| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Y Chai | |
| J Iwata | |||
| C Parada | |||
| P2860 | cites work | Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion | Q24294844 |
| The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner | Q24308947 | ||
| Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome | Q24548457 | ||
| Marfan's syndrome | Q24553344 | ||
| A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4 | Q24606773 | ||
| Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development | Q24616861 | ||
| Functions and mechanisms of action of CCN matricellular proteins | Q24642303 | ||
| Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency | Q28115172 | ||
| Fate of the mammalian cardiac neural crest | Q28139176 | ||
| BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6 | Q28140674 | ||
| Pathogenesis of cleft palate in TGF-beta3 knockout mice | Q28141234 | ||
| Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice | Q28204189 | ||
| Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice | Q28204809 | ||
| Chromosomal microdeletions: dissecting del22q11 syndrome | Q28206335 | ||
| Smad-dependent and Smad-independent pathways in TGF-beta family signalling | Q28208250 | ||
| A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2 | Q28236792 | ||
| Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway | Q28239297 | ||
| Associations of folate and choline metabolism gene polymorphisms with orofacial clefts | Q28257853 | ||
| Biological mechanisms in palatogenesis and cleft palate. | Q37364951 | ||
| Transforming growth factor-beta 3 is required for secondary palate fusion | Q37373842 | ||
| Microduplication 22q11.2: a new chromosomal syndrome | Q37405004 | ||
| Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of palate and rescues cleft palate in Msx1-null mice | Q37429788 | ||
| Importance of gene-environment interactions in the etiology of selected birth defects. | Q37491262 | ||
| The genetics of isolated orofacial clefts: from genotypes to subphenotypes | Q37543614 | ||
| New regulatory mechanisms of TGF-beta receptor function | Q37569258 | ||
| Tubular epithelial cell dedifferentiation is driven by the helix-loop-helix transcriptional inhibitor Id1. | Q38306043 | ||
| Palate development | Q39577154 | ||
| Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression | Q39790068 | ||
| Epithelial-mesenchymal interactions during vertebrate palatogenesis. | Q40192220 | ||
| Neural crest and cardiovascular patterning. | Q40447081 | ||
| Cleft palate: players, pathways, and pursuits | Q40904554 | ||
| Smad2 role in mesoderm formation, left-right patterning and craniofacial development | Q41027581 | ||
| Programmed cell death and cell transformation in craniofacial development | Q41094480 | ||
| TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis | Q41159403 | ||
| Neural crest formation in the head of the mouse embryo as observed using a new histological technique | Q41469009 | ||
| TGF-beta receptor signaling | Q41659039 | ||
| Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts | Q41700398 | ||
| Alteration of medial-edge epithelium cell adhesion in two Tgf-beta3 null mouse strains. | Q41781930 | ||
| Differential expression of TGF beta isoforms in murine palatogenesis. | Q41903122 | ||
| Medial edge epithelium transforms to mesenchyme after embryonic palatal shelves fuse | Q42489698 | ||
| Medial edge epithelium fate traced by cell lineage analysis during epithelial-mesenchymal transformation in vivo | Q43704984 | ||
| Reduced recurrence of orofacial clefts after periconceptional supplementation with high-dose folic acid and multivitamins | Q46092048 | ||
| Generating and modifying DiGeorge syndrome-like phenotypes in model organisms: is there a common genetic pathway? | Q46181216 | ||
| Vital dye analysis of cranial neural crest cell migration in the mouse embryo | Q46333344 | ||
| Overexpression of Smad2 in Tgf-beta3-null mutant mice rescues cleft palate | Q46377967 | ||
| Targeting TGF-beta and the extracellular matrix in Marfan's syndrome | Q46498091 | ||
| Cell autonomous requirement for Tgfbr2 in the disappearance of medial edge epithelium during palatal fusion | Q46627704 | ||
| TGFbeta-mediated FGF signaling is crucial for regulating cranial neural crest cell proliferation during frontal bone development | Q46837830 | ||
| CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts | Q46949378 | ||
| Phenotypic consequences of transforming growth factor beta1 gene ablation in murine embryonic fibroblasts: autocrine control of cell proliferation and extracellular matrix biosynthesis | Q48000633 | ||
| TGFBR1 and TGFBR2 mutations in patients with features of Marfan syndrome and Loeys-Dietz syndrome. | Q49080920 | ||
| TGFbeta1 and TGFbeta3 are partially redundant effectors in brain vascular morphogenesis. | Q51961889 | ||
| Cardiovascular development and the colonizing cardiac neural crest lineage. | Q51981254 | ||
| TGF-beta3 is required for the adhesion and intercalation of medial edge epithelial cells during palate fusion. | Q52118523 | ||
| Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube. | Q52174011 | ||
| Transforming growth factor-beta signalling in extraembryonic mesoderm is required for yolk sac vasculogenesis in mice. | Q52175742 | ||
| Autoimmune Sjögren's-like lesions in salivary glands of TGF-beta1-deficient mice are inhibited by adhesion-blocking peptides. | Q52200537 | ||
| Connective tissue growth factor (CTGF/CCN2) is a downstream mediator for TGF-beta1-induced extracellular matrix production in osteoblasts. | Q53585938 | ||
| Rac1 signaling regulates CTGF/CCN2 gene expression via TGFbeta/Smad signaling in chondrocytes. | Q54517770 | ||
| Genes causing clefting syndromes as candidates for non-syndromic cleft lip with or without cleft palate: a family-based association study | Q56991987 | ||
| Congenital heart disease in mice deficient for the DiGeorge syndrome region | Q59062255 | ||
| Medial edge epithelial cell fate during palatal fusion | Q73642071 | ||
| Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis | Q74578263 | ||
| Induction of cleft palate in mice by cortisone and its reduction by vitamins | Q78333160 | ||
| Study of 400 pregnancies with birth of cleft lip-palate infants; protective effect of folic acid and vitamin B6 therapy | Q78438353 | ||
| Cleft lip and palate | Q79903440 | ||
| Interferon regulatory factor 6 (IRF6) is associated with oral-facial cleft in individuals that originate in South America | Q80802431 | ||
| Cleft lip and palate | Q84548187 | ||
| Aneurysm syndromes caused by mutations in the TGF-beta receptor | Q28259654 | ||
| Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction | Q28284617 | ||
| Angiotensin II blockade and aortic-root dilation in Marfan's syndrome | Q28285199 | ||
| An update on the aetiology of orofacial clefts | Q28287504 | ||
| Smads: transcriptional activators of TGF-beta responses | Q28292325 | ||
| 7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome | Q28354262 | ||
| Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice | Q28361871 | ||
| Shox2-deficient mice exhibit a rare type of incomplete clefting of the secondary palate | Q28506891 | ||
| Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos | Q28508310 | ||
| Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin | Q28511724 | ||
| Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects | Q28512647 | ||
| Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis | Q28585241 | ||
| Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate | Q28587665 | ||
| TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes | Q28592444 | ||
| Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta | Q28594801 | ||
| Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation | Q29615365 | ||
| Specificity and versatility in tgf-beta signaling through Smads | Q29616324 | ||
| Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis | Q29616631 | ||
| Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome | Q29618845 | ||
| Transcriptional control by the TGF-beta/Smad signaling system | Q29618985 | ||
| Non-Smad pathways in TGF-beta signaling | Q29620040 | ||
| Elf3 encodes a novel 200-kD beta-spectrin: role in liver development. | Q31917712 | ||
| Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities. | Q32024327 | ||
| Cleft lip and palate genetics and application in early embryological development | Q33671456 | ||
| The role of folic acid in oral clefting | Q33696039 | ||
| Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells | Q33717696 | ||
| Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome | Q33915737 | ||
| The impact of orofacial clefts on quality of life and healthcare use and costs | Q34002697 | ||
| Folic acid and orofacial clefts: a review of the evidence | Q34068983 | ||
| Heterozygous TGFBR2 mutations in Marfan syndrome | Q34331334 | ||
| Recent progress towards a molecular understanding of Marfan syndrome | Q34465738 | ||
| Fetal diagnosis and treatment of craniomaxillofacial anomalies | Q34850477 | ||
| Cholesterol precursors and facial clefting | Q35009494 | ||
| TGF-beta signaling and its functional significance in regulating the fate of cranial neural crest cells | Q35134876 | ||
| The immunophilin FKBP12: a molecular guardian of the TGF-beta family type I receptors | Q35650907 | ||
| The complex genetics of cleft lip and palate | Q35680160 | ||
| TGF-beta mediated FGF10 signaling in cranial neural crest cells controls development of myogenic progenitor cells through tissue-tissue interactions during tongue morphogenesis | Q35913326 | ||
| TGF-beta mediated Msx2 expression controls occipital somites-derived caudal region of skull development | Q35915698 | ||
| The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice | Q36008239 | ||
| The role of TGF-beta signaling in regulating chondrogenesis and osteogenesis during mandibular development | Q36136659 | ||
| Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2. | Q36258971 | ||
| TGF-beta3-induced palatogenesis requires matrix metalloproteinases | Q36284069 | ||
| Regional regulation of palatal growth and patterning along the anterior-posterior axis in mice | Q36325019 | ||
| Tgfb1 expressed in the Tgfb3 locus partially rescues the cleft palate phenotype of Tgfb3 null mutants | Q36326693 | ||
| Quality improvement of cleft lip and palate treatment | Q36422103 | ||
| Recent advances in craniofacial morphogenesis | Q36471176 | ||
| Conductive hearing loss and otopathology in cleft palate patients | Q36490935 | ||
| Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta | Q36663630 | ||
| Tissue-specific expression of Cre recombinase from the Tgfb3 locus | Q36726025 | ||
| Legal considerations in the management of cleft lip and palate | Q36747447 | ||
| Cleft palate speech and velopharyngeal dysfunction: the approach of the speech therapist. | Q36762310 | ||
| TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner | Q36777110 | ||
| Extracellular matrix and growth factors in the pathogenesis of some craniofacial malformations. | Q36912377 | ||
| Tobacco smoking and oral clefts: a meta-analysis. | Q36980177 | ||
| Signaling through Tgf-beta type I receptor Alk5 is required for upper lip fusion. | Q36995688 | ||
| Genetic Factors and Orofacial Clefting | Q37005596 | ||
| Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development | Q37029572 | ||
| TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta | Q37052635 | ||
| Unraveling human cleft lip and palate research | Q37064729 | ||
| Team care of the patient with cleft lip and palate | Q37142480 | ||
| Tissue engineering in cleft palate and other congenital malformations. | Q37143936 | ||
| Current surgical practices in cleft care: unilateral cleft lip repair | Q37153553 | ||
| Newborn hearing screening in infants with cleft palates | Q37212738 | ||
| Recent advances in presurgical molding in cleft lip and palate | Q37216197 | ||
| New insights in the pathogenesis of aortic aneurysms | Q37217611 | ||
| Feeding and swallowing dysfunction in genetic syndromes | Q37223574 | ||
| Cell autonomous requirement for TGF-beta signaling during odontoblast differentiation and dentin matrix formation | Q37247517 | ||
| Smad4 is required to regulate the fate of cranial neural crest cells | Q37247522 | ||
| Autoimmunity associated with TGF-beta1-deficiency in mice is dependent on MHC class II antigen expression | Q37361208 | ||
| P433 | issue | 8 | |
| P304 | page(s) | 733-744 | |
| P577 | publication date | 2011-03-13 | |
| P1433 | published in | Oral Diseases | Q15724675 |
| P1476 | title | The mechanism of TGF-β signaling during palate development | |
| P478 | volume | 17 |
| Q51318688 | 7-Dehydrocholesterol (7-DHC), But Not Cholesterol, Causes Suppression of Canonical TGF-β Signaling and Is Likely Involved in the Development of Atherosclerotic Cardiovascular Disease (ASCVD). |
| Q41909723 | Analysis of dermal fibroblasts isolated from neonatal and child cleft lip and adult skin: Developmental implications on reconstructive surgery. |
| Q37122742 | CTGF mediates Smad-dependent transforming growth factor β signaling to regulate mesenchymal cell proliferation during palate development |
| Q38287765 | Cleft palate: a clinical review |
| Q64253772 | Coupling between dynamic 3D tissue architecture and BMP morphogen signaling during wing morphogenesis |
| Q47156515 | Determinants of orofacial clefting I: Effects of 5-Aza-2'-deoxycytidine on cellular processes and gene expression during development of the first branchial arch |
| Q57175359 | Development of Normal and Cleft Palate: A Central Role for Connective Tissue Growth Factor (CTGF)/CCN2 |
| Q91871444 | Disease modeling of core pre-mRNA splicing factor haploinsufficiency |
| Q36285876 | Disruption of the ERK/MAPK pathway in neural crest cells as a potential cause of Pierre Robin sequence. |
| Q91995541 | Dosage analysis of the 7q11.23 Williams region identifies BAZ1B as a major human gene patterning the modern human face and underlying self-domestication |
| Q90716957 | Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development |
| Q41229450 | Engineering human cell spheroids to model embryonic tissue fusion in vitro |
| Q26765978 | Epidemiology, Etiology, and Treatment of Isolated Cleft Palate |
| Q91864017 | Epigenetic influences on genetically triggered thoracic aortic aneurysm |
| Q37181010 | Epigenetic regulation of Sox4 during palate development |
| Q92542941 | Extracellular Matrix Composition and Remodeling: Current Perspectives on Secondary Palate Formation, Cleft Lip/Palate, and Palatal Reconstruction |
| Q38641260 | From Bench to Bedside and Back: Improving Diagnosis and Treatment of Craniofacial Malformations Utilizing Animal Models |
| Q36790968 | From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome |
| Q34125410 | Functional role of TGF-β receptors during palatal fusion in vitro |
| Q52688093 | Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. |
| Q90694169 | Genetic factors define CPO and CLO subtypes of nonsyndromicorofacial cleft |
| Q37183232 | Identification of candidate downstream targets of TGFβ signaling during palate development by genome-wide transcript profiling |
| Q35878640 | Implications of TGFβ on Transcriptome and Cellular Biofunctions of Palatal Mesenchyme |
| Q35268954 | Integration of comprehensive 3D microCT and signaling analysis reveals differential regulatory mechanisms of craniofacial bone development |
| Q42182097 | Loss-of-function mutation in the X-linked TBX22 promoter disrupts an ETS-1 binding site and leads to cleft palate |
| Q35893613 | Mechanisms of tissue fusion during development. |
| Q36760321 | Mice with Tak1 deficiency in neural crest lineage exhibit cleft palate associated with abnormal tongue development |
| Q37092620 | MicroRNA Profiling during Craniofacial Development: Potential Roles for Mir23b and Mir133b |
| Q37380184 | Modulation of lipid metabolic defects rescues cleft palate in Tgfbr2 mutant mice |
| Q36586217 | Molecular mechanisms of midfacial developmental defects |
| Q92260872 | Mouse embryonic palatal mesenchymal cells maintain stemness through the PTEN-Akt-mTOR autophagic pathway |
| Q37226205 | Noncanonical transforming growth factor β (TGFβ) signaling in cranial neural crest cells causes tongue muscle developmental defects |
| Q36275918 | Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis |
| Q26824725 | Roles of BMP signaling pathway in lip and palate development |
| Q35768123 | Roles of collagen and periostin expression by cranial neural crest cells during soft palate development |
| Q38974110 | Signalling pathways in trophic skeletal development and morphogenesis: Insights from studies on teleost fish |
| Q36648628 | Smad4-Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice |
| Q59795774 | TGF-β Signaling and the Epithelial-Mesenchymal Transition during Palatal Fusion |
| Q37551623 | TGFβ regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate |
| Q58613653 | Transcriptome analysis of Xenopus orofacial tissues deficient in retinoic acid receptor function |
| Q28592403 | Type III transforming growth factor beta receptor regulates vascular and osteoblast development during palatogenesis |
| Q64236020 | Wnt signaling in orofacial clefts: crosstalk, pathogenesis and models |
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