Paeonol Protects Memory after Ischemic Stroke via Inhibiting β-Secretase and Apoptosis

scientific article published on 13 March 2012

Paeonol Protects Memory after Ischemic Stroke via Inhibiting β-Secretase and Apoptosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1155/2012/932823
P932PMC publication ID3312264
P698PubMed publication ID22474531
P5875ResearchGate publication ID223986986

P2093author name stringTung-Hu Tsai
Ching-Liang Hsieh
Chin-Yi Cheng
Shan-Yu Su
P2860cites workApoptosis: controlled demolition at the cellular levelQ29620114
The beta-secretase, BACE: a prime drug target for Alzheimer's diseaseQ32061148
Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factorsQ33814389
Secretases as targets for the treatment of Alzheimer's diseaseQ34046308
Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's diseaseQ34168739
Paeonol reduced cerebral infarction involving the superoxide anion and microglia activation in ischemia-reperfusion injured ratsQ34491407
Apoptosis and brain ischaemiaQ35092250
Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of β-secretase (BACE1)Q35642456
Neuronal death/survival signaling pathways in cerebral ischemiaQ36045204
From brain ischemia-reperfusion injury to possible sporadic Alzheimer's diseaseQ36266186
The inflammatory response in strokeQ36692346
Caspase-independent programmed cell death following ischemic strokeQ37196722
Natural antioxidants protect neurons in Alzheimer's disease and Parkinson's diseaseQ37363138
Apoptotic mechanisms after cerebral ischemiaQ37381350
Alzheimer's mechanisms in ischemic brain degenerationQ37640009
Amyloid-β production: major link between oxidative stress and BACE1.Q37946306
Roles of amyloid precursor protein family members in neuroprotection, stress signaling and agingQ37956562
Isatis indigotica induces hepatocellular cancer cell death via caspase-independent apoptosis-inducing factor translocation apoptotic pathway in vitro and in vivo.Q39580008
Paeonol attenuates H₂O₂-induced NF-κB-associated amyloid precursor protein expressionQ39634166
Morin inhibits 12-O-tetradecanoylphorbol-13-acetate-induced hepatocellular transformation via activator protein 1 signaling pathway and cell cycle progressionQ40421974
Polyphyllin D is a potent apoptosis inducer in drug-resistant HepG2 cells.Q40477426
Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase.Q40621475
Inhibition of apoptosis by hyperbaric oxygen in a rat focal cerebral ischemic model.Q42171702
Expression of human beta-secretase in the mouse brain increases the steady-state level of beta-amyloid.Q43955854
The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosisQ44581792
Increased beta-secretase activity and expression in rats following transient cerebral ischemiaQ44878523
Focal cerebral ischemia in rats alters APP processing and expression of Abeta peptide degrading enzymes in the thalamus.Q46019760
Ferulic acid reduces cerebral infarct through its antioxidative and anti-inflammatory effects following transient focal cerebral ischemia in ratsQ46217889
Vascular risk factors, incidence of MCI, and rates of progression to dementiaQ46236546
Paeonol attenuates neurotoxicity and ameliorates cognitive impairment induced by d-galactose in ICR miceQ46247684
Neuroprotective effects of berberine on stroke models in vitro and in vivoQ46329583
Transformation of diffuse beta-amyloid precursor protein and beta-amyloid deposits to plaques in the thalamus after transient occlusion of the middle cerebral artery in ratsQ46525415
Anxiolytic-like effect of paeonol in miceQ46560149
Ferulic acid provides neuroprotection against oxidative stress-related apoptosis after cerebral ischemia/reperfusion injury by inhibiting ICAM-1 mRNA expression in ratsQ46654615
Paeonol prevents excitotoxicity in rat pheochromocytoma PC12 cells via downregulation of ERK activation and inhibition of apoptosisQ46741364
Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences.Q48275623
Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia.Q48397448
Astroglial expression of the beta-amyloid in ischemia-reperfusion brain injuryQ48426714
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.Q48455875
A Bax-induced pro-oxidant state is critical for cytochrome c release during programmed neuronal death.Q48525982
Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in ratsQ48721941
BACE1 Dependent Neuregulin Proteolysis.Q51866415
Frequency and prognostic value of cognitive disorders in stroke patients.Q51948054
Expression and distribution of beta amyloid precursor protein and beta amyloid peptide in reactive astrocytes after transient middle cerebral artery occlusion.Q53243101
Effect of hypotension severity on hippocampal CA1 neurons in a rat global ischemia modelQ74312894
Poor recovery of mitochondrial redox state in CA1 after transient forebrain ischemia in gerbilsQ77520523
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)932823
P577publication date2012-03-13
P1433published inEvidence-based Complementary and Alternative MedicineQ5418319
P1476titlePaeonol Protects Memory after Ischemic Stroke via Inhibiting β-Secretase and Apoptosis
P478volume2012

Reverse relations

cites work (P2860)
Q38859767A Pharmacological Review of Bioactive Constituents of Paeonia lactiflora Pallas and Paeonia veitchii Lynch
Q36898656Amyloidosis in Alzheimer's Disease: The Toxicity of Amyloid Beta (A β ), Mechanisms of Its Accumulation and Implications of Medicinal Plants for Therapy
Q26752935An Analysis of the Combination Frequencies of Constituent Medicinal Herbs in Prescriptions for the Treatment of Stroke in Korean Medicine: Determination of a Group of Candidate Prescriptions for Universal Use
Q37375693Electroacupuncture-Induced Neuroprotection against Cerebral Ischemia in Rats: Role of the Dopamine D2 Receptor
Q88790824Oleanolic Acid Ameliorates Aβ25-35 Injection-induced Memory Deficit in Alzheimer's Disease Model Rats by Maintaining Synaptic Plasticity
Q42845036Puerarin partly counteracts the inflammatory response after cerebral ischemia/reperfusion via activating the cholinergic anti-inflammatory pathway
Q38798698Synthesis and Evaluation of Aminothiazole-Paeonol Derivatives as Potential Anticancer Agents

Search more.