| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Roopa Thapar | |
| P2860 | cites work | U box proteins as a new family of ubiquitin-protein ligases | Q24291397 |
| The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae | Q24293963 | ||
| Hsp90 cochaperones p23 and FKBP4 physically interact with hAgo2 and activate RNA interference-mediated silencing in mammalian cells | Q24294644 | ||
| The N-terminal basic domain of human parvulin hPar14 is responsible for the entry to the nucleus and high-affinity DNA-binding | Q24302291 | ||
| CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1 | Q24303611 | ||
| Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60 | Q24305042 | ||
| The crystal structure of PPIL1 bound to cyclosporine A suggests a binding mode for a linear epitope of the SKIP protein | Q24305898 | ||
| Dynamic protein-protein interaction wiring of the human spliceosome | Q24306136 | ||
| The 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteins | Q24312016 | ||
| A Pin1/mutant p53 axis promotes aggressiveness in breast cancer | Q24312083 | ||
| The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils. | Q52034778 | ||
| The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes. | Q53590097 | ||
| The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes | Q69079614 | ||
| Pinning down transcription: regulation of RNA polymerase II activity during the cell cycle | Q75320782 | ||
| A universal RNA polymerase II CTD cycle is orchestrated by complex interplays between kinase, phosphatase, and isomerase enzymes along genes | Q83344227 | ||
| Transcriptional coregulator SNW/SKIP: the concealed tie of dissimilar pathways | Q35723601 | ||
| A structural perspective of CTD function | Q36167411 | ||
| Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis | Q36330861 | ||
| Targeting carcinogenesis: a role for the prolyl isomerase Pin1? | Q36465488 | ||
| Identification of RNA targets for the nuclear multidomain cyclophilin atCyp59 and their effect on PPIase activity. | Q36580971 | ||
| Pinning down signaling in the immune system: the role of the peptidyl-prolyl isomerase Pin1 in immune cell function | Q37093918 | ||
| Chromatin structure and the inheritance of epigenetic information | Q37141498 | ||
| The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly | Q37365349 | ||
| The prolyl isomerase pin1 regulates mRNA levels of genes with short half-lives by targeting specific RNA binding proteins | Q37458768 | ||
| Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis | Q37485770 | ||
| Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast. | Q37606424 | ||
| "Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions | Q37620941 | ||
| The role of KSRP in mRNA decay and microRNA precursor maturation | Q37936370 | ||
| Functional diversity and pharmacological profiles of the FKBPs and their complexes with small natural ligands | Q38065993 | ||
| Hsp90-binding immunophilins as a potential new platform for drug treatment | Q38097870 | ||
| Interpreting the language of histone and DNA modifications | Q38196193 | ||
| Emerging mechanisms of mRNP remodeling regulation | Q38219824 | ||
| The role of immunophilins in viral infection | Q38274889 | ||
| AtCyp59 is a multidomain cyclophilin from Arabidopsis thaliana that interacts with SR proteins and the C-terminal domain of the RNA polymerase II. | Q38315524 | ||
| Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease | Q38316418 | ||
| Peptidyl-prolyl isomerases: a full cast of critical actors in cardiovascular diseases. | Q38370240 | ||
| Pin1: Intimate involvement with the regulatory protein kinase networks in the global phosphorylation landscape | Q38376214 | ||
| Targeting the chemotactic function of CD147 reduces collagen-induced arthritis | Q38961065 | ||
| Rapamycin-binding FKBP25 associates with diverse proteins that form large intracellular entities | Q38977720 | ||
| Pin1 modulates RNA polymerase II activity during the transcription cycle | Q39258906 | ||
| Alzheimer's disease-related loss of Pin1 function influences the intracellular localization and the processing of AβPP. | Q39376827 | ||
| Cyclophilin, a primary molecular target for cyclosporine. Structural and functional implications | Q39516228 | ||
| The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism. | Q39796772 | ||
| Pin1 modulates the structure and function of human RNA polymerase II. | Q40266169 | ||
| Consideration of the possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues | Q40346399 | ||
| Regulation of Raf-1 by direct feedback phosphorylation. | Q40467820 | ||
| Binding of a putative and a known chaperone protein revealed by immunogold labeling transmission electron microscopy: A suggested use of chaperones as probes for the distribution of their target proteins. | Q40917262 | ||
| The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes. | Q41238756 | ||
| Functional interaction of the Ess1 prolyl isomerase with components of the RNA polymerase II initiation and termination machineries | Q41837167 | ||
| Interdomain interactions support interdomain communication in human Pin1 | Q42126679 | ||
| Pin1-based diagnostic and therapeutic strategies for breast cancer | Q42470945 | ||
| Pin1 regulates parathyroid hormone mRNA stability | Q42566449 | ||
| PTF1 encodes an essential protein in Saccharomyces cerevisiae, which shows strong homology with a new putative family of PPIases | Q42686220 | ||
| Flipping MLL1's switch one proline at a time | Q42984901 | ||
| The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response. | Q44192183 | ||
| The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer. | Q44618217 | ||
| Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A | Q46979889 | ||
| Peptide binding induces large scale changes in inter-domain mobility in human Pin1. | Q47986427 | ||
| The cyclophilin inhibitor Debio 025 combined with PEG IFNalpha2a significantly reduces viral load in treatment-naïve hepatitis C patients. | Q48033815 | ||
| The significance of Pin1 in the development of Alzheimer's disease | Q48241525 | ||
| Human CyP33 binds specifically to mRNA and binding stimulates PPIase activity of hCyP33. | Q50320372 | ||
| Isolation of an active step I spliceosome and composition of its RNP core | Q50336090 | ||
| Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP | Q24314428 | ||
| Parvulin (Par14), a peptidyl-prolyl cis-trans isomerase, is a novel rRNA processing factor that evolved in the metazoan lineage | Q24315973 | ||
| Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression | Q24319024 | ||
| A serine/arginine-rich nuclear matrix cyclophilin interacts with the C-terminal domain of RNA polymerase II | Q24322515 | ||
| Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1. | Q24535558 | ||
| The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1. | Q24535726 | ||
| A cyclophilin functions in pre-mRNA splicing | Q24536168 | ||
| Combined top-down and bottom-up proteomics identifies a phosphorylation site in stem-loop-binding proteins that contributes to high-affinity RNA binding | Q24541504 | ||
| Two protein-protein interaction sites on the spliceosome-associated human cyclophilin CypH | Q24670824 | ||
| Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins | Q26825421 | ||
| Prolyl isomerase Pin1 in cancer | Q27024695 | ||
| Crystal structure of the human U4/U6 small nuclear ribonucleoprotein particle-specific SnuCyp-20, a nuclear cyclophilin | Q27621706 | ||
| NMR solution structure of hPar14 reveals similarity to the peptidyl prolyl cis/trans isomerase domain of the mitotic regulator hPin1 but indicates a different functionality of the protein | Q27626801 | ||
| Solution structure of the human parvulin-like peptidyl prolyl cis/trans isomerase, hPar14 | Q27629310 | ||
| Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide | Q27641709 | ||
| Structural Basis for High-Affinity Peptide Inhibition of Human Pin1 | Q27644848 | ||
| The crystal structure of human WD40 repeat-containing peptidylprolyl isomerase (PPWD1) | Q27650272 | ||
| Solution structure of the parvulin-type PPIase domain of Staphylococcus aureus PrsA – Implications for the catalytic mechanism of parvulins | Q27654271 | ||
| Structure-based design of novel human Pin1 inhibitors (I) | Q27657296 | ||
| Structure-based design of novel human Pin1 inhibitors (II) | Q27660130 | ||
| Molecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM Domain | Q27661492 | ||
| The PHD3 Domain of MLL Acts as a CYP33-Regulated Switch between MLL-Mediated Activation and Repression, | Q27663805 | ||
| Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution | Q27664950 | ||
| cis -Proline-mediated Ser(P) 5 Dephosphorylation by the RNA Polymerase II C-terminal Domain Phosphatase Ssu72 | Q27666319 | ||
| Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90 | Q27668151 | ||
| Crystallographic proof for an extended hydrogen-bonding network in small prolyl isomerases | Q27675563 | ||
| Interaction of the Histone mRNA Hairpin with Stem–Loop Binding Protein (SLBP) and Regulation of the SLBP–RNA Complex by Phosphorylation and Proline Isomerization | Q27678159 | ||
| Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code | Q27679514 | ||
| Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent | Q27739821 | ||
| Bur1 kinase is required for efficient transcription elongation by RNA polymerase II. | Q27930313 | ||
| The Ess1 prolyl isomerase is required for transcription termination of small noncoding RNAs via the Nrd1 pathway | Q27931668 | ||
| The FK506-binding protein, Fpr4, is an acidic histone chaperone | Q27932377 | ||
| The Ess1 prolyl isomerase is linked to chromatin remodeling complexes and the general transcription machinery | Q27932954 | ||
| Proline isomerization of histone H3 regulates lysine methylation and gene expression | Q27933713 | ||
| Dimethylation of H3K4 by Set1 recruits the Set3 histone deacetylase complex to 5' transcribed regions | Q27936392 | ||
| Ssu72 Is an RNA polymerase II CTD phosphatase | Q27936648 | ||
| Mutations in a peptidylprolyl-cis/trans-isomerase gene lead to a defect in 3'-end formation of a pre-mRNA in Saccharomyces cerevisiae | Q27938389 | ||
| Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3'-End formation | Q27938452 | ||
| A human peptidyl-prolyl isomerase essential for regulation of mitosis | Q28117639 | ||
| Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription | Q28131686 | ||
| The spliceosome: design principles of a dynamic RNP machine | Q28131809 | ||
| Phosphorylation of the N-terminal domain regulates subcellular localization and DNA binding properties of the peptidyl-prolyl cis/trans isomerase hPar14 | Q28187175 | ||
| Comprehensive proteomic analysis of the human spliceosome | Q28201545 | ||
| Molecular cloning and characterization of a novel peptidylprolyl isomerase (cyclophilin)-like gene (PPIL3) from human fetal brain | Q28204559 | ||
| Isolation and proteomic characterization of human Parvulin-associating preribosomal ribonucleoprotein complexes | Q28215155 | ||
| Structure of recombinant human cyclophilin J, a novel member of the cyclophilin family | Q28237097 | ||
| Functional aspects of extracellular cyclophilins | Q28237777 | ||
| 1.88 A crystal structure of the C domain of hCyP33: a novel domain of peptidyl-prolyl cis-trans isomerase | Q28257244 | ||
| The prolyl isomerase Pin1 targets stem-loop binding protein (SLBP) to dissociate the SLBP-histone mRNA complex linking histone mRNA decay with SLBP ubiquitination | Q28273385 | ||
| Upstream and downstream of mTOR | Q28277365 | ||
| Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes | Q28277749 | ||
| RS cyclophilins: identification of an NK-TR1-related cyclophilin | Q28299895 | ||
| A nuclear RNA-binding cyclophilin in human T cells | Q28300122 | ||
| Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain | Q28343959 | ||
| A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing | Q28511456 | ||
| Matrin CYP, an SR-rich cyclophilin that associates with the nuclear matrix and splicing factors | Q28577033 | ||
| Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin | Q28586339 | ||
| A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR | Q28910448 | ||
| An extensive network of coupling among gene expression machines | Q29547273 | ||
| Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity | Q29555842 | ||
| RNA polymerase II and the integration of nuclear events | Q29614772 | ||
| From birth to death: the complex lives of eukaryotic mRNAs | Q29615021 | ||
| Cyclophilin: a specific cytosolic binding protein for cyclosporin A | Q29620548 | ||
| Multidomain Peptidyl Prolyl cis/trans Isomerases | Q30316949 | ||
| On the benefit of bivalency in peptide ligand/pin1 interactions | Q30319749 | ||
| Insights into the catalytic mechanism of peptidyl prolyl cis/trans isomerases | Q30320453 | ||
| Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation | Q30885629 | ||
| A genome wide analysis of ubiquitin ligases in APP processing identifies a novel regulator of BACE1 mRNA levels | Q33257770 | ||
| The loss of PIN1 deregulates cyclin E and sensitizes mouse embryo fibroblasts to genomic instability | Q33292394 | ||
| KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells | Q33506175 | ||
| The Ess1 prolyl isomerase: traffic cop of the RNA polymerase II transcription cycle | Q33726010 | ||
| DSIF and RNA Polymerase II CTD Phosphorylation Coordinate the Recruitment of Rpd3S to Actively Transcribed Genes | Q33742112 | ||
| Extracellular cyclophilins contribute to the regulation of inflammatory responses | Q33821920 | ||
| Identification of eukaryotic parvulin homologues: a new subfamily of peptidylprolyl cis-trans isomerases | Q33864532 | ||
| Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin | Q33911404 | ||
| The prolyl isomerase, FKBP25, interacts with RNA-engaged nucleolin and the pre-60S ribosomal subunit. | Q33967912 | ||
| Phosphorylated Pol II CTD Recruits Multiple HDACs, Including Rpd3C(S), for Methylation-Dependent Deacetylation of ORF Nucleosomes | Q34118607 | ||
| 3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex | Q34375305 | ||
| Hyperphosphorylation of the C-terminal repeat domain of RNA polymerase II facilitates dissociation of its complex with mediator | Q34610960 | ||
| Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis | Q34743616 | ||
| Pin1 inhibitors: Pitfalls, progress and cellular pharmacology | Q34782041 | ||
| Immunity, microbial pathogenesis, and immunophilins: finding the keys, now where are the locks? | Q35174939 | ||
| The spliceosomal PRP19 complex of trypanosomes | Q35218927 | ||
| Prolyl isomerases in gene transcription | Q35561852 | ||
| P275 | copyright license | Creative Commons Attribution | Q6905323 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 2 | |
| P921 | main subject | enzyme | Q8047 |
| regulation of gene expression | Q411391 | ||
| post-transcriptional modification | Q417379 | ||
| P304 | page(s) | 974-999 | |
| P577 | publication date | 2015-05-18 | |
| P1433 | published in | Biomolecules | Q23929963 |
| P1476 | title | Roles of Prolyl Isomerases in RNA-Mediated Gene Expression | |
| P478 | volume | 5 |
| Q88774997 | Changes in Corticotrope Gene Expression Upon Increased Expression of Peptidylglycine α-Amidating Monooxygenase |
| Q64243325 | Compression of Large Sets of Sequence Data Reveals Fine Diversification of Functional Profiles in Multigene Families of Proteins: A Study for Peptidyl-Prolyl Isomerases (PPIase) |
| Q93088770 | Enzyme activity and structural features of three single-domain phloem cyclophilins from Brassica napus |
| Q48123961 | Evolutionary analysis of polyproline motifs in Escherichia coli reveals their regulatory role in translation |
| Q35959194 | Mycobacterium tuberculosis Peptidyl-Prolyl Isomerases Also Exhibit Chaperone like Activity In-Vitro and In-Vivo |
| Q64072057 | Pleiotropic Cyclophilin PpiB Controls Cysteine-Tolerance, Toxin Production, the Central Metabolism and Multiple Stress Responses |
| Q91975825 | Prolyl Isomerase Pin1 in Human Cancer: Function, Mechanism, and Significance |
| Q33597735 | RNA interference-mediated gene silencing of cyclophilin A enhances the radiosensitivity of PAa human lung adenocarcinoma cells in vitro |
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