DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells

scientific article published on September 2006

DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1005415207
P356DOI10.1038/SJ.CDD.4402030
P698PubMed publication ID16946731
P5875ResearchGate publication ID6842008

P2093author name stringT Kawaguchi
M S Berger
M Katayama
R O Pieper
P2860cites workRole of autophagy in temozolomide-induced cytotoxicity for malignant glioma cellsQ40600919
Inhibition of DNA repair for sensitizing resistant glioma cells to temozolomideQ40602396
A signaling pathway to translational controlQ41073792
Hormonal stimulation of mitochondrial pyruvate carboxylation in filipin-treated hepatocytesQ42864247
Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchangeQ74607067
Autophagy: molecular machinery for self-eatingQ24678361
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastomaQ27860910
Cell death by mitotic catastrophe: a molecular definitionQ28255830
Upstream and downstream of mTORQ28277365
Classification of cell death: recommendations of the Nomenclature Committee on Cell DeathQ28278883
Growth factor regulation of autophagy and cell survival in the absence of apoptosisQ28588809
Autophagy in cell death: an innocent convict?Q29617604
Autophagy in health and disease: a double-edged swordQ29618103
Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8Q29620200
Another way to die: autophagic programmed cell deathQ34462605
If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cellsQ34625589
Diversity of signaling controls of macroautophagy in mammalian cells.Q35063328
Autophagy: a barrier or an adaptive response to cancer.Q35078446
Autophagy in metazoans: cell survival in the land of plentyQ36146937
Restarting the cell cycle when the checkpoint comes to a haltQ36231461
The role of autophagy in cancer development and response to therapy.Q36251939
Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagyQ40250473
Akt activation suppresses Chk2-mediated, methylating agent-induced G2 arrest and protects from temozolomide-induced mitotic catastrophe and cellular senescenceQ40414464
P433issue3
P921main subjectadenosine triphosphateQ80863
autophagyQ288322
P304page(s)548-558
P577publication date2006-09-01
P1433published inCell Death & DifferentiationQ2943974
P1476titleDNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells
P478volume14

Reverse relations

cites work (P2860)
Q56774085A novel cell type-specific role of p38α in the control of autophagy and cell death in colorectal cancer cells
Q33416266A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
Q89742633A risk signature with four autophagy-related genes for predicting survival of glioblastoma multiforme
Q28488211ABT-263 enhances sensitivity to metformin and 2-deoxyglucose in pediatric glioma by promoting apoptotic cell death
Q39545841AMPK-mediated autophagy is a survival mechanism in androgen-dependent prostate cancer cells subjected to androgen deprivation and hypoxia
Q86425843ATG9A overexpression is associated with disease recurrence and poor survival in patients with oral squamous cell carcinoma
Q36907054ATM-NFκB axis-driven TIGAR regulates sensitivity of glioma cells to radiomimetics in the presence of TNFα.
Q37578687Acanthopanax versus 3-Methyladenine Ameliorates Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting the Autophagic Pathway in Rats.
Q37141408Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy
Q42802552An executioner caspase regulates autophagy
Q62636307Antitumor Monoterpenes
Q37605156Apoptosis and autophagy: Regulation of apoptosis by DNA damage signalling - roles of p53, p73 and HIPK2.
Q57245707At the core of survival: Autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury
Q29614564Autophagic cell death: the story of a misnomer
Q39665408Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis
Q58804966Autophagic flux response and glioblastoma sensitivity to radiation
Q34384256Autophagy activity in pulmonary metastatic tumor tissues from colorectal cancer: a pilot study
Q42571763Autophagy and apoptosis: what is the connection?
Q82997243Autophagy and cancer therapy
Q38128164Autophagy and genomic integrity.
Q38462513Autophagy and its function in radiosensitivity
Q37768714Autophagy and tumorigenesis
Q35557084Autophagy as a modulator and target in prostate cancer
Q37876679Autophagy as a target for anticancer therapy
Q38820678Autophagy contributes to the chemo-resistance of non-small cell lung cancer in hypoxic conditions
Q27346475Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab
Q39412865Autophagy in Cancer Therapy
Q38334146Autophagy in DNA damage response
Q38134372Autophagy in blood cancers: biological role and therapeutic implications.
Q35624780Autophagy in brain tumors: a new target for therapeutic intervention
Q36611434Autophagy in toxicology: self-consumption in times of stress and plenty
Q37533134Autophagy in tumour suppression and promotion
Q36739017Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells
Q38034270Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity
Q34373067Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells
Q92603216Autophagy role(s) in response to oncogenes and DNA replication stress
Q36972773Autophagy-induced tumor dormancy in ovarian cancer
Q36715331Beclin1 inhibition promotes autophagy and decreases gemcitabine-induced apoptosis in Miapaca2 pancreatic cancer cells
Q38026774Blastic leukaemias (AML): a biologist's view
Q34515135Cathepsin B facilitates autophagy-mediated apoptosis in SPARC overexpressed primitive neuroectodermal tumor cells
Q38331755Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy
Q35521316Chemoresistance of glioblastoma cancer stem cells--much more complex than expected
Q37799220Chemotherapy and signaling: How can targeted therapies supercharge cytotoxic agents?
Q26827797Chloroquine and hydroxychloroquine for cancer therapy
Q65556504Chloroquine and nanoparticle drug delivery: A promising combination
Q41919095Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells
Q30513775Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy
Q39712685Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent
Q34096767Combination of AKT inhibition with autophagy blockade effectively reduces ascites-derived ovarian cancer cell viability
Q36982114Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model
Q45332658Concomitant treatment with pertussis toxin plus temozolomide increases the survival of rats bearing intracerebral RG2 glioma.
Q39555301Considering temozolomide as a novel potential treatment for esophageal cancer
Q39375263Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis.
Q34163076Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma.
Q35017721DNA damage and autophagy
Q37505517DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment
Q24311383DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription
Q26825417DangER: protein ovERload. Targeting protein degradation to treat myeloma
Q33621745Deoxycholate, an endogenous cytotoxin/genotoxin, induces the autophagic stress-survival pathway: implications for colon carcinogenesis
Q36189324Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents
Q34517339Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas
Q28473257Disruption of neuronal autophagy by infected microglia results in neurodegeneration
Q39321309EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells
Q91741531Ecliptasaponin A induces apoptosis through the activation of ASK1/JNK pathway and autophagy in human lung cancer cells
Q34677497Effect of autophagy inhibition on chemotherapy-induced apoptosis in A549 lung cancer cells
Q39305165Effect of temozolomide on the U-118 glioma cell line
Q55456917Effects of sequentially applied single and combined temozolomide, hydroxychloroquine and AT101 treatment in a long-term stimulation glioblastoma in vitro model.
Q37466859Equine metabolic syndrome impairs adipose stem cells osteogenic differentiation by predominance of autophagy over selective mitophagy
Q39758383Expression of Beclin1 in osteosarcoma and the effects of down-regulation of autophagy on the chemotherapeutic sensitivity
Q33794114HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains
Q36645695High levels of cellular proliferation predict pseudoprogression in glioblastoma patients
Q97543212Hydroxychloroquine and short-course radiotherapy in elderly patients with newly diagnosed high-grade glioma: a randomized phase II trial
Q37680934Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens
Q42541156Implications of therapy-induced selective autophagy on tumor metabolism and survival
Q36810992Inhibition of BMI1 induces autophagy-mediated necroptosis
Q37054380Inhibition of JNK-mediated autophagy enhances NSCLC cell sensitivity to mTORC1/2 inhibitors
Q34606255Inhibition of autophagosome formation by the benzoporphyrin derivative verteporfin
Q39757793Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells
Q58799521Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis
Q39124155Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells
Q92212328Inhibition of autophagy triggers melatonin-induced apoptosis in glioblastoma cells
Q39839523Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells
Q28482453Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion
Q89604972Introduction to Purinergic Signalling in the Brain
Q39114980Involvement of autophagy in recombinant human arginase-induced cell apoptosis and growth inhibition of malignant melanoma cells.
Q30500762JLK1486, a Bis 8-Hydroxyquinoline-Substituted Benzylamine, Displays Cytostatic Effects in Experimental Gliomas through MyT1 and STAT1 Activation and, to a Lesser Extent, PPARγ Activation
Q38009194Killing a cancer: what are the alternatives?
Q35743276LC3B globular structures correlate with survival in esophageal adenocarcinoma
Q48503758Lhx8 ablation leads to massive autophagy of mouse oocytes associated with DNA damage.
Q34141265Long-term cisplatin exposure impairs autophagy and causes cisplatin resistance in human lung cancer cells
Q34105361Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression
Q33588294Long-term temozolomide treatment induces marked amino metabolism modifications and an increase in TMZ sensitivity in Hs683 oligodendroglioma cells
Q36808390MIR517C inhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocation
Q41910277Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma
Q38833604Mechanisms of autophagy and apoptosis: Recent developments in breast cancer cells
Q37731350Methods for detecting autophagy and determining autophagy-induced cell death.
Q48137821Molecular events leading to death of Leishmania donovani under spermidine starvation after hypericin treatment
Q37719938Molecular mechanisms of chemoresistance in osteosarcoma (Review).
Q26776299Molecular mechanisms of etoposide
Q28541848Multiplexing spheroid volume, resazurin and acid phosphatase viability assays for high-throughput screening of tumour spheroids and stem cell neurospheres
Q64971718NEO212 induces mitochondrial apoptosis and impairs autophagy flux in ovarian cancer.
Q47106854Natural agents mediated autophagic signal networks in cancer
Q39849848Oxidative stress induces parallel autophagy and mitochondria dysfunction in human glioma U251 cells
Q64054819PDIA6 modulates apoptosis and autophagy of non-small cell lung cancer cells via the MAP4K1/JNK signaling pathway
Q34372972Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma
Q26853192Photoreceptor cell death and rescue in retinal detachment and degenerations
Q34787732Principles and current strategies for targeting autophagy for cancer treatment
Q44630263Probing the key interactions between human Atg5 and Atg16 proteins: a prospective application of molecular modeling
Q37466253Programmed cell death pathways and current antitumor targets
Q41946240Protein kinase C β inhibits autophagy and sensitizes cervical cancer Hela cells to cisplatin
Q36781485Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis, and poor outcome
Q24618782Purinergic signalling and cancer
Q34373116Reciprocal regulation of autophagy and dNTP pools in human cancer cells
Q38148991Regulation and function of mitophagy in development and cancer.
Q52599334Regulation of Autophagy Affects the Prognosis of Mice with Severe Acute Pancreatitis.
Q44760238Regulation of autophagy and ubiquitinated protein accumulation by bFGF promotes functional recovery and neural protection in a rat model of spinal cord injury
Q30540223Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells.
Q37148255Retinoblastoma protein regulates the crosstalk between autophagy and apoptosis, and favors glioblastoma resistance to etoposide.
Q35161917Role and regulation of autophagy in cancer
Q36149227Role of autophagy and lysosomal drug sequestration in acquired resistance to doxorubicin in MCF-7 cells
Q29617748Self-eating and self-killing: crosstalk between autophagy and apoptosis
Q37628979Simultaneous activation and inhibition of autophagy sensitizes cancer cells to chemotherapy
Q38907601Single-cell analysis challenges the connection between autophagy and senescence induced by DNA damage
Q34660074Small-molecule regulators of autophagy and their potential therapeutic applications
Q35591586Spectral imaging-based methods for quantifying autophagy and apoptosis.
Q42365063Study on the Mechanism of mTOR-Mediated Autophagy during Electroacupuncture Pretreatment against Cerebral Ischemic Injury.
Q39048858Suppression of autophagy enhances preferential toxicity of paclitaxel to folliculin-deficient renal cancer cells
Q39957310Suppression of autophagy enhances the cytotoxicity of the DNA-damaging aromatic amine p-anilinoaniline
Q33727550Synergistic killing of lung cancer cells by cisplatin and radiation via autophagy and apoptosis
Q41345579TDP-43/HDAC6 axis promoted tumor progression and regulated nutrient deprivation-induced autophagy in glioblastoma
Q35852757TXNDC17 promotes paclitaxel resistance via inducing autophagy in ovarian cancer
Q88406511Targeting autophagy in cancer
Q26782468Targeting autophagy in cancer management - strategies and developments
Q37707832Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer
Q34754083Temozolomide modifies caveolin-1 expression in experimental malignant gliomas in vitro and in vivo
Q57812376The Novel Autophagy Inhibitor Alpha-Hederin Promoted Paclitaxel Cytotoxicity by Increasing Reactive Oxygen Species Accumulation in Non-Small Cell Lung Cancer Cells
Q54968392The Role of Autophagy and the Chemokine (C-X-C Motif) Ligand 16 During Acute Lung Injury in Mice.
Q37514559The activation of c-Jun NH₂-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells
Q45924302The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells.
Q39907475The chemotherapeutic agents XK469 (2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid) and SH80 (2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid) inhibit cytokinesis and promote polyploidy and induce senescence
Q38488109The interplay between DNA repair and autophagy in cancer therapy
Q37924056The role of autophagy in cancer: therapeutic implications
Q26764947Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve
Q28536969Thymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cells
Q38747197Trivalent Chromium Induces Autophagy by Activating Sphingomyelin Phosphodiesterase 2 and Increasing Cellular Ceramide Levels in Renal HK2 Cells.
Q35751162Wilms' tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression
Q35626306microRNA-101 is a potent inhibitor of autophagy

Search more.