| scholarly article | Q13442814 |
| P2093 | author name string | Aparna Kaul | |
| William A Maltese | |||
| Jean H Overmeyer | |||
| P2860 | cites work | The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 |
| Protein binding and signaling properties of RIN1 suggest a unique effector function | Q24319548 | ||
| Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors | Q24534185 | ||
| Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation | Q24563004 | ||
| Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors | Q24601002 | ||
| Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis | Q27674619 | ||
| Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules | Q27674981 | ||
| Mammalian Ras interacts directly with the serine/threonine kinase Raf | Q27860833 | ||
| Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells | Q28138966 | ||
| Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi | Q28140190 | ||
| RLIP76, an effector of the GTPase Ral, interacts with the AP2 complex: involvement of the Ral pathway in receptor endocytosis | Q28141762 | ||
| The pro-apoptotic Ras effector Nore1 may serve as a Ras-regulated tumor suppressor in the lung | Q28188823 | ||
| Identification of a novel Ras-regulated proapoptotic pathway | Q28203664 | ||
| Ral GTPases regulate exocyst assembly through dual subunit interactions | Q28207098 | ||
| Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras | Q28238120 | ||
| Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization | Q28251364 | ||
| Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking | Q28289648 | ||
| A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases | Q29040265 | ||
| ras oncogenes in human cancer: a review | Q29547769 | ||
| Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells | Q29614181 | ||
| Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells | Q48211866 | ||
| Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis | Q48959027 | ||
| Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. | Q50537316 | ||
| Increasing complexity of Ras signaling. | Q53429989 | ||
| Biological and biochemical properties of human rasH genes mutated at codon 61. | Q53538669 | ||
| Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway. | Q53600237 | ||
| The effect of wortmannin on the localisation of lysosomal type I integral membrane glycoproteins suggests a role for phosphoinositide 3-kinase activity in regulating membrane traffic late in the endocytic pathway | Q71287476 | ||
| Different structural requirements within the switch II region of the Ras protein for interactions with specific downstream targets | Q71946178 | ||
| Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase | Q77195536 | ||
| Increased Ras expression and caspase-independent neuroblastoma cell death: possible mechanism of spontaneous neuroblastoma regression | Q77733241 | ||
| Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane | Q29618478 | ||
| Phosphatidylinositol-3-OH kinase as a direct target of Ras | Q29620177 | ||
| A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles | Q32046208 | ||
| The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway | Q33599964 | ||
| Caspase-independent programmed cell death with necrotic morphology | Q33669492 | ||
| Understanding Ras: 'it ain't over 'til it's over'. | Q33877218 | ||
| Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. | Q34101310 | ||
| Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism | Q34140558 | ||
| Multiple Ras functions can contribute to mammalian cell transformation | Q34319284 | ||
| Identification of AF-6 and canoe as putative targets for Ras. | Q34371134 | ||
| AF6 negatively regulates Rap1-induced cell adhesion | Q34438021 | ||
| Ras pathway signaling on endomembranes | Q35089365 | ||
| Ras proteins: different signals from different locations | Q35120159 | ||
| Ral-GTPases: approaching their 15 minutes of fame | Q35187818 | ||
| The dark side of Ras: regulation of apoptosis | Q35603375 | ||
| Autophagy as a cell death and tumor suppressor mechanism | Q35743138 | ||
| Apoptosis, autophagy, and more | Q35869374 | ||
| Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis | Q36084509 | ||
| Direct visualization of Ras proteins in spatially distinct cell surface microdomains | Q36322914 | ||
| Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation | Q36561047 | ||
| The ras protein family: evolutionary tree and role of conserved amino acids | Q37713543 | ||
| Peptides containing a consensus Ras binding sequence from Raf-1 and theGTPase activating protein NF1 inhibit Ras function | Q37720942 | ||
| Evidence for a dual control of macroautophagic sequestration and intracellular trafficking of N-linked glycoproteins by the trimeric G(i3) protein in HT-29 cells. | Q38345105 | ||
| Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity | Q40259774 | ||
| Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes | Q40307780 | ||
| Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells | Q40600919 | ||
| Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells | Q40667540 | ||
| The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway | Q40789651 | ||
| GTP-dependent segregation of H-ras from lipid rafts is required for biological activity | Q40815505 | ||
| Function and regulation of ras. | Q40835314 | ||
| Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate | Q40886507 | ||
| Rab24 is an atypical member of the Rab GTPase family. Deficient GTPase activity, GDP dissociation inhibitor interaction, and prenylation of Rab24 expressed in cultured cells | Q40902023 | ||
| Structural requirements for the interaction of p21ras with GAP, exchange factors, and its biological effector target | Q40903747 | ||
| Posttranslational processing of the ras superfamily of small GTP-binding proteins | Q40912806 | ||
| Oncogenic Ki-ras but not oncogenic Ha-ras blocks integrin beta1-chain maturation in colon epithelial cells | Q41072474 | ||
| Association of Rab1B with GDP-dissociation inhibitor (GDI) is required for recycling but not initial membrane targeting of the Rab protein | Q41199490 | ||
| Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS. | Q41228912 | ||
| Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors | Q42813152 | ||
| Ras signalling on the endoplasmic reticulum and the Golgi | Q42815732 | ||
| Plasma membrane recruitment of RalGDS is critical for Ras-dependent Ral activation | Q42819395 | ||
| The linker domain of the Ha-Ras hypervariable region regulates interactions with exchange factors, Raf-1 and phosphoinositide 3-kinase | Q43786808 | ||
| Akt protein kinase inhibits non-apoptotic programmed cell death induced by ceramide | Q43797740 | ||
| Induction of autophagic cell death in malignant glioma cells by arsenic trioxide. | Q44427360 | ||
| Essential role for Ras signaling in glioblastoma maintenance | Q44870848 | ||
| Cell death: programmed, apoptosis, necrosis, or other? | Q47899147 | ||
| Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines | Q48154511 | ||
| P433 | issue | 5 | |
| P921 | main subject | glioblastoma | Q282142 |
| apoptotic process | Q14599311 | ||
| P1104 | number of pages | 10 | |
| P304 | page(s) | 1034-1043 | |
| P577 | publication date | 2006-11-28 | |
| P1433 | published in | Cellular Signalling | Q1524097 |
| P1476 | title | Activated Ras induces cytoplasmic vacuolation and non-apoptotic death in glioblastoma cells via novel effector pathways | |
| P478 | volume | 19 |
| Q30501296 | A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells |
| Q34268342 | A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism |
| Q34365378 | Active ras triggers death in glioblastoma cells through hyperstimulation of macropinocytosis |
| Q34568628 | Anti-tumor effect of a novel PI3-kinase inhibitor, SF1126, in (12) V-Ha-Ras transgenic mouse glioma model |
| Q37694869 | CD99 triggering induces methuosis of Ewing sarcoma cells through IGF-1R/RAS/Rac1 signaling |
| Q26743410 | Cytoplasmic vacuolization in cell death and survival |
| Q34994888 | Death pathways triggered by activated Ras in cancer cells |
| Q51746207 | Evaluating vacquinol-1 in rats carrying glioblastoma models RG2 and NS1. |
| Q28306273 | Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells |
| Q81251105 | Formation of large vacuoles induced by cooperative effects of oncostatin M and dexamethasone in human fetal liver cells |
| Q50140924 | Induction of Non-Apoptotic Programmed Cell Death by Oncogenic RAS in Human Epithelial Cells and Its Suppression by MYC Overexpression |
| Q34365365 | Induction of nonapoptotic cell death by activated Ras requires inverse regulation of Rac1 and Arf6 |
| Q27692058 | Methuosis: nonapoptotic cell death associated with vacuolization of macropinosome and endosome compartments |
| Q38374734 | Non-apoptotic cell death associated with perturbations of macropinocytosis |
| Q35127614 | RETRACTED: Vulnerability of glioblastoma cells to catastrophic vacuolization and death induced by a small molecule |
| Q34183909 | Raf/MEK/ERK can regulate cellular levels of LC3B and SQSTM1/p62 at expression levels |
| Q38752941 | Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells |
| Q88433909 | [Mechanism of Platycarya strobilacea Sieb. et Zucc extract-induced methuosis in human nasopharyngeal carcinoma CNE1 and CNE2 cells] |
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