scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0092-8674(00)80715-1 |
P8608 | Fatcat ID | release_h65263jgavgw5k3cpx7565y5pi |
P3181 | OpenCitations bibliographic resource ID | 2579362 |
P698 | PubMed publication ID | 10199403 |
P2093 | author name string | D Trono | |
F Gu | |||
J Gruenberg | |||
J L Carpentier | |||
M Foti | |||
N Demaurex | |||
V Piguet | |||
P2860 | cites work | Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors | Q22008843 |
Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein | Q22251058 | ||
Serine phosphorylation-independent downregulation of cell-surface CD4 by nef | Q22251290 | ||
Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4 | Q24323265 | ||
Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain | Q24336240 | ||
Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain | Q24336554 | ||
Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling | Q24532104 | ||
Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes | Q24533226 | ||
In migrating fibroblasts, recycling receptors are concentrated in narrow tubules in the pericentriolar area, and then routed to the plasma membrane of the leading lamella | Q24657613 | ||
An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes | Q24671983 | ||
Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes | Q24672025 | ||
Nef-mediated clathrin-coated pit formation | Q24678715 | ||
Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity | Q24682806 | ||
A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains | Q27913878 | ||
Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum | Q27938624 | ||
Association of coatomer proteins with the beta-receptor for platelet-derived growth factor | Q28242587 | ||
PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization | Q28278951 | ||
Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients | Q28284190 | ||
A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor | Q28288514 | ||
A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4 | Q28288524 | ||
Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection | Q28304773 | ||
Coatomer interaction with di-lysine endoplasmic reticulum retention motifs | Q28609806 | ||
A Role for Acidic Residues in Di-leucine Motif-based Targeting to the Endocytic Pathway | Q28612864 | ||
The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase | Q28647550 | ||
Importance of the nef gene for maintenance of high virus loads and for development of AIDS | Q29618369 | ||
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain | Q29618472 | ||
Signal transduction by lymphocyte antigen receptors | Q29619894 | ||
Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking | Q30175880 | ||
The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR. | Q30176862 | ||
The cytoplasmic domain of P-selectin contains a sorting determinant that mediates rapid degradation in lysosomes | Q30442254 | ||
Tubular early endosomal networks in AtT20 and other cells | Q33404259 | ||
New COP1-binding motifs involved in ER retrieval | Q33890112 | ||
The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane | Q34418242 | ||
Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules | Q34468033 | ||
Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis | Q35845204 | ||
Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro | Q36220495 | ||
Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells. | Q36234444 | ||
ADP-ribosylation factor 6 regulates a novel plasma membrane recycling pathway | Q36273935 | ||
Functional dissection of COP-I subunits in the biogenesis of multivesicular endosomes | Q36274983 | ||
A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments. | Q36382769 | ||
Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4. | Q36625495 | ||
The role of clathrin, adaptors and dynamin in endocytosis | Q40647427 | ||
A lipid associated with the antiphospholipid syndrome regulates endosome structure and function | Q41056430 | ||
Inhibition of endosome function in CHO cells bearing a temperature-sensitive defect in the coatomer (COPI) component epsilon-COP. | Q41067848 | ||
Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation | Q41225968 | ||
Targeting of a lysosomal membrane protein: a tyrosine-containing endocytosis signal in the cytoplasmic tail of lysosomal acid phosphatase is necessary and sufficient for targeting to lysosomes. | Q41229177 | ||
Linking cargo to vesicle formation: receptor tail interactions with coat proteins. | Q41566699 | ||
An alpha-helical signal in the cytosolic domain of the interleukin 2 receptor beta chain mediates sorting towards degradation after endocytosis | Q42805931 | ||
Beta-COP is essential for biosynthetic membrane transport from the endoplasmic reticulum to the Golgi complex in vivo | Q45345741 | ||
Nef--an adaptor adaptor? | Q47686975 | ||
The role of endosomes and lysosomes in MHC class II functioning | Q47927773 | ||
HIV-1 regulatory/accessory genes: keys to unraveling viral and host cell biology | Q47956025 | ||
HIV-1 auxiliary proteins: making connections in a dying cell | Q47964324 | ||
HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. | Q54148550 | ||
Myristoylation-enhanced binding of the HIV-1 Nef protein to T cell skeletal matrix. | Q54649040 | ||
Endocytosis | Q57374715 | ||
The mannose 6-phosphate receptor and the biogenesis of lysosomes | Q57960197 | ||
HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product | Q59048755 | ||
Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins | Q59068188 | ||
Cytoplasmic coat proteins involved in endosome function | Q70787141 | ||
Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain | Q72591871 | ||
HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization | Q72610545 | ||
Mechanism of acidification of the trans-Golgi network (TGN). In situ measurements of pH using retrieval of TGN38 and furin from the cell surface | Q74088770 | ||
Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice | Q77470803 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 63-73 | |
P577 | publication date | 1999-04-02 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes | |
P478 | volume | 97 |
Q37110624 | A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex |
Q28768294 | A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2. |
Q34862136 | A novel adhesion pathway that regulates dendritic cell trafficking and T cell interactions |
Q39972438 | A selective autophagy pathway that degrades gluconeogenic enzymes during catabolite inactivation |
Q35531422 | ADP ribosylation factor 1 activity is required to recruit AP-1 to the major histocompatibility complex class I (MHC-I) cytoplasmic tail and disrupt MHC-I trafficking in HIV-1-infected primary T cells |
Q40972454 | AP-2 Is the Crucial Clathrin Adaptor Protein for CD4 Downmodulation by HIV-1 Nef in Infected Primary CD4+ T Cells |
Q24527321 | Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex |
Q30332406 | Amplification of a complete simian immunodeficiency virus genome from fecal RNA of a wild chimpanzee |
Q35160402 | Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells |
Q36673300 | Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions |
Q34999872 | At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis |
Q35024523 | Autophagy and HIV |
Q37280434 | Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages |
Q35400103 | CD4 and MHC class 1 down-modulation activities of nef alleles from brain- and lymphoid tissue-derived primary HIV-1 isolates |
Q36015423 | CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable |
Q40478558 | CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms. |
Q41896636 | COPA and SLC4A4 are required for cellular entry of arginine-rich peptides |
Q46651638 | Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells |
Q41989123 | Characterization and molecular basis of the oligomeric structure of HIV-1 nef protein |
Q24290610 | Cloning of ACP33 as a novel intracellular ligand of CD4 |
Q27667185 | Conformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assembly |
Q30175327 | Conservation of the central proline-rich (PxxP) motifs of human immunodeficiency virus type 1 Nef protein during the disease progression in two hemophiliac patients |
Q37146655 | Cooperative assembly and misfolding of CFTR domains in vivo. |
Q28204447 | DC-SIGN: escape mechanism for pathogens |
Q30306643 | Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation |
Q40409587 | Detection of human immunodeficiency virus type 1 Nef and CD4 physical interaction in living human cells by using bioluminescence resonance energy transfer |
Q40014256 | Differential control of CXCR4 and CD4 downregulation by HIV-1 Gag. |
Q39606016 | Direct in vitro binding of full-length human immunodeficiency virus type 1 Nef protein to CD4 cytoplasmic domain |
Q39539928 | Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation. |
Q30838641 | Diverting a protein from its cellular location by intracellular antibodies. The case of p21Ras |
Q39455569 | Down-modulation of CD8αβ is a fundamental activity of primate lentiviral Nef proteins |
Q21090808 | Down-regulation of CTLA-4 by HIV-1 Nef protein |
Q35785393 | Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor. |
Q73615689 | Downregulation of CD4 is required for maintenance of viral infectivity of HIV-1 |
Q40196866 | Downregulation of gamma interferon receptor 1 by Kaposi's sarcoma-associated herpesvirus K3 and K5. |
Q44292825 | Dynamic Nef and Nef dynamics: how structure could explain the complex activities of this small HIV protein |
Q34302168 | Dynamic evolution of the human immunodeficiency virus type 1 pathogenic factor, Nef. |
Q50706347 | Dynamic interaction of HIV-1 Nef with the clathrin-mediated endocytic pathway at the plasma membrane. |
Q35623173 | Dynamics of endosomal sorting |
Q35800393 | Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef. |
Q44252805 | Effects of HIV-1 Nef on retrograde transport from the plasma membrane to the endoplasmic reticulum. |
Q28115639 | Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches |
Q28469341 | Emergence of recombinant forms of HIV: dynamics and scaling |
Q34286096 | Endocytosis and signaling cascades: a close encounter |
Q34156695 | Endocytosis in viral replication |
Q35989046 | Endosome-to-cytosol transport of viral nucleocapsids |
Q34120725 | Estimating Frequencies of Minority Nevirapine-Resistant Strains in Chronically HIV-1-Infected Individuals Naïve to Nevirapine by Using Stochastic Simulations and a Mathematical Model |
Q42020354 | Fas engagement induces the maturation of dendritic cells (DCs), the release of interleukin (IL)-1beta, and the production of interferon gamma in the absence of IL-12 during DC-T cell cognate interaction: a new role for Fas ligand in inflammatory res |
Q33837307 | Genetic and functional diversity of human immunodeficiency virus type 1 subtype B Nef primary isolates |
Q31112668 | Guanidine alkaloid analogs as inhibitors of HIV-1 Nef interactions with p53, actin, and p56lck. |
Q39641516 | HIV Type 1 Nef is released from infected cells in CD45(+) microvesicles and is present in the plasma of HIV-infected individuals |
Q34033122 | HIV accessory proteins: multifunctional components of a complex system. |
Q33852032 | HIV dynamics with multiple infections of target cells |
Q37901625 | HIV immune evasion disruption of antigen presentation by the HIV Nef protein |
Q52668674 | HIV-1 Nef antagonizes SERINC5 restriction by downregulation of SERINC5 via the endosome/lysosome system. |
Q28202882 | HIV-1 Nef control of cell signalling molecules: multiple strategies to promote virus replication |
Q24602320 | HIV-1 Nef disrupts intracellular trafficking of major histocompatibility complex class I, CD4, CD8, and CD28 by distinct pathways that share common elements |
Q28202962 | HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway |
Q44807433 | HIV-1 Nef enhances both membrane expression and virion incorporation of Env products. A model for the Nef-dependent increase of HIV-1 infectivity |
Q22248080 | HIV-1 Nef impairs MHC class II antigen presentation and surface expression |
Q24338895 | HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation |
Q61319055 | HIV-1 Nef protects human-monocyte-derived macrophages from HIV-1-induced apoptosis |
Q22253302 | HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes |
Q42953201 | HIV-1 Nef regulates the release of superoxide anions from human macrophages. |
Q40453368 | HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling. |
Q33363091 | HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells |
Q38830464 | HIV-1 Nef: Taking Control of Protein Trafficking |
Q57065358 | HIV-1 Trafficking to the Dendritic Cell-T-Cell Infectious Synapse Uses a Pathway of Tetraspanin Sorting to the Immunological Synapse |
Q34875979 | HIV-1 replication cycle |
Q30168004 | Hck SH3 domain-dependent abrogation of Nef-induced class 1 MHC down-regulation |
Q35058535 | Hide, shield and strike back: how HIV-infected cells avoid immune eradication |
Q37590720 | High levels of anti-Nef antibodies may prevent AIDS disease progression in vertically HIV-1-infected infants |
Q90440626 | How HIV Nef Proteins Hijack Membrane Traffic To Promote Infection |
Q33930465 | Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta |
Q30312050 | Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity |
Q24527208 | Human immunodeficiency virus type 1 Nef mediates sustained membrane expression of tumor necrosis factor and the related cytokine LIGHT on activated T cells |
Q37232786 | Human immunodeficiency virus type 1 Nef protein targets CD4 to the multivesicular body pathway. |
Q33850973 | Human immunodeficiency virus type 1 Nef-induced CD4 cell surface downregulation is inhibited by ikarugamycin |
Q36499676 | Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways |
Q39966059 | Human immunodeficiency virus type 1 nef expression prevents AP-2-mediated internalization of the major histocompatibility complex class II-associated invariant chain. |
Q36404189 | Human leukocyte antigen (HLA) class I down-regulation by human immunodeficiency virus type 1 negative factor (HIV-1 Nef): what might we learn from natural sequence variants? |
Q58742287 | Identification of Novel Subcellular Localization and Trafficking of HIV-1 Nef Variants from Reference Strains G (F1.93.HH8793) and H (BE.93.VI997) |
Q37034627 | Identification of potential drug targets using genomics and proteomics: a systems approach |
Q33944148 | Impaired regulation of HLA-DR expression in human immunodeficiency virus-infected monocytes |
Q56923692 | In vitro treatment of human monocytes/macrophages with myristoylated recombinant Nef of human immunodeficiency virus type 1 leads to the activation of mitogen-activated protein kinases, IkappaB kinases, and interferon regulatory factor 3 and to the r |
Q39443718 | In-silico designing of a potent analogue against HIV-1 Nef protein and protease by predicting its interaction network with host cell proteins |
Q34283497 | Interaction of HIV-1 Nef protein with the host protein Alix promotes lysosomal targeting of CD4 receptor. |
Q40269589 | Interactions between Nef and AIP1 proliferate multivesicular bodies and facilitate egress of HIV-1. |
Q35024084 | Intra- and intersubtype alternative Pak2-activating structural motifs of human immunodeficiency virus type 1 Nef |
Q33767582 | Intracellular protein traffic in lymphocytes: "how do I get THERE from HERE"? |
Q30407564 | Lack of adaptation to human tetherin in HIV-1 group O and P. |
Q34452109 | Lentivirus and foamy virus vectors: novel gene therapy tools |
Q24557417 | Leucine-specific, functional interactions between human immunodeficiency virus type 1 Nef and adaptor protein complexes |
Q35857424 | Maintenance of Nef-mediated modulation of major histocompatibility complex class I and CD4 after sexual transmission of human immunodeficiency virus type 1 |
Q59354268 | Masters of manipulation: Viral modulation of the immunological synapse |
Q37183848 | Mechanisms of HIV-1 Nef function and intracellular signaling |
Q24676355 | Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway |
Q35214569 | Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence |
Q42238101 | Modeling HIV-1 dynamics and fitness in cell culture across scales. |
Q38952060 | Modeling Viral Spread |
Q34156663 | Molecular structures of proteins involved in vesicle coat formation |
Q39644822 | Multiple endocytic trafficking pathways of MHC class I molecules induced by a Herpesvirus protein |
Q36684127 | Multiplicity of human immunodeficiency virus infections in lymphoid tissue |
Q24524045 | Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions |
Q56782203 | Mutations in thenefandvifgenes associated with progression to AIDS in elite controller and slow-progressor Patients |
Q49587948 | Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses. |
Q34185928 | Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner |
Q38260894 | Nef as a Proliferative Factor for Kidney Epithelial Cells in HIV-Associated Nephropathy |
Q40815179 | Nef binds p6* in GagPol during replication of human immunodeficiency virus type 1. |
Q34109778 | Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41. |
Q36255107 | Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation |
Q34436944 | Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors |
Q34186134 | Nef stimulates human immunodeficiency virus type 1 replication in primary T cells by enhancing virion-associated gp120 levels: coreceptor-dependent requirement for Nef in viral replication |
Q24563306 | Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways |
Q33851483 | Nef-induced CD4 downregulation: a diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to beta-COP. |
Q39852042 | Nef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase |
Q34755576 | Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells |
Q34999681 | Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes |
Q34552824 | Nef: agent of cell subversion |
Q24290827 | Negative factor from SIV binds to the catalytic subunit of the V-ATPase to internalize CD4 and to increase viral infectivity |
Q35219295 | Pathogens target DC-SIGN to influence their fate DC-SIGN functions as a pathogen receptor with broad specificity |
Q93081405 | Plasma Membrane-Associated Restriction Factors and Their Counteraction by HIV-1 Accessory Proteins |
Q28145311 | Quantitative analysis of TIP47-receptor cytoplasmic domain interactions: implications for endosome-to-trans Golgi network trafficking |
Q37367728 | Reduction of Stat3 activity attenuates HIV-induced kidney injury |
Q21144277 | Regulation of the V-ATPase along the endocytic pathway occurs through reversible subunit association and membrane localization |
Q26767362 | Remodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and Persistence |
Q27931535 | Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes |
Q37183096 | Retroviral proteomics and interactomes: intricate balances of cell survival and viral replication |
Q30415417 | Role of Coatomer Protein I in Virus Replication |
Q22003751 | Roles of CD4 and coreceptors in binding, endocytosis, and proteolysis of gp120 envelope glycoproteins derived from human immunodeficiency virus type 1 |
Q39601928 | Securin and separase modulate membrane traffic by affecting endosomal acidification |
Q34156651 | Selective inhibition of adaptor complex-mediated vesiculation |
Q42223515 | Sequence heterogeneity in human immunodeficiency virus type 1 nef in patients presenting with rapid progression and delayed progression to AIDS. |
Q24522550 | Structure--function relationships in HIV-1 Nef. |
Q24531411 | Subunit H of the V-ATPase involved in endocytosis shows homology to beta-adaptins |
Q92177481 | TIM-mediated inhibition of HIV-1 release is antagonized by Nef but potentiated by SERINC proteins |
Q33797892 | Taking multiple infections of cells and recombination into account leads to small within-host effective-population-size estimates of HIV-1 |
Q93190169 | Temporary Reduction of Membrane CD4 with the Antioxidant MnTBAP Is Sufficient to Prevent Immune Responses Induced by Gene Transfer |
Q30175300 | The HIV Nef protein alters Ca(2+) signaling in myelomonocytic cells through SH3-mediated protein-protein interactions |
Q30160188 | The HIV-1 Nef protein as a target for antiretroviral therapy |
Q47554270 | The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells |
Q37198515 | The Mamu B 17-restricted SIV Nef IW9 to TW9 mutation abrogates correct epitope processing and presentation without loss of replicative fitness |
Q33574322 | The TOR complex 1 is distributed in endosomes and in retrograde vesicles that form from the vacuole membrane and plays an important role in the vacuole import and degradation pathway |
Q34021500 | The Vpu protein: new concepts in virus release and CD4 down-modulation |
Q38218107 | The activity of Nef on HIV-1 infectivity |
Q37564872 | The biology of the sodium iodide symporter and its potential for targeted gene delivery |
Q36342606 | The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments |
Q33683328 | The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors |
Q34389525 | The endocytic pathway: a mosaic of domains |
Q33901672 | The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation |
Q38106813 | The key gluconeogenic enzyme fructose-1,6-bisphosphatase is secreted during prolonged glucose starvation and is internalized following glucose re-feeding via the non-classical secretory and internalizing pathways in Saccharomyces cerevisiae |
Q34745959 | The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components |
Q41842747 | The vacuolar import and degradation pathway merges with the endocytic pathway to deliver fructose-1,6-bisphosphatase to the vacuole for degradation |
Q33569799 | The vacuole import and degradation pathway utilizes early steps of endocytosis and actin polymerization to deliver cargo proteins to the vacuole for degradation |
Q28474857 | Timing the emergence of resistance to anti-HIV drugs with large genetic barriers |
Q43944990 | Transient surface delivery of invariant chain-MHC II complexes via endosomes: a quantitative study |
Q45345419 | Two independent regions of HIV-1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex. |
Q36266461 | Viral modulation of antigen presentation: manipulation of cellular targets in the ER and beyond |
Q47913815 | Vpu Exerts a Positive Effect on HIV-1 Infectivity by Down-modulating CD4 Receptor Molecules at the Surface of HIV-1-producing Cells |
Q24535092 | p56Lck anchors CD4 to distinct microdomains on microvilli |
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