| scholarly article | Q13442814 |
| P50 | author | Bridget Carragher | Q41629084 |
| P2093 | author name string | Ian J MacRae | |
| Clinton S Potter | |||
| Nabanita De | |||
| Keelan Z Guiley | |||
| Pick-Wei Lau | |||
| P2860 | cites work | In vitro reconstitution of the human RISC-loading complex | Q24305536 |
| Autoinhibition of human dicer by its internal helicase domain | Q24316912 | ||
| Structural insights into RNA processing by the human RISC-loading complex | Q24324404 | ||
| Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP | Q24539076 | ||
| Structure of the human Dicer-TRBP complex by electron microscopy | Q24600778 | ||
| Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease | Q24613058 | ||
| A monovalent streptavidin with a single femtomolar biotin binding site | Q24645981 | ||
| Homodimeric structure and double-stranded RNA cleavage activity of the C-terminal RNase III domain of human dicer | Q27648723 | ||
| Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage | Q27649833 | ||
| Structure of the Arabidopsis thaliana DCL4 DUF283 domain reveals a noncanonical double-stranded RNA-binding fold for protein-protein interaction | Q27659222 | ||
| The Inside-Out Mechanism of Dicers from Budding Yeasts | Q27670965 | ||
| Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA | Q27675053 | ||
| SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields | Q27860560 | ||
| UCSF Chimera--a visualization system for exploratory research and analysis | Q27860666 | ||
| EMAN: semiautomated software for high-resolution single-particle reconstructions | Q27860772 | ||
| A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA | Q27860813 | ||
| Origins and Mechanisms of miRNAs and siRNAs | Q27860822 | ||
| Role for a bidentate ribonuclease in the initiation step of RNA interference | Q27860832 | ||
| Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi | Q28218870 | ||
| Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain | Q28262499 | ||
| Inhibition of translational initiation by Let-7 MicroRNA in human cells | Q28265842 | ||
| Structural basis for double-stranded RNA processing by Dicer | Q28291591 | ||
| An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells | Q29547714 | ||
| Appion: an integrated, database-driven pipeline to facilitate EM image processing | Q29614288 | ||
| Automated molecular microscopy: the new Leginon system | Q29614290 | ||
| Single processing center models for human Dicer and bacterial RNase III | Q29618466 | ||
| R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway | Q29618468 | ||
| microRNA-directed phasing during trans-acting siRNA biogenesis in plants | Q29618562 | ||
| Automation of random conical tilt and orthogonal tilt data collection using feature-based correlation | Q31113691 | ||
| Maximum-likelihood multi-reference refinement for electron microscopy images | Q33213664 | ||
| Origin and evolution of the RIG-I like RNA helicase gene family | Q33436036 | ||
| Structural insights into RNA interference | Q33791962 | ||
| Substrate-specific kinetics of Dicer-catalyzed RNA processing | Q34422752 | ||
| Dicer's helicase domain discriminates dsRNA termini to promote an altered reaction mode | Q34700764 | ||
| Loqs-PD and R2D2 define independent pathways for RISC generation in Drosophila. | Q34947076 | ||
| siRNA repositioning for guide strand selection by human Dicer complexes | Q35128519 | ||
| Use of peptide libraries to map the substrate specificity of a peptide-modifying enzyme: a 13 residue consensus peptide specifies biotinylation in Escherichia coli. | Q36705248 | ||
| Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi | Q36933702 | ||
| A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs | Q36972141 | ||
| DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy | Q37401395 | ||
| Biogenesis and function of endogenous and exogenous siRNAs | Q37940383 | ||
| Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways | Q39751785 | ||
| Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions | Q40676456 | ||
| Structural determinants of RNA recognition and cleavage by Dicer | Q43466402 | ||
| Recognition of the pre-miRNA structure by Drosophila Dicer-1. | Q47070637 | ||
| Functional anatomy of the Drosophila microRNA-generating enzyme | Q47071173 | ||
| Physical and functional coupling of RNA-dependent RNA polymerase and Dicer in the biogenesis of endogenous siRNAs. | Q53024342 | ||
| P433 | issue | 4 | |
| P304 | page(s) | 436-440 | |
| P577 | publication date | 2012-03-18 | |
| P1433 | published in | Nature Structural & Molecular Biology | Q1071739 |
| P1476 | title | The molecular architecture of human Dicer | |
| P478 | volume | 19 |
| Q27681563 | A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer |
| Q36342253 | A comprehensive analysis of precursor microRNA cleavage by human Dicer |
| Q34464259 | A structure-based model of RIG-I activation |
| Q28088456 | A toolbox for miRNA analysis |
| Q90492949 | AGO unchained: Canonical and non-canonical roles of Argonaute proteins in mammals |
| Q52671487 | Are microRNAs Important Players in HIV-1 Infection? An Update. |
| Q46977021 | Biallelic DICER1 mutations occur in Wilms tumours. |
| Q36787591 | Biochemistry. Integrative structural biology |
| Q27001401 | Biogenesis and mechanism of action of small non-coding RNAs: insights from the point of view of structural biology |
| Q37255952 | CDC5, a DNA binding protein, positively regulates posttranscriptional processing and/or transcription of primary microRNA transcripts |
| Q53109067 | Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage. |
| Q87184037 | Characterization of a naturally occurring truncated Dicer |
| Q26746000 | Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers |
| Q52674256 | Comparing miRNA structure of mirtrons and non-mirtrons. |
| Q89783927 | Complexity in regulating microRNA biogenesis in cancer |
| Q36290029 | Coordinated activities of human dicer domains in regulatory RNA processing |
| Q38944970 | Cryo-EM of dynamic protein complexes in eukaryotic DNA replication |
| Q101148678 | DICER1-Associated Embryonal Rhabdomyosarcoma and Adenosarcoma of the Gynecologic Tract: Pathology, Molecular Genetics and Indications for Molecular Testing |
| Q38245164 | DICER1: mutations, microRNAs and mechanisms |
| Q36502340 | DOLORS: versatile strategy for internal labeling and domain localization in electron microscopy |
| Q49650355 | Dicer partner protein tunes the length of miRNAs using base-mismatch in the pre-miRNA stem |
| Q47561583 | Dicer uses distinct modules for recognizing dsRNA termini |
| Q34405708 | Dicer's role as an antiviral: still an enigma |
| Q24311911 | Dicer-TRBP complex formation ensures accurate mammalian microRNA biogenesis |
| Q38594054 | Dicer-related helicase 3 forms an obligate dimer for recognizing 22G-RNA. |
| Q58720618 | Discovery of microRNA-like RNAs during early fruiting body development in the model mushroom Coprinopsis cinerea |
| Q38335714 | Dissecting the roles of TRBP and PACT in double-stranded RNA recognition and processing of noncoding RNAs |
| Q38885005 | Drosophila dicer-2 cleavage is mediated by helicase- and dsRNA termini-dependent states that are modulated by Loquacious-PD. |
| Q38066334 | Duplex RNA activated ATPases (DRAs): platforms for RNA sensing, signaling and processing |
| Q26752006 | Emerging Role of miRNAs in the Drug Resistance of Gastric Cancer |
| Q38112460 | Engineering RNA-binding proteins for biology |
| Q36589329 | Ensemble analysis of primary microRNA structure reveals an extensive capacity to deform near the Drosha cleavage site. |
| Q34551032 | Evolution of RNA- and DNA-guided antivirus defense systems in prokaryotes and eukaryotes: common ancestry vs convergence |
| Q34317357 | Evolutionarily conserved roles of the dicer helicase domain in regulating RNA interference processing |
| Q34941884 | Fluorescence-based high-throughput screening of dicer cleavage activity. |
| Q35670556 | From guide to target: molecular insights into eukaryotic RNA-interference machinery. |
| Q92571451 | Generation of Virus- and dsRNA-Derived siRNAs with Species-Dependent Length in Insects |
| Q36339269 | Go hybrid: EM, crystallography, and beyond |
| Q38593783 | Helicases in Antiviral Immunity: Dual Properties as Sensors and Effectors |
| Q59790871 | High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension |
| Q37707480 | Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain |
| Q99238002 | Key Mechanistic Principles and Considerations Concerning RNA Interference |
| Q47654479 | Kinetic Analysis of Small Silencing RNA Production by Human and Drosophila Dicer Enzymes In Vitro |
| Q36204087 | LBSizeCleav: improved support vector machine (SVM)-based prediction of Dicer cleavage sites using loop/bulge length |
| Q38831787 | MiR-140-3p suppressed cell growth and invasion by downregulating the expression of ATP8A1 in non-small cell lung cancer |
| Q46461985 | MiRNA Biogenesis and Regulation of Diseases: An Overview |
| Q36569914 | MicroRNA biogenesis: regulating the regulators |
| Q38262497 | MicroRNA dysregulation as a prognostic biomarker in colorectal cancer |
| Q26864786 | MicroRNA-independent roles of the RNase III enzymes Drosha and Dicer |
| Q33634981 | Molecular mechanisms of Dicer: endonuclease and enzymatic activity |
| Q28290306 | Molecular mechanisms of RNA interference |
| Q35803408 | Monovalent Strep-Tactin for strong and site-specific tethering in nanospectroscopy. |
| Q41343667 | Nuclear phosphorylated Dicer processes double-stranded RNA in response to DNA damage |
| Q48114267 | Nuclear re-localization of Dicer in primary mouse embryonic fibroblast nuclei following DNA damage. |
| Q40128001 | Overexpression and purification of Dicer and accessory proteins for biochemical and structural studies |
| Q37493117 | Phosphate-binding pocket in Dicer-2 PAZ domain for high-fidelity siRNA production. |
| Q26751455 | Production of small RNAs by mammalian Dicer |
| Q26771810 | RNA Binding Proteins in the miRNA Pathway |
| Q38051973 | Rarely at rest: RNA helicases and their busy contributions to RNA degradation, regulation and quality control |
| Q91519226 | Regulation of microRNA biogenesis and its crosstalk with other cellular pathways |
| Q90947514 | Regulation of microRNA function in animals |
| Q26859171 | Renaissance of mammalian endogenous RNAi |
| Q26863693 | Ribonuclease III mechanisms of double-stranded RNA cleavage |
| Q26991911 | Sensing viral RNAs by Dicer/RIG-I like ATPases across species |
| Q38318677 | Sequence-specific inhibition of Dicer measured with a force-based microarray for RNA ligands |
| Q36009522 | Small-molecule approaches toward the targeting of oncogenic miRNAs: roadmap for the discovery of RNA modulators |
| Q36164105 | Stop the dicing in hematopoiesis: what have we learned? |
| Q47222627 | Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components. |
| Q49960749 | Structural basis of siRNA recognition by TRBP double-stranded RNA binding domains |
| Q24311742 | Structure of precursor microRNA's terminal loop regulates human Dicer's dicing activity by switching DExH/D domain |
| Q36912488 | Substrate-specific structural rearrangements of human Dicer |
| Q47988407 | Switches in Dicer Activity During Oogenesis and Early Development |
| Q37400278 | Synthetic pre-microRNAs reveal dual-strand activity of miR-34a on TNF-α. |
| Q54503440 | TWEAK Negatively Regulates Human Dicer. |
| Q37196915 | Terminal loop-mediated regulation of miRNA biogenesis: selectivity and mechanisms |
| Q47070471 | The C-terminal dsRNA-binding domain of Drosophila Dicer-2 is crucial for efficient and high-fidelity production of siRNA and loading of siRNA to Argonaute2. |
| Q38955995 | The Evolutionary Loss of RNAi Key Determinants in Kinetoplastids as a Multiple Sporadic Phenomenon |
| Q37122968 | The double-stranded RNA binding domain of human Dicer functions as a nuclear localization signal |
| Q34310927 | The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo |
| Q35786141 | The many faces of Dicer: the complexity of the mechanisms regulating Dicer gene expression and enzyme activities |
| Q54228570 | The microRNA Machinery. |
| Q34525711 | The role of human Dicer-dsRBD in processing small regulatory RNAs |
| Q38045141 | Toward a molecular understanding of RNA remodeling by DEAD-box proteins |
| Q54519528 | Turning Dicer on its head. |
| Q36896302 | ZO-2 silencing induces renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway |
| Q38248221 | microRNA biogenesis, degradation and activity in plants. |
| Q39107299 | microRNA-binding proteins: specificity and function. |
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