Green tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms

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Green tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...752572G
P356DOI10.1371/JOURNAL.PONE.0052572
P932PMC publication ID3527608
P698PubMed publication ID23285096
P5875ResearchGate publication ID234043936

P2093author name stringSanjay Gupta
Natarajan Bhaskaran
Vijay S Thakur
Mark W Jackson
Karishma Gupta
Akbar Nawab
Melissa A Babcook
P2860cites workCleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosisQ24310597
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TP53 mutation in prostate needle biopsies--comparison with patients follow-upQ80562481
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p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E.Q34786224
GREEN TEA POLYPHENOLS MEDIATED APOPTOSIS IN INTESTINAL EPITHELIAL CELLS BY A FADD-DEPENDENT PATHWAYQ35047369
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Selective cell cycle arrest and induction of apoptosis in human prostate cancer cells by a polyphenol-rich extract of Solanum nigrumQ37694690
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Green tea polyphenols increase p53 transcriptional activity and acetylation by suppressing class I histone deacetylasesQ39354874
Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia.Q39446764
Resveratrol enhances the expression of death receptor Fas/CD95 and induces differentiation and apoptosis in anaplastic large-cell lymphoma cells.Q39522537
p53-Dependent p21-mediated growth arrest pre-empts and protects HCT116 cells from PUMA-mediated apoptosis induced by EGCG.Q39707367
Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cellsQ39783504
Plant flavonoid apigenin inactivates Akt to trigger apoptosis in human prostate cancer: an in vitro and in vivo studyQ39947431
Role of Bax in quercetin-induced apoptosis in human prostate cancer cellsQ39985533
Hibiscus polyphenol-rich extract induces apoptosis in human gastric carcinoma cells via p53 phosphorylation and p38 MAPK/FasL cascade pathwayQ40442432
Ablation of either p21 or Bax prevents p53-dependent apoptosis induced by green tea polyphenol epigallocatechin-3-gallate.Q40447313
Downregulation of wild-type p53 protein by HER-2/neu mediated PI3K pathway activation in human breast cancer cells: its effect on cell proliferation and implication for therapy.Q40476195
Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemiasQ40615155
p53 mutations and loss of p53 function confer multidrug resistance in neuroblastomaQ40838799
Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenolsQ41040593
Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylasesQ41128716
Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitorsQ42555454
Theaflavins target Fas/caspase-8 and Akt/pBad pathways to induce apoptosis in p53-mutated human breast cancer cellsQ43227672
Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53.Q43804591
In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathwaysQ44250297
Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cellsQ44534508
Phosphorylation of FADD is critical for sensitivity to anticancer drug-induced apoptosisQ44786861
PTEN/MMAC1/TEP1 involvement in primary prostate cancers.Q47814101
In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug.Q48960489
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectprostate cancerQ181257
polyphenolQ290439
P304page(s)e52572
P577publication date2012-12-20
P1433published inPLOS OneQ564954
P1476titleGreen tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms
P478volume7

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cites work (P2860)
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Q38924245Apigenin induces apoptosis by targeting inhibitor of apoptosis proteins and Ku70-Bax interaction in prostate cancer.
Q64076632Dietary Compounds as Epigenetic Modulating Agents in Cancer
Q38944011Ellagic acid inhibits proliferation and induced apoptosis via the Akt signaling pathway in HCT-15 colon adenocarcinoma cells
Q24568216Epigenetic effects of green tea polyphenols in cancer
Q38674201Fruit Peel Polyphenolic Extract-Induced Apoptosis in Human Breast Cancer Cells Is Associated with ROS Production and Modulation of p38MAPK/Erk1/2 and the Akt Signaling Pathway.
Q51281894Gelsolin-like actin-capping protein is associated with patient prognosis, cellular apoptosis and proliferation in prostate cancer.
Q30381308Liposome-mediated transfection of wild-type P53 DNA into human prostate cancer cells is improved by low-frequency ultrasound combined with microbubbles.
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Q88453818Perspectives on the recent developments with green tea polyphenols in drug discovery
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Q52669353Tea polyphenols induce S phase arrest and apoptosis in gallbladder cancer cells.
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Q34657698Tumour suppressor HLJ1: A potential diagnostic, preventive and therapeutic target in non-small cell lung cancer
Q35284695miR-135b contributes to the radioresistance by targeting GSK3β in human glioblastoma multiforme cells

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