Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en

scientific article published in March 1996

Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.70.3.1818-1827.1996
P932PMC publication ID190009
P698PubMed publication ID8627706

P50authorRobert G. WebsterQ2159171
P2093author name stringL V Gubareva
G J Hart
K G Murti
R Bethell
C R Penn
P2860cites workInfluenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or buddingQ24676721
Characterization of temperature sensitive influenza virus mutants defective in neuraminidaseQ27865285
Inhibition of influenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA): mechanism of actionQ27867721
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolutionQ28131812
Inhibition of influenza virus replication in mice by GG167 (4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid) is consistent with extracellular activity of viral neuraminidase (sialidase)Q28368367
4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitroQ28378588
Rational design of potent sialidase-based inhibitors of influenza virus replicationQ29616647
The determination of enzyme inhibitor constantsQ29618526
Emergence and apparent transmission of rimantadine-resistant influenza A virus in familiesQ30460018
Plaque inhibition assay for drug susceptibility testing of influenza virusesQ33729018
Structure of the catalytic and antigenic sites in influenza virus neuraminidaseQ34249841
Influenza virus neuraminidase: structure, antibodies, and inhibitorsQ34318113
Crystallographic detection of a second ligand binding site in influenza virus hemagglutininQ36771495
Influenzavirus neuraminidase and neuraminidase-inhibition test proceduresQ36786074
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Emergence and possible transmission of amantadine-resistant viruses during nursing home outbreaks of influenza A (H3N2).Q37513512
Infectious entry pathway of influenza virus in a canine kidney cell lineQ41439180
Inhibition of the growth of influenza viruses in vitro by 4-guanidino-2,4-dideoxy-N-acetylneuraminic acidQ42282978
Biologic potential of amantadine-resistant influenza A virus in an avian modelQ43714146
Electrophoretic analysis of iodine-labeled influenza virus RNA segmentsQ43815502
Effects of sialylation of influenza virions on their interactions with host cells and erythrocytesQ44081932
2,3-didehydro-2,4-dideoxy-4-guanidino-N-acetyl-D-neuraminic acid (4-guanidino-Neu5Ac2en) is a slow-binding inhibitor of sialidase from both influenza A virus and influenza B virusQ45772671
Effects of hexose starvation and the role of sialic acid in influenza virus releaseQ45794047
Evidence for host-cell selection of influenza virus antigenic variantsQ45804806
Susceptibility of different strains of influenza A virus to the inhibitory effects of 2-deoxy-2,3-dehydro-n-trifluoracetylneuraminic acid (FANA).Q45883558
Amantadine-resistance as a Genetic Marker for Influenza VirusesQ54595307
In vivo Selection of an Influenza A2 Strain resistant to AmantadineQ71478276
Inhibition of sialidases from viral, bacterial and mammalian sources by analogues of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid modified at the C-4 positionQ72895734
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectinfluenza A virusQ834390
P304page(s)1818-1827
P577publication date1996-03-01
P1433published inJournal of VirologyQ1251128
P1476titleCharacterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en
P478volume70

Reverse relations

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