Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome

scientific article published on 14 July 2005

Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2005-05-1980
P932PMC publication ID1895045
P698PubMed publication ID16020503

P50authorCharles A. DinarelloQ834442
Pascale PaulQ56909742
Daniela NovickQ77912071
P2093author name stringMenachem Rubinstein
Nicolas Schleinitz
Pascale Paul
Catherine Farnarier
Gilles Kaplanski
Valérie Marin
Stéphane Robitail
Véronique Veit
Karin Mazodier
Jean-Robert Harlé
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IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cellsQ30304035
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Interleukin-18 regulates both Th1 and Th2 responsesQ34178165
The role of cytotoxicity in lymphocyte homeostasis.Q34360492
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Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cellsQ37179132
Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cellsQ37378111
IL-18 up-regulates perforin-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL-18 receptor.Q38328380
Virus-associated hemophagocytic syndromeA benign histiocytic proliferation distinct from malignant histiocytosisQ40251317
An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorderQ40536555
Oversecretion of IL-18 in haemophagocytic lymphohistiocytosis: a novel marker of disease activityQ40634625
Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndromeQ40663505
Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemiaQ40734859
Hypercytokinemia in familial hemophagocytic lymphohistiocytosisQ40741786
Levels of interleukin-18 and its binding inhibitors in the blood circulation of patients with adult-onset Still's diseaseQ40819082
Bacteria-associated hemophagocytic syndromeQ40822509
The class I MHC homologue of human cytomegalovirus inhibits attack by natural killer cellsQ41116878
Differential diagnosis of hemophagocytic syndrome: underlying disorders and selection of the most effective treatmentQ41581320
Familial hemophagocytic lymphohistiocytosis. Primary hemophagocytic lymphohistiocytosisQ41751139
Infection- and malignancy-associated hemophagocytic syndromes. Secondary hemophagocytic lymphohistiocytosisQ41751145
A novel role for interleukin-18 in human natural killer cell death: high serum levels and low natural killer cell numbers in patients with systemic autoimmune diseasesQ43584281
A novel IL-18BP ELISA shows elevated serum IL-18BP in sepsis and extensive decrease of free IL-18.Q43702638
Increased interleukin-18 expression in bone marrow of a patient with systemic juvenile idiopathic arthritis and unrecognized macrophage-activation syndromeQ47368371
Neutralizing antibodies to IFN-gamma-inducing factor prevent experimental autoimmune encephalomyelitisQ48339467
Macrophage activation syndrome.Q53961099
Elevated soluble interleukin-2 receptor in childhood hemophagocytic histiocytic syndromes.Q55242245
Calculation of lytic units for the expression of cell-mediated cytotoxicityQ67744337
Diagnostic guidelines for hemophagocytic lymphohistiocytosis. The FHL Study Group of the Histiocyte SocietyQ68192027
Impaired natural killer activity in lymphohistiocytosis syndromeQ70333237
Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosisQ73374152
Adult onset Still's disease associated hemophagocytosisQ73601289
Serum IL-18 levels in patients with various hematological disordersQ73859346
IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 familyQ77807763
Proposal for a new set of classification criteria for adult-onset still diseaseQ78069999
Hemophagocytic lymphohistiocytosis is associated with deficiencies of cellular cytolysis but normal expression of transcripts relevant to killer-cell-induced apoptosisQ78290400
Highly elevated serum levels of interleukin-18 in systemic juvenile idiopathic arthritis but not in other juvenile idiopathic arthritis subtypes or in Kawasaki disease: comment on the article by Kawashima et alQ78301243
Histiocyte disordersQ80120439
P433issue10
P407language of work or nameEnglishQ1860
P1104number of pages7
P304page(s)3483-3489
P577publication date2005-07-14
P1433published inBloodQ885070
P1476titleSevere imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome
P478volume106

Reverse relations

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