| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0304-3835(00)00515-2 |
| P698 | PubMed publication ID | 10940516 |
| P2093 | author name string | A Kraus | |
| J Schlegel | |||
| F Neff | |||
| G Piontek | |||
| B Budde | |||
| P2860 | cites work | Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor | Q22009126 |
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| Phosphorylation and regulation of Raf by Akt (protein kinase B) | Q28138863 | ||
| Regulation of cell death protease caspase-9 by phosphorylation | Q28288607 | ||
| Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption | Q28290282 | ||
| Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
| Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo | Q28368373 | ||
| Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 | ||
| How MAP kinases are regulated | Q28609360 | ||
| New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway | Q29616144 | ||
| Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. | Q42824933 | ||
| Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines | Q48154511 | ||
| Amplification of the epidermal-growth-factor-receptor gene correlates with different growth behaviour in human glioblastoma. | Q48191873 | ||
| Expression of alternatively spliced mdm2 transcripts correlates with stabilized wild-type p53 protein in human glioblastoma cells | Q48265209 | ||
| Subsets of glioblastoma multiforme defined by molecular genetic analysis | Q48379049 | ||
| PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis. | Q55476772 | ||
| Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK | Q77387406 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | glioblastoma | Q282142 |
| apoptotic process | Q14599311 | ||
| P304 | page(s) | 103-108 | |
| P577 | publication date | 2000-09-01 | |
| P1433 | published in | Cancer Letters | Q326372 |
| P1476 | title | The Akt/protein kinase B-dependent anti-apoptotic pathway and the mitogen-activated protein kinase cascade are alternatively activated in human glioblastoma multiforme | |
| P478 | volume | 158 |
| Q42115353 | A novel algorithm for detecting differentially regulated paths based on gene set enrichment analysis |
| Q39680687 | Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity |
| Q44215651 | Autocrine signaling through Ras regulates cell survival activity in human glioma cells: potential cross-talk between Ras and the phosphatidylinositol 3-kinase-Akt pathway |
| Q48372076 | Decreased miRNA-637 is an unfavorable prognosis marker and promotes glioma cell growth, migration and invasion via direct targeting Akt1. |
| Q44387794 | Diagnostic and prognostic molecular markers in common adult gliomas |
| Q38735375 | Downregulation of microRNA-637 Increases Risk of Hypoxia-Induced Pulmonary Hypertension by Modulating Expression of Cyclin Dependent Kinase 6 (CDK6) in Pulmonary Smooth Muscle Cells. |
| Q40119822 | Dual targeting of IGF-1R and PDGFR inhibits proliferation in high-grade gliomas cells and induces radiosensitivity in JNK-1 expressing cells. |
| Q40457686 | ERK, PKC and PI3K/Akt pathways mediate extracellular ATP and adenosine-induced proliferation of U138-MG human glioma cell line. |
| Q37246387 | Expression of p-AKT characterizes adenoid cystic carcinomas of head and neck with a higher risk for tumor relapses |
| Q39772800 | Expression of p-Akt and COX-2 in gastric adenocarcinomas and adenovirus mediated Akt1 and COX-2 ShRNA suppresses SGC-7901 gastric adenocarcinoma and U251 glioma cell growth in vitro and in vivo |
| Q44250297 | In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways |
| Q39412061 | Inhibitory effects of ethyl pyruvate administration on human gastric cancer growth via regulation of the HMGB1-RAGE and Akt pathways in vitro and in vivo |
| Q36403136 | Metformin inhibits leptin-induced growth and migration of glioblastoma cells |
| Q39214430 | MicroRNA-149 inhibits proliferation and invasion of glioma cells via blockade of AKT1 signaling |
| Q37286884 | TRAIL-induced apoptosis in gliomas is enhanced by Akt-inhibition and is independent of JNK activation |
| Q38824308 | Therapeutic potential of cyclooxygenase-3 inhibitors in the management of glioblastoma. |
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