scholarly article | Q13442814 |
P50 | author | Davide M Ferraris | Q58976256 |
Anna Wilk | Q92783219 | ||
Menico Rizzi | Q28322663 | ||
Robert W Sobol | Q57006611 | ||
P2093 | author name string | Peter Sykora | |
Jennifer Clark | |||
Jianfeng Li | |||
Amanda Davis | |||
Joel Andrews | |||
Laurent Chaloin | |||
Faisal Hayat | |||
Richard Cunningham | |||
Silvia Garavaglia | |||
Leila Zamani | |||
Marie Migaud | |||
P2860 | cites work | Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes | Q59798260 |
Microvesicles released from multiple myeloma cells are equipped with ectoenzymes belonging to canonical and non-canonical adenosinergic pathways and produce adenosine from ATP and NAD | Q61398598 | ||
Extension of human cell lifespan by nicotinamide phosphoribosyltransferase | Q64377238 | ||
SnapShot: ADP-Ribosylation Signaling | Q89385353 | ||
The Regulatory Role of NAD in Human and Animal Cells | Q91364666 | ||
Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts | Q91676965 | ||
Slc12a8 is a nicotinamide mononucleotide transporter | Q92309613 | ||
Dihydronicotinamide riboside is a potent NAD+ concentration enhancer in vitro and in vivo | Q92859473 | ||
XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage | Q24522502 | ||
Emerging functions of extracellular pyridine nucleotides | Q24677526 | ||
ARTD1 (PARP1) activation and NAD(+) in DNA repair and cell death | Q27027461 | ||
Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss | Q27318173 | ||
A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome | Q27318209 | ||
Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities | Q27638068 | ||
The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism | Q27674322 | ||
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans | Q27937147 | ||
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data | Q28266682 | ||
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal | Q28288215 | ||
Genome-scale CRISPR-Cas9 knockout screening in human cells | Q29616044 | ||
Connexin 43 hemi channels mediate Ca2+-regulated transmembrane NAD+ fluxes in intact cells | Q31636101 | ||
The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor | Q33376941 | ||
Safety and efficacy of NAD depleting cancer drugs: results of a phase I clinical trial of CHS 828 and overview of published data | Q33386435 | ||
CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppression | Q33533705 | ||
Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage | Q33598840 | ||
NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells | Q33813414 | ||
NADP and NAD utilization in Haemophilus influenzae | Q33897718 | ||
NadN and e (P4) are essential for utilization of NAD and nicotinamide mononucleotide but not nicotinamide riboside in Haemophilus influenzae | Q33950279 | ||
NAD+ and sirtuins in aging and disease | Q33955066 | ||
NAD+ metabolism in health and disease | Q34001412 | ||
NAD+ and vitamin B3: from metabolism to therapies | Q34009126 | ||
Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition | Q34011250 | ||
Role of nicotinamide in DNA damage, mutagenesis, and DNA repair | Q34042309 | ||
Is a NAD pyrophosphatase activity necessary for Haemophilus influenzae type b multiplication in the blood stream? | Q34091051 | ||
Spatial and temporal cellular responses to single-strand breaks in human cells. | Q34197035 | ||
ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion. | Q34254806 | ||
Alkylation sensitivity screens reveal a conserved cross-species functionome | Q34434871 | ||
The multifaceted functions of sirtuins in cancer | Q34494682 | ||
NAD⁺ in aging, metabolism, and neurodegeneration. | Q34509810 | ||
Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. | Q34539655 | ||
HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β | Q34581562 | ||
Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair | Q34802264 | ||
Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage | Q34987124 | ||
Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction. | Q35165995 | ||
Improved vectors and genome-wide libraries for CRISPR screening | Q35215629 | ||
Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice | Q35486021 | ||
The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function | Q35679372 | ||
Micro-irradiation tools to visualize base excision repair and single-strand break repair | Q35690306 | ||
Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells. | Q36282881 | ||
A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification | Q36751371 | ||
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model | Q36771997 | ||
Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models | Q36784219 | ||
Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes | Q36913813 | ||
The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases. | Q36992615 | ||
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells | Q37151029 | ||
Nampt: linking NAD biology, metabolism and cancer | Q37334248 | ||
The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors | Q37410764 | ||
Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-Joining | Q37445974 | ||
An NAD+-dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma | Q37534085 | ||
CD73: a potent suppressor of antitumor immune responses | Q38001161 | ||
Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors | Q38107280 | ||
Targeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer | Q38209586 | ||
Nuclear ADP-Ribosylation and Its Role in Chromatin Plasticity, Cell Differentiation, and Epigenetics. | Q38369403 | ||
The human NAD metabolome: Functions, metabolism and compartmentalization | Q38402636 | ||
Physiological and pathophysiological roles of NAMPT and NAD metabolism | Q38555243 | ||
The comet assay: Reflections on its development, evolution and applications | Q38560270 | ||
NAMPT as a Therapeutic Target against Stroke. | Q38625625 | ||
Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin | Q38726326 | ||
CD73 on B16F10 melanoma cells in CD73-deficient mice promotes tumor growth, angiogenesis, neovascularization, macrophage infiltration and metastasis | Q38821474 | ||
CD73 is associated with poor prognosis in high-grade serous ovarian cancer | Q38835904 | ||
PARP, transcription and chromatin modeling | Q38966063 | ||
NAD+ salvage pathway in cancer metabolism and therapy | Q38999807 | ||
The multifaceted roles of PARP1 in DNA repair and chromatin remodelling. | Q39414183 | ||
NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink | Q39968449 | ||
T98G: An anchorage-independent human tumor cell line that exhibits stationary phase G1 arrest in vitro | Q40238875 | ||
Role of estrogen receptor in the regulation of ecto-5'-nucleotidase and adenosine in breast cancer | Q40593419 | ||
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis | Q40617327 | ||
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. | Q41068775 | ||
PTEN suppresses hyaluronic acid-induced matrix metalloproteinase-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphorylation. | Q42527541 | ||
A self-restricted CD38-connexin 43 cross-talk affects NAD+ and cyclic ADP-ribose metabolism and regulates intracellular calcium in 3T3 fibroblasts | Q42824644 | ||
Nicotinamide phosphoribosyltransferase (NAMPT) is over-expressed in melanoma lesions | Q44293088 | ||
Antiangiogenic potency of FK866/K22.175, a new inhibitor of intracellular NAD biosynthesis, in murine renal cell carcinoma. | Q44775393 | ||
Plasma purine nucleoside phosphorylase in cancer patients | Q44900944 | ||
NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. | Q45193551 | ||
Lipid rafts remodeling in estrogen receptor-negative breast cancer is reversed by histone deacetylase inhibitor | Q46966360 | ||
Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development | Q47285805 | ||
Regulation of cancer and cancer-related genes via NAD. | Q47731726 | ||
Application of Laser Micro-irradiation for Examination of Single and Double Strand Break Repair in Mammalian Cells | Q47772207 | ||
A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP5. | Q47816989 | ||
Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface. | Q48150041 | ||
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines | Q48154511 | ||
Extracellular nucleosides and nucleotides as immunomodulators | Q48193659 | ||
NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair | Q49273526 | ||
Next generation high throughput DNA damage detection platform for genotoxic compound screening. | Q49394134 | ||
NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency | Q50063845 | ||
Nicotine Adenine Dinucleotides: The Redox Currency of the Cell | Q50119164 | ||
Regulatory Effects of NAD+ Metabolic Pathways on Sirtuin Activity | Q50139416 | ||
PARP inhibitor rucaparib induces changes in NAD levels in cells and liver tissues as assessed by MRS. | Q50980480 | ||
Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA. | Q52316501 | ||
Quantitative Analysis of NAD Synthesis-Breakdown Fluxes. | Q52568842 | ||
Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk. | Q53156661 | ||
NADH-linked metabolic plasticity of MCF-7 breast cancer cells surviving in a nutrient-deprived microenvironment. | Q54300735 | ||
Alkaline Comet Assay for Assessing DNA Damage in Individual Cells. | Q55059233 | ||
The Plasma NAD Metabolome Is Dysregulated in "Normal" Aging | Q57799627 | ||
CD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD Pools | Q58197337 | ||
P4510 | describes a project that uses | affy | Q113334509 |
P433 | issue | 1 | |
P304 | page(s) | 651 | |
P577 | publication date | 2020-01-20 | |
P1433 | published in | Scientific Reports | Q2261792 |
P1476 | title | Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity | |
P478 | volume | 10 |
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