Inositol Polyphosphate-4-Phosphatase Type I Negatively Regulates Phagocytosis via Dephosphorylation of Phagosomal PtdIns(3,4)P2.

scientific article published on 4 November 2015

Inositol Polyphosphate-4-Phosphatase Type I Negatively Regulates Phagocytosis via Dephosphorylation of Phagosomal PtdIns(3,4)P2. is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2015PLoSO..1042091N
P356DOI10.1371/JOURNAL.PONE.0142091
P932PMC publication ID4633150
P698PubMed publication ID26535897
P5875ResearchGate publication ID283499834

P2093author name stringJunko Sasaki
Takehiko Sasaki
Ying Guo
Kaoru Hazeki
Kiyomi Nigorikawa
Osamu Hazeki
Shin Morioka
Mikiko Miyake
Yumio Omori
P2860cites workThe type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membraneQ24523405
PtdIns(3,4,5)P₃ is a regulator of myosin-X localization and filopodia formation.Q52604153
Inpp5e increases the Rab5 association and phosphatidylinositol 3-phosphate accumulation at the phagosome through an interaction with Rab20Q85653698
A phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosisQ27335399
Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensorQ27674679
Myosin X is a downstream effector of PI(3)K during phagocytosisQ28114999
The effect of phosphatases SHP-1 and SHIP-1 on signaling by the ITIM- and ITAM-containing Fcgamma receptors FcgammaRIIB and FcgammaRIIAQ28207451
Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphateQ28511509
Regulated portals of entry into the cellQ29547391
Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosisQ30574571
Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signalingQ35642868
Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosisQ36293644
Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturationQ36293974
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathwayQ36320962
Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosisQ36321631
Regulation of membrane traffic by phosphoinositide 3-kinasesQ36391678
Antimicrobial mechanisms of phagocytes and bacterial evasion strategiesQ37445493
How nascent phagosomes mature to become phagolysosomesQ38007730
Phosphatidylinositol 3-kinases and their roles in phagosome maturationQ38008580
Coordination between RAB GTPase and phosphoinositide regulation and functionsQ38020744
Role of phospholipids in endocytosis, phagocytosis, and macropinocytosisQ38072901
Inositol lipid phosphatases in membrane trafficking and human disease.Q38223317
Essential roles of PIKfyve and PTEN on phagosomal phosphatidylinositol 3-phosphate dynamicsQ39258904
TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1.Q39702429
Specific role of phosphoinositide 3-kinase p110alpha in the regulation of phagocytosis and pinocytosis in macrophagesQ39825128
Critical roles of the p110 beta subtype of phosphoinositide 3-kinase in lipopolysaccharide-induced Akt activation and negative regulation of nitrite production in RAW 264.7 cells.Q40016473
Involvement of phosphatidylinositol 3-kinase in Fc gamma receptor signaling.Q41442812
The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal deathQ42171703
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectphagocytosisQ184726
P304page(s)e0142091
P577publication date2015-11-04
P1433published inPLOS OneQ564954
P1476titleInositol Polyphosphate-4-Phosphatase Type I Negatively Regulates Phagocytosis via Dephosphorylation of Phagosomal PtdIns(3,4)P2.
P478volume10

Reverse relations

cites work (P2860)
Q90597190A Phosphatidylinositol 3-Kinase Effector Alters Phagosomal Maturation to Promote Intracellular Growth of Francisella
Q96133976Endocytosis and the internalization of pathogenic organisms: focus on phosphoinositides
Q64280805Generation of endogenous pH-sensitive EGF receptor and its application in high-throughput screening for proteins involved in clathrin-mediated endocytosis
Q46383203Inhibitory receptor FcγRIIb mediates the effects of IgG on a phagosome acidification and a sequential dephosphorylation system comprising SHIPs and Inpp4a
Q40649297Myeloid cell-specific inositol polyphosphate-4-phosphatase type I knockout mice impair bacteria clearance in a murine peritonitis model

Search more.