Practical aspects of transporter model systems: a case study involving SQV.

scientific article published in May 2004

Practical aspects of transporter model systems: a case study involving SQV. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1081/DMR-120037570
P698PubMed publication ID15237860

P2093author name stringPatrick J Sinko
Sung-Hack Lee
Yaming Su
P2860cites workDrug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNAQ24564700
MRP3, an organic anion transporter able to transport anti-cancer drugsQ24650550
Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogsQ24681283
Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activationQ28218324
Type I collagen gel modulates extracellular matrix synthesis and deposition by tracheal epithelial cellsQ28583192
P-Glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: the influence of culturing conditions and drug exposure on P-gp expression levels.Q32062298
Localisation of breast cancer resistance protein in microvessel endothelium of human brainQ33962609
Permeability of bovine brain microvessel endothelial cells in vitro: barrier tightening by a factor released from astroglioma cellsQ33969609
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitorsQ34065800
Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma.Q34190633
Antiretroviral treatment of central nervous system HIV-1 infection: a reviewQ34459372
Saquinavir: a review of its use in boosted regimens for treating HIV infectionQ35147073
Tight junction structure and ZO-1 content are identical in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistanceQ36221153
Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cellsQ36472379
Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2).Q39657896
The effect of cell culture conditions on saquinavir transport through, and interactions with, MDCKII cells overexpressing hMDR1.Q40632666
Sulfate conjugating and transport functions of MDCK distal tubular cellsQ40664828
Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugsQ40688656
Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man.Q40690604
Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa?Q40716273
Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa?Q40716277
Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadineQ40753067
Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2)Q40762600
Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug deliveryQ40923441
Extracellular matrix protein-induced changes in human salivary epithelial cell organization and proliferation on a model biological substratumQ40946578
Transferrin receptor polarity and recycling accuracy in "tight" and "leaky" strains of Madin-Darby canine kidney cellsQ41513093
HIV-protease inhibitorsQ41751665
Drug transfer across the blood-brain barrier: correlation between in vitro and in vivo modelsQ42041789
Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domainQ42059686
Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.Q44044782
Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cellsQ44087884
Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A.Q44285527
Inhibition of Organic Anion Transporting Polypeptide-Mediated Hepatic Uptake Is the Major Determinant in the Pharmacokinetic Interaction between Bosentan and Cyclosporin A in the RatQ44655928
In vitro blood-brain barrier permeability of nevirapine compared to other HIV antiretroviral agentsQ48497171
Brain microvessel endothelial cells in tissue culture: a model for study of blood-brain barrier permeabilityQ48729747
Significance of P-glycoprotein for the pharmacology and clinical use of HIV protease inhibitors.Q54059117
Resistance to lipophilic cationic compounds in multidrug resistant leukemia cells.Q54247932
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)377-389
P577publication date2004-05-01
P1433published inDrug Metabolism ReviewsQ5308857
P1476titlePractical aspects of transporter model systems: a case study involving SQV.
P478volume36

Reverse relations

cites work (P2860)
Q37783447Impact of ATP-binding cassette transporters on human immunodeficiency virus therapy
Q45235236Pharmacokinetics and in vivo biodistribution of optimized PLGA nanoparticulate drug delivery system for controlled release of emtricitabine
Q44672643Solid lipid nanoparticles and nanosuspension formulation of Saquinavir: preparation, characterization, pharmacokinetics and biodistribution studies

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