| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Olaf Witt | |
| Ina Oehme | |||
| Emily Koeneke | |||
| P2860 | cites work | Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors | Q79905248 |
| The role of autophagy in mitochondria maintenance: characterization of mitochondrial functions in autophagy-deficient S. cerevisiae strains | Q80088521 | ||
| P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells | Q84225051 | ||
| A substrate-independent TR-FRET histone deacetylase inhibitor assay | Q84975341 | ||
| Guidelines for the use and interpretation of assays for monitoring autophagy | Q21996341 | ||
| Hallmarks of Cancer: The Next Generation | Q22252312 | ||
| Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor | Q22253464 | ||
| Molecular cloning and characterization of a novel histone deacetylase HDAC10 | Q24291945 | ||
| Isolation and characterization of a novel class II histone deacetylase, HDAC10 | Q24291980 | ||
| Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain | Q24292353 | ||
| Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family | Q24294179 | ||
| HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle | Q24296105 | ||
| HDAC6 is a microtubule-associated deacetylase | Q24298013 | ||
| The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress | Q24301895 | ||
| HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor | Q24303612 | ||
| Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy | Q24311582 | ||
| HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin | Q24337155 | ||
| Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes | Q24338109 | ||
| Histone deacetylases (HDACs): characterization of the classical HDAC family | Q24535587 | ||
| Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor | Q24569647 | ||
| Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy | Q24603793 | ||
| Pyridylalanine-containing hydroxamic acids as selective HDAC6 inhibitors | Q39904164 | ||
| Suberoylanilide hydroxamic acid (SAHA) induces apoptosis or autophagy-associated cell death in chondrosarcoma cell lines. | Q39960970 | ||
| HDAC10 promoter polymorphism associated with development of HCC among chronic HBV patients | Q40076803 | ||
| LC3B-II deacetylation by histone deacetylase 6 is involved in serum-starvation-induced autophagic degradation. | Q41923498 | ||
| Induction of autophagy in malignant rhabdoid tumor cells by the histone deacetylase inhibitor FK228 through AIF translocation. | Q41940127 | ||
| HDACs link the DNA damage response, processing of double-strand breaks and autophagy | Q41979339 | ||
| Developmental expression of histone deacetylase 11 in the murine brain | Q42071643 | ||
| Autophagy-deficient mice develop multiple liver tumors | Q42099409 | ||
| HDAC isoenzyme expression is deregulated in chronic lymphocytic leukemia B-cells and has a complex prognostic significance | Q42426152 | ||
| Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors | Q42555454 | ||
| An unbiased approach to identify endogenous substrates of "histone" deacetylase 8. | Q42949453 | ||
| Inhibition of histone deacetylase1 induces autophagy | Q46700670 | ||
| HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth | Q48227278 | ||
| Discovery of the first histone deacetylase 6/8 dual inhibitors. | Q50995611 | ||
| Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors. | Q52564601 | ||
| A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance. | Q54270777 | ||
| Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene | Q24617547 | ||
| The PEA-15 protein regulates autophagy via activation of JNK | Q24618100 | ||
| The many roles of histone deacetylases in development and physiology: implications for disease and therapy | Q24628821 | ||
| Epigenetic control of skull morphogenesis by histone deacetylase 8 | Q24646214 | ||
| Self-consumption: the interplay of autophagy and apoptosis | Q26828473 | ||
| Autophagy modulation as a potential therapeutic target for diverse diseases | Q27010076 | ||
| Mechanisms of mitophagy | Q27310261 | ||
| Autophagy in the Pathogenesis of Disease | Q27860558 | ||
| Lysine acetylation targets protein complexes and co-regulates major cellular functions | Q27860589 | ||
| Autophagy fights disease through cellular self-digestion | Q27860902 | ||
| Induction of autophagy and inhibition of tumorigenesis by beclin 1 | Q28131718 | ||
| Mutational analyses of WNT7A and HDAC11 as candidate tumour suppressor genes in sporadic malignant pancreatic endocrine tumours | Q28281731 | ||
| Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug | Q28282479 | ||
| microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia | Q28284121 | ||
| Development of a histone deacetylase 6 inhibitor and its biological effects | Q28298272 | ||
| To be or not to be? How selective autophagy and cell death govern cell fate | Q28385846 | ||
| Autophagy inhibition promotes 5-fluorouraci-induced apoptosis by stimulating ROS formation in human non-small cell lung cancer A549 cells | Q28486234 | ||
| Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis | Q28505748 | ||
| Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10 | Q28509194 | ||
| HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo | Q28510434 | ||
| Histone deacetylase 11 regulates oligodendrocyte-specific gene expression and cell development in OL-1 oligodendroglia cells | Q28580239 | ||
| Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability. | Q28585375 | ||
| Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development | Q28592216 | ||
| Isolation and characterization of mammalian HDAC10, a novel histone deacetylase | Q28594682 | ||
| Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice | Q29615615 | ||
| Anticancer activities of histone deacetylase inhibitors | Q29616624 | ||
| The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men | Q29619117 | ||
| Autophagy in human health and disease | Q29620121 | ||
| Pancreatic cancers require autophagy for tumor growth | Q29620331 | ||
| HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy | Q30014829 | ||
| Molecular mechanisms of ATP secretion during immunogenic cell death | Q30408773 | ||
| HDAC6 modulates cell motility by altering the acetylation level of cortactin | Q30439626 | ||
| A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. | Q35976663 | ||
| HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells. | Q36028506 | ||
| Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control | Q36639688 | ||
| Reversible acetylation regulates salt-inducible kinase (SIK2) and its function in autophagy | Q36647258 | ||
| Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy | Q36799136 | ||
| Deconvoluting the context-dependent role for autophagy in cancer | Q36876716 | ||
| Histone deacetylase 10 promotes autophagy-mediated cell survival. | Q37010515 | ||
| Histone deacetylase (HDAC) 10 suppresses cervical cancer metastasis through inhibition of matrix metalloproteinase (MMP) 2 and 9 expression | Q37201244 | ||
| HDAC family: What are the cancer relevant targets? | Q37281991 | ||
| Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment | Q37299613 | ||
| HDAC expression and clinical prognosis in human malignancies | Q37356662 | ||
| Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling | Q37379390 | ||
| Strange attractors: DAMPs and autophagy link tumor cell death and immunity | Q37424115 | ||
| Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide | Q37468827 | ||
| Proliferative status regulates HDAC11 mRNA abundance in nontransformed fibroblasts | Q37492319 | ||
| Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies | Q37616407 | ||
| Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy | Q37626910 | ||
| Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. | Q37700043 | ||
| Autophagy is a therapeutic target in anticancer drug resistance. | Q37773489 | ||
| Chemical modulators of autophagy as biological probes and potential therapeutics | Q37821750 | ||
| The role of autophagy in cancer: therapeutic implications | Q37924056 | ||
| Sirtuins' modulation of autophagy | Q38108575 | ||
| Autophagy-mediated regulation of macrophages and its applications for cancer. | Q38168389 | ||
| Cracking the survival code: autophagy-related histone modifications | Q38178832 | ||
| Therapeutic potential of histone deacetylase inhibitors in pancreatic cancer | Q38188692 | ||
| Autophagy in antimicrobial immunity | Q38207186 | ||
| Autophagy and cancer metabolism | Q38214981 | ||
| Cargo recognition and trafficking in selective autophagy | Q38215949 | ||
| Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders | Q38240733 | ||
| Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation | Q38344102 | ||
| Induction of autophagy counteracts the anticancer effect of cisplatin in human esophageal cancer cells with acquired drug resistance | Q38955141 | ||
| Inhibition of autophagy enhances the radiosensitivity of nasopharyngeal carcinoma by reducing Rad51 expression | Q38961246 | ||
| Eradication of metastatic melanoma through cooperative expression of RNA-based HDAC1 inhibitor and p73 by oncolytic adenovirus | Q38970754 | ||
| CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation | Q39018985 | ||
| p53 status determines the role of autophagy in pancreatic tumour development | Q39048945 | ||
| Inhibition of autophagy induced by TSA sensitizes colon cancer cell to radiation | Q39079713 | ||
| BAG3 induction is required to mitigate proteotoxicity via selective autophagy following inhibition of constitutive protein degradation pathways | Q39156205 | ||
| Outcome of early clinical trials of the combination of hydroxychloroquine with chemotherapy in cancer | Q39165398 | ||
| DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions | Q39271550 | ||
| ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner | Q39285023 | ||
| Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation | Q39353049 | ||
| Combination of pan-histone deacetylase inhibitor and autophagy inhibitor exerts superior efficacy against triple-negative human breast cancer cells | Q39389718 | ||
| Autophagy activation in hepatocellular carcinoma contributes to the tolerance of oxaliplatin via reactive oxygen species modulation | Q39493222 | ||
| Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors | Q39630633 | ||
| Inhibition of Histone Deacetylase 10 Induces Thioredoxin-Interacting Protein and Causes Accumulation of Reactive Oxygen Species in SNU-620 Human Gastric Cancer Cells | Q39672379 | ||
| The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib | Q39856430 | ||
| Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction | Q30559284 | ||
| Chemical phylogenetics of histone deacetylases | Q30977637 | ||
| A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme | Q33416266 | ||
| Histone deacetylase 10 relieves repression on the melanogenic program by maintaining the deacetylation status of repressors | Q33748031 | ||
| Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma | Q33854012 | ||
| Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy | Q33920232 | ||
| Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia. | Q34038766 | ||
| Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines | Q34132803 | ||
| HDAC1 inactivation induces mitotic defect and caspase-independent autophagic cell death in liver cancer | Q34230019 | ||
| Histone deacetylases and cancer. | Q34298745 | ||
| Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients. | Q34340318 | ||
| Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma | Q34372972 | ||
| Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors | Q34372994 | ||
| HDAC11 is a novel drug target in carcinomas. | Q34424846 | ||
| Chromosomal organization and localization of the novel class IV human histone deacetylase 11 gene | Q34448419 | ||
| Histone deacetylases and cancer: causes and therapies | Q34570082 | ||
| Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function | Q34616226 | ||
| Histone deacetylases 9 and 10 are required for homologous recombination | Q34624058 | ||
| Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. | Q34626763 | ||
| Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors | Q34687445 | ||
| A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas | Q34747237 | ||
| Principles and current strategies for targeting autophagy for cancer treatment | Q34787732 | ||
| Histone deacetylase 8 in neuroblastoma tumorigenesis | Q34913307 | ||
| Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells | Q35096555 | ||
| Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy | Q35109281 | ||
| Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis | Q35128818 | ||
| HDAC6 deacetylates Ku70 and regulates Ku70-Bax binding in neuroblastoma | Q35166324 | ||
| Histone deacetylase HDAC4 promotes gastric cancer SGC-7901 cells progression via p21 repression. | Q35181361 | ||
| Autophagy: a regulated bulk degradation process inside cells | Q35610897 | ||
| Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice | Q35749672 | ||
| Receptor proteins in selective autophagy | Q35872411 | ||
| Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility | Q35893654 | ||
| Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma | Q35915726 | ||
| Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death | Q35922012 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 2 | |
| P921 | main subject | autophagy | Q288322 |
| P304 | page(s) | 135-168 | |
| P577 | publication date | 2015-04-23 | |
| P1433 | published in | Cells | Q27724621 |
| P1476 | title | HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities | |
| P478 | volume | 4 |
| Q55692299 | Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance. |
| Q89951520 | Endoplasmic Reticulum Stress Signaling in Cancer Cells |
| Q60907794 | Epigenetic Targeting of Autophagy via HDAC Inhibition in Tumor Cells: Role of p53 |
| Q58698660 | Gene expression profile of human lung in a relatively early stage of COPD with emphysema |
| Q90334452 | HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1 |
| Q38947405 | HDACs and HDAC Inhibitors in Cancer Development and Therapy |
| Q47136872 | Histone Deacetylase Inhibitor-Induced Autophagy in Tumor Cells: Implications for p53. |
| Q58768571 | Histone deacetylase 6 in cancer |
| Q52689154 | Histone deacetylase inhibitor ITF2357 leads to apoptosis and enhances doxorubicin cytotoxicity in preclinical models of human sarcoma. |
| Q92612020 | Histone deacetylase inhibitors dysregulate DNA repair proteins and antagonize metastasis-associated processes |
| Q92445781 | Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced Autophagy |
| Q48163206 | Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa. |
| Q90632680 | Role of Histone Deacetylases in Carcinogenesis: Potential Role in Cholangiocarcinoma |
| Q93238128 | Targeted therapy for mTORC1-driven tumours through HDAC inhibition by exploiting innate vulnerability of mTORC1 hyper-activation |
| Q38826740 | Targeting histone deacetylase 8 as a therapeutic approach to cancer and neurodegenerative diseases |
| Q64389399 | The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines |
| Q59328957 | The Role of Autophagy in iNKT Cell Development |
| Q47722579 | The uncoupling of autophagy and zinc homeostasis in airway epithelial cells as a fundamental contributor to COPD. |
| Q41168233 | Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance |
| Q47162428 | Vorinostat and metformin sensitize EGFR-TKI resistant NSCLC cells via BIM-dependent apoptosis induction |
| Q92083193 | p53 at the Crossroads between Different Types of HDAC Inhibitor-Mediated Cancer Cell Death |
| Q52645040 | p53-Mediated Molecular Control of Autophagy in Tumor Cells. |
Search more.