scholarly article | Q13442814 |
P50 | author | Eric Guerin | Q56524613 |
Maxime Lehmann | Q39190256 | ||
P2093 | author name string | H Kessler | |
S Martin | |||
M Dontenwill | |||
S Neubauer | |||
G Renner | |||
F Rechenmacher | |||
V Koenig | |||
I Lelong-Rebel | |||
S Bär | |||
A-F Blandin | |||
F Noulet | |||
H Janouskova | |||
J Nuesch | |||
L Choulier | |||
N Etienne-Selloum | |||
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Hallmarks of Cancer: The Next Generation | Q22252312 | ||
Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex | Q24306474 | ||
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1 | Q24651548 | ||
Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action | Q24683017 | ||
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 | Q27642888 | ||
p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer. | Q27851827 | ||
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma | Q27860910 | ||
Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA-15 anti-apoptotic function | Q28215522 | ||
The somatic genomic landscape of glioblastoma | Q28300185 | ||
Activation of p53 by nutlin-3a induces apoptosis and cellular senescence in human glioblastoma multiforme | Q28477660 | ||
Blinded by the Light: The Growing Complexity of p53 | Q29547590 | ||
Integrins in cancer: biological implications and therapeutic opportunities | Q29614536 | ||
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas | Q29616243 | ||
Restoration of p53 function leads to tumour regression in vivo | Q29618727 | ||
Ligand-independent activation of c-Met by fibronectin and α(5)β(1)-integrin regulates ovarian cancer invasion and metastasis | Q30430565 | ||
Improved grading and survival prediction of human astrocytic brain tumors by artificial neural network analysis of gene expression microarray data | Q31153954 | ||
Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors. | Q33209208 | ||
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial | Q33417361 | ||
Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis | Q33438165 | ||
Integrin expression profiling identifies integrin alpha5 and beta1 as prognostic factors in early stage non-small cell lung cancer | Q33955214 | ||
Integrated high-throughput analysis identifies Sp1 as a crucial determinant of p53-mediated apoptosis | Q34038417 | ||
Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin | Q34103283 | ||
Nemo-like kinase is critical for p53 stabilization and function in response to DNA damage | Q34153536 | ||
Ionizing radiations sustain glioblastoma cell dedifferentiation to a stem-like phenotype through survivin: possible involvement in radioresistance | Q34662363 | ||
YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells | Q34795766 | ||
Emerging landscape of oncogenic signatures across human cancers | Q35058708 | ||
RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo | Q35225270 | ||
Expression of phosphoprotein enriched in astrocytes 15 kDa (PEA-15) in astrocytic tumors: a novel approach of correlating malignancy grade and prognosis | Q48206002 | ||
Expression of survivin in astrocytic tumors: correlation with malignant grade and prognosis | Q48394930 | ||
Selective imaging of the angiogenic relevant integrins α5β1 and αvβ3. | Q53092366 | ||
Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apotosis in human malignant glioma cells. | Q54018179 | ||
Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network | Q35807732 | ||
Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoter | Q36235303 | ||
Strategies for therapeutic targeting of the p53 pathway in cancer. | Q36430162 | ||
A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis | Q36678322 | ||
Grail as a molecular determinant for the functions of the tumor suppressor p53 in tumorigenesis | Q36747299 | ||
Survivin promotion of melanoma metastasis requires upregulation of α5 integrin | Q37151634 | ||
Integrins in angiogenesis and lymphangiogenesis | Q37170752 | ||
ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis. | Q37631181 | ||
Targeting survivin in cancer: the cell-signalling perspective | Q37867746 | ||
Integrins as therapeutic targets. | Q38013361 | ||
Integrin α5β1, the Fibronectin Receptor, as a Pertinent Therapeutic Target in Solid Tumors. | Q38161726 | ||
Survivin as a preferential target for cancer therapy | Q38188377 | ||
Drugging the p53 pathway: understanding the route to clinical efficacy | Q38191796 | ||
Focal adhesion signaling and therapy resistance in cancer | Q38239375 | ||
The extracellular matrix modulates the hallmarks of cancer | Q38266276 | ||
Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity. | Q38315813 | ||
E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis | Q38963822 | ||
Single cell tracking assay reveals an opposite effect of selective small non-peptidic α5β1 or αvβ3/β5 integrin antagonists in U87MG glioma cells. | Q38996999 | ||
Radiation-induced mitotic cell death and glioblastoma radioresistance: a new regulating pathway controlled by integrin-linked kinase, hypoxia-inducible factor 1 alpha and survivin in U87 cells | Q39142533 | ||
β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments | Q39147447 | ||
Activation of p53 pathway by Nutlin-3a inhibits the expression of the therapeutic target α5 integrin in colon cancer cells | Q39176861 | ||
The PEA-15/PED protein regulates cellular survival and invasiveness in colorectal carcinomas | Q39182293 | ||
Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma. | Q39347057 | ||
Chk2 mediates RITA-induced apoptosis | Q39430270 | ||
Survivin Enhances Motility of Melanoma Cells by Supporting Akt Activation and α5 Integrin Upregulation | Q39661250 | ||
alpha5beta1 integrin antagonists reduce chemotherapy-induced premature senescence and facilitate apoptosis in human glioblastoma cells | Q39748375 | ||
The PEA-15/PED protein protects glioblastoma cells from glucose deprivation-induced apoptosis via the ERK/MAP kinase pathway. | Q40093567 | ||
ECM overrides DNA damage-induced cell cycle arrest and apoptosis in small-cell lung cancer cells through beta1 integrin-dependent activation of PI3-kinase | Q40330305 | ||
PED mediates AKT-dependent chemoresistance in human breast cancer cells | Q40390454 | ||
FLICE/caspase-8 activation triggers anoikis induced by beta1-integrin blockade in human keratinocytes. | Q40499562 | ||
Fibronectin Protects Prostate Cancer Cells from Tumor Necrosis Factor-α-induced Apoptosis via the AKT/Survivin Pathway | Q40629411 | ||
A monoclonal antibody inhibits adhesion to fibronectin and vitronectin of a colon carcinoma cell line and recognizes the integrins alpha v beta 3, alpha v beta 5, and alpha v beta 6. | Q41474344 | ||
Microarray analysis verifies two distinct phenotypes of glioblastomas resistant to antiangiogenic therapy | Q41809732 | ||
Differentiation therapy exerts antitumor effects on stem-like glioma cells | Q42814006 | ||
PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation | Q44594112 | ||
Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction | Q46853183 | ||
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines | Q48154511 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 4 | |
P921 | main subject | apoptotic process | Q14599311 |
P304 | page(s) | 640-653 | |
P577 | publication date | 2015-10-16 | |
P1433 | published in | Cell Death & Differentiation | Q2943974 |
P1476 | title | Integrin α5β1 and p53 convergent pathways in the control of anti-apoptotic proteins PEA-15 and survivin in high-grade glioma | |
P478 | volume | 23 |
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