Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity

scientific article published on 20 January 2020

Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-020-57506-9
P932PMC publication ID6971268
P698PubMed publication ID31959836

P50authorDavide M FerrarisQ58976256
Anna WilkQ92783219
Menico RizziQ28322663
Robert W SobolQ57006611
P2093author name stringPeter Sykora
Jennifer Clark
Jianfeng Li
Amanda Davis
Joel Andrews
Laurent Chaloin
Faisal Hayat
Richard Cunningham
Silvia Garavaglia
Leila Zamani
Marie Migaud
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Is a NAD pyrophosphatase activity necessary for Haemophilus influenzae type b multiplication in the blood stream?Q34091051
Spatial and temporal cellular responses to single-strand breaks in human cells.Q34197035
ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion.Q34254806
Alkylation sensitivity screens reveal a conserved cross-species functionomeQ34434871
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HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase βQ34581562
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The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 functionQ35679372
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Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells.Q36282881
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Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse modelsQ36784219
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Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-JoiningQ37445974
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A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP5.Q47816989
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Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell linesQ48154511
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NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA RepairQ49273526
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NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiencyQ50063845
Nicotine Adenine Dinucleotides: The Redox Currency of the CellQ50119164
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PARP inhibitor rucaparib induces changes in NAD levels in cells and liver tissues as assessed by MRS.Q50980480
Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA.Q52316501
Quantitative Analysis of NAD Synthesis-Breakdown Fluxes.Q52568842
Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk.Q53156661
NADH-linked metabolic plasticity of MCF-7 breast cancer cells surviving in a nutrient-deprived microenvironment.Q54300735
Alkaline Comet Assay for Assessing DNA Damage in Individual Cells.Q55059233
The Plasma NAD Metabolome Is Dysregulated in "Normal" AgingQ57799627
CD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD PoolsQ58197337
P4510describes a project that usesaffyQ113334509
P433issue1
P304page(s)651
P577publication date2020-01-20
P1433published inScientific ReportsQ2261792
P1476titleExtracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity
P478volume10

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