Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent

scientific article published on 27 January 2010

Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NEUONC/NOP048
P932PMC publication ID2940627
P698PubMed publication ID20406898
P5875ResearchGate publication ID43226833

P50authorKevin A. RothQ42407889
P2093author name stringLatika Kohli
Barbara J Klocke
Ying Geng
P2860cites workDNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cellsQ40237176
Acridine derivatives activate p53 and induce tumor cell death through Bax.Q40370167
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cellsQ40600919
Molecular response of human glioblastoma multiforme cells to ionizing radiation: cell cycle arrest, modulation of the expression of cyclin-dependent kinase inhibitors, and autophagyQ40604670
Mefloquine in the treatment and prevention of malariaQ40844409
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.Q41915692
Intragastric mefloquine is absorbed rapidly in patients with cerebral malariaQ41916529
Chloroquine-induced neuronal cell death is p53 and Bcl-2 family-dependent but caspase-independentQ41918709
Status of oxidative stress and antioxidant defences during Plasmodivm knowlesi infection and chloroquine treatment in Macaca mulattaQ41940372
Chloroquine mediates specific proteome oxidative damage across the erythrocytic cycle of resistant Plasmodium falciparumQ41941122
Antimalarial activity of optical isomers of quinacrine dihydrochloride against chloroquine-sensitive and -resistant plasmodium falciparum in vitroQ41941146
Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neuronsQ41946151
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell linesQ48154511
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanineQ48479768
Effects of lysosomotropic monoamines, diamines, amino alcohols, and other amino compounds on protein degradation and protein synthesis in isolated rat hepatocytesQ71488515
Inhibition of macroautophagy triggers apoptosisQ24338482
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processingQ24597817
Growth factor regulation of autophagy and cell survival in the absence of apoptosisQ28588809
Induction of a Common Pathway of Apoptosis by StaurosporineQ29042381
Self-eating and self-killing: crosstalk between autophagy and apoptosisQ29617748
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphomaQ29622918
Pathological and clinical features of cystic and noncystic glioblastomasQ31140613
A novel response of cancer cells to radiation involves autophagy and formation of acidic vesiclesQ32046208
Therapy of glioblastoma multiforme improved by the antimutagenic chloroquineQ33985231
Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trialQ33993957
Pathways of apoptotic and non-apoptotic death in tumour cellsQ35852309
Glioblastoma multiforme: the terminatorQ36101892
Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophagesQ36205312
The role of autophagy in cancer development and response to therapy.Q36251939
Lysosomes and autophagy in cell death controlQ36292872
Mefloquine-induced disruption of calcium homeostasis in mammalian cells is similar to that induced by ionomycinQ36424992
Elimination of wild-type P53 mRNA in glioblastomas showing heterozygous mutations of P53.Q36615676
Proautophagic drugs: a novel means to combat apoptosis-resistant cancers, with a special emphasis on glioblastomasQ37047723
Chloroquine-induced nitric oxide increase and cell death is dependent on cellular GSH depletion in A172 human glioblastoma cellsQ39999573
Survival of patients with glioblastoma multiforme has not improved between 1993 and 2004: analysis of 625 cases.Q40174718
P433issue5
P921main subjectcell deathQ2383867
vacuoleQ127702
autophagyQ288322
chloroquineQ422438
P304page(s)473-481
P577publication date2010-01-27
P1433published inNeuro-OncologyQ15724471
P1476titleChloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent
P478volume12