scholarly article | Q13442814 |
P819 | ADS bibcode | 1992PNAS...8911920D |
P356 | DOI | 10.1073/PNAS.89.24.11920 |
P953 | full work available at URL | https://europepmc.org/articles/PMC50669 |
https://europepmc.org/articles/PMC50669?pdf=render | ||
P932 | PMC publication ID | 50669 |
P698 | PubMed publication ID | 1465419 |
P5875 | ResearchGate publication ID | 21691138 |
P50 | author | William Dynan | Q88524515 |
P2093 | author name string | H. Lu | |
A. Dvir | |||
S. R. Peterson | |||
M. W. Knuth | |||
P2860 | cites work | Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndrome | Q24558767 |
A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II | Q24614481 | ||
A DNA-activated protein kinase from HeLa cell nuclei | Q24633308 | ||
Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II | Q27932567 | ||
CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae | Q27934743 | ||
A cDNA encoding RAP74, a general initiation factor for transcription by RNA polymerase II | Q28119106 | ||
Purification and characterization of proximal sequence element-binding protein 1, a transcription activating protein related to Ku and TREF that binds the proximal sequence element of the human U1 promoter | Q28253961 | ||
cDNA-derived amino acid sequence of the 86-kDa subunit of the Ku antigen | Q28278340 | ||
Cloning of a human gene encoding the general transcription initiation factor IIB | Q28292676 | ||
The human U1 snRNA promoter correctly initiates transcription in vitro and is activated by PSE1 | Q28621556 | ||
Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases | Q29617053 | ||
The C-terminal repeat domain of RNA polymerase II largest subunit is essential in vivo but is not required for accurate transcription initiation in vitro | Q33576282 | ||
Mutations in RNA polymerase II enhance or suppress mutations in GAL4. | Q33850755 | ||
Double-stranded DNA induces the phosphorylation of several proteins including the 90 000 mol. wt. heat-shock protein in animal cell extracts | Q33930822 | ||
An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters | Q34306436 | ||
Molecular cloning of cDNA encoding the p70 (Ku) lupus autoantigen | Q35131599 | ||
The C-terminal domain of the largest subunit of RNA polymerase II of Saccharomyces cerevisiae, Drosophila melanogaster, and mammals: a conserved structure with an essential function | Q35619254 | ||
Analysis of the mechanism of interaction of simian Ku protein with DNA | Q35788212 | ||
Use of monoclonal antibodies for the characterization of novel DNA-binding proteins recognized by human autoimmune sera | Q36349787 | ||
Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex | Q36774375 | ||
Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen | Q36774702 | ||
Genetic analysis of the repetitive carboxyl-terminal domain of the largest subunit of mouse RNA polymerase II | Q36780765 | ||
A carboxyl-terminal-domain kinase associated with RNA polymerase II transcription factor delta from rat liver | Q37151396 | ||
A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II. | Q37537860 | ||
Mechanism of promoter selection by RNA polymerase II: mammalian transcription factors alpha and beta gamma promote entry of polymerase into the preinitiation complex | Q37548660 | ||
The small subunit of transcription factor IIF recruits RNA polymerase II into the preinitiation complex | Q37617495 | ||
Nuclear proteins TREF1 and TREF2 bind to the transcriptional control element of the transferrin receptor gene and appear to be associated as a heterodimer | Q38343243 | ||
Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap | Q40684049 | ||
Transcription-dependent structural changes in the C-terminal domain of mammalian RNA polymerase subunit IIa/o. | Q41305990 | ||
Identification of phosphorylation sites in the repetitive carboxyl-terminal domain of the mouse RNA polymerase II largest subunit. | Q41695825 | ||
CTD kinase associated with yeast RNA polymerase II initiation factor b. | Q44229085 | ||
Inhibition of in vivo and in vitro transcription by monoclonal antibodies prepared against wheat germ RNA polymerase II that react with the heptapeptide repeat of eukaryotic RNA polymerase II. | Q44259355 | ||
Phosphorylation of RNA polymerase IIA occurs subsequent to interaction with the promoter and before the initiation of transcription | Q46409988 | ||
Promoter-dependent transcription by RNA polymerase II using immobilized enzyme complexes | Q46825216 | ||
Cloning of a subunit of yeast RNA polymerase II transcription factor b and CTD kinase | Q48158311 | ||
Promoter-dependent phosphorylation of RNA polymerase II by a template-bound kinase. Association with transcriptional initiation | Q52236882 | ||
Phosphorylation of RNA polymerase by the murine homologue of the cell-cycle control protein cdc2 | Q58997292 | ||
RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals | Q59076397 | ||
Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II | Q59098636 | ||
The transition of RNA polymerase II from initiation to elongation is associated with phosphorylation of the carboxyl-terminal domain of subunit IIa | Q64378924 | ||
HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex | Q64379078 | ||
Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA | Q67728079 | ||
RNA polymerase II carboxy-terminal domain contributes to the response to multiple acidic activators in vitro | Q67782272 | ||
DNA binding provides a signal for phosphorylation of the RNA polymerase II heptapeptide repeats | Q68074474 | ||
Phosphorylation causes a conformational change in the carboxyl-terminal domain of the mouse RNA polymerase II largest subunit | Q68187252 | ||
On the mechanisms of ku protein binding to DNA | Q68211245 | ||
Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders | Q68858908 | ||
Messenger RNA synthesis in mammalian cells is catalyzed by the phosphorylated form of RNA polymerase II | Q69222476 | ||
A protein kinase from wheat germ that phosphorylates the largest subunit of RNA polymerase II | Q69323019 | ||
5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole inhibits a HeLa protein kinase that phosphorylates an RNA polymerase II-derived peptide | Q69973755 | ||
Mechanism of interaction between Ku protein and DNA | Q70144316 | ||
P433 | issue | 24 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
nuclear antigens | Q76742702 | ||
P304 | page(s) | 11920-11924 | |
P577 | publication date | 1992-12-01 | |
1992-12-15 | |||
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II | |
P478 | volume | 89 |
Q72768377 | 10th International Conference on Methods in Protein Structure Analysis. September 8-13, 1994, Snowbird, Utah. Short communications and abstracts |
Q35997819 | A Drosophila protein homologous to the human p70 Ku autoimmune antigen interacts with the P transposable element inverted repeats |
Q38306266 | A Ku80 fragment with dominant negative activity imparts a radiosensitive phenotype to CHO-K1 cells |
Q34656593 | A central region of Ku80 mediates interaction with Ku70 in vivo |
Q32150396 | A low-pH culture condition enhances the radiosensitizing effect of wortmannin |
Q35762470 | A means to a DNA end: the many roles of Ku. |
Q36777827 | A mechanism for DNA-PK activation requiring unique contributions from each strand of a DNA terminus and implications for microhomology-mediated nonhomologous DNA end joining |
Q64388179 | A method to detect particle-specific antibodies against Ku and the DNA-dependent protein kinase catalytic subunit in autoimmune sera |
Q48002807 | A somatostatin analogue induces translocation of Ku 86 autoantigen from the cytosol to the nucleus in colon tumour cells |
Q29547883 | ATR: an essential regulator of genome integrity |
Q36364964 | Absence of autoantigen Ku in mature human neutrophils and human promyelocytic leukemia line (HL-60) cells and lymphocytes undergoing apoptosis |
Q41368190 | Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line |
Q33786814 | An alternate form of Ku80 is required for DNA end-binding activity in mammalian mitochondria |
Q36684796 | An autonomous chromatin/DNA-PK mechanism for localized DNA damage signaling in mammalian cells |
Q46107069 | Antigen receptor gene rearrangement |
Q35871672 | Attenuation of DNA-dependent protein kinase activity and its catalytic subunit by the herpes simplex virus type 1 transactivator ICP0. |
Q37353084 | Autoantibodies to DNA-dependent protein kinase. Probes for the catalytic subunit |
Q34157808 | Autoantibodies to RNA polymerase II are common in systemic lupus erythematosus and overlap syndrome. Specific recognition of the phosphorylated (IIO) form by a subset of human sera |
Q38301372 | Autoantigen Ku protein is involved in DNA binding proteins which recognize the U5 repressive element of human T-cell leukemia virus type I long terminal repeat |
Q27919629 | Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks |
Q44490255 | Bacterial and eukaryotic systems collide in the three Rs of Methanococcus. |
Q26827232 | Beyond DNA repair: DNA-PK function in cancer |
Q24678907 | Biochemical evidence for Ku-independent backup pathways of NHEJ |
Q71525106 | CPP32/Yama/apopain cleaves the catalytic component of DNA-dependent protein kinase in the holoenzyme |
Q35855807 | CREB-binding protein is a mediator of neuroblastoma cell death induced by the histone deacetylase inhibitor trichostatin A. |
Q41191958 | Characterization of a Ku86 variant protein that results in altered DNA binding and diminished DNA-dependent protein kinase activity |
Q41116291 | Characterization of two DNA double-stranded break repair-deficient cell lines that express inactive DNA-dependent protein kinase catalytic subunits |
Q28623271 | Common and unique transcription factor requirements of human U1 and U6 snRNA genes |
Q24653672 | Common mechanisms of PIKK regulation |
Q34746959 | Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen |
Q29614218 | Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage |
Q44290667 | Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment. |
Q41044013 | Cutting apart V(D)J recombination |
Q47070264 | DNA binding specificities of YPF1, a Drosophila homolog to the DNA binding subunit of human DNA-dependent protein kinase, Ku. |
Q26829155 | DNA damage response and prostate cancer: defects, regulation and therapeutic implications |
Q90055320 | DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR |
Q39876259 | DNA double-strand break repair functions defend against parvovirus infection. |
Q35965069 | DNA double-strand-break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae |
Q36144172 | DNA ends alter the molecular composition and localization of Ku multicomponent complexes |
Q28143901 | DNA ligase IV and XRCC4 form a stable mixed tetramer that functions synergistically with other repair factors in a cell-free end-joining system |
Q36126604 | DNA looping by Ku and the DNA-dependent protein kinase |
Q34880194 | DNA structure-specific priming of ATR activation by DNA-PKcs |
Q33181420 | DNA-Dependent protein kinase is not required for efficient lentivirus integration |
Q40315391 | DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner |
Q90628309 | DNA-PK, Nuclear mTOR, and the Androgen Pathway in Prostate Cancer |
Q34367487 | DNA-PK-dependent binding of DNA ends to plasmids containing nuclear matrix attachment region DNA sequences: evidence for assembly of a repair complex |
Q41513507 | DNA-PK: at the cross-roads of biochemistry and genetics |
Q38852980 | DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis |
Q35603296 | DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA. |
Q36371923 | DNA-dependent protein kinase activity is not required for immunoglobulin class switching |
Q35899741 | DNA-dependent protein kinase catalytic subunit: a target for an ICE-like protease in apoptosis |
Q64388891 | DNA-dependent protein kinase protects against heat-induced apoptosis |
Q34519398 | DNA-dependent protein kinase specifically represses promoter-directed transcription initiation by RNA polymerase I. |
Q35739034 | DNA-dependent protein kinase: DNA binding and activation in the absence of Ku |
Q37308089 | Defective signal joint recombination in fanconi anemia fibroblasts reveals a role for Rad50 in V(D)J recombination |
Q36887381 | Defining the minimal domain of Ku80 for interaction with Ku70. |
Q36430308 | Dimerization and DNA binding alter phosphorylation of Fos and Jun. |
Q44548807 | Distinct pathways of nonhomologous end joining that are differentially regulated by DNA-dependent protein kinase-mediated phosphorylation |
Q47996057 | Double-strand break repair mediated by DNA end-joining |
Q24608343 | Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications |
Q36252549 | Engagement of Components of DNA-Break Repair Complex and NFκB in Hsp70A1A Transcription Upregulation by Heat Shock |
Q34999232 | Enhancer 1 binding factor, a Ku-related protein, is a positive regulator of RNA polymerase I transcription initiation |
Q50926972 | Ensemble and Single-Molecule Analysis of Non-Homologous End Joining in Frog Egg Extracts. |
Q33702830 | Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity. |
Q24649590 | Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes |
Q36580698 | Evidence for Ku70/Ku80 association with full-length RAG1. |
Q64387979 | Expression and DNA binding activity of the Ku heterodimer in bladder carcinoma |
Q31861467 | Expression of genes involved in repair of DNA double-strand breaks in normal and tumor tissues. |
Q28284325 | Expression of human glucocorticoid receptor gene and interaction of nuclear proteins with the transcriptional control element |
Q33770481 | Functional characterization of a novel Ku70/80 pause site at the H19/Igf2 imprinting control region |
Q73877076 | Functional properties of the separate subunits of human DNA helicase II/Ku autoantigen |
Q24564348 | Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8 |
Q92513981 | Genetic expression signatures of oral submucous fibrosis and oral cancer-A preliminary microarray report |
Q52522266 | HDF2, the second subunit of the Ku homologue from Saccharomyces cerevisiae. |
Q38329558 | Hairpin coding end opening is mediated by RAG1 and RAG2 proteins |
Q39716405 | Hdf1, a yeast Ku-protein homologue, is involved in illegitimate recombination, but not in homologous recombination |
Q42800551 | Heat and chemical shock potentiation of glucocorticoid receptor transactivation requires heat shock factor (HSF) activity. Modulation of HSF by vanadate and wortmannin |
Q28250857 | Heat shock transcription factor 1 binds selectively in vitro to Ku protein and the catalytic subunit of the DNA-dependent protein kinase |
Q34626147 | Heat-shock inactivation of the TFIIH-associated kinase and change in the phosphorylation sites on the C-terminal domain of RNA polymerase II. |
Q35845807 | Herpes simplex virus immediate-early protein ICP22 is required for viral modification of host RNA polymerase II and establishment of the normal viral transcription program |
Q24336453 | Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen |
Q71143177 | Human Ku autoantigen binds cisplatin-damaged DNA but fails to stimulate human DNA-activated protein kinase |
Q64387661 | Human neutrophils isolated from peripheral blood contain Ku protein but not DNA-dependent protein kinase |
Q39576173 | Hypersensitivity of Ku-deficient cells toward the DNA topoisomerase II inhibitor ICRF-193 suggests a novel role for Ku antigen during the G2 and M phases of the cell cycle |
Q42831224 | Hypoxia-activated ligand HAL-1/13 is lupus autoantigen Ku80 and mediates lymphoid cell adhesion in vitro |
Q58244290 | Identification of Ku70/Ku80 as ADD1/SREBP1c interacting proteins |
Q36820879 | Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse |
Q34966793 | Impact of DNA ligase IV on the fidelity of end joining in human cells |
Q24294826 | In vitro and in vivo interactions of DNA ligase IV with a subunit of the condensin complex |
Q32119114 | In vitro-activated human lupus T cells express normal estrogen receptor proteins which bind to the estrogen response element |
Q39265275 | In vivo association of Ku with mammalian origins of DNA replication |
Q39945316 | Increased expression of HSP27 linked to vincristine resistance in human gastric cancer cell line |
Q39574798 | Inhibition of HTLV-1 transcription by cyclin dependent kinase inhibitors |
Q33818265 | Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs) |
Q33570316 | Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2 |
Q28608946 | Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids |
Q24290239 | Interaction of human Ku70 with TRF2 |
Q40408378 | Interactions of USF and Ku antigen with a human DNA region containing a replication origin |
Q38321453 | Involvement of DNA end-binding protein Ku in Ty element retrotransposition |
Q52519451 | Involvement of the Saccharomyces cerevisiae HDF1 gene in DNA double-strand break repair and recombination. |
Q38287589 | KAP-2, a protein that binds to the H-box in a bean chalcone synthase promoter, is a novel plant transcription factor with sequence identity to the large subunit of human Ku autoantigen |
Q24532230 | KARP-1: a novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity |
Q43613070 | Ku antigen is required to relieve G2 arrest caused by inhibition of DNA topoisomerase II activity by the bisdioxopiperazine ICRF-193. |
Q40473460 | Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells. |
Q28137885 | Ku, a DNA repair protein with multiple cellular functions? |
Q52549796 | Ku-related antigens are associated with transcriptionally active loci in Chironomus polytene chromosomes. |
Q33935153 | Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors |
Q36380622 | Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo |
Q42647102 | Ku80 facilitates chromatin binding of the telomere binding protein, TRF2 |
Q41081073 | Ku80 gene expression is Sp1-dependent and sensitive to CpG methylation within a novel cis element |
Q38337002 | Ku80 is required but not sufficient for Galpha13-mediated endodermal differentiation in P19 embryonic carcinoma cells |
Q24527652 | Ku86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response element |
Q24670086 | Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus recruits uracil DNA glycosylase 2 at the terminal repeats and is important for latent persistence of the virus |
Q78805217 | Lethality in PARP-1/Ku80 double mutant mice reveals physiological synergy during early embryogenesis |
Q34419609 | Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells |
Q28282983 | MDC1 regulates DNA-PK autophosphorylation in response to DNA damage |
Q24548851 | Mapping of protein-protein interactions within the DNA-dependent protein kinase complex |
Q41049010 | Mechanism of V(D)J recombination |
Q39982082 | Modification of the ionizing radiation response in living cells by an scFv against the DNA-dependent protein kinase |
Q37473890 | Modifying the function of DNA repair nanomachines for therapeutic benefit |
Q32082716 | Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20 |
Q40021061 | Molecular and biochemical characterization of xrs mutants defective in Ku80. |
Q40468515 | Molecular structure and function of autoantigens in systemic sclerosis. |
Q41551864 | Murine monoclonal antibodies specific for conserved and non-conserved antigenic determinants of the human and murine Ku autoantigens |
Q33854272 | Non-homologous end joining: emerging themes and unanswered questions |
Q77732947 | Nuclear extracts lacking DNA-dependent protein kinase are deficient in multiple round transcription |
Q38289667 | Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene |
Q38327349 | OBA/Ku86: DNA binding specificity and involvement in mammalian DNA replication |
Q34093159 | Phosphorylation in transcription: the CTD and more |
Q34604946 | Phosphorylation of human replication protein A by the DNA-dependent protein kinase is involved in the modulation of DNA replication |
Q36565906 | Phosphorylation of the RNA polymerase II largest subunit during Xenopus laevis oocyte maturation |
Q40401377 | Production and characterization of recombinant human Ku antigen |
Q24293029 | Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells |
Q40015992 | Proximal sequence element-binding transcription factor (PTF) is a multisubunit complex required for transcription of both RNA polymerase II- and RNA polymerase III-dependent small nuclear RNA genes |
Q30845708 | Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase |
Q24568357 | Purification of the sequence-specific transcription factor CTCBF, involved in the control of human collagen IV genes: subunits with homology to Ku antigen |
Q42099538 | RNA polymerase II C-terminal heptarepeat domain Ser-7 phosphorylation is established in a mediator-dependent fashion |
Q33905060 | RNA polymerase II carboxy-terminal domain kinases: emerging clues to their function |
Q36627034 | RNA polymerase II is aberrantly phosphorylated and localized to viral replication compartments following herpes simplex virus infection |
Q41430421 | Recent advances in understanding V(D)J recombination. |
Q40499369 | Recombination and repair. Ku starts at the end. |
Q33559700 | Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction |
Q42811268 | Reduced sulphydryl groups are required for DNA binding of Ku protein |
Q34816680 | Regulation of transcription elongation by phosphorylation |
Q35466760 | Regulatory networks integrating cell cycle control with DNA damage checkpoints and double-strand break repair |
Q71785541 | Relationship between estrogen structure and conformational changes in estrogen receptor/DNA complexes |
Q28076969 | Replication fork instability and the consequences of fork collisions from rereplication |
Q29618204 | Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair |
Q41211021 | Role of protein kinase activity in apoptosis. |
Q24561996 | Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways |
Q72180517 | Similar DNA binding properties of free P70 (KU) subunit and P70/P80 heterodimer |
Q72465867 | Stimulation of the DNA-dependent protein kinase by RNA polymerase II transcriptional activator proteins |
Q24644339 | Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4 |
Q33914715 | Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time |
Q37021606 | Structure-Specific nuclease activities of Artemis and the Artemis: DNA-PKcs complex |
Q24537786 | Subnuclear localization of Ku protein: functional association with RNA polymerase II elongation sites. |
Q38359074 | Suppression of a DNA double-strand break repair gene, Ku70, increases radio- and chemosensitivity in a human lung carcinoma cell line |
Q52558943 | TET1 deficiency attenuates the DNA damage response and promotes resistance to DNA damaging agents. |
Q38008913 | TFIIH: when transcription met DNA repair. |
Q37379581 | The 86-kD subunit of Ku autoantigen mediates homotypic and heterotypic adhesion of multiple myeloma cells |
Q24554509 | The C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit |
Q38314660 | The C-terminal conserved domain of DNA-PKcs, missing in the SCID mouse, is required for kinase activity |
Q34315021 | The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication |
Q29465403 | The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae |
Q34009427 | The DNA-damage response: new molecular insights and new approaches to cancer therapy |
Q64389407 | The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit |
Q41263744 | The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight |
Q28081821 | The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis |
Q41066922 | The DNA-dependent protein kinase: a matter of life and (cell) death |
Q37259294 | The Ku-like protein from Saccharomyces cerevisiae is required in vitro for the assembly of a stable multiprotein complex at a eukaryotic origin of replication |
Q77388156 | The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase |
Q41951178 | The integrator complex recognizes a new double mark on the RNA polymerase II carboxyl-terminal domain |
Q40406792 | The nucleolar transcription activator UBF relieves Ku antigen-mediated repression of mouse ribosomal gene transcription |
Q24310169 | The promoters for human DNA-PKcs (PRKDC) and MCM4: divergently transcribed genes located at chromosome 8 band q11 |
Q49906238 | The role of DNA-PK in aging and energy metabolism |
Q28296356 | The role of NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint control |
Q36418531 | The role of NBS1 in the modulation of PIKK family proteins ATM and ATR in the cellular response to DNA damage |
Q40639070 | The role of multisite phosphorylation in the regulation of RNA polymerase II activity |
Q41412080 | The salivary gland 42-kDa phosphoprotein is a single-stranded DNA-binding protein with characteristics of the epithelial casein kinase N42 in Chironomus tentans |
Q38196597 | The spatial organization of non-homologous end joining: from bridging to end joining |
Q40856128 | Transcription by RNA polymerase II in DNA-PK deficient scid mouse cells |
Q37082620 | Tumor Suppressors and Endodermal Differentiation of P19 Embryonic Stem Cells |
Q30729763 | Two-Stage Synapsis of DNA Ends during Non-homologous End Joining |
Q35159001 | Unique and redundant functions of ATM and DNA-PKcs during V(D)J recombination |
Q41888313 | Unwind and slow down: checkpoint activation by helicase and polymerase uncoupling |
Q36011232 | Up-regulation of the Ku heterodimer in Drosophila testicular cyst cells |
Q41134314 | V(D)J recombination pathology. |
Q34333584 | Visualization of inositol phosphate-dependent mobility of Ku: depletion of the DNA-PK cofactor InsP6 inhibits Ku mobility |
Q42850240 | Warner-Lambert/Parke-Davis Award Lecture. Pathological and physiological double-strand breaks: roles in cancer, aging, and the immune system |
Q24568188 | cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein |
Q36555430 | scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase |
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