Effects of metformin on survival outcomes of lung cancer patients with type 2 diabetes mellitus: a meta-analysis

scientific article published on 12 October 2015

Effects of metformin on survival outcomes of lung cancer patients with type 2 diabetes mellitus: a meta-analysis is …
instance of (P31):
scholarly articleQ13442814
meta-analysisQ815382

External links are
P356DOI10.1007/S12094-015-1412-X
P698PubMed publication ID26459254

P2093author name stringX Liu
Z Wu
H-L Ji
Y-G Zhang
J-W Yang
R-H Tian
P2860cites workValidating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortalityQ24745996
Nut consumption and risk of cancer and type 2 diabetes: a systematic review and meta-analysisQ26852156
Global cancer statistics, 2012Q27860501
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statementQ27860537
Measuring inconsistency in meta-analysesQ27860655
Meta-analysis in clinical trialsQ27860779
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chainQ29615210
Diabetes, insulin use, and cancer risk: are observational studies part of the solution-or part of the problem?Q33803413
Associations of hyperglycemia and insulin usage with the risk of cancer in type 2 diabetes: the Hong Kong diabetes registryQ33803499
Significantly increased risk of cancer in patients with diabetes mellitus: a systematic review and meta-analysis.Q33859224
Metformin may function as anti-cancer agent via targeting cancer stem cells: the potential biological significance of tumor-associated miRNAs in breast and pancreatic cancersQ34357952
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.Q34506457
The complexities of obesity and diabetes with the development and progression of pancreatic cancerQ34669361
Immune-mediated antitumor effect by type 2 diabetes drug, metforminQ35089957
Survival of patients with stage IV lung cancer with diabetes treated with metforminQ35153493
Meta-analysis, funnel plots and sensitivity analysisQ35204707
Impact of metformin use on survival in locally-advanced, inoperable non-small cell lung cancer treated with definitive chemoradiationQ35290403
Metformin: multi-faceted protection against cancerQ35764409
Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related MortalityQ35817986
Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancerQ35819793
Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancerQ36140955
Therapy insight: Influence of type 2 diabetes on the development, treatment and outcomes of cancerQ36303910
The effect of metformin and thiazolidinedione use on lung cancer in diabeticsQ36453693
The use of metformin and the incidence of lung cancer in patients with type 2 diabetesQ36477885
Metformin and neoplasia: implications and indicationsQ37933592
Metformin does not alter the risk of lung cancer: a case-control analysis.Q38430462
Prognosis of small cell lung cancer patients with diabetes treated with metforminQ40847551
Metformin use improves the survival of diabetic combined small-cell lung cancer patientsQ40930334
Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy responseQ44362277
Antidiabetes drugs correlate with decreased risk of lung cancer: a population-based observation in TaiwanQ44665632
P433issue6
P921main subjecttype 2 diabetesQ3025883
meta-analysisQ815382
metforminQ19484
lung cancerQ47912
P304page(s)641-649
P577publication date2015-10-12
P1433published inClinical and Translational OncologyQ15754324
P1476titleEffects of metformin on survival outcomes of lung cancer patients with type 2 diabetes mellitus: a meta-analysis
P478volume18

Reverse relations

cites work (P2860)
Q90192600A Cohort Study of Exposure to Antihyperglycemic Therapy and Survival in Patients with Lung Cancer
Q50000289Antitumor effects of metformin via indirect inhibition of protein phosphatase 2A in patients with endometrial cancer.
Q55177909Effect of hypoglycemic agents on survival outcomes of lung cancer patients with diabetes mellitus: A meta-analysis.
Q39040854Hyperglycaemia Induced by Novel Anticancer Agents: An Undesirable Complication or a Potential Therapeutic Opportunity?
Q61455695Impact of metformin use on survival outcomes in non-small cell lung cancer treated with platinum
Q58728734Metabolic Profiles Associated With Metformin Efficacy in Cancer
Q39714372Metformin Use Is Associated with Improved Survival in Patients Undergoing Resection for Pancreatic Cancer
Q91598281Metformin mediated microRNA-7 upregulation inhibits growth, migration, and invasion of non-small cell lung cancer A549 cells
Q37376577Metformin therapy associated with survival benefit in lung cancer patients with diabetes
Q36103093Metformin use and its effect on survival in diabetic patients with advanced non-small cell lung cancer
Q103826245Metformin use and lung cancer survival: a population-based study in Norway
Q38695734Repurposing metformin for the prevention of cancer and cancer recurrence
Q64286784Senolytics and senostatics as adjuvant tumour therapy
Q47769995Targeting Hypoxia to Improve Non-Small Cell Lung Cancer Outcome
Q90541158The prognostic value of metformin for advanced non-small cell lung cancer: a systematic review and meta-analysis
Q38930166Tyrosine Kinase Inhibitor-Induced Interstitial Lung Disease: Clinical Features, Diagnostic Challenges, and Therapeutic Dilemmas