review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1111/J.0105-2896.2004.00170.X |
P8608 | Fatcat ID | release_xg7y3bconnckjg2kzntgrwssgi |
P698 | PubMed publication ID | 15242393 |
P2093 | author name string | Ferenc Livák | |
P2860 | cites work | Why PLoS became a publisher | Q21146442 |
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination | Q24294409 | ||
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses | Q24677973 | ||
Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX | Q28139663 | ||
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage | Q28144576 | ||
The RAG proteins and V(D)J recombination: complexes, ends, and transposition | Q28145648 | ||
ATM phosphorylates histone H2AX in response to DNA double-strand breaks | Q28188651 | ||
Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX | Q28191330 | ||
Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination | Q28275539 | ||
RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination | Q28307236 | ||
Genomic instability in mice lacking histone H2AX | Q28589826 | ||
RAG-1-deficient mice have no mature B and T lymphocytes | Q28592133 | ||
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement | Q28594711 | ||
Evolution of the recombination signal sequences in the Ig heavy-chain variable region locus of mammals | Q28776622 | ||
Somatic generation of antibody diversity | Q29616439 | ||
High mobility of proteins in the mammalian cell nucleus | Q29616460 | ||
Atm-deficient mice: a paradigm of ataxia telangiectasia | Q29619532 | ||
DNA hairpin opening mediated by the RAG1 and RAG2 proteins | Q33652023 | ||
Structural basis of T cell recognition | Q33652495 | ||
Chromosomal breakage syndromes | Q33711443 | ||
Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences | Q33775546 | ||
RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex | Q33958065 | ||
Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking | Q33958242 | ||
Mechanistic basis for coding end sequence effects in the initiation of V(D)J recombination | Q33960582 | ||
Postcleavage sequence specificity in V(D)J recombination | Q33964568 | ||
The DDE motif in RAG-1 is contributed in trans to a single active site that catalyzes the nicking and transesterification steps of V(D)J recombination | Q33966875 | ||
RAG transposase can capture and commit to target DNA before or after donor cleavage | Q33968578 | ||
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX | Q34031720 | ||
Ordered assembly of the V(D)J synaptic complex ensures accurate recombination | Q34090070 | ||
Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity | Q34098891 | ||
Spatial and temporal cellular responses to single-strand breaks in human cells. | Q34197035 | ||
Assembly of the RAG1/RAG2 synaptic complex | Q34290414 | ||
The MHC reactivity of the T cell repertoire prior to positive and negative selection. | Q34418401 | ||
The mechanism and regulation of chromosomal V(D)J recombination | Q34619795 | ||
V(D)J recombination: RAG proteins, repair factors, and regulation | Q34667417 | ||
Interfaces between the detection, signaling, and repair of DNA damage | Q34762844 | ||
Sensing of intermediates in V(D)J recombination by ATM. | Q35005088 | ||
Mechanisms that direct ordered assembly of T cell receptor beta locus V, D, and J gene segments | Q35173467 | ||
Recombinase-activating gene (RAG) 2-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice | Q35795447 | ||
In vitro V(D)J recombination: signal joint formation | Q35940601 | ||
Transient restoration of gene rearrangement at multiple T cell receptor loci in gamma-irradiated scid mice | Q36367068 | ||
Immature thymocytes undergoing receptor rearrangements are resistant to an Atm-dependent death pathway activated in mature T cells by double-stranded DNA breaks | Q36368896 | ||
Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling | Q36370482 | ||
Genetic modulation of T cell receptor gene segment usage during somatic recombination | Q36376045 | ||
How many thymocytes audition for selection? | Q36380676 | ||
Sequence of the spacer in the recombination signal sequence affects V(D)J rearrangement frequency and correlates with nonrandom Vkappa usage in vivo | Q36400779 | ||
H2AX haploinsufficiency modifies genomic stability and tumor susceptibility | Q36533572 | ||
rag-1 and rag-2 are components of a high-molecular-weight complex, and association of rag-2 with this complex is rag-1 dependent | Q36555390 | ||
T-cell receptor alpha locus V(D)J recombination by-products are abundant in thymocytes and mature T cells | Q36557127 | ||
Cryptic signals and the fidelity of V(D)J joining | Q36568596 | ||
Basic helix-loop-helix proteins E2A and HEB induce immature T-cell receptor rearrangements in nonlymphoid cells. | Q38296131 | ||
The nicking step in V(D)J recombination is independent of synapsis: implications for the immune repertoire | Q38307676 | ||
Hairpin coding end opening is mediated by RAG1 and RAG2 proteins | Q38329558 | ||
V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2. | Q38334568 | ||
Structure of nonhairpin coding-end DNA breaks in cells undergoing V(D)J recombination | Q39631050 | ||
Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair | Q39674379 | ||
The role of components of recombination signal sequences in immunoglobulin gene segment usage: a V81x model. | Q39729937 | ||
DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner | Q40315391 | ||
New insights into V(D)J recombination and its role in the evolution of the immune system | Q40429013 | ||
The B12/23 restriction is critically dependent on recombination signal nonamer and spacer sequences | Q40609333 | ||
DNA-Rag Protein Interactions in the Control of Selective D Gene Utilization in the TCRβ Locus | Q40633187 | ||
The kinetics of V-J joining throughout 3.5 megabases of the mouse Ig kappa locus fit a constrained diffusion model of nuclear organization | Q40670837 | ||
Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule. | Q40874673 | ||
Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system | Q41011364 | ||
Identification of V(D)J recombination coding end intermediates in normal thymocytes | Q41120267 | ||
RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination | Q41157754 | ||
Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro | Q41191663 | ||
Initiation of V(D)J recombination in vitro obeying the 12/23 rule | Q41218012 | ||
Essential and perilous: V(D)J recombination and DNA damage checkpoints in lymphocyte precursors | Q41512971 | ||
Extent to which homology can constrain coding exon junctional diversity in V(D)J recombination | Q41547272 | ||
The cleavage efficiency of the human immunoglobulin heavy chain VH elements by the RAG complex: implications for the immune repertoire | Q43470902 | ||
T-cell receptor delta gene rearrangements in early thymocytes | Q46048219 | ||
Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement | Q46862481 | ||
V(D)J Recombination Frequencies Can Be Profoundly Affected by Changes in the Spacer Sequence | Q47395217 | ||
Recombination signal sequence variations and the mechanism of patterned T-cell receptor-beta locus rearrangement | Q47714121 | ||
DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations | Q47750695 | ||
Evolutionarily conserved pattern of gene segment usage within the mammalian TCRbeta locus | Q47779893 | ||
The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination | Q48313594 | ||
Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps | Q49167454 | ||
Rejoining of DNA by the RAG1 and RAG2 proteins | Q49172612 | ||
Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells. | Q51840167 | ||
Cutting edge: targeting of V beta to D beta rearrangement by RSSs can be mediated by the V(D)J recombinase in the absence of additional lymphoid-specific factors. | Q51840746 | ||
Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining. | Q52244112 | ||
Chromosomal translocations in human cancer. | Q52512616 | ||
Biased V beta usage in immature thymocytes is independent of DJ beta proximity and pT alpha pairing. | Q52927147 | ||
Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence. | Q54159375 | ||
Rapid identification of local T cell expansion in inflammatory organ diseases by flow cytometric T cell receptor Vβ analysis | Q58880326 | ||
P304 | page(s) | 23-35 | |
P577 | publication date | 2004-08-01 | |
P1433 | published in | Immunological Reviews | Q15724582 |
P1476 | title | In vitro and in vivo studies on the generation of the primary T-cell receptor repertoire | |
P478 | volume | 200 |
Q34722732 | ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks | cites work | P2860 |
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