DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner

scientific article published on December 2003

DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/GKG921
P932PMC publication ID290281
P698PubMed publication ID14627815
P5875ResearchGate publication ID277503628

P2093author name stringJi-Hye Park
Eun-Jung Park
Marjorie A Oettinger
Jongbum Kwon
Doug W Chan
P2860cites workTranslating the Histone CodeQ22065840
Crystal structure of the nucleosome core particle at 2.8 A resolutionQ22122355
Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosisQ24290159
Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complexQ24522344
Synapsis of DNA ends by DNA-dependent protein kinaseQ24536754
Megabase chromatin domains involved in DNA double-strand breaks in vivoQ24680284
Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repairQ27634006
The language of covalent histone modificationsQ27860931
Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku proteinQ27876219
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaksQ27919629
A role for Saccharomyces cerevisiae histone H2A in DNA repair.Q27930827
Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.Q27935926
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139Q28131715
Histone acetylation in chromatin structure and transcriptionQ28131749
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damageQ28144576
ATP-dependent remodeling and acetylation as regulators of chromatin fluidityQ28145156
Histone H2A variants H2AX and H2AZQ28207014
The DNA-dependent protein kinaseQ28373950
Genomic instability in mice lacking histone H2AXQ28589826
Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acidsQ28608946
Histone acetylation and transcriptional regulatory mechanismsQ29547707
Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosomeQ29618064
Alteration of nucleosome structure as a mechanism of transcriptional regulationQ29620047
Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinaseQ30845708
Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studiesQ33887333
Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoiningQ33958394
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AXQ34031720
Epigenetic consequences of nucleosome dynamicsQ34157982
Histone H3 and the histone acetyltransferase Hat1p contribute to DNA double-strand break repairQ34286591
Sensing and repairing DNA double-strand breaksQ34642563
Histone acetyl transferases: a role in DNA repair and DNA replicationQ34788415
Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase IIQ37344366
Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1.Q38329553
Chromatin disruption and modificationQ39726920
Structure, dynamics, and function of chromatin in vitroQ47910966
The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunitQ64389407
Overcoming a nucleosomal barrier to transcriptionQ71729702
Purification and characterization of the double-stranded DNA-activated protein kinase, DNA-PK, from human placentaQ73078574
Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNAQ73270505
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)6819-6827
P577publication date2003-12-01
P1433published inNucleic Acids ResearchQ135122
P1476titleDNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner
P478volume31

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cites work (P2860)
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