scholarly article | Q13442814 |
P50 | author | Erwin G. Van Meir | Q30503507 |
P2093 | author name string | M Tada | |
N Ishii | |||
D Maier | |||
A Merlo | |||
Y Sawamura | |||
A C Diserens | |||
P2860 | cites work | The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 |
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways | Q24321528 | ||
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53 | Q28266637 | ||
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest | Q28270478 | ||
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF | Q29619663 | ||
A simple p53 functional assay for screening cell lines, blood, and tumors | Q34397902 | ||
Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF. | Q35960464 | ||
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain | Q36818855 | ||
Genetic alterations associated with the evolution and progression of astrocytic brain tumours | Q40427187 | ||
Field cancerisation and polyclonal p53 mutation in the upper aero- digestive tract | Q54953383 | ||
Frequent loss of the cyclin-dependent kinase-4 inhibitor gene in human gliomas. | Q55021597 | ||
PTEN/MMAC1 mutations in primary glioblastomas and short-term cultures of malignant gliomas. | Q55477977 | ||
Hemizygous or homozygous deletion of the chromosomal region containing the p16INK4a gene is associated with amplification of the EGF receptor gene in glioblastomas. | Q55478215 | ||
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers | Q55480673 | ||
Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus | Q57269211 | ||
Genetic instability leads to loss of both p53 alleles in a human glioblastoma | Q41064852 | ||
p53 protein accumulation and gene mutations in human glioma cell lines | Q41509767 | ||
Morphological, immunocytochemical and growth characteristics of three human glioblastomas established in vitro | Q41706700 | ||
Establishment and characterization of five cell lines derived from human malignant gliomas | Q42817353 | ||
Constitutional p53 mutations associated with brain tumors in young adults | Q46575531 | ||
PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas | Q47740646 | ||
Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliomas | Q47775705 | ||
Absence of p53 gene mutations in a tumor panel representative of pilocytic astrocytoma diversity using a p53 functional assay | Q47975834 | ||
PTEN mutations in gliomas and glioneuronal tumors. | Q47995275 | ||
Subsets of glioblastoma multiforme defined by molecular genetic analysis | Q48379049 | ||
Intrinsic brain-stem tumors of childhood: surgical indications | Q48391525 | ||
Clonality and stability of the p53 gene in human astrocytic tumor cells: quantitative analysis of p53 gene mutations by yeast functional assay | Q48960481 | ||
Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas | Q48972634 | ||
P4510 | describes a project that uses | U-87MG ATCC | Q7863603 |
LN-340 | Q54902777 | ||
LN-382T | Q54902779 | ||
LN-401 | Q54902780 | ||
LN-405 | Q54902781 | ||
LN-427 | Q54902782 | ||
LN-428 | Q54902783 | ||
LN-443 | Q54902784 | ||
LN-444 | Q54902785 | ||
LN-464 | Q54902786 | ||
LN-71 | Q54902788 | ||
LN-751 | Q54902789 | ||
LN-827 | Q54902792 | ||
LN-859 | Q54902793 | ||
LN-992 | Q54902794 | ||
SF188 | Q54952896 | ||
SF763 | Q54952932 | ||
SF767 | Q54952933 | ||
U-118MG | Q54973503 | ||
U-138MG | Q54973513 | ||
U-178MG | Q54973519 | ||
U-251MG | Q54973550 | ||
U-343MG | Q54973568 | ||
U-373MG ATCC | Q54973575 | ||
T98G | Q52609889 | ||
A-172 | Q54605968 | ||
D-247MG | Q54817124 | ||
Hs 683 | Q54895882 | ||
LN-18 | Q54902768 | ||
LN-215 | Q54902769 | ||
LN-229 | Q54902771 | ||
LN-235 | Q54902773 | ||
LN-308 | Q54902775 | ||
LN-319 | Q54902776 | ||
P433 | issue | 3 | |
P921 | main subject | cell line | Q21014462 |
P304 | page(s) | 469-479 | |
P577 | publication date | 1999-07-01 | |
P1433 | published in | Brain Pathology | Q4955776 |
P1476 | title | Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines | |
P478 | volume | 9 |
Q54605968 | A-172 |
Q54817124 | D-247MG |
Q54895882 | Hs 683 |
Q54902768 | LN-18 |
Q54902769 | LN-215 |
Q54902771 | LN-229 |
Q54902773 | LN-235 |
Q54902775 | LN-308 |
Q54902776 | LN-319 |
Q54902777 | LN-340 |
Q54902779 | LN-382T |
Q54902780 | LN-401 |
Q54902781 | LN-405 |
Q54902782 | LN-427 |
Q54902783 | LN-428 |
Q54902784 | LN-443 |
Q54902785 | LN-444 |
Q54902786 | LN-464 |
Q54902788 | LN-71 |
Q54902789 | LN-751 |
Q54902792 | LN-827 |
Q54902793 | LN-859 |
Q54902794 | LN-992 |
Q54952896 | SF188 |
Q54952932 | SF763 |
Q54952933 | SF767 |
Q52609889 | T98G |
Q54973503 | U-118MG |
Q54973513 | U-138MG |
Q54973519 | U-178MG |
Q54973550 | U-251MG |
Q54973568 | U-343MG |
Q54973575 | U-373MG ATCC |
Q7863603 | U-87MG ATCC |
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Q39954297 | Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins |
Q36212896 | Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240. |
Q33644048 | Restoration of endogenous wild-type p53 activity in a glioblastoma cell line with intrinsic temperature-sensitive p53 induces growth arrest but not apoptosis |
Q28750173 | Retracted: Differential SELEX in Human Glioma Cell Lines |
Q92966660 | Rodent Glioma Models: Intracranial Stereotactic Allografts and Xenografts |
Q41917289 | SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans |
Q38903930 | STAT3 Serine 727 Phosphorylation: A Relevant Target to Radiosensitize Human Glioblastoma. |
Q34277050 | Scatter factor/hepatocyte growth factor stimulation of glioblastoma cell cycle progression through G(1) is c-Myc dependent and independent of p27 suppression, Cdk2 activation, or E2F1-dependent transcription |
Q90062681 | Second Generation mTOR Inhibitors as a Double-Edged Sword in Malignant Glioma Treatment |
Q48939509 | Second primary glioblastoma |
Q42370561 | Second-generation HIF-activated oncolytic adenoviruses with improved replication, oncolytic, and antitumor efficacy |
Q39334108 | Silencing of Eps8 blocks migration and invasion in human glioblastoma cell lines |
Q35176325 | Silencing of the tumor suppressor gene WNK2 is associated with upregulation of MMP2 and JNK in gliomas |
Q37269355 | Small-molecule XIAP inhibitors enhance gamma-irradiation-induced apoptosis in glioblastoma |
Q34269290 | Stemness of the CT-2A Immunocompetent Mouse Brain Tumor Model: Characterization In Vitro |
Q30391301 | Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer |
Q28833679 | Structure-activity relationship of 2,2-dimethyl-2H-chromene based arylsulfonamide analogs of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, a novel small molecule hypoxia inducible factor-1 (HIF-1) pathway [...] |
Q26850467 | Sui generis: gene therapy and delivery systems for the treatment of glioblastoma |
Q33989679 | Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors |
Q35683150 | Suppression of G-protein-coupled receptor kinase 3 expression is a feature of classical GBM that is required for maximal growth |
Q34159322 | Synthesis and evaluation of indole-based chalcones as inducers of methuosis, a novel type of nonapoptotic cell death |
Q64244322 | Synthetic Cannabinoids Influence the Invasion of Glioblastoma Cell Lines in a Cell- and Receptor-Dependent Manner |
Q36546689 | TIC10/ONC201 synergizes with Bcl-2/Bcl-xL inhibition in glioblastoma by suppression of Mcl-1 and its binding partners in vitro and in vivo |
Q35756919 | TRAIL and malignant glioma. |
Q92541976 | TRPM7 Induces Mechanistic Target of Rap1b Through the Downregulation of miR-28-5p in Glioma Proliferation and Invasion |
Q36488714 | Targeted cancer gene therapy using a hypoxia inducible factor dependent oncolytic adenovirus armed with interleukin-4 |
Q37041337 | Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression |
Q27652488 | Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases |
Q33780536 | Targeting human glioblastoma cells: comparison of nine viruses with oncolytic potential |
Q39740608 | Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma |
Q38697698 | Temozolomide induces autophagy in primary and established glioblastoma cells in an EGFR independent manner |
Q39214188 | Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in glioblastoma cells |
Q39627791 | The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma |
Q40862061 | The Akt/protein kinase B-dependent anti-apoptotic pathway and the mitogen-activated protein kinase cascade are alternatively activated in human glioblastoma multiforme |
Q34064643 | The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival |
Q61447495 | The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma |
Q35085317 | The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence |
Q40782828 | The development of necrosis and apoptosis in glioma: experimental findings using spheroid culture systems |
Q35105214 | The effect of photoinitiators on intracellular AKT signaling pathway in tissue engineering application |
Q38990450 | The effects of histone deacetylase inhibitors on glioblastoma-derived stem cells. |
Q28391635 | The future role of personalized medicine in the treatment of glioblastoma multiforme |
Q64052634 | The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells |
Q46504176 | The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1alpha (HIF-1alpha ) and inhibits HIF-1-mediated transcription |
Q57162865 | The p53 Pathway in Glioblastoma |
Q35296657 | The polyamine catabolic enzyme SAT1 modulates tumorigenesis and radiation response in GBM |
Q34480697 | The polynuclear platinum BBR3610 induces G2/M arrest and autophagy early and apoptosis late in glioma cells |
Q39820505 | The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair. |
Q48362692 | The tumor suppressor PTEN is exported in exosomes and has phosphatase activity in recipient cells |
Q38742530 | Therapeutic Hypothesis Testing With Rodent Brain Tumor Models. |
Q37137412 | Therapeutic approaches to target cancer stem cells |
Q39691784 | Therapeutic effects of the Sp1 inhibitor mithramycin A in glioblastoma |
Q59134245 | Thioredoxin Confers Intrinsic Resistance to Cytostatic Drugs in Human Glioma Cells |
Q36368481 | Thrombospondin-1 is downregulated by anoxia and suppresses tumorigenicity of human glioblastoma cells |
Q38956529 | Tocotrienol-rich fraction, [6]-gingerol and epigallocatechin gallate inhibit proliferation and induce apoptosis of glioma cancer cells. |
Q61812918 | Transfection with GLS2 Glutaminase (GAB) Sensitizes Human Glioblastoma Cell Lines to Oxidative Stress by a Common Mechanism Involving Suppression of the PI3K/AKT Pathway |
Q50083504 | Tumor Resection Recruits Effector T Cells and Boosts Therapeutic Efficacy of Encapsulated Stem Cells Expressing IFNβ in Glioblastomas. |
Q35000404 | U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells |
Q36782143 | Using a preclinical mouse model of high-grade astrocytoma to optimize p53 restoration therapy. |
Q33112684 | Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism |
Q42974434 | Vorinostat(SAHA) Promotes Hyper-Radiosensitivity in Wild Type p53 Human Glioblastoma Cells. |
Q38899864 | WIF1 re-expression in glioblastoma inhibits migration through attenuation of non-canonical WNT signaling by downregulating the lncRNA MALAT1. |
Q38043443 | What We Know about the Molecular Genetics of Central Nervous System (CNS) Tumours in Malaysia |
Q35751162 | Wilms' tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression |
Q39209883 | ZFX regulates glioma cell proliferation and survival in vitro and in vivo |
Q34423084 | miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas |
Q28307352 | miR-21 and 221 upregulation and miR-181b downregulation in human grade II-IV astrocytic tumors |
Q36048184 | p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells |
Q37522828 | p53 isoform profiling in glioblastoma and injured brain |
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