Maintenance of Nef-mediated modulation of major histocompatibility complex class I and CD4 after sexual transmission of human immunodeficiency virus type 1

scientific article published on 28 February 2007

Maintenance of Nef-mediated modulation of major histocompatibility complex class I and CD4 after sexual transmission of human immunodeficiency virus type 1 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01793-06
P932PMC publication ID1900175
P698PubMed publication ID17329339
P5875ResearchGate publication ID6477924

P50authorSergei L. Kosakovsky PondQ55456380
Davey SmithQ73235334
P2093author name stringM J Lewis
D D Richman
J C Guatelli
S K Pillai
O O Yang
S J Little
C M Noviello
P2860cites workNef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomesQ22009370
Genotypic and phenotypic characterization of HIV-1 patients with primary infectionQ22242245
Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef proteinQ22251058
HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.Q54148550
Reversion of CTL escape–variant immunodeficiency viruses in vivoQ56427919
Potential impact of recombination on sitewise approaches for detecting positive natural selectionQ59192521
Dynamics of viral variants in HIV-1 Nef and specific cytotoxic T lymphocytes in vivoQ71727882
HIV-1-specific CD8+ T cell responses and viral evolution in women and infantsQ81447131
Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infectionQ24538985
The rapid generation of mutation data matrices from protein sequencesQ27860880
Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipientsQ28284190
Not so different after all: a comparison of methods for detecting amino acid sites under selectionQ28306719
HyPhy: hypothesis testing using phylogeniesQ29013475
Datamonkey: rapid detection of selective pressure on individual sites of codon alignmentsQ29615126
The HIV-1 Nef protein as a target for antiretroviral therapyQ30160188
Site-to-site variation of synonymous substitution ratesQ31000547
Adaptation to different human populations by HIV-1 revealed by codon-based analysesQ33247450
Semen-specific genetic characteristics of human immunodeficiency virus type 1 env.Q33717839
Characterization of human immunodeficiency virus type 1 (HIV-1) envelope variation and neutralizing antibody responses during transmission of HIV-1 subtype B.Q33780595
Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viral RNA levelsQ33780649
Sequence variations in human immunodeficiency virus type 1 Nef are associated with different stages of diseaseQ33815169
CD4 down-modulation by human immunodeficiency virus type 1 Nef correlates with the efficiency of viral replication and with CD4(+) T-cell depletion in human lymphoid tissue ex vivoQ33847490
Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolutionQ34092644
Sexual transmission of single human immunodeficiency virus type 1 virions encoding highly polymorphic multisite cytotoxic T-lymphocyte escape variantsQ34123849
Dynamic evolution of the human immunodeficiency virus type 1 pathogenic factor, Nef.Q34302168
Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic.Q34327073
Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytesQ34999681
Acidic di-leucine motif essential for AP-3-dependent sorting and restriction of the functional specificity of the Vam3p vacuolar t-SNARE.Q36255662
Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivoQ36650992
Frequent transmission of cytotoxic-T-lymphocyte escape mutants of human immunodeficiency virus type 1 in the highly HLA-A24-positive Japanese populationQ36683968
Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variantQ37356747
Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef.Q38318792
Grossly defective nef gene sequences in a human immunodeficiency virus type 1-seropositive long-term nonprogressorQ39578202
Modulation of different human immunodeficiency virus type 1 Nef functions during progression to AIDSQ39605895
Evasion of cytotoxic T lymphocytes is a functional constraint maintaining HIV-1 Nef expressionQ40365272
Broadly Increased Sensitivity to Cytotoxic T Lymphocytes Resulting from Nef Epitope Escape MutationsQ40628580
Passive sexual transmission of human immunodeficiency virus type 1 variants and adaptation in new hostsQ41494621
A simple hierarchical approach to modeling distributions of substitution rates.Q42988209
HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversityQ43438499
GARD: a genetic algorithm for recombination detectionQ45134816
HIV-1 genomic RNA diversification following sexual and parenteral virus transmissionQ45873185
A genetic algorithm approach to detecting lineage-specific variation in selection pressure.Q45995621
Lack of neutralizing antibody response to HIV-1 predisposes to superinfection.Q46078929
Domain assembly, surface accessibility and sequence conservation in full length HIV-1 Nef.Q46586694
HIV evolution: CTL escape mutation and reversion after transmissionQ47211742
Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmissionQ47878972
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectsexually transmitted infectionQ12198
sexual transmissionQ45349134
P304page(s)4776-4786
P577publication date2007-02-28
P1433published inJournal of VirologyQ1251128
P1476titleMaintenance of Nef-mediated modulation of major histocompatibility complex class I and CD4 after sexual transmission of human immunodeficiency virus type 1
P478volume81

Reverse relations

cites work (P2860)
Q44859455Dynamic range of Nef functions in chronic HIV-1 infection
Q35156765Genotypic and functional impact of HIV-1 adaptation to its host population during the North American epidemic
Q34995124HIV-1 Nef sequence and functional compartmentalization in the gut is not due to differential cytotoxic T lymphocyte selective pressure
Q34657046HIV-1 neutralizing antibody response and viral genetic diversity characterized with next generation sequencing
Q47555873HLA Class I Downregulation by HIV-1 Variants from Subtype C Transmission Pairs
Q33826963High viremia is associated with high levels of in vivo major histocompatibility complex class I Downregulation in rhesus macaques infected with simian immunodeficiency virus SIVmac239.
Q36404189Human leukocyte antigen (HLA) class I down-regulation by human immunodeficiency virus type 1 negative factor (HIV-1 Nef): what might we learn from natural sequence variants?
Q36155465Immune selection in vitro reveals human immunodeficiency virus type 1 Nef sequence motifs important for its immune evasion function in vivo
Q36320655Impact of seminal cytomegalovirus replication on HIV-1 dynamics between blood and semen
Q33900388Ineffectual targeting of HIV-1 Nef by cytotoxic T lymphocytes in acute infection results in no functional impairment or viremia reduction.
Q40238313Molecular Features of the V1-V4 Coding Region of Sexually Transmitted Human Immunodeficiency Virus Type 1.
Q34613552Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure
Q33517082Phylogenetic analysis of population-based and deep sequencing data to identify coevolving sites in the nef gene of HIV-1.
Q33317659Recombinant gas vesicles from Halobacterium sp. displaying SIV peptides demonstrate biotechnology potential as a pathogen peptide delivery vehicle
Q36496515Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences
Q46281150Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals
Q39818825Simultaneous assessment of CD4 and MHC-I downregulation by Nef primary isolates in the context of infection
Q37086886Viral Evolution and Cytotoxic T Cell Restricted Selection in Acute Infant HIV-1 Infection