| scholarly article | Q13442814 |
| P2093 | author name string | Jun Qin | |
| David J Chen | |||
| Michael D Story | |||
| Doug W Chan | |||
| Akihiro Kurimasa | |||
| Benjamin Ping-Chi Chen | |||
| Sheela Prithivirajsingh | |||
| P2860 | cites work | SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint | Q24292395 |
| Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 | Q24311891 | ||
| Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage | Q24672492 | ||
| Megabase chromatin domains involved in DNA double-strand breaks in vivo | Q24680284 | ||
| Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells | Q27860926 | ||
| The DNA damage response: putting checkpoints in perspective | Q28131713 | ||
| A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage | Q28144576 | ||
| ATM phosphorylates histone H2AX in response to DNA double-strand breaks | Q28188651 | ||
| Chromosomal stability and the DNA double-stranded break connection | Q28205315 | ||
| The DNA-dependent protein kinase | Q28373950 | ||
| The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen | Q28608938 | ||
| Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids | Q28608946 | ||
| Enhanced phosphorylation of p53 by ATM in response to DNA damage | Q28609838 | ||
| Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies | Q33887333 | ||
| Partners and pathwaysrepairing a double-strand break. | Q33927291 | ||
| Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining | Q33958394 | ||
| DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme? | Q34180691 | ||
| Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin | Q34663629 | ||
| DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair | Q34868235 | ||
| DNA-dependent protein kinase: DNA binding and activation in the absence of Ku | Q35739034 | ||
| DNA looping by Ku and the DNA-dependent protein kinase | Q36126604 | ||
| Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen | Q36774702 | ||
| Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II | Q37344366 | ||
| Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase | Q38298404 | ||
| DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus | Q40892156 | ||
| Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line | Q41368190 | ||
| Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways | Q41861185 | ||
| Pulsed-field gel electrophoretic analysis of DNA double-strand breaks in mammalian cells using photostimulable storage phosphor imaging | Q45038546 | ||
| Identification of phosphorylation sites in proteins separated by polyacrylamide gel electrophoresis | Q48022079 | ||
| DNA end-joining: from yeast to man | Q63362924 | ||
| Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks | Q64388968 | ||
| The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit | Q64389407 | ||
| Purification and characterization of the double-stranded DNA-activated protein kinase, DNA-PK, from human placenta | Q73078574 | ||
| P433 | issue | 18 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2333-8 | |
| P577 | publication date | 2002-09-15 | |
| P1433 | published in | Genes & Development | Q1524533 |
| P1476 | title | Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks | |
| P478 | volume | 16 |
| Q93055030 | "An End to a Means": How DNA-End Structure Shapes the Double-Strand Break Repair Process |
| Q52572400 | 53BP1 contributes to survival of cells irradiated with X-ray during G1 without Ku70 or Artemis. |
| Q40405429 | A cell-permeable, activity-based probe for protein and lipid kinases |
| Q37297350 | A hormone-DNA repair circuit governs the response to genotoxic insult |
| Q36777827 | A mechanism for DNA-PK activation requiring unique contributions from each strand of a DNA terminus and implications for microhomology-mediated nonhomologous DNA end joining |
| Q33656610 | A method for systematic mapping of protein lysine methylation identifies functions for HP1β in DNA damage response |
| Q33553010 | A novel and simple micro-irradiation technique for creating localized DNA double-strand breaks |
| Q35842448 | A sensitive and quantitative polymerase chain reaction-based cell free in vitro non-homologous end joining assay for hematopoietic stem cells |
| Q34610477 | A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation |
| Q29547735 | ATM and related protein kinases: safeguarding genome integrity |
| Q36420668 | ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage |
| Q33967609 | ATR autophosphorylation as a molecular switch for checkpoint activation. |
| Q39129038 | ATR-dependent phosphorylation of DNA-dependent protein kinase catalytic subunit in response to UV-induced replication stress |
| Q30838969 | Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity. |
| Q34353620 | Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes |
| Q60913420 | Activation of EGFR-DNA-PKcs pathway by IGFBP2 protects esophageal adenocarcinoma cells from acidic bile salts-induced DNA damage |
| Q35666040 | Adeno-associated virus type 2 modulates the host DNA damage response induced by herpes simplex virus 1 during coinfection. |
| Q40270537 | Aggregative organization enhances the DNA end-joining process that is mediated by DNA-dependent protein kinase |
| Q33948911 | Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometry |
| Q35423647 | Analysis of mutations that dissociate G(2) and essential S phase functions of human ataxia telangiectasia-mutated and Rad3-related (ATR) protein kinase |
| Q24561444 | Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response |
| Q39184770 | Artemis-dependent DNA double-strand break formation at stalled replication forks |
| Q53581072 | Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break. |
| Q41611998 | Aurora A kinase regulates non-homologous end-joining and poly(ADP-ribose) polymerase function in ovarian carcinoma cells |
| Q33282240 | Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks |
| Q40701520 | Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice |
| Q27919641 | Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair |
| Q39946274 | Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends |
| Q24632998 | BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair |
| Q34313012 | BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle |
| Q26827232 | Beyond DNA repair: DNA-PK function in cancer |
| Q40575476 | Binding of the DNA-dependent protein kinase catalytic subunit to Holliday junctions |
| Q39003035 | Biological effects of (125)i seeds radiation on A549 lung cancer cells: G2/M arrest and enhanced cell death |
| Q64374900 | Biphasic Functional Interaction between the Adenovirus E4orf4 Protein and DNA-PK |
| Q41921396 | Bortezomib induces protective autophagy through AMP-activated protein kinase activation in cultured pancreatic and colorectal cancer cells |
| Q36627909 | Candidate protein biodosimeters of human exposure to ionizing radiation. |
| Q40464510 | Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks. |
| Q53572324 | Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair. |
| Q26771165 | Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization |
| Q37648742 | Cellular radiosensitivity: how much better do we understand it? |
| Q34017668 | Cetuximab augments cytotoxicity with poly (adp-ribose) polymerase inhibition in head and neck cancer |
| Q35029335 | Choosing the right path: does DNA-PK help make the decision? |
| Q38820654 | Combining carbon ion irradiation and non-homologous end-joining repair inhibitor NU7026 efficiently kills cancer cells |
| Q24653672 | Common mechanisms of PIKK regulation |
| Q34825234 | Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair |
| Q29614218 | Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage |
| Q37656781 | Coordination of the Ser2056 and Thr2609 Clusters of DNA-PKcs in Regulating Gamma Rays and Extremely Low Fluencies of Alpha-Particle Irradiation to G0/G1 Phase Cells |
| Q33811685 | Creating localized DNA double-strand breaks with microirradiation |
| Q36571177 | Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding |
| Q36345337 | Crypt base columnar stem cells in small intestines of mice are radioresistant |
| Q33912831 | Cyclin-C-dependent cell-cycle entry is required for activation of non-homologous end joining DNA repair in postmitotic neurons |
| Q36073749 | DNA Damage Response Assessments in Human Tumor Samples Provide Functional Biomarkers of Radiosensitivity |
| Q36055517 | DNA damage intensity in fibroblasts in a 3-dimensional collagen matrix correlates with the Bragg curve energy distribution of a high LET particle |
| Q37135926 | DNA double strand break repair via non-homologous end-joining |
| Q37143132 | DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases |
| Q37855947 | DNA double-strand break repair, immunodeficiency and the RIDDLE syndrome |
| Q44692118 | DNA end sequestration by DNA-dependent protein kinase and end joining of sterically constrained substrates in whole-cell extracts |
| Q37146966 | DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells |
| Q42033895 | DNA-PK Inhibition by NU7441 Enhances Chemosensitivity to Topoisomerase Inhibitor in Non-Small Cell Lung Carcinoma Cells by Blocking DNA Damage Repair |
| Q27919702 | DNA-PK autophosphorylation facilitates Artemis endonuclease activity |
| Q40315391 | DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner |
| Q35759209 | DNA-PK is involved in repairing a transient surge of DNA breaks induced by deceleration of DNA replication |
| Q44643710 | DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination |
| Q40184751 | DNA-PK phosphorylation sites on Oct-1 promote cell survival following DNA damage |
| Q36588889 | DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. |
| Q26866928 | DNA-PK: a dynamic enzyme in a versatile DSB repair pathway |
| Q28305446 | DNA-PK: the means to justify the ends? |
| Q37614607 | DNA-PKcs activates the Chk2-Brca1 pathway during mitosis to ensure chromosomal stability |
| Q42007528 | DNA-PKcs and ATM co-regulate DNA double-strand break repair |
| Q50287403 | DNA-PKcs autophosphorylates |
| Q36017508 | DNA-PKcs function regulated specifically by protein phosphatase 5 |
| Q38852980 | DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis |
| Q40497393 | DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks. |
| Q36119555 | DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys? |
| Q92980463 | DNA-dependent protein kinase in telomere maintenance and protection |
| Q92622433 | DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP |
| Q41954597 | DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM). |
| Q58591000 | Deciphering phenotypic variance in different models of DNA-PKcs deficiency |
| Q37528773 | Defective chromatin recruitment and retention of NHEJ core components in human tumor cells expressing a Cyclin E fragment |
| Q36563006 | Detection of γH2AX foci in mouse normal brain and brain tumor after boron neutron capture therapy |
| Q37692283 | Differential radiosensitivity phenotypes of DNA-PKcs mutations affecting NHEJ and HRR systems following irradiation with gamma-rays or very low fluences of alpha particles |
| Q34775122 | Differential role of DNA-PKcs phosphorylations and kinase activity in radiosensitivity and chromosomal instability |
| Q26997852 | Diseases associated with defective responses to DNA damage |
| Q44548807 | Distinct pathways of nonhomologous end joining that are differentially regulated by DNA-dependent protein kinase-mediated phosphorylation |
| Q24675041 | Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4 |
| Q33602897 | Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks |
| Q28283273 | ERCC1-XPF endonuclease facilitates DNA double-strand break repair |
| Q35944680 | Early events in the DNA damage response |
| Q35167659 | Effects of targeted phosphorylation site mutations in the DNA-PKcs phosphorylation domain on low and high LET radiation sensitivity |
| Q35120808 | Evidence for a remodelling of DNA-PK upon autophosphorylation from electron microscopy studies |
| Q36909296 | Evidence for an inositol hexakisphosphate-dependent role for Ku in mammalian nonhomologous end joining that is independent of its role in the DNA-dependent protein kinase |
| Q43462393 | Experimental design, validation and computational modeling uncover DNA damage sensing by DNA-PK and ATM. |
| Q33304039 | Extensive ssDNA end formation at DNA double-strand breaks in non-homologous end-joining deficient cells during the S phase |
| Q47234216 | GSK3β negatively regulates TRAX, a scaffold protein implicated in mental disorders, for NHEJ-mediated DNA repair in neurons. |
| Q37196316 | Genetic variations in DNA repair genes, radiosensitivity to cancer and susceptibility to acute tissue reactions in radiotherapy-treated cancer patients |
| Q34123644 | Genome resequencing and bioinformatic analysis of SNP containing candidate genes in the autoimmune vitiligo Smyth line chicken model |
| Q90862796 | Genome-wide identification of DNA-PKcs-associated RNAs by RIP-Seq |
| Q28258404 | Genomic instability in laminopathy-based premature aging |
| Q39466880 | Genotoxicity of acute and chronic gamma-irradiation on zebrafish cells and consequences for embryo development. |
| Q39772659 | Glycogen synthase kinase 3beta inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons |
| Q37021560 | HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase |
| Q39705486 | Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability |
| Q21091196 | Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response |
| Q36544158 | ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation |
| Q27919628 | Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase |
| Q27919645 | Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. |
| Q40255306 | Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation |
| Q34365204 | Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination |
| Q34667525 | Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell. |
| Q38784311 | Investigation of the DNA damage response to SFOM-0046, a new small-molecule drug inducing DNA double-strand breaks |
| Q34752724 | Involvement of DNA-dependent protein kinase in normal cell cycle progression through mitosis |
| Q34972885 | Involvement of novel autophosphorylation sites in ATM activation |
| Q49337420 | Knockdown of Annexin A1 Enhances Radioresistance and Inhibits Apoptosis in Nasopharyngeal Carcinoma |
| Q38762742 | Knockdown of NFBD1/MDC1 enhances chemosensitivity to cisplatin or 5-fluorouracil in nasopharyngeal carcinoma CNE1 cells |
| Q33569765 | Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex. |
| Q36249787 | LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair |
| Q33992575 | Lens fiber cell differentiation and denucleation are disrupted through expression of the N-terminal nuclear receptor box of NCOA6 and result in p53-dependent and p53-independent apoptosis |
| Q37778044 | Ligase IV Syndrome |
| Q40577621 | Linkage between Werner syndrome protein and the Mre11 complex via Nbs1. |
| Q37170760 | Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice |
| Q42155036 | Lysines 3241 and 3260 of DNA-PKcs are important for genomic stability and radioresistance |
| Q28282983 | MDC1 regulates DNA-PK autophosphorylation in response to DNA damage |
| Q38310324 | Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction |
| Q35542018 | Mechanism and regulation of human non-homologous DNA end-joining |
| Q34317108 | Mechanisms of double-strand break repair in somatic mammalian cells |
| Q34805983 | Mechanistic Insight into DNA Damage and Repair in Ischemic Stroke: Exploiting the Base Excision Repair Pathway as a Model of Neuroprotection |
| Q35543795 | Mending the Break: Two DNA Double-Strand Break Repair Machines in Eukaryotes |
| Q64387978 | Modeling the interplay between DNA-PK, Artemis, and ATM in non-homologous end-joining repair in G1 phase of the cell cycle |
| Q39982082 | Modification of the ionizing radiation response in living cells by an scFv against the DNA-dependent protein kinase |
| Q37473890 | Modifying the function of DNA repair nanomachines for therapeutic benefit |
| Q36204487 | Molecular basis of ataxia telangiectasia and related diseases |
| Q90065722 | Monophosphoryl lipid A alleviated radiation-induced testicular injury through TLR4-dependent exosomes |
| Q34161464 | More forks on the road to replication stress recovery |
| Q35551885 | NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor |
| Q44982147 | Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends. |
| Q38842751 | Non-homologous end joining: advances and frontiers. |
| Q33854272 | Non-homologous end joining: emerging themes and unanswered questions |
| Q28260337 | Non-homologous end-joining, a sticky affair |
| Q36349861 | Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks. |
| Q34602683 | Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells. |
| Q92752056 | Ouabain-regulated phosphoproteome reveals molecular mechanisms for Na+, K+-ATPase control of cell adhesion, proliferation, and survival |
| Q39651756 | Over-expression of miR-100 is responsible for the low-expression of ATM in the human glioma cell line: M059J |
| Q33341346 | PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle |
| Q47224804 | PIDD mediates the association of DNA-PKcs and ATR at stalled replication forks to facilitate the ATR signaling pathway |
| Q30421888 | PP6 regulatory subunit R1 is bidentate anchor for targeting protein phosphatase-6 to DNA-dependent protein kinase |
| Q64386916 | Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch Recombination |
| Q35891614 | Phosphorylation in the serine/threonine 2609-2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts |
| Q33836127 | Phosphorylation of linker histones by DNA-dependent protein kinase is required for DNA ligase IV-dependent ligation in the presence of histone H1. |
| Q21296796 | Phosphorylation: the molecular switch of double-strand break repair |
| Q37369379 | Possible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processing |
| Q34190250 | Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage |
| Q33705076 | Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX. |
| Q35050820 | Protein phosphatase PP6 is required for homology-directed repair of DNA double-strand breaks |
| Q36589890 | Quantitative profiling of DNA damage and apoptotic pathways in UV damaged cells using PTMScan Direct |
| Q57462887 | RPA1 downregulation enhances nasopharyngeal cancer radiosensitivity via blocking RAD51 to the DNA damage site |
| Q39053415 | RSK2 and its binding partners in cell proliferation, transformation and cancer development. |
| Q42139576 | Rad50 ATPase activity is regulated by DNA ends and requires coordination of both active sites. |
| Q40393152 | Radiation sensitivities of 31 human oesophageal squamous cell carcinoma cell lines |
| Q92525683 | Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase |
| Q37024025 | Radiation-induced EGFR-signaling and control of DNA-damage repair |
| Q39706795 | Radiation-induced XRCC4 association with chromatin DNA analyzed by biochemical fractionation. |
| Q40401323 | Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase |
| Q36939257 | Rapid Diminution in the Level and Activity of DNA-Dependent Protein Kinase in Cancer Cells by a Reactive Nitro-Benzoxadiazole Compound |
| Q28262730 | Regulation of DNA double-strand break repair pathway choice |
| Q24296152 | Regulation of DNA-dependent protein kinase by protein kinase CK2 in human glioblastoma cells |
| Q51175908 | Regulation of human polλ by ATM-mediated phosphorylation during non-homologous end joining. |
| Q33886979 | Regulation of the DNA Damage Response to DSBs by Post-Translational Modifications |
| Q37137813 | Regulation of the DNA damage response on male meiotic sex chromosomes |
| Q36500044 | Relative biological effects of neutron mixed-beam irradiation for boron neutron capture therapy on cell survival and DNA double-strand breaks in cultured mammalian cells |
| Q37365625 | Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining |
| Q36729343 | Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway |
| Q43101429 | Response to DNA damage: why do we need to focus on protein phosphatases? |
| Q38047648 | Reversion of the ErbB malignant phenotype and the DNA damage response. |
| Q35991577 | Revival of the abandoned therapeutic wortmannin by nanoparticle drug delivery. |
| Q41716207 | Rho GTPase independent regulation of ATM activation and cell survival by the RhoGEF Net1A. |
| Q28274124 | Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment |
| Q28266265 | Role of non-homologous end joining in V(D)J recombination |
| Q64115640 | SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair |
| Q35020201 | Scanning fluorescence correlation spectroscopy techniques to quantify the kinetics of DNA double strand break repair proteins after γ-irradiation and bleomycin treatment |
| Q37520990 | Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine |
| Q36022277 | Silencing NFBD1/MDC1 enhances the radiosensitivity of human nasopharyngeal cancer CNE1 cells and results in tumor growth inhibition. |
| Q36609468 | Single extreme low dose/low dose rate irradiation causes alteration in lifespan and genome instability in primary human cells |
| Q35668100 | Smarcal1 promotes double-strand-break repair by nonhomologous end-joining. |
| Q42044832 | Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links |
| Q37634166 | Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization |
| Q36948528 | Spontaneous tumor development in bone marrow-rescued DNA-PKcs(3A/3A) mice due to dysfunction of telomere leading strand deprotection |
| Q92091990 | Structural basis of allosteric regulation of Tel1/ATM kinase |
| Q24338991 | Suppression of nonhomologous end joining repair by overexpression of HMGA2 |
| Q28287476 | Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation |
| Q36676871 | Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence |
| Q50054937 | Temporal DNA-PK activation drives genomic instability and therapy resistance in glioma stem cells |
| Q25257508 | Terminal DNA structure and ATP influence binding parameters of the DNA-dependent protein kinase at an early step prior to DNA synapsis |
| Q35195010 | The ATR signaling pathway is disabled during infection with the parvovirus minute virus of mice |
| Q35555479 | The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry |
| Q37366735 | The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation |
| Q40198361 | The DNA-dependent protein kinase catalytic subunit is phosphorylated in vivo on threonine 3950, a highly conserved amino acid in the protein kinase domain |
| Q35830413 | The DNA-dependent protein kinase: the director at the end. |
| Q30387488 | The Dimeric Architecture of Checkpoint Kinases Mec1ATR and Tel1ATM Reveal a Common Structural Organization |
| Q54209627 | The HTLV-1 basic leucine zipper factor (HBZ) attenuates repair of double-stranded DNA breaks via non-homologous end joining (NHEJ). |
| Q37099973 | The Ku80 carboxy terminus stimulates joining and artemis-mediated processing of DNA ends |
| Q33835957 | The Ku‐dependent non‐homologous end‐joining pathway contributes to low‐dose radiation‐stimulated cell survival |
| Q36666163 | The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation |
| Q90170174 | The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage |
| Q40499588 | The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner |
| Q37843633 | The cellular response to DNA damage: a focus on MDC1 and its interacting proteins |
| Q37527220 | The cyclin A1-CDK2 complex regulates DNA double-strand break repair. |
| Q28744087 | The effect of DNA-dependent protein kinase on adeno-associated virus replication |
| Q37048174 | The endless tale of non-homologous end-joining |
| Q24810597 | The leucine rich region of DNA-PKcs contributes to its innate DNA affinity. |
| Q35980970 | The life and death of DNA-PK. |
| Q35136164 | The mammalian XRCC genes: their roles in DNA repair and genetic stability |
| Q39515166 | The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy |
| Q51721326 | The profiles of gamma-H2AX along with ATM/DNA-PKcs activation in the lymphocytes and granulocytes of rat and human blood exposed to gamma rays. |
| Q40323910 | The role of DNA dependent protein kinase in synapsis of DNA ends. |
| Q35830410 | The role of the non-homologous end-joining pathway in lymphocyte development |
| Q26777016 | Therapeutic Implications for Overcoming Radiation Resistance in Cancer Therapy |
| Q35309264 | Thr-1989 phosphorylation is a marker of active ataxia telangiectasia-mutated and Rad3-related (ATR) kinase |
| Q39290667 | Threonine 2609 phosphorylation of the DNA-dependent protein kinase is a critical prerequisite for epidermal growth factor receptor-mediated radiation resistance |
| Q35743835 | Thrombopoietin promotes NHEJ DNA repair in hematopoietic stem cells through specific activation of Erk and NF-κB pathways and their target, IEX-1 |
| Q28475376 | Topoisomerase II-Mediated DNA Damage Is Differently Repaired during the Cell Cycle by Non-Homologous End Joining and Homologous Recombination |
| Q41130676 | Topoisomerase IIalpha-dependent induction of a persistent DNA damage response in response to transient etoposide exposure. |
| Q40603571 | Unraveling the complexities of DNA-dependent protein kinase autophosphorylation |
| Q24336079 | Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage |
| Q34025834 | WRN participates in translesion synthesis pathway through interaction with NBS1 |
| Q33292399 | Werner syndrome protein associates with gamma H2AX in a manner that depends upon Nbs1. |
| Q41319392 | What Combined Measurements From Structures and Imaging Tell Us About DNA Damage Responses. |
| Q27933248 | Yeast Nej1 is a key participant in the initial end binding and final ligation steps of nonhomologous end joining |
| Q42321289 | mTORC1 and -2 Coordinate Transcriptional and Translational Reprogramming in Resistance to DNA Damage and Replicative Stress in Breast Cancer Cells. |
| Q38720892 | miR-21-mediated Radioresistance Occurs via Promoting Repair of DNA Double Strand Breaks |
| Q40160195 | trans Autophosphorylation at DNA-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining |
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