Identification of a nuclear localization sequence in β-arrestin-1 and its functional implications

scientific article published on 21 January 2012

Identification of a nuclear localization sequence in β-arrestin-1 and its functional implications is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M111.294058
P932PMC publication ID3308787
P698PubMed publication ID22267743
P5875ResearchGate publication ID221768764

P50authorRichard D YeQ38545206
P2093author name stringNi Cheng
Crystal Zoe Hoeppner
P2860cites workTranscriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)Q24297420
A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcriptionQ24297869
Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signalingQ24299892
beta-Arrestin: a protein that regulates beta-adrenergic receptor functionQ24305145
An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behaviorQ24310712
Functional specialization of beta-arrestin interactions revealed by proteomic analysisQ24318455
Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathwaysQ24338654
Multiple pathways contribute to nuclear import of core histonesQ24522562
Rules for nuclear localization sequence recognition by karyopherin beta 2Q24600321
Crystal structure of beta-arrestin at 1.9 A: possible mechanism of receptor binding and membrane TranslocationQ27634946
Crystal Structure of Arrestin-3 Reveals the Basis of the Difference in Receptor Binding Between Two Non-visual SubtypesQ27666519
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
Characterization of karyopherin cargoes reveals unique mechanisms of Kap121p-mediated nuclear importQ27934921
NF-kappaB RelA phosphorylation regulates RelA acetylationQ28115098
Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.Q28118359
Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3Q28138462
beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosisQ28141212
Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminusQ28204316
Duration of nuclear NF-kappaB action regulated by reversible acetylationQ28215080
Good cop, bad cop: the different faces of NF-kappaBQ28291669
Beta-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2Q28359741
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequenceQ29547917
Molecular mechanism of the nuclear protein import cycleQ29617058
Sequence requirements for nuclear location of simian virus 40 large-T antigenQ29620588
Regulation of nuclear localization: a key to a doorQ33804320
Nucleocytoplasmic protein transport and recycling of Ran.Q33852560
Crossing the nuclear envelope: hierarchical regulation of nucleocytoplasmic transportQ34008468
Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein)Q34376629
beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha.Q34513767
Identification of domains involved in nuclear uptake and histone binding of protein N1 of Xenopus laevisQ36063975
Visual and both non-visual arrestins in their "inactive" conformation bind JNK3 and Mdm2 and relocalize them from the nucleus to the cytoplasmQ36726881
Beta-arrestin 2 is required for lysophosphatidic acid-induced NF-kappaB activationQ36964334
Nuclear translocation of viral Jun but not of cellular Jun is cell cycle dependentQ37001181
The 27-kDa heat shock protein confers cytoprotective effects through a beta 2-adrenergic receptor agonist-initiated complex with beta-arrestinQ37199137
beta-Arrestin1 interacts with the G-protein subunits beta1gamma2 and promotes beta1gamma2-dependent Akt signalling for NF-kappaB activationQ37350606
Bradykinin stimulates NF-kappaB activation and interleukin 1beta gene expression in cultured human fibroblastsQ37361105
Nuclear beta-arrestin1 functions as a scaffold for the dephosphorylation of STAT1 and moderates the antiviral activity of IFN-gammaQ39942696
Identification of a functional bipartite nuclear localization signal in the tumor suppressor parafibrominQ40382150
Molecular dissection of the nuclear pore complexQ41063786
Arrestin orchestrates crosstalk between G protein-coupled receptors to modulate the spatiotemporal activation of ERK MAPK.Q41865336
Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2.Q44094517
Nuclear translocation of plk1 mediated by its bipartite nuclear localization signalQ44167900
Requirement of Gbetagamma and c-Src in D2 dopamine receptor-mediated nuclear factor-kappaB activationQ44517638
β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosisQ44610984
Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate bindingQ46913508
The nuclear pore complexQ71778522
The human tap nuclear RNA export factor contains a novel transportin-dependent nuclear localization signal that lacks nuclear export signal functionQ73133774
Dissection of the karyopherin alpha nuclear localization signal (NLS)-binding groove: functional requirements for NLS bindingQ73806566
Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophagesQ80276238
Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1Q80584784
P4510describes a project that usesImageJQ1659584
P433issue12
P407language of work or nameEnglishQ1860
P1104number of pages12
P304page(s)8932-8943
P577publication date2012-01-21
P1433published inJournal of Biological ChemistryQ867727
P1476titleIdentification of a nuclear localization sequence in β-arrestin-1 and its functional implications
P478volume287

Reverse relations

cites work (P2860)
Q36923552Angiotensin II activates NF-κB through AT1A receptor recruitment of β-arrestin in cultured rat vascular smooth muscle cells
Q87537652Arrestin2 modulates androgen receptor activation
Q42089456Arrestins in apoptosis
Q36205804Astroglial β-Arrestin1-mediated Nuclear Signaling Regulates the Expansion of Neural Precursor Cells in Adult Hippocampus
Q90029966CCR2 Signaling Selectively Regulates IFN-α: Role of β-Arrestin 2 in IFNAR1 Internalization
Q41143599Co-expression of β-arrestin1 and NF-кB is associated with cancer progression and poor prognosis in lung adenocarcinoma
Q34472138Distinct cellular and subcellular distributions of G protein-coupled receptor kinase and arrestin isoforms in the striatum
Q47910938G protein coupled-receptor signaling and reversible lysine acetylation
Q64229777New Routes in GPCR/β-Arrestin-Driven Signaling in Cancer Progression and Metastasis
Q45680294Subcellular localization of β-arrestin1 and its prognostic value in lung adenocarcinoma
Q48010163Targeting endothelin-1 receptor/β-arrestin1 network for the treatment of ovarian cancer
Q39381430The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling
Q44686499β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling.
Q26740489β-arrestin1 at the cross-road of endothelin-1 signaling in cancer
Q92034546β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer
Q33676791βArrestin1 regulates the guanine nucleotide exchange factor RasGRF2 expression and the small GTPase Rac-mediated formation of membrane protrusion and cell motility

Search more.