Metformin potentiates rapamycin and cisplatin in gastric cancer in mice

scientific article published in May 2015

Metformin potentiates rapamycin and cisplatin in gastric cancer in mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.3327
P932PMC publication ID4494971
P698PubMed publication ID25909163
P5875ResearchGate publication ID275355577

P2093author name stringYing Chen
Tian Xia
Xiaodong Jiao
Keping Xie
Suyun Huang
Guanzhen Yu
Yunshu Gao
Jiejun Wang
Zhaosheng Li
Wenzheng Fang
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Overexpression of phosphorylated mammalian target of rapamycin predicts lymph node metastasis and prognosis of chinese patients with gastric cancerQ46119167
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Cumulative Metformin Use and Its Impact on Survival in Gastric Cancer Patients After GastrectomyQ53641389
Metformin improves survival and recurrence rate in patients with diabetes and gastric cancerQ60398030
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[A case of advanced gastric cancer with Virchow's node metastasis, responding to concomitant plasma exchange and immunochemotherapy]Q69258325
Surgical approach to early gastric cancer with lymph node metastasisQ69359385
Clinicopathologic studies of gastric cancer with metastasis to the liver--based on the cases detected at initial surgeryQ71304389
Extended indication criteria for endoscopic mucosal resection of early gastric cancer with special reference to lymph node metastasis--examination by multivariate analysisQ80104091
New insight into the key proteins and pathways involved in the metastasis of colorectal carcinomaQ81121636
Tissue microarray analysis reveals strong clinical evidence for a close association between loss of annexin A1 expression and nodal metastasis in gastric cancerQ81413248
The Effect of Locoregional Transarterial Infusion Chemotherapy on Liver Metastasis after Gastric Cancer ResectionQ84828291
Ubiquitin D is an independent prognostic marker for survival in stage IIB-IIC colon cancer patients treated with 5-fluoruracil-based adjuvant chemotherapyQ85342526
Long-term metformin use reduces gastric cancer risk in type 2 diabetics without insulin treatment: a nationwide cohort studyQ87418247
[Metformin induces apoptosis in hepatocellular carcinoma Huh-7 cells in vitro and its mechanism]Q95501236
AMP-activated protein kinase: a target for drugs both ancient and modernQ26864424
Metformin: a therapeutic opportunity in breast cancerQ33733319
Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individualsQ33795313
Long-term metformin use is associated with decreased risk of breast cancer.Q33873130
The influence of transforming growth factor‐α, cyclooxygenase‐2, matrix metalloproteinase (MMP)‐7, MMP‐9 and CXCR4 proteins involved in epithelial–mesenchymal transition on overall survival of patients with gastric cancerQ34274752
Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.Q34786695
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Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancerQ34984314
Braveheart, a long noncoding RNA required for cardiovascular lineage commitmentQ36585810
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Integrin αvβ3 and fibronectin upregulate Slug in cancer cells to promote clot invasion and metastasisQ37334587
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Metformin and cancer: doses, mechanisms and the dandelion and hormetic phenomenaQ37715626
Metformin: its emerging role in oncologyQ37846987
Diabetes mellitus and the risk of cancer.Q37948495
Management of Brain Metastasis: Past Lessons, Modern Management, and Future ConsiderationsQ37954518
Metformin and cancer therapy.Q37962127
Denosumab for the Prevention of Skeletal‐Related Events in Patients with Bone Metastasis from Solid TumorQ37990849
Transcriptional inhibition of p21WAF1/CIP1 gene (CDKN1) expression by survivin is at least partially p53-dependent: Evidence for survivin acting as a transcription factor or co-factorQ39364694
The Antidiabetic Drug Metformin Inhibits Gastric Cancer Cell Proliferation In Vitro and In VivoQ39416862
Metformin plus temozolomide-based chemotherapy as adjuvant treatment for WHO grade III and IV malignant gliomas.Q39727746
AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cellsQ39733339
Decorin suppresses lung metastases of murine osteosarcomaQ39979575
Metformin Suppresses Colorectal Aberrant Crypt Foci in a Short-term Clinical TrialQ42920181
AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer.Q43091920
A case of metastasis from gastric cancer to the thyroid glandQ43696385
Morphology, immunohistochemistry and hTERC gene in-situ hybridization in Barrett's esophagusQ43885898
Tumour suppressor gene expression correlates with gastric cancer prognosisQ44401645
Type 2 diabetes and subsequent incidence of breast cancer in the Nurses' Health StudyQ44453199
P4510describes a project that usesCytoscapeQ3699942
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectmetforminQ19484
sirolimusQ32089
cisplatinQ412415
P304page(s)12748-12762
P577publication date2015-05-01
P1433published inOncotargetQ1573155
P1476titleMetformin potentiates rapamycin and cisplatin in gastric cancer in mice
P478volume6

Reverse relations

cites work (P2860)
Q61810575Avasimibe inhibits tumor growth by targeting FoxM1-AKR1C1 in osteosarcoma
Q92645973CDX1 Expression Induced by CagA-Expressing Helicobacter pylori Promotes Gastric Tumorigenesis
Q42061952Celastrol induces cell cycle arrest by MicroRNA-21-mTOR-mediated inhibition p27 protein degradation in gastric cancer
Q38818730Combinational strategies of metformin and chemotherapy in cancers
Q38715697Effects of Metformin and a Mammalian Target of Rapamycin (mTOR) ATP-Competitive Inhibitor on Targeted Metabolomics in Pancreatic Cancer Cell Line.
Q33829205From rapalogs to anti-aging formula
Q36546520Hippo transducer TAZ promotes epithelial mesenchymal transition and supports pancreatic cancer progression
Q58699189Metformin and blood cancers
Q37688014Metformin and cancer: Quo vadis et cui bono?
Q49658205Metformin enhances the chemosensitivity of hepatocarcinoma cells to cisplatin through AMPK pathway
Q58733981Metformin inhibits ovarian cancer growth and migration in vitro and in vivo by enhancing cisplatin cytotoxicity
Q37708932Metformin potentiates anti-tumor effect of resveratrol on pancreatic cancer by down-regulation of VEGF-B signaling pathway
Q37274957Metformin reduces gastric cancer risk in patients with type 2 diabetes mellitus
Q89158246Metformin sensitizes endometrial cancer cells to chemotherapy through IDH1-induced Nrf2 expression via an epigenetic mechanism
Q97542974Metformin sensitizes therapeutic agents and improves outcome in pre-clinical and clinical diffuse large B-cell lymphoma
Q37644891Metformin use and cervical cancer risk in female patients with type 2 diabetes
Q49183232Metformin use and its effect on gastric cancer in patients with type 2 diabetes: A systematic review of observational studies
Q90575454Metformin use and risk of gastric adenocarcinoma in a Swedish population-based cohort study
Q36292690PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma
Q42365321Redox-dependent modulation of metformin contributes to enhanced sensitivity of esophageal squamous cell carcinoma to cisplatin
Q38819571Role of AMPK signaling in mediating the anticancer effects of silibinin in esophageal squamous cell carcinoma
Q38826019SPARCL1 is a novel predictor of tumor recurrence and survival in hilar cholangiocarcinoma
Q38375735Study protocol of a phase IB/II clinical trial of metformin and chloroquine in patients with IDH1-mutated or IDH2-mutated solid tumours
Q38728567The expanding role of metformin in cancer: an update on antitumor mechanisms and clinical development
Q38744613The predictive potential and oncogenic effects of HOXC8 expression on osteosarcoma

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