Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer

scientific article published on 22 September 2011

Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/CNCR.26492
P932PMC publication ID3298843
P698PubMed publication ID21952750
P5875ResearchGate publication ID51667522

P50authorWaun Ki HongQ17198867
Scott LippmanQ28112995
Ignacio I WistubaQ74766086
P2093author name stringJ Jack Lee
Ho-Young Lee
Jin-Soo Kim
Carmen Behrens
Edward S Kim
Diane Liu
Luisa Solis
P2860cites workHigh expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507)Q28476277
Lung cancerQ29615473
Oncogenic pathway signatures in human cancers as a guide to targeted therapiesQ29615526
Insulin and insulin-like growth factor signalling in neoplasiaQ29619495
Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lungQ33531781
Insulin-like growth factor receptor 1 (IGF1R) gene copy number is associated with survival in operable non-small-cell lung cancer: a comparison between IGF1R fluorescent in situ hybridization, protein expression, and mRNA expressionQ33813730
Inhibition of cancer cell proliferation and metastasis by insulin receptor downregulationQ33818935
Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapyQ33934670
Molecular Analysis of Non–Small Cell Lung Cancer Identifies Subsets with Different Sensitivity to Insulin-like Growth Factor I Receptor InhibitionQ34187898
Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysisQ34845451
Physical and functional interaction between polyoma virus middle T antigen and insulin and IGF-I receptors is required for oncogene activation and tumour initiationQ34993028
Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease.Q35002762
The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.Q35622508
Insulin-like growth factor receptor 1 (IGF1R) expression and survival in surgically resected non-small-cell lung cancer (NSCLC) patients.Q35994860
Phosphorylated epidermal growth factor receptor and cyclooxygenase-2 expression in localized non-small cell lung cancerQ36717778
The emerging role of the insulin-like growth factor pathway as a therapeutic target in cancerQ37075569
The insulin-like growth factor pathway in lung cancerQ37231655
Expression of insulin receptor isoform A and insulin-like growth factor-1 receptor in human acute myelogenous leukemia: effect of the dual-receptor inhibitor BMS-536924 in vitroQ37389178
The rationale and development of therapeutic insulin-like growth factor axis inhibition for lung and other cancersQ37562558
The potential role of insulin-like growth factor receptor inhibitors in the treatment of advanced non-small cell lung cancerQ37724259
Targeted therapy in non-small-cell lung cancer--is it becoming a reality?Q37765472
Compensatory insulin receptor (IR) activation on inhibition of insulin-like growth factor-1 receptor (IGF-1R): rationale for cotargeting IGF-1R and IR in cancerQ39647932
Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma.Q39877535
Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival.Q39906003
Insulin receptor expression by human prostate cancersQ39941083
Down-regulation of type I insulin-like growth factor receptor increases sensitivity of breast cancer cells to insulin.Q40185322
In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417.Q40333087
Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: implications for cellular potency and selectivity over insulin receptorQ42834919
Prognostic role of insulin-like growth factor receptor-1 expression in small cell lung cancerQ43192989
Prediction of recurrence-free survival in postoperative non-small cell lung cancer patients by using an integrated model of clinical information and gene expressionQ44571511
Insulin receptor expression and clinical outcome in node-negative breast cancerQ44857623
Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer.Q45950196
Antitumor activity of GSK1904529A, a small-molecule inhibitor of the insulin-like growth factor-I receptor tyrosine kinaseQ46041903
Intracellular presence of insulin and its phosphorylated receptor in non-small cell lung cancer.Q46781616
Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action.Q50678899
The role of insulin receptors and IGF-I receptors in cancer and other diseasesQ81238512
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectlung cancerQ47912
preproinsulinQ7240673
P304page(s)2454-2465
P577publication date2011-09-22
P1433published inCancerQ326041
P1476titlePrognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer
P478volume118

Reverse relations

cites work (P2860)
Q47246743A 16-gene expression signature to distinguish stage I from stage II lung squamous carcinoma
Q90192600A Cohort Study of Exposure to Antihyperglycemic Therapy and Survival in Patients with Lung Cancer
Q52682466A Randomized Phase II Study of Metformin plus Paclitaxel/Carboplatin/Bevacizumab in Patients with Chemotherapy-Naïve Advanced or Metastatic Nonsquamous Non-Small Cell Lung Cancer.
Q28731874A novel classification of lung cancer into molecular subtypes
Q37105231A twenty-first century cancer epidemic caused by obesity: the involvement of insulin, diabetes, and insulin-like growth factors
Q36140955Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer
Q42218166Association of IGF1R polymorphisms with the development of HBV-related hepatocellular carcinoma
Q35123145Differential expression of the insulin-like growth factor receptor among early breast cancer subtypes
Q35803926Effects of metformin on survival outcomes of lung cancer patients with type 2 diabetes mellitus: a meta-analysis
Q61455101Epithelial insulin receptor expression-prognostic relevance in colorectal cancer
Q47988612Expression of small leucine-rich extracellular matrix proteoglycans biglycan and lumican reveals oral lichen planus malignant potential
Q99248451Hyperinsulinaemia in cancer
Q44518083IGF-1R and Bmi-1 expressions in lung adenocarcinoma and their clinicopathologic and prognostic significance
Q35103273Increased IR-A/IR-B ratio in non-small cell lung cancers associates with lower epithelial-mesenchymal transition signature and longer survival in squamous cell lung carcinoma
Q33822523Insulin receptor expression in clear cell renal cell carcinoma and its relation to prognosis
Q38883620Insulin, insulin receptors, and cancer.
Q38663388Insulin-like Growth Factor 1 Receptor Expression in Advanced Non-small-cell Lung Cancer and its Impact on Overall Survival
Q34568232Insulin-like growth factor 1 receptor (IGF1R) expression and survival in operable squamous-cell laryngeal cancer
Q34501591Insulin-like growth factor receptor 1 (IGF1R) expression and survival in non-small cell lung cancer patients: a meta-analysis.
Q53525637Insulin-like growth factor-1 receptor is associated with better prognosis in classical Hodgkin's lymphoma: Correlation with MET expression.
Q37151297Metformin Enhances the Therapy Effects of Anti-IGF-1R mAb Figitumumab to NSCLC.
Q36103093Metformin use and its effect on survival in diabetic patients with advanced non-small cell lung cancer
Q47700884Oncogenic activity of insulin in the development of non-small cell lung carcinoma
Q36922072Overexpression of Insulin-like Growth Factor-1 Receptor Is Associated With Penile Cancer Progression
Q38395821Phosphorylated insulin-like growth factor-1 receptor (pIGF1R) is a poor prognostic factor in brain metastases from lung adenocarcinomas
Q33599090Prediction of survival in resected non-small cell lung cancer using a protein expression-based risk model: implications for personalized chemoprevention and therapy
Q39324387Prognostic impact of Raf-1 and p-Raf-1 expressions for poor survival rate in non-small cell lung cancer
Q36066604Prognostic implications of tumoral expression of insulin like growth factors 1 and 2 in patients with non-small-cell lung cancer
Q64898408Prognostic value of IGF-1R in lung cancer: A PRISMA-compliant meta-analysis.
Q35153493Survival of patients with stage IV lung cancer with diabetes treated with metformin
Q37650665TGFBI expression is an independent predictor of survival in adjuvant-treated lung squamous cell carcinoma patients
Q35677049Targeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer
Q93118229The expression of the insulin receptor in gastric cancer correlates with the HER2 status and may have putative therapeutic implications
Q37984217The insulin and insulin-like growth factor receptor family in neoplasia: an update
Q26852910The links between insulin resistance, diabetes, and cancer
Q49986742The preoperative HbA1c level is an independent prognostic factor for the postoperative survival after resection of non-small cell lung cancer in elderly patients
Q37315146The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells
Q26798408Understanding the Key to Targeting the IGF Axis in Cancer: A Biomarker Assessment
Q55434033[The targets research of non-small cell lung cancer targeted therapy].

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