scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1000022454 |
P356 | DOI | 10.1186/1868-7083-4-5 |
P2888 | exact match | https://scigraph.springernature.com/pub.10.1186/1868-7083-4-5 |
P932 | PMC publication ID | 3320549 |
P698 | PubMed publication ID | 22414492 |
P5875 | ResearchGate publication ID | 221892453 |
P2093 | author name string | James R Davie | |
Dilshad H Khan | |||
Geneviève P Delcuve | |||
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Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR | Q24292197 | ||
HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription | Q24292915 | ||
Differential distribution of unmodified and phosphorylated histone deacetylase 2 in chromatin | Q24293063 | ||
SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing | Q24298821 | ||
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The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation | Q24650204 | ||
Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis | Q24656948 | ||
Negative and positive regulation of gene expression by mouse histone deacetylase 1 | Q24672508 | ||
A role for histone deacetylase activity in HDAC1-mediated transcriptional repression | Q24682567 | ||
Dynamic acetylation of all lysine 4-methylated histone H3 in the mouse nucleus: analysis at c-fos and c-jun | Q24814990 | ||
Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors | Q27619648 | ||
Lysine acetylation targets protein complexes and co-regulates major cellular functions | Q27860589 | ||
Chromatin modifications and their function | Q27861067 | ||
Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription | Q27932406 | ||
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex | Q27935315 | ||
MAPK-regulated transcription: a continuously variable gene switch? | Q28217211 | ||
Regulating the regulators: the post-translational code of class I HDAC1 and HDAC2. | Q37825437 | ||
HDAC6 α-tubulin deacetylase: a potential therapeutic target in neurodegenerative diseases | Q37850047 | ||
MicroRNAs and epigenetics | Q37852129 | ||
The central role of RNA in human development and cognition | Q37873983 | ||
Beyond corticosteroids: future prospects in the management of inflammation in COPD. | Q37924451 | ||
Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression | Q39247455 | ||
Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions | Q39408797 | ||
Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide | Q39430288 | ||
SRSF2 is required for sodium butyrate-mediated p21(WAF1) induction and premature senescence in human lung carcinoma cell lines | Q39545604 | ||
A novel mammalian complex containing Sin3B mitigates histone acetylation and RNA polymerase II progression within transcribed loci | Q39637279 | ||
Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans. | Q39681612 | ||
Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex | Q39742002 | ||
Promoter chromatin remodeling of immediate-early genes is mediated through H3 phosphorylation at either serine 28 or 10 by the MSK1 multi-protein complex | Q39744187 | ||
Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation | Q39790803 | ||
Epigenetic regulation of microRNA expression in colorectal cancer | Q39838959 | ||
Suberoylanilide hydroxamic acid (SAHA) changes microRNA expression profiles in A549 human non-small cell lung cancer cells | Q39840260 | ||
miR-449a targets HDAC-1 and induces growth arrest in prostate cancer | Q39878284 | ||
Effect of trichostatin a on viability and microRNA expression in human pancreatic cancer cell line BxPC-3. | Q39900934 | ||
Competitive inhibition of histone deacetylase activity by trichostatin A and butyrate | Q40039538 | ||
The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells | Q40308810 | ||
Rapid alteration of microRNA levels by histone deacetylase inhibition | Q40322140 | ||
Multiple alternate p21 transcripts are regulated by p53 in human cells. | Q40356042 | ||
Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1. | Q40812791 | ||
A phosphorylation switch regulates the transcriptional activation of cell cycle regulator p21 by histone deacetylase inhibitors. | Q41198504 | ||
Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis. | Q42757408 | ||
Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation | Q43767926 | ||
Histone deacetylase 1 inactivation by an adenovirus early gene product. | Q43950174 | ||
Regulation of histone deacetylase 2 by protein kinase CK2. | Q44039963 | ||
Chromatin: the final frontier in splicing regulation? | Q45933227 | ||
Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice. | Q47267690 | ||
Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis. | Q47860803 | ||
Combined Action of PHD and Chromo Domains Directs the Rpd3S HDAC to Transcribed Chromatin | Q58422628 | ||
Effects of histone acetylation on the solubility and folding of the chromatin fiber | Q73694438 | ||
Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells | Q81207981 | ||
HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention | Q28240437 | ||
The human Mi-2/NuRD complex and gene regulation | Q28240457 | ||
Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes | Q28255974 | ||
An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation | Q28265681 | ||
Regulation of LSD1 histone demethylase activity by its associated factors | Q28270391 | ||
Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs | Q28291487 | ||
Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development | Q28508648 | ||
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity | Q28508698 | ||
Histone H4-K16 acetylation controls chromatin structure and protein interactions | Q29614521 | ||
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux | Q29615102 | ||
New nomenclature for chromatin-modifying enzymes | Q29616425 | ||
Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter | Q29616537 | ||
Epigenetics in cancer | Q29617139 | ||
Linking DNA methylation and histone modification: patterns and paradigms | Q29617801 | ||
Functions of site-specific histone acetylation and deacetylation | Q29617894 | ||
The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men | Q29619117 | ||
Acetylation and deacetylation of non-histone proteins | Q29619636 | ||
Histone acetyltransferase complexes: one size doesn't fit all | Q29620006 | ||
Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly | Q30431647 | ||
Chemical phylogenetics of histone deacetylases | Q30977637 | ||
Histone deacetylase inhibitors: a chemical genetics approach to understanding cellular functions | Q33705588 | ||
Transcription factor co-repressors in cancer biology: roles and targeting | Q33762000 | ||
Disruption of higher-order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III | Q33775383 | ||
Histone deacetylase activity modulates alternative splicing. | Q33818140 | ||
Differential intranuclear organization of transcription factors Sp1 and Sp3. | Q33938359 | ||
Quantitative proteomics identify novel miR-155 target proteins. | Q33974878 | ||
Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression | Q34088777 | ||
Hdac3 is essential for the maintenance of chromatin structure and genome stability | Q34417264 | ||
Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans | Q34488391 | ||
Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy. | Q34488424 | ||
HDAC activity is required for efficient core promoter function at the mouse mammary tumor virus promoter | Q34495315 | ||
Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1). | Q34520098 | ||
Dynamic histone acetylation is critical for cotranscriptional spliceosome assembly and spliceosomal rearrangements | Q34549852 | ||
The biology of lysine acetylation integrates transcriptional programming and metabolism | Q34692752 | ||
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. | Q34712578 | ||
A shifting paradigm: histone deacetylases and transcriptional activation | Q34725666 | ||
HDAC6: a key regulator of cytoskeleton, cell migration and cell-cell interactions | Q34778023 | ||
How epigenetics can explain human metastasis: a new role for microRNAs | Q34932080 | ||
Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner | Q35202794 | ||
Activity-based probes for proteomic profiling of histone deacetylase complexes | Q35611605 | ||
Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility | Q35893654 | ||
Sin3: a flexible regulator of global gene expression and genome stability. | Q35964130 | ||
Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1 | Q36017473 | ||
Enhanced histone acetylation and transcription: a dynamic perspective | Q36555220 | ||
Chromatin challenges during DNA replication and repair | Q36744476 | ||
Closed chromatin architecture is induced by an RNA duplex targeting the HIV-1 promoter region | Q36838738 | ||
Class IIa histone deacetylases: regulating the regulators | Q36908414 | ||
MicroRNA-directed transcriptional gene silencing in mammalian cells | Q36945167 | ||
Cross-regulation of histone modifications | Q36994157 | ||
Nuclear organization and chromatin dynamics--Sp1, Sp3 and histone deacetylases | Q37054507 | ||
Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke | Q37139659 | ||
Role of HDAC2 in the pathophysiology of COPD. | Q37279332 | ||
HDAC family: What are the cancer relevant targets? | Q37281991 | ||
Histone deacetylase inhibitors: anticancer compounds | Q37290570 | ||
Eloquent silence: developmental functions of Class I histone deacetylases | Q37302011 | ||
Histone deacetylases: salesmen and customers in the post-translational modification market. | Q37389553 | ||
Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders. | Q37438513 | ||
Trans-regulation of histone deacetylase activities through acetylation | Q37454297 | ||
Histone deacetylase HDAC1/HDAC2-controlled embryonic development and cell differentiation | Q37468782 | ||
Class IIa histone deacetylases: conducting development and differentiation | Q37468789 | ||
Histone deacetylases and the immunological network: implications in cancer and inflammation | Q37621256 | ||
Transcriptional regulation by promoter targeted RNAs | Q37622413 | ||
Deconstructing repression: evolving models of co-repressor action | Q37677559 | ||
Inside HDAC with HDAC inhibitors | Q37707623 | ||
Regulatory signal transduction pathways for class IIa histone deacetylases | Q37744144 | ||
Interplay between microRNAs and the epigenetic machinery: an intricate network | Q37759740 | ||
Controlling transcription with noncoding RNAs in mammalian cells | Q37766911 | ||
Molecular mechanisms of oxidative stress in airways and lungs with reference to asthma and chronic obstructive pulmonary disease. | Q37780591 | ||
Physiological roles of class I HDAC complex and histone demethylase. | Q37806964 | ||
HDACi--going through the mechanisms | Q37825145 | ||
P433 | issue | 1 | |
P304 | page(s) | 5 | |
P577 | publication date | 2012-03-12 | |
P1433 | published in | Clinical Epigenetics | Q18620113 |
P1476 | title | Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors | |
P478 | volume | 4 |
Q37040116 | A Role for Nuclear Actin in HDAC 1 and 2 Regulation |
Q34990282 | A comprehensive view of the epigenetic landscape. Part II: Histone post-translational modification, nucleosome level, and chromatin regulation by ncRNAs |
Q40138443 | Alterations of Nuclear Architecture and Epigenetic Signatures during African Swine Fever Virus Infection |
Q52321520 | Analysis of Human Nuclear Protein Complexes by Quantitative Mass Spectrometry Profiling. |
Q38895546 | Anti-fibrotic effects of valproic acid: role of HDAC inhibition and associated mechanisms |
Q37633285 | Anti-leukemia effects of the novel synthetic 1-benzylindole derivative 21-900 in vitro and in vivo |
Q92457798 | Atherosclerosis and flow: roles of epigenetic modulation in vascular endothelium |
Q46740626 | Bisphenol A deteriorates egg quality through HDAC7 suppression. |
Q47598678 | Bivalent complexes of PRC1 with orthologs of BRD4 and MOZ/MORF target developmental genes in Drosophila. |
Q42370737 | CRISPR-mediated HDAC2 disruption identifies two distinct classes of target genes in human cells |
Q41930612 | Canonical and Non-Canonical Autophagy in HIV-1 Replication Cycle |
Q54259387 | Capsaicin upregulates HDAC2 via TRPV1 and impairs neuronal maturation in mice. |
Q47181318 | Changes in DNA methylation induced by multi-walled carbon nanotube exposure in the workplace. |
Q41536919 | Chaperone co-inducer BGP-15 inhibits histone deacetylases and enhances the heat shock response through increased chromatin accessibility |
Q92565466 | Chemical screen for epigenetic barriers to single allele activation of Oct4 |
Q47117370 | Cinnamaldehyde, Cinnamic Acid, and Cinnamyl Alcohol, the Bioactives of Cinnamomum cassia Exhibit HDAC8 Inhibitory Activity: An In vitro and In silico Study. |
Q34353711 | Class I HDAC imaging using [ (3)H]CI-994 autoradiography |
Q36963704 | Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc |
Q48194888 | Class I histone deacetylase inhibition improves pancreatitis outcome by limiting leukocyte recruitment and acinar-to-ductal metaplasia |
Q91588484 | Comparison of Radiosensitization by HDAC Inhibitors CUDC-101 and SAHA in Pancreatic Cancer Cells |
Q64110985 | Control of viral infections by epigenetic-targeted therapy |
Q47112935 | Coptis Chinensis affects the function of glioma cells through the down-regulation of phosphorylation of STAT3 by reducing HDAC3. |
Q26860240 | Creating a "Prosurvival Phenotype" Through Histone Deacetylase Inhibition: Past, Present, and Future |
Q47996549 | Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine-based Histone Deacetylase Inhibitors |
Q48684051 | Design, Synthesis, and Biological Evaluation of Tetrahydroisoquinoline-Based Histone Deacetylase 8 Selective Inhibitors. |
Q38741165 | Diagnostic and Therapeutic Implications of Histone Epigenetic Modulators in Breast Cancer. |
Q38652105 | Different resuscitation strategies and novel pharmacologic treatment with valproic acid in traumatic brain injury. |
Q52884352 | Differential Response of Human Hepatocyte Chromatin to HDAC Inhibitors as a Function of Microenvironmental Glucose Level. |
Q54259222 | Distinct Roles for Intestinal Epithelial Cell-Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis. |
Q36941144 | Divergent Binding and Transactivation by Two Related Steroid Receptors at the Same Response Element. |
Q38931757 | Diverse Activities of Histone Acylations Connect Metabolism to Chromatin Function |
Q44206409 | Dynamic distribution of HDAC1 and HDAC2 during mitosis: association with F-actin. |
Q38966904 | EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer |
Q38431356 | Emerging approaches for histone deacetylase inhibitor drug discovery |
Q44343064 | Epigenetic Activation of μ-Opioid Receptor Gene via Increased Expression and Function of Mitogen- and Stress-Activated Protein Kinase 1. |
Q26753020 | Epigenetic Control of Macrophage Polarisation and Soluble Mediator Gene Expression during Inflammation |
Q51487802 | Epigenetic Regulation of Cytosolic Phospholipase A2 in SH-SY5Y Human Neuroblastoma Cells. |
Q51453460 | Epigenetic Regulation of SNAP25 Prevents Progressive Glutamate Excitotoxicty in Hypoxic CA3 Neurons. |
Q89850073 | Epigenetic Therapy as a Putative Molecular Target to Modulate B Cell Biology and Behavior in the Context of Immunological Disorders |
Q35835175 | Epigenetic activities of flavonoids in the prevention and treatment of cancer |
Q47925246 | Epigenetic and molecular signatures of cord blood CD34(+) cells treated with histone deacetylase inhibitors |
Q39507029 | Epigenetic mechanisms contribute to the expression of immune related genes in the livers of dairy cows fed a high concentrate diet |
Q33858861 | Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders. |
Q37624477 | Epigenetic regulation and chromatin remodeling in learning and memory |
Q37741012 | Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Aβ toxicity in a mouse model of Alzheimer's disease |
Q38976359 | Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase |
Q40064521 | Epigenetic reprogramming induces the expansion of cord blood stem cells |
Q38742430 | Epigenetics and allergy: from basic mechanisms to clinical applications. |
Q26772330 | Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response |
Q38748410 | Exploring the epigenetic drug discovery landscape |
Q47918598 | Expression of DHA-Metabolizing Enzyme Alox15 is Regulated by Selective Histone Acetylation in Neuroblastoma Cells |
Q28543028 | Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression |
Q37285451 | Flow-induced HDAC1 phosphorylation and nuclear export in angiogenic sprouting. |
Q36178413 | From HDACi to KDACi: we need to revisit non-epigenetic pathways affected by inhibiting lysine deacetylases in therapy |
Q34534169 | Green tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms |
Q35824343 | HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities |
Q36359485 | HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade. |
Q94526741 | HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment |
Q34410902 | HDAC inhibitors as cognitive enhancers in fear, anxiety and trauma therapy: where do we stand? |
Q45331952 | HDAC inhibitors prevent the induction of the immediate-early gene FOSL1, but do not alter the nucleosome response |
Q64105197 | HDAC1 and HDAC2 independently regulate common and specific intrinsic responses in murine enteroids |
Q64954027 | HDAC5 Expression in Urothelial Carcinoma Cell Lines Inhibits Long-Term Proliferation but Can Promote Epithelial-to-Mesenchymal Transition. |
Q61798873 | HDAC6 selective inhibition of melanoma patient T-cells augments anti-tumor characteristics |
Q42321917 | HDAC8 Catalyzes the Hydrolysis of Long Chain Fatty Acyl Lysine. |
Q38265455 | HIV-1 Vpr Protein Induces Proteasomal Degradation of Chromatin-associated Class I HDACs to Overcome Latent Infection of Macrophages. |
Q39807048 | Hepatitis B virus basal core promoter mutations show lower replication fitness associated with cccDNA acetylation status. |
Q91864159 | Heterogeneity in the regenerative abilities of central nervous system axons within species: why do some neurons regenerate better than others? |
Q36146330 | Histone Deacetylases in Bone Development and Skeletal Disorders. |
Q38893201 | Histone Deacetylases in Cartilage Homeostasis and Osteoarthritis |
Q40799410 | Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1 |
Q59795902 | Histone deacetylase 6 expression in metastatic lymph nodes is a valuable prognostic marker for resected node-positive esophageal squamous cell cancer |
Q41581397 | Histone deacetylase 6 structure and molecular basis of catalysis and inhibition |
Q33904495 | Histone deacetylase expression patterns in developing murine optic nerve |
Q47102173 | Histone deacetylase inhibition attenuates hepatic steatosis in rats with experimental Cushing's syndrome |
Q24633763 | Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents |
Q47866992 | Histone deacetylase inhibition, but not a mineralocorticoid receptor antagonist spironolactone, attenuates atypical transcription by an activating mutant MR (MRS 810L ). |
Q34647217 | Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses |
Q41772663 | Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression |
Q38240733 | Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders |
Q38376048 | Histone deacetylation meets miRNA: epigenetics and post-transcriptional regulation in cancer and chronic diseases. |
Q54590480 | Holocarboxylase synthetase acts as a biotin-independent transcriptional repressor interacting with HDAC1, HDAC2 and HDAC7. |
Q39038132 | Identification of NuRSERY, a new functional HDAC complex composed by HDAC5, GATA1, EKLF and pERK present in human erythroid cells |
Q64084407 | Immunopathogenic Mechanisms and Novel Immune-Modulated Therapies in Rheumatoid Arthritis |
Q57842300 | Impaired Mitophagy and Protein Acetylation Levels in Fibroblasts from Parkinson’s Disease Patients |
Q37540019 | Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells |
Q34401887 | Inhibition of DNA methyltransferase activity and expression by treatment with the pan-deacetylase inhibitor panobinostat in hepatocellular carcinoma cell lines |
Q38993736 | Inhibition of histone deacetylases in melanoma-a perspective from bench to bedside |
Q38833038 | Inhibitors of enzymes catalyzing modifications to histone lysine residues: structure, function and activity |
Q41268048 | Low Concentration of Sodium Butyrate from Ultrabraid+NaBu suture, Promotes Angiogenesis and Tissue Remodelling in Tendon-bones Injury |
Q38739403 | Low-dose radiation differentially regulates protein acetylation and histone deacetylase expression in human coronary artery endothelial cells |
Q48098684 | Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics. |
Q89893356 | Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex |
Q27015931 | Mechanisms of Histone Deacetylase Inhibitor-Regulated Gene Expression in Cancer Cells |
Q28539371 | MicroRNA profiling as tool for in vitro developmental neurotoxicity testing: the case of sodium valproate |
Q36572465 | MicroRNA-feedback loop as a key modulator of liver tumorigenesis and inflammation. |
Q38133419 | MicroRNAs: potential regulators of renal development genes that contribute to CAKUT. |
Q35884595 | Microarray gene expression profiling reveals potential mechanisms of tumor suppression by the class I HDAC-selective benzoylhydrazide inhibitors. |
Q88639175 | More than a powerplant: the influence of mitochondrial transfer on the epigenome |
Q89517413 | Mutual balance of histone deacetylases HDAC1, HDAC2, and the acetyl reader ATAD2 regulates the level of acetylation of histone H4 on nascent chromatin of human cells |
Q38938284 | Mycobacterium tuberculosis Infection Induces HDAC1-Mediated Suppression of IL-12B Gene Expression in Macrophages |
Q39309715 | NF-κBp50 and HDAC1 Interaction Is Implicated in the Host Tolerance to Infection Mediated by the Bacterial Quorum Sensing Signal 2-Aminoacetophenone. |
Q35182763 | NFAT1 and NFAT3 cooperate with HDAC4 during regulation of alternative splicing of PMCA isoforms in PC12 cells |
Q37384519 | NLRP12 modulates host defense through IL-17A-CXCL1 axis |
Q92074484 | Nerve-mediated expression of histone deacetylases regulates limb regeneration in axolotls |
Q47136602 | Network of phosphatases and HDAC complexes at repressed chromatin |
Q55717745 | Neutralizing negative epigenetic regulation by HDAC5 enhances human haematopoietic stem cell homing and engraftment. |
Q51584555 | Novel SAHA analogues inhibit HDACs, induce apoptosis and modulate the expression of microRNAs in hepatocellular carcinoma. |
Q34494941 | Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon |
Q49610036 | Nuclear Lipid Mediators: Role of Nuclear Sphingolipids and Sphinosine-1-Phosphate Signaling in Epigenetic Regulation of Inflammation and Gene Expression. |
Q48144118 | Nucleoporins redistribute inside the nucleus after cell cycle arrest induced by histone deacetylases inhibition |
Q35832313 | Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy |
Q42123491 | Oxidative stress signaling to chromatin in health and disease. |
Q57174535 | PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart |
Q38835113 | Panobinostat for the treatment of acute myelogenous leukemia |
Q39051488 | Phenotypic impact of deregulated expression of class I histone deacetylases in urothelial cell carcinoma of the bladder. |
Q34401375 | Prenatal caloric restriction enhances DNA methylation and MeCP2 recruitment with reduced murine placental glucose transporter isoform 3 expression |
Q90426558 | Proteasome inhibitor induced SIRT1 deacetylates GLI2 to enhance hedgehog signaling activity and drug resistance in multiple myeloma |
Q42144052 | Protein kinase CK2 regulates the dimerization of histone deacetylase 1 (HDAC1) and HDAC2 during mitosis |
Q35808644 | Protein-Protein Interactions of Viroporins in Coronaviruses and Paramyxoviruses: New Targets for Antivirals? |
Q45948898 | Pure curcumin increases the expression of SOCS1 and SOCS3 in myeloproliferative neoplasms through suppressing class I histone deacetylases. |
Q41000737 | Regulation of flowering time by the histone deacetylase HDA5 in Arabidopsis |
Q47912834 | Relaxed chromatin induced by histone deacetylase inhibitors improves the oligonucleotide-directed gene editing in plant cells |
Q64054764 | Resveratrol affects hepatic gluconeogenesis via histone deacetylase 4 |
Q36444065 | Retinoblastoma-binding Protein 4-regulated Classical Nuclear Transport Is Involved in Cellular Senescence |
Q49346591 | Role of Dorsal Striatum Histone Deacetylase 5 in Incubation of Methamphetamine Craving. |
Q26768645 | Role of Epigenetics in Stem Cell Proliferation and Differentiation: Implications for Treating Neurodegenerative Diseases |
Q64084615 | Role of Natural Products in Modulating Histone Deacetylases in Cancer |
Q38256576 | Role of SIRT1 in autoimmune demyelination and neurodegeneration |
Q38932108 | Role of epigenetics in modulation of immune response at the junction of host-pathogen interaction and danger molecule signaling |
Q30416582 | Running-induced epigenetic and gene expression changes in the adolescent brain |
Q36115749 | SUMOylation-disrupting WAS mutation converts WASp from a transcriptional activator to a repressor of NF-κB response genes in T cells |
Q38246144 | Selective class IIa HDAC inhibitors: myth or reality |
Q47597906 | Sexually Dimorphic Epigenetic Regulation of Brain-Derived Neurotrophic Factor in Fetal Brain in the Valproic Acid Model of Autism Spectrum Disorder. |
Q64958999 | Stem Cell Ophthalmology Treatment Study: bone marrow derived stem cells in the treatment of Retinitis Pigmentosa. |
Q39264032 | Strong Correlation between the Expression Levels of HDAC4 and SIRT6 in Hematological Malignancies of the Adults |
Q45766607 | Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8. |
Q89752312 | Structural determinants of affinity and selectivity in the binding of inhibitors to histone deacetylase 6 |
Q33566645 | Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-α through up-regulation of TNF receptor 1 in lung cancer cells |
Q40423715 | Suppression of Mammary Carcinogenesis Through Early Exposure to Dietary Lipotropes Occurs Primarily In Utero |
Q92519762 | Synthesis and Preliminary Biological Evaluation of Two Fluoroolefin Analogs of Largazole Inspired by the Structural Similarity of the Side Chain Unit in Psammaplin A |
Q47992034 | Synthesis, characterization, and evaluation of Cd[L-proline]2, a novel histone deacetylase inhibitor that induces epigenetic modification of histone deacetylase isoforms in A549 cells |
Q60049780 | Systematic polypharmacology and drug repurposing via an integrated L1000-based Connectivity Map database mining |
Q47599592 | Targeted Gene Repression Using Novel Bifunctional Molecules to Harness Endogenous Histone Deacetylation Activity. |
Q38051736 | Targeting class I histone deacetylases in cancer therapy |
Q38361065 | Targeting histone deacetylases: a novel approach in Parkinson's disease |
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