guide to the voltage-gated sodium channel galaxy |
| Q64954804 | The voltage-gated sodium channel pore exhibits conformational flexibility during slow inactivation. |
| Q33964075 | Tracking S4 movement by gating pore currents in the bacterial sodium channel NaChBac |
| Q30392501 | Understanding Sodium Channel Function and Modulation Using Atomistic Simulations of Bacterial Channel Structures. |
| Q36277894 | Use-dependent block of the voltage-gated Na(+) channel by tetrodotoxin and saxitoxin: effect of pore mutations that change ionic selectivity |
| Q36636613 | Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels I: wild-type skeletal muscle Na(V)1.4. |
| Q36636617 | Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels II: a periodic paralysis mutation in Na(V)1.4 (L689I) |
| Q41894542 | What activates inactivation? |
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