IDH mutations in primary myelofibrosis predict leukemic transformation and shortened survival: clinical evidence for leukemogenic collaboration with JAK2V617F

scientific article published on 13 September 2011

IDH mutations in primary myelofibrosis predict leukemic transformation and shortened survival: clinical evidence for leukemogenic collaboration with JAK2V617F is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1017042221
P356DOI10.1038/LEU.2011.253
P932PMC publication ID3306137
P698PubMed publication ID21912393
P5875ResearchGate publication ID51632498

P50authorAyalew TefferiQ66370740
P2093author name stringA Pardanani
T L Lasho
C M Finke
R A Knudson
N H Sulai
R F McClure
T Jimma
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IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplicationQ43010371
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IDH1 and IDH2 mutation analysis in chronic- and blast-phase myeloproliferative neoplasms.Q43089505
Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasmsQ43106526
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Risk factors for leukemic transformation in patients with primary myelofibrosisQ46650489
Leukemic blasts in transformed JAK2-V617F-positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation.Q51761197
JAK2 germline genetic variation affects disease susceptibility in primary myelofibrosis regardless of V617F mutational status: nullizygosity for the JAK2 46/1 haplotype is associated with inferior survival.Q53185401
Deletions of the transcription factor Ikaros in myeloproliferative neoplasms.Q54426186
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IDH2 somatic mutations in chronic myeloid leukemia patients in blast crisisQ58023817
A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment).Q61050093
Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survivalQ80542642
Leukemic transformation in myelofibrosis with myeloid metaplasia: a single-institution experience with 91 casesQ80607021
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
collaborationQ1145523
myelofibrosisQ1752571
chronic idiopathic myelofibrosisQ3857106
P304page(s)475-480
P577publication date2011-09-13
P1433published inLeukemiaQ6534498
P1476titleIDH mutations in primary myelofibrosis predict leukemic transformation and shortened survival: clinical evidence for leukemogenic collaboration with JAK2V617F
P478volume26

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